Allison Shapiro, PhD, MPH

Professional Titles

• Assistant Professor
• Director of Clinical Research for Section of Pediatric Endocrinology

Research Interests

My research focuses on the neural, behavioral, and cognitive consequences of pediatric diabetes and obesity across the life span. My current research portfolio includes investigating the neural underpinnings of disinhibited eating behavior in adolescents, neurocognitive function in youth-onset diabetes, and hypothalamic insulin sensitivity. I have recently expanded my work to investigating pathological aging as an emerging complication of youth-onset diabetes, as well as risk of cognitive impairment syndromes in adults with pre-diabetes and type 2 diabetes.

Publications

• Moore BF, Mueller NT, Perng W, Sauder KA, Hébert ET, Hoyt AT, Wymore EM, Boyle KE, Su EJ, Shapiro ALB, Kinney G, Sempio C, Klawitter J, Christians U, Dabelea D. Impact of prenatal exposure to delta 9-tetrahydrocannabinol and cannabidiol on birth size and postnatal growth trajectories. Pediatr Obes. 2025 Jan;20(1):e13187. PubMed PMID: 39681476
• Bettcher BM, Lopez Paniagua D, Wang Y, McConnell BV, Coughlan C, Carlisle TC, Thaker AA, Lippitt W, Filley CM, Pelak VS, Shapiro ALB, Heffernan KS, Potter H, Solano A, Boyd J, Carlson NE. Synergistic effects of GFAP and Aß42: Implications for white matter integrity and verbal memory across the cognitive spectrum. Brain Behav Immun Health. 2024 Oct;40:100834. PubMed PMID: 39206431
• Shapiro ALB, Lawless MC, Charlifue-Smith R, Johnson SL. Complementary food exposure and children's early understanding of food words: the approaching eating through language (APPEAL) study. Front Nutr. 2024;11:1237698. PubMed PMID: 38863587
• Shapiro ALB, Coughlan C, Bettcher BM, Pauley ME, Kim J, Bjornstad P, Rajic B, Truong J, Bell C, Choi YJ, Walker KA, Potter H, Liese AD, Dabelea D, Whitlow CT. Biomarkers of Neurodegeneration and Alzheimer's Disease Neuropathology in Adolescents and Young Adults with Youth-Onset Type 1 or Type 2 Diabetes: A Proof-of-Concept Study. Endocrines. 2024 Jun;5(2):197-213. PubMed PMID: 38764894
• Shapiro ALB, Tjaden AH, Edelstein SL, Kahn SE, Srikanthan P, Knowler WC, Venditti EM, Golden SH, Carmichael O, Luchsinger JA. The association of insulin responses and insulin sensitivity with cognition in adults with pre-diabetes: The Diabetes Prevention Program Outcomes Study. J Diabetes Complications. 2024 Jun;38(6):108764. PubMed PMID: 38701667
• Morales S, Bowers ME, Shuffrey L, Ziegler K, Troller-Renfree S, Hernandez A, Leach SC, McGrath M, Ola C, Leve LD, Nozadi SS, Swingler MM, Lai JS, Schweitzer JB, Fifer W, Camargo CA, Khurana Hershey GK, Shapiro ALB, Keating DP, Hartert TV, Deoni S, Ferrara A, Elliott AJ. Maternal education prospectively predicts child neurocognitive function: An environmental influences on child health outcomes study. Dev Psychol. 2024 Jun;60(6):1028-1040. PubMed PMID: 38407105
• Shapiro ALB, Coughlan C, Bettcher BM, Pauley ME, Kim J, Bjornstad P, Rajic B, Truong J, Bell C, Choi YJ, Walker KA, Potter H, Liese AD, Dabelea D, Whitlow CT. Biomarkers of Neurodegeneration and Alzheimer's Disease Neuropathology in Adolescents and Young Adults with Youth-Onset Type 1 or Type 2 Diabetes: A Proof-of-Concept Study. Endocrines. 2024 Jun;5(2):197-213. PubMed PMID: 38764894
• Shapiro ALB, Tjaden AH, Edelstein SL, Kahn SE, Srikanthan P, Knowler WC, Venditti EM, Golden SH, Carmichael O, Luchsinger JA. The association of insulin responses and insulin sensitivity with cognition in adults with pre-diabetes: The Diabetes Prevention Program Outcomes Study. J Diabetes Complications. 2024 Jun;38(6):108764. PubMed PMID: 38701667
• Morales S, Bowers ME, Shuffrey L, Ziegler K, Troller-Renfree S, Hernandez A, Leach SC, McGrath M, Ola C, Leve LD, Nozadi SS, Swingler MM, Lai JS, Schweitzer JB, Fifer W, Camargo CA, Khurana Hershey GK, Shapiro ALB, Keating DP, Hartert TV, Deoni S, Ferrara A, Elliott AJ. Maternal education prospectively predicts child neurocognitive function: An environmental influences on child health outcomes study. Dev Psychol. 2024 Jun;60(6):1028-1040. PubMed PMID: 38407105
• Cohen CC, Perng W, Sauder KA, Shapiro ALB, Starling AP, Friedman C, Felix JF, Küpers LK, Moore BF, Hébert JR, Shivappa N, Scherzinger A, Sundaram SS, Shankar K, Dabelea D. Maternal Diet Quality During Pregnancy and Offspring Hepatic Fat in Early Childhood: The Healthy Start Study. J Nutr. 2023 Apr;153(4):1122-1132. PubMed PMID: 36796482
• Brown AD, Liese AD, Shapiro ALB, Frongillo EA, Wilkening G, Fridriksson J, Merchant AT, Henkin L, Jensen ET, Reboussin BA, Shah AS, Marcovina S, Dolan LM, Dabelea D, Pihoker C, Mendoza JA. Household Food Insecurity and Cognition in Youth and Young Adults with Youth-Onset Diabetes. Pediatr Diabetes. 2023;2023. PubMed PMID: 38765732
• Shapiro ALB, Bellatorre A, Dabelea D, Stafford JM, D'Agostino R Jr, Shah AS, Urbina EM, Barrett CE, Pihoker C, Marcovina S, Liese AD, Mottl AK, Jensen ET, Wilkening G. Diabetes complications and cognitive function in young adults with youth-onset type 1 or type 2 diabetes: the SEARCH for Diabetes in Youth Study. Pediatr Diabetes. 2023;2023. PubMed PMID: 38706530
• Shapiro AL, Bellatorre A, Dabelea D, Stafford J, D’Agostino R, Shah A, Urbina EM, Barrett CE, Pihoker C, Marcovina S, Liese A, Mottl AK, Jensen ET, Wilkening G. (2023). Diabetes complications and cognitive function in youth with Type 1 or Type 2 diabetes: the SEARCH for Diabetes in Youth Study. Pediatric Diabetes.
• Brown AD, Liese AD, Shapiro AL, Frongillo EA, Wilkening G, Fridriksson J, Merchant AT, Henkin L, Jensen ET, Reboussin BA, Shah AS, Marcovina S, Dolan LM, Dabelea D, Pihoker C, Mendoza JA. (2023). Household Food Insecurity and Cognitive Function in Youth and Young Adults with Type 1 or Type 2 Diabetes. Pediatric Diabetes.
• Dark HE, Paterson C, Daya GN, Peng Z, Duggan MR, Bilgel M, An Y, Moghekar A, Davatzikos C, Resnick SM, Loupy K , Simpson M, Candia J, Mosley T, Coresh J, Palta P, Ferrucci L, Shapiro ALB, Williams SA, Walker KA. (2023). Proteomic indicators of health predict Alzheimer’s disease biomarker levels and dementia risk. Annals of Neurology.
• Moore BF, Sauder KA, Shapiro ALB, Crume T, Kinney GL, Dabelea D. Fetal Exposure to Cannabis and Childhood Metabolic Outcomes: The Healthy Start Study. J Clin Endocrinol Metab. 2022 Jun 16;107(7):e2862-e2869. PubMed PMID: 35357471
• Shapiro ALB, Lawless MC, Flesher A, Lattanzi K, Charlifue-Smith R, Johnson SL. Acceptance of a Novel Food is Related to Caregiver Perceptions of Infant and Toddler Food-related Receptive Language. J Nutr Educ Behav. 2022 Jul;54(7):684-690. PubMed PMID: 35643749
• Tommerdahl KL, Shapiro ALB, Nehus EJ, Bjornstad P. Early microvascular complications in type 1 and type 2 diabetes: recent developments and updates. Pediatr Nephrol. 2022 Jan;37(1):79-93. PubMed PMID: 33852054
• Johnson SL, Shapiro ALB, Moding KJ, Flesher A, Davis K, Fisher JO. Infant and Toddler Consumption of Sweetened and Unsweetened Lipid Nutrient Supplements After 2-Week Home Repeated Exposures. J Nutr. 2021 Sep 4;151(9):2825-2834. PubMed PMID: 34036363
• Tommerdahl KL, Shapiro ALB, Nehus EJ, Bjornstad P. Early microvascular complications in type 1 and type 2 diabetes: recent developments and updates. Pediatr Nephrol. 2021 Apr 14. [Epub ahead of print] PubMed PMID: 33852054
• Shapiro ALB, Dabelea D, Stafford JM, D'Agostino R, Pihoker C, Liese AD, Shah AS, Bellatorre A, Lawrence JM, Henkin L, Saydah S, Wilkening G. Cognitive Function in Adolescents and Young Adults With Youth-Onset Type 1 Versus Type 2 Diabetes: The SEARCH for Diabetes in Youth Study. Diabetes Care. 2021 Jun;44(6):1273-1280. PubMed PMID: 33905344
• Shapiro ALB, Moore BF, Sutton B, Wilkening G, Stence N, Dabelea D, Tregellas JR. In Utero Exposure to Maternal Overweight or Obesity is Associated with Altered Offspring Brain Function in Middle Childhood. Obesity (Silver Spring). 2020 Sep;28(9):1718-1725. PubMed PMID: 32772475
• Moore BF, Shapiro AL, Wilkening G, Magzamen S, Starling AP, Allshouse WB, Adgate JL, Dabelea D. Prenatal Exposure to Tobacco and Offspring Neurocognitive Development in the Healthy Start Study. J Pediatr. 2020 Mar;218:28-34.e2. PubMed PMID: 31759580