Big Data Analysis Challenge: Creating New Paradigms for Heart Failure Research, National Heart, Lung, and Blood Institute
(2020)
This Challenge seeks to foster innovation and address the need for new, open-source disease models that can define sub-categorizations of adult heart failure. These models will support new research hypotheses that may lead to further advancements in the management of this disorder.
Research Interests
My research is focused on using big data analysis to personalize management of heart disease, most notably heart failure. This includes development and use of various tools for prediction of survival and response to various therapies. I also am funded by a teaching grant aimed at establishing a data analysis team at the University of Zimbabwe.
Teaching
Assistant Professor
(2015)
School of Medicine,
Medicine
General cardiology, heart failure, cardiomyopathy, gender differences in cardiovascular disease, medical informatics, data warehousing, data mining, clinical decision support, personalized medicine
Medical Director
(2020)
School of Medicine,
Medicine
Colorado Center for Personalized Medicine
Associate Professor
(2021)
School of Medicine,
Medicine
General cardiology, heart failure, cardiomyopathy, gender differences in cardiovascular disease, medical informatics, data warehousing, data mining, clinical decision support, personalized medicine
Publications
Ravindra NG, Kao DP. Extracting Vocal Biomarkers for Pulmonary Congestion With a Smartphone App. JACC Heart Fail. 2022 Jan;10(1):50-51. PubMed PMID: 34969497
Kao D. Electronic health records and heart failure. Heart Fail Clin 2021;18(2):201-211.
Kao DP. Electronic Health Records and Heart Failure. Heart Fail Clin. 2022 Apr;18(2):201-211. PubMed PMID: 35341535
Anderson HD, Thant TM, Kao DP, Crooks KR, Mendola ND, Aquilante CL. Pharmacogenetic testing among patients with depression in a US managed care population. Clin Transl Sci. 2022 Jul;15(7):1644-1653. PubMed PMID: 35385214
Ravindra NG, Kao DP. Extracting Vocal Biomarkers for Pulmonary Congestion With a Smartphone App. JACC Heart Fail. 2022 Jan;10(1):50-51. PubMed PMID: 34969497
Cooney R, Scott JR, Mahowald M, Langen E, Sharma G, Kao DP, Davis MB. Heart rate as an early predictor of severe cardiomyopathy and increased mortality in peripartum cardiomyopathy. Clin Cardiol. 2022 Feb;45(2):205-213. PubMed PMID: 35129215
Johnson RK, Marker KM, Mayer D, Shortt J, Kao D, Barnes KC, Lowery JT, Gignoux CR. COVID-19 Surveillance in the Biobank at the Colorado Center for Personalized Medicine: Observational Study. JMIR Public Health Surveill. 2022 Jun 13;8(6):e37327. PubMed PMID: 35486493
Segar MW, Hall JL, Jhund PS, Powell-Wiley TM, Morris AA, Kao D, Fonarow GC, Hernandez R, Ibrahim NE, Rutan C, Navar AM, Stevens LM, Pandey A. Machine Learning-Based Models Incorporating Social Determinants of Health vs Traditional Models for Predicting In-Hospital Mortality in Patients With Heart Failure. JAMA Cardiol. 2022 Aug 1;7(8):844-854. PubMed PMID: 35793094
Hicks JK, El Rouby N, Ong HH, Schildcrout JS, Ramsey LB, Shi Y, Tang LA, Aquilante CL, Beitelshees AL, Blake KV, Cimino JJ, Davis BH, Empey PE, Kao DP, Lemkin DL, Limdi NA, Lipori GP, Rosenman MB, Skaar TC, Teal E, Tuteja S, Wiley LK, Williams H, Winterstein AG, Van Driest SL, Cavallari LH, Peterson JF. Opportunity for Genotype-Guided Prescribing Among Adult Patients in 11 U.S. Health Systems. Clin Pharmacol Ther. 2021 Jan 11. [Epub ahead of print] PubMed PMID: 33428770
Davis MB, Jarvie J, Gambahaya E, Lindenfeld J, Kao D. Risk Prediction for Peripartum Cardiomyopathy in Delivering Mothers: A Validated Risk Model: PPCM Risk Prediction Model. J Card Fail. 2021 Feb;27(2):159-167. PubMed PMID: 33388467
Hicks JK, El Rouby N, Ong HH, Schildcrout JS, Ramsey LB, Shi Y, Anne Tang L, Aquilante CL, Beitelshees AL, Blake KV, Cimino JJ, Davis BH, Empey PE, Kao DP, Lemkin DL, Limdi NA, P Lipori G, Rosenman MB, Skaar TC, Teal E, Tuteja S, Wiley LK, Williams H, Winterstein AG, Van Driest SL, Cavallari LH, Peterson JF. Opportunity for Genotype-Guided Prescribing Among Adult Patients in 11 US Health Systems. Clin Pharmacol Ther. 2021 Jul;110(1):179-188. PubMed PMID: 33428770
Stevens LM, Linstead E, Hall JL, Kao DP. Association Between Coffee Intake and Incident Heart Failure Risk: A Machine Learning Analysis of the FHS, the ARIC Study, and the CHS. Circ Heart Fail. 2021 Feb;14(2):e006799. PubMed PMID: 33557575
Singh I, Duca LM, Kao D, Chatfield KC, Khanna AD. Outcomes in hospitalisations of women with Turner syndrome compared to women without Turner syndrome. Cardiol Young. 2021 Oct;31(10):1667-1674. PubMed PMID: 33736722
Trinkley KE, Kroehl ME, Kahn MG, Allen LA, Bennett TD, Hale G, Haugen H, Heckman S, Kao DP, Kim J, Matlock DM, Malone DC, Page Nd RL, Stine J, Suresh K, Wells L, Lin CT. Applying Clinical Decision Support Design Best Practices With the Practical Robust Implementation and Sustainability Model Versus Reliance on Commercially Available Clinical Decision Support Tools: Randomized Controlled Trial. JMIR Med Inform. 2021 Mar 22;9(3):e24359. PubMed PMID: 33749610
Sottile PD, Albers D, DeWitt PE, Russell S, Stroh JN, Kao DP, Adrian B, Levine ME, Mooney R, Larchick L, Kutner JS, Wynia MK, Glasheen JJ, Bennett TD. Real-time electronic health record mortality prediction during the COVID-19 pandemic: a prospective cohort study. J Am Med Inform Assoc. 2021 Oct 12;28(11):2354-2365. PubMed PMID: 33973011
Doran B, Mei C, Varosy PD, Kao DP, Saxon LA, Feldman AM, DeMets D, Bristow MR. The Addition of a Defibrillator to Resynchronization Therapy Decreases Mortality in Patients With Nonischemic Cardiomyopathy. JACC Heart Fail. 2021 Jun;9(6):439-449. PubMed PMID: 33992570
Allen LA, Venechuk G, McIlvennan CK, Page RL 2nd, Knoepke CE, Helmkamp LJ, Khazanie P, Peterson PN, Pierce K, Harger G, Thompson JS, Dow TJ, Richards L, Huang J, Strader JR, Trinkley KE, Kao DP, Magid DJ, Buttrick PM, Matlock DD. An Electronically Delivered Patient-Activation Tool for Intensification of Medications for Chronic Heart Failure With Reduced Ejection Fraction: The EPIC-HF Trial. Circulation. 2021 Feb 2;143(5):427-437. PubMed PMID: 33201741
Tillman AR, Colborn KL, Scott KA, Davidson AJ, Khanna A, Kao D, McKenzie L, Ong T, Rausch CM, Duca LM, Daley MF, Coleman S, Costa E 3rd, Fernie E, Crume TL. Associations Between Socioeconomic Context and Congenital Heart Disease Related Outcomes in Adolescents and Adults. Am J Cardiol. 2021 Jan 15;139:105-115. PubMed PMID: 33203514
Anchouche K, Elharram M, Oulousian E, Razaghizad A, Avram R, Marquis-Gravel G, Randhawa VK, Nkulikiyinka R, Ni W, Fiuzat M, O'Connor C, Psotka MA, Fox J, Tyl B, Kao D, Sharma A. Use of Actigraphy (Wearable Digital Sensors to Monitor Activity) in Heart Failure Randomized Clinical Trials: A Scoping Review. Can J Cardiol. 2021 Sep;37(9):1438-1449. PubMed PMID: 34256087
Konigsberg IR, Barnes B, Campbell M, Davidson E, Zhen Y, Pallisard O, Boorgula MP, Cox C, Nandy D, Seal S, Crooks K, Sticca E, Harrison GF, Hopkinson A, Vest A, Arnold CG, Kahn MG, Kao DP, Peterson BR, Wicks SJ, Ghosh D, Horvath S, Zhou W, Mathias RA, Norman PJ, Porecha R, Yang IV, Gignoux CR, Monte AA, Taye A, Barnes KC. Host methylation predicts SARS-CoV-2 infection and clinical outcome. Commun Med (London). 2021;1(1):42. PubMed PMID: 35072167
Davis MB, Jarvie J, Gambahaya E, Lindenfeld J, Kao D. Risk Prediction for Peripartum Cardiomyopathy in Delivering Mothers: A Validated Risk Model: PPCM Risk Prediction Model. J Card Fail. 2020 Dec 31. [Epub ahead of print] PubMed PMID: 33388467
Ramsey LB, Ong HH, Schildcrout JS, Shi Y, Tang LA, Hicks JK, El Rouby N, Cavallari LH, Tuteja S, Aquilante CL, Beitelshees AL, Lemkin DL, Blake KV, Williams H, Cimino JJ, Davis BH, Limdi NA, Empey PE, Horvat CM, Kao DP, Lipori GP, Rosenman MB, Skaar TC, Teal E, Winterstein AG, Owusu Obeng A, Salyakina D, Gupta A, Gruber J, McCafferty-Fernandez J, Bishop JR, Rivers Z, Benner A, Tamraz B, Long-Boyle J, Peterson JF, Van Driest SL. Prescribing Prevalence of Medications With Potential Genotype-Guided Dosing in Pediatric Patients. JAMA Netw Open. 2020 Dec 1;3(12):e2029411. PubMed PMID: 33315113
Derington CG, King JB, Delate T, Botts SR, Kroehl M, Kao DP, Trinkley KE. Twice-daily versus once-daily lisinopril and losartan for hypertension: Real-world effectiveness and safety. PLoS One. 2020;15(12):e0243371. PubMed PMID: 33270787
Allen LA, Venechuk G, McIlvennan CK, Page Ii RL, Knoepke CE, Helmkamp LJ, Khazanie P, Peterson PN, Pierce K, Harger G, Thompson JS, Dow TJ, Richards L, Huang J, Strader JR, Trinkley KE, Kao DP, Magid DJ, Buttrick P, Matlock DD. An Electronically Delivered, Patient-Activation Tool for Intensification of Medications for Chronic Heart Failure with Reduced Ejection Fraction: The EPIC-HF Trial. Circulation. 2020 Nov 17. [Epub ahead of print] PubMed PMID: 33201741
Trinkley KE, Kahn MG, Bennett TD, Glasgow RE, Haugen H, Kao DP, Kroehl ME, Lin CT, Malone DC, Matlock DD. Integrating the Practical Robust Implementation and Sustainability Model With Best Practices in Clinical Decision Support Design: Implementation Science Approach. J Med Internet Res. 2020 Oct 29;22(10):e19676. PubMed PMID: 33118943
Stevens LM, Mortazavi BJ, Deo RC, Curtis L, Kao DP. Recommendations for Reporting Machine Learning Analyses in Clinical Research. Circ Cardiovasc Qual Outcomes. 2020 Oct;13(10):e006556. PubMed PMID: 33079589
Kao D, Larson C, Fletcher D, Stegner K. Clinical Decision Support May Link Multiple Domains to Improve Patient Care: Viewpoint. JMIR Med Inform. 2020 Oct 16;8(10):e20265. PubMed PMID: 33064106
Venechuk GE, Khazanie P, Page RL 2nd, Knoepke CE, Helmkamp LJ, Peterson PN, Pierce K, Thompson JS, Huang J, Strader JR, Dow TJ, Richards L, Trinkley KE, Kao DP, McIlvennan CK, Magid DJ, Buttrick PM, Matlock DD, Allen LA. An Electronically delivered, Patient-activation tool for Intensification of medications for Chronic Heart Failure with reduced ejection fraction: Rationale and design of the EPIC-HF trial. Am Heart J. 2020 Nov;229:144-155. PubMed PMID: 32866454
Bristow MR, Zisman LS, Altman NL, Gilbert EM, Lowes BD, Minobe WA, Slavov D, Schwisow JA, Rodriguez EM, Carroll IA, Keuer TA, Buttrick PM, Kao DP. Dynamic Regulation of SARS-Cov-2 Binding and Cell Entry Mechanisms in Remodeled Human Ventricular Myocardium. JACC Basic Transl Sci. 2020 Sep;5(9):871-883. PubMed PMID: 32838074
Lin CT, Bookman K, Sieja A, Markley K, Altman RL, Sippel J, Perica K, Reece L, Davis C, Horowitz E, Pisney L, Sottile PD, Kao D, Adrian B, Szkil M, Griffin J, Youngwerth J, Drew B, Pell J. Clinical informatics accelerates health system adaptation to the COVID-19 pandemic: examples from Colorado. J Am Med Inform Assoc. 2020 Dec 9;27(12):1955-1963. PubMed PMID: 32687152
Crume TL, Duca LM, Ong T, Kraus E, Scott K, Khanna A, Kao D, Rausch CM, McKenzie L, Daley MF, Coleman S, Kahn MG, Costa E 3rd, Davidson AJ. Population-level surveillance of congenital heart defects among adolescents and adults in Colorado: Implications of record linkage. Am Heart J. 2020 Aug;226:75-84. PubMed PMID: 32526532
Anderson HD, Crooks KR, Kao DP, Aquilante CL. The landscape of pharmacogenetic testing in a US managed care population. Genet Med. 2020 Jul;22(7):1247-1253. PubMed PMID: 32291400
Derington CG, Heath LJ, Kao DP, Delate T. Validation of algorithms to identify elective percutaneous coronary interventions in administrative databases. PLoS One. 2020;15(4):e0231100. PubMed PMID: 32255803
Aleong RG, Zipse MM, Tompkins C, Aftab M, Varosy P, Sauer W, Kao D. Analysis of Outcomes in 8304 Patients Undergoing Lead Extraction for Infection. J Am Heart Assoc. 2020 Apr 7;9(7):e011473. PubMed PMID: 32192410
Flint KM, Shah SJ, Lewis EF, Kao DP. Variation in clinical and patient-reported outcomes among complex heart failure with preserved ejection fraction phenotypes. ESC Heart Fail. 2020 Jun;7(3):811-824. PubMed PMID: 32160420
Aquilante CL, Kao DP, Trinkley KE, Lin CT, Crooks KR, Hearst EC, Hess SJ, Kudron EL, Lee YM, Liko I, Lowery J, Mathias RA, Monte AA, Rafaels N, Rioth MJ, Roberts ER, Taylor MR, Williamson C, Barnes KC. Clinical implementation of pharmacogenomics via a health system-wide research biobank: the University of Colorado experience. Pharmacogenomics. 2020 Apr;21(6):375-386. PubMed PMID: 32077359
Kao DP, Trinkley KE, Lin CT. Heart Failure Management Innovation Enabled by Electronic Health Records. JACC Heart Fail. 2020 Mar;8(3):223-233. PubMed PMID: 31926853
Kao D, Purohit S, Jhund P. Therapeutic futility and phenotypic heterogeneity in heart failure with preserved ejection fraction: what is the role of bionic learning?. Eur J Heart Fail. 2020 Jan;22(1):159-161. PubMed PMID: 31749260
Riordan M, Kao DP. Clinical phenotype differences in outcomes and responses in spironolactone in heart failure with preserved ejection fraction. Circulation. 2020;142:15229
Hyson P, Kao D. Biomarkers correspond with echo phenotype in HFpEF. Eur J Heart Fail. 22(Suppl S1):P508.
Kao DP. Intelligent Artificial Intelligence: Present Considerations and Future Implications of Machine Learning Applied to Electrocardiogram Interpretation. Circ Cardiovasc Qual Outcomes. 2019 Sep;12(9):e006021. PubMed PMID: 31525077
Psotka MA, Fiuzat M, Carson PE, Kao DP, Cerkvenik J, Schaber DE, Verta P, Kazmierski RT, Shinnar M, Stockbridge N, Unger EF, Zuckerman B, Butler J, Felker GM, Konstam MA, Lindenfeld J, Solomon SD, Teerlink JR, O'Connor CM, Abraham WT. Design of a "Lean" Case Report Form for Heart Failure Therapeutic Development. JACC Heart Fail. 2019 Nov;7(11):913-921. PubMed PMID: 31401097
Douglas PS, Carabello BA, Lang RM, Lopez L, Pellikka PA, Picard MH, Thomas JD, Varghese P, Wang TY, Weissman NJ, Wilgus R, Bozkurt B, Jneid H, Al-Khatib SM, Anderson HV, Gilstrap L, Graham GN, Jones GK, Kao D, Lopez L, Marcus G, Rymer J, Tcheng JE, Weintraub WS. 2019 ACC/AHA/ASE Key Data Elements and Definitions for Transthoracic Echocardiography: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Clinical Data Standards for Transthoracic Echocardiography) and the American Society of Echocardiography. J Am Soc Echocardiogr. 2019 Sep;32(9):1161-1248. PubMed PMID: 31248777
Trinkley KE, Blakeslee WW, Matlock DD, Kao DP, Van Matre AG, Harrison R, Larson CL, Kostman N, Nelson JA, Lin CT, Malone DC. Clinician preferences for computerised clinical decision support for medications in primary care: a focus group study. BMJ Health Care Inform. 2019 Apr;26(1):0. PubMed PMID: 31039120
Merrill M, Sweitzer NK, Lindenfeld J, Kao DP. Sex Differences in Outcomes and Responses to Spironolactone in Heart Failure With Preserved Ejection Fraction: A Secondary Analysis of TOPCAT Trial. JACC Heart Fail. 2019 Mar;7(3):228-238. PubMed PMID: 30819379
Piccini JP, Abraham WT, Dufton C, Carroll IA, Healey JS, van Veldhuisen DJ, Sauer WH, Anand IS, White M, Wilton SB, Aleong R, Rienstra M, Krueger SK, Ayala-Paredes F, Khaykin Y, Merkely B, Miloradovic V, Wranicz JK, Ilkhanoff L, Ziegler PD, Davis G, Emery LL, Marshall D, Kao DP, Bristow MR, Connolly SJ. Bucindolol for the Maintenance of Sinus Rhythm in a Genotype-Defined HF Population: The GENETIC-AF Trial. JACC Heart Fail. 2019 Jul;7(7):586-598. PubMed PMID: 31042551
Toni LS, Carroll IA, Jones KL, Schwisow JA, Minobe WA, Rodriguez EM, Altman NL, Lowes BD, Gilbert EM, Buttrick PM, Kao DP, Bristow MR. Correction: Sequential analysis of myocardial gene expression with phenotypic change: Use of cross-platform concordance to strengthen biologic relevance. PLoS One. 2019;14(10):e0224389. PubMed PMID: 31639152
Johnson-Sasso CP, Tompkins C, Kao DP, Walker LA. Marijuana use and short-term outcomes in patients hospitalized for acute myocardial infarction. PLoS One. 2018;13(7):e0199705. PubMed PMID: 29995914
Leary PJ, Kronmal RA, Bluemke DA, Buttrick PM, Jones KL, Kao DP, Kawut SM, Krieger EV, Lima JA, Minobe W, Ralph DD, Tedford RJ, Weiss NS, Bristow MR. Histamine H(2) Receptor Polymorphisms, Myocardial Transcripts, and Heart Failure (from the Multi-Ethnic Study of Atherosclerosis and Beta-Blocker Effect on Remodeling and Gene Expression Trial). Am J Cardiol. 2018 Jan 15;121(2):256-261. PubMed PMID: 29191567
Jarvie JL, Metz TD, Davis MB, Ehrig JC, Kao DP. Short-term risk of cardiovascular readmission following a hypertensive disorder of pregnancy. Heart. 2018 Jul;104(14):1187-1194. PubMed PMID: 29326108
Bristow MR, Kao DP, Breathett KK, Altman NL, Gorcsan J 3rd, Gill EA, Lowes BD, Gilbert EM, Quaife RA, Mann DL. Structural and Functional Phenotyping of the Failing Heart: Is the Left Ventricular Ejection Fraction Obsolete?. JACC Heart Fail. 2017 Nov;5(11):772-781. PubMed PMID: 29096787
Gambahaya ET, Hakim J, Kao D, Munyandu N, Matenga J. Peripartum cardiomyopathy among cardiovascular patients referred for echocardiography at Parirenyatwa Teaching Hospital, Harare, Zimbabwe. Cardiovasc J Afr. 2017 Jan Feb;28(1):8-13. PubMed PMID: 28262909
Maddox TM, Albert NM, Borden WB, Curtis LH, Ferguson TB Jr, Kao DP, Marcus GM, Peterson ED, Redberg R, Rumsfeld JS, Shah ND, Tcheng JE. The Learning Healthcare System and Cardiovascular Care: A Scientific Statement From the American Heart Association. Circulation. 2017 Apr 4;135(14):e826-e857. PubMed PMID: 28254835
Bandle B, Ward K, Min SJ, Drake C, McIlvennan CK, Kao D, Wald HL. Can Braden Score Predict Outcomes for Hospitalized Heart Failure Patients?. J Am Geriatr Soc. 2017 Jun;65(6):1328-1332. PubMed PMID: 28221672
Sucharov CC, Kao DP, Port JD, Karimpour-Fard A, Quaife RA, Minobe W, Nunley K, Lowes BD, Gilbert EM, Bristow MR. Myocardial microRNAs associated with reverse remodeling in human heart failure. JCI Insight. 2017 Jan 26;2(2):e89169. PubMed PMID: 28138556
Kao DP, Stevens LM, Hinterberg MA, Görg C. Phenotype-Specific Association of Single-Nucleotide Polymorphisms with Heart Failure and Preserved Ejection Fraction: a Genome-Wide Association Analysis of the Cardiovascular Health Study. J Cardiovasc Transl Res. 2017 Jun;10(3):285-294. PubMed PMID: 28105587
McIlvennan CK, Lindenfeld J, Kao DP. Sex differences and in-hospital outcomes in patients undergoing mechanical circulatory support implantation. J Heart Lung Transplant. 2017 Jan;36(1):82-90. PubMed PMID: 27773454
Kao DP, Lindenfeld J, Macaulay D, Birnbaum HG, Jarvis JL, Desai US, Page RL 2nd. Impact of a Telehealth and Care Management Program on All-Cause Mortality and Healthcare Utilization in Patients with Heart Failure. Telemed J E Health. 2016 Jan;22(1):2-11. PubMed PMID: 26218252
Kao D, Haigney MC, Mehler PS, Krantz M. Reply to Cataldo (2016): Arrhythmia associated with buprenorphine and methadone reported to the Food and Drug Administration. Addiction. 2016 Sep;111(9):1686-7. PubMed PMID: 27273759
Sandhu A, Kao D, Mehler PS, Haigney MC, Krantz MJ. Cardiovascular disorders associated with naloxone monotherapy and in fixed-dose combination with opioids: Data from international safety surveillance. Int J Cardiol. 2016 Jun 1;212:360-3. PubMed PMID: 27060723
Lindenfeld J, Cleveland JC Jr, Kao DP, White M, Wichman S, Bristow JC, Peterson V, Rodegheri-Brito J, Korst A, Blain-Nelson P, Sederberg J, Hunt SA, Gilbert EM, Ambardekar AV, Minobe W, Port JD, Bristow MR. Sex-related differences in age-associated downregulation of human ventricular myocardial ß1-adrenergic receptors. J Heart Lung Transplant. 2016 Mar;35(3):352-61. PubMed PMID: 26970472
Kao DP, Lindenfeld J, Macaulay D, Birnbaum HG, Jarvis JL, Desai US, Page RL 2nd. Impact of a Telehealth and Care Management Program on All-Cause Mortality and Healthcare Utilization in Patients with Heart Failure. Telemed J E Health. 2016 Jan;22(1):2-11. PubMed PMID: 26218252
Afana M, Brinjikji W, Kao D, Jackson E, Maddox TM, Childers D, Eagle KA, Davis MB. Characteristics and In-Hospital Outcomes of Peripartum Cardiomyopathy Diagnosed During Delivery in the United States From the Nationwide Inpatient Sample (NIS) Database. J Card Fail. 2016 Jul;22(7):512-9. PubMed PMID: 26923643
Katz DF, Turakhia MP, Sauer WH, Tzou WS, Heath RR, Zipse MM, Aleong RG, Varosy PD, Kao DP. Safety of Ventricular Tachycardia Ablation in Clinical Practice: Findings from 9,699 Hospital Discharge Records. Circ Arrhythm Electrophysiol. 2015 Feb 15. [Epub ahead of print] PubMed PMID: 25688143
Kao D, Lowes B, Gilbert E, Minobe W, Epperson LE, Meyer L, Ferguson D, Volkman K, Zolty R, Borg D, Quaife R, Bristow M. Therapeutic Molecular Phenotype of ß-blocker Associated Reverse-Remodeling in Nonischemic Dilated Cardiomyopathy. Circ Cardiovasc Genet. 2015 Jan 30. [Epub ahead of print] PubMed PMID: 25637602
Hinterberg MA, Kao DP, Bristow MR, Hunter LE, Port JD, Görg C. Peax: interactive visual analysis and exploration of complex clinical phenotype and gene expression association. Pac Symp Biocomput. 2015;:419-30. PubMed PMID: 25592601
Kao DP, Lewsey JD, Anand IS, Massie BM, Zile MR, Carson PE, McKelvie RS, Komajda M, McMurray JJ, Lindenfeld J. Characterization of subgroups of heart failure patients with preserved ejection fraction with possible implications for prognosis and treatment response. Eur J Heart Fail. 2015 Sep;17(9):925-35. PubMed PMID: 26250359
Kao DP, Haigney MC, Mehler PS, Krantz MJ. Arrhythmia associated with buprenorphine and methadone reported to the Food and Drug Administration. Addiction. 2015 Sep;110(9):1468-75. PubMed PMID: 26075588
Vehlow C, Kao DP, Bristow MR, Hunter LE, Weiskopf D, Görg C. Visual analysis of biological data-knowledge networks. BMC Bioinformatics. 2015 Apr 29;16:135. PubMed PMID: 25925016
Kao DP, Lowes BD, Gilbert EM, Minobe W, Epperson LE, Meyer LK, Ferguson DA, Volkman AK, Zolty R, Borg CD, Quaife RA, Bristow MR. Therapeutic Molecular Phenotype of ß-Blocker-Associated Reverse-Remodeling in Nonischemic Dilated Cardiomyopathy. Circ Cardiovasc Genet. 2015 Apr;8(2):270-83. PubMed PMID: 25637602
Hinterberg MA, Kao DP, Bristow MR, Hunter LE, Port JD, Görg C. Peax: interactive visual analysis and exploration of complex clinical phenotype and gene expression association. Pac Symp Biocomput. 2015;:419-30. PubMed PMID: 25592601
Katz DF, Turakhia MP, Sauer WH, Tzou WS, Heath RR, Zipse MM, Aleong RG, Varosy PD, Kao DP. Safety of ventricular tachycardia ablation in clinical practice: findings from 9699 hospital discharge records. Circ Arrhythm Electrophysiol. 2015 Apr;8(2):362-70. PubMed PMID: 25688143
67. Stevens LM, Linstead E, Hall JL, Kao DP. The association between coffee intake and incident heart failure risk – a machine learning analysis of the Framingham Heart, Atherosclerosis Risk in Communities, and Cardiovascular Health Studies. Circ Heart Fail. 2020.
63. Trinkley KE, Kahn MG, Bennett TD, Glasgow RE, Haugen H, Kao DP, Kroehl ME, Lin CT, Malone DC, Matlock DD. An implementation science approach to clinical decision support within electronic health records: integrating PRISM with CDS design best practices. J Med Internet Res 2020 [in press].
Biomedical Informatics, Specialized Training
(2008)
Conditions & Treatments
Heart and Circulation - Angina
Heart and Circulation - Arrhythmia
Heart and Circulation - Cardiomyopathy
Heart and Circulation - Circulatory Disorders
Heart and Circulation - Heart Attack
Heart and Circulation - Heart Diseases
Heart and Circulation - Coronary Disease
Heart and Circulation - Heart Diseases - Prevention
Heart and Circulation - Heart Failure
Heart and Circulation - Heart Valve Diseases
Genetic Conditions and Testing
Complementary and Alternative Therapies
Women's Health
Heart and Circulation
Clinical Interests
My clinical interests include heart failure, women's heart health,
heart disease in pregnancy,
clinical and genetic personalized cardiovascular medicine, and complementary medicine such as acupuncture and naturopathy.
Care Philosophy
I am committed to providing holistic, personalized care using all available considerations ranging from genetics to clinical conditions to quality of life to patient health care goals and treatment references.
Personal Interests
In my spare time, I enjoy making music, snowboarding, flyfishing, and travel.
Public Speaking Yes
Personalized Medicine
Women's Cardiovacsular Health
Big Data
Heart Failure
General Information
Medical Schools:
MD, Johns Hopkins University School of Medicine
(2003)
Undergraduate Schools:
BSc, Johns Hopkins University (MD)
(1998)
Internships:
Stanford Hospital and Clinics Program
(2004)
Residency Programs:
Stanford Hospital and Clinics Program, Chief Resident, Internal Medicine (2007)
Fellowships:
University of Colorado, Cardiology
(2014)
Stanford University Program, Biomedical Informatics Research
(2008)