Steve Anderson, PhD

Publications

• Prolactin-mediated regulation of lipid biosynthesis genes in vivo in the lactating mammary epithelial cell. Rudolph MC, Russell TD, Webb P, Neville MC, Anderson SM. Am J Physiol Endocrinol Metab. 2011 Jun;300(6):E1059-68. Epub 2011 Apr 5. PMID:21467304
• Lactation defect in a widely used MMTV-Cre transgenic line of mice. Yuan T, Wang Y, Pao L, Anderson SM, Gu H. PLoS One. 2011 Apr 29;6(4):e19233. PMID:21559430
• Loss of PKCd results in characteristics of Sjögren's syndrome including salivary gland dysfunction. Banninger GP, Cha S, Said MS, Pauley KM, Carter CJ, Onate M, Pauley BA, Anderson SM, Reyland ME. Oral Dis. 2011 Sep;17(6):601-9. doi: 10.1111/j.1601-0825.2011.01819.x. Epub 2011 Jun 27. PMID:21702866
• Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo. Young CD, Lewis AS, Rudolph MC, Ruehle MD, Jackman MR, Yun UJ, Ilkun O, Pereira R, Abel ED, Anderson SM. PLoS One. 2011;6(8):e23205. Epub 2011 Aug 3. PMID:21826239
• Pereira RO, Wende AR, Olsen C, Soto J, Rawlings T, Zhu Y, Anderson SM, Abel ED. Inducible overexpression of GLUT1 prevents mitochondrial dysfunction and attenuates structural remodeling in pressure overload but does not prevent left ventricular dysfunction. J Am Heart Assoc. 2013 Sep 19;2(5):e000301. PubMed PMID: 24052497
• Neville MC, Webb P, Ramanathan P, Mannino MP, Pecorini C, Monks J, Anderson SM, MacLean P. The insulin receptor plays an important role in secretory differentiation in the mammary gland. Am J Physiol Endocrinol Metab. 2013 Nov 1;305(9):E1103-14. PubMed PMID: 23982156
• M.C. Neville, S.M. Anderson, J.L. McManaman, T. M. Badger, M. Bunik, N. Contractor, T. Crume, D. Dabelea, S.M. Donovan, N. Forman, D.N. Frank, J.E. Friedman, J.B. German, A. Goldman, D. Hadsell, M. Hambidge, K. Hinde, N.D. Horseman, R.C. Hovey, E. Janoff, N. Krebs, C.B. Lebrilla5, D.G. Lemay, P.S. MacLean, P. Meier, A. Morrow, J. Neu, L.A. Nommsen-Rivers, M. Rijnkels, V. Seewaldt, B.D. Shur, J. VanHouten, P. Williamson, 2012. “Lactation and Neonatal Nutrition: Defining and Refining the Critical Questions,” J. Mammary Gland Biology and Neoplasia 17 (2): 167-188.
• Wahdan-Alaswad R, Fan Z, Edgerton SM, Liu B, Deng XS, Arnadottir SS, Richer JK, Anderson SM, Thor AD. Glucose promotes breast cancer aggression and reduces metformin efficacy. Cell Cycle. 2013 Dec 15;12(24):3759-69. PubMed PMID: 24107633
• Rudolph, M.C., N.K. Maluf, E.A. Wellberg, C.A. Johnson, R.C. Murphy, and S.M. Anderson, 2012. “Mammalian fatty acid synthase activity from crude lysates tracing (13)C-labelled substrates using gas chromatography-mass spectrometry.” Anal. Biochem. 428 (15): 158-166.
• E.D. Giles, E.A. Wellberg, D.P. Astling, S.M. Anderson, A.D. Thor, S. Jindal, A.C. Tan, P.S. Schedin, and P.S. MacLean, 2012. “Obesity and overfeeding affecting both tumor and systemic metabolism activates the progesterone receptor to contribute to postmenopausal breast cancer.” Cancer Research 72 (24): 6490-6501.
• Schmidt JW, Wehde BL, Sakamoto K, Triplett AA, Anderson SM, Tsichlis PN, Leone G, Wagner KU. Stat5 Regulates the PI3-kinase/Akt1 Pathway During Mammary Gland Development and Tumorigenesis. Mol Cell Biol. 2014 Jan 27. [Epub ahead of print] PubMed PMID: 24469394
• S.M. Anderson, P.S. MacLean, J.L. McManaman and M.C. Neville, 2013. “Lactation and its hormonal control.” Knobil and Neill’s Physiology of Reproduction, Fourth Edition. Tony M. Plant and Anthony Zeleznik, Editors. Elseiver, San Diego,CA.
• Wie SM, Adwan TS, Degregori J, Anderson SM, Reyland ME. Inhibiting Tyrosine Phosphorylation of Protein Kinase Cd (PKCd) Protects the Salivary Gland from Radiation Damage. J Biol Chem. 2014 Feb 25. [Epub ahead of print] PubMed PMID: 24569990
• E. Wellberg, M. Rudolph, and S.M. Anderson. “THRSP/S14 accelerates mammary tumor formation and enhances cell proliferation in MMTV-Neu mice.” 2012 Annual Meeting of the Endocrine Society, June 23-26, 2012. Houston, TX
• M. Rudolph, N.K. Maluf, E. Wellberg, A. Lewis, C. Johnson, N. Serkova, R. Murphy, and S. Anderson. “THRSP (Spot14) is necessary for complete de novo fatty acid synthesis in lactating mammary epithelium.” 2012 Annual Meeting of the Endocrine Society, June 23-26, 2012. Houston, TX
• Schmidt JW, Wehde BL, Sakamoto K, Triplett AA, Anderson SM, Tsichlis PN, Leone G, Wagner KU. Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis. Mol Cell Biol. 2014 Apr;34(7):1363-77. PubMed PMID: 24469394
• Wie SM, Adwan TS, DeGregori J, Anderson SM, Reyland ME. Inhibiting tyrosine phosphorylation of protein kinase Cd (PKCd) protects the salivary gland from radiation damage. J Biol Chem. 2014 Apr 11;289(15):10900-8. PubMed PMID: 24569990
• Cochrane DR, Wahdan-Alaswad R, Edgerton SM, Terrell KL, Spoelstra NS, Thor AD, Anderson SM, Richer JK. Metformin mediates upregulation of microRNA-193 triggers apoptosis by decreasing fatty acid synthase. 2012 San Antonio Breast Cancer Meeting. Cancer Res 72: (Suppl) 445s, 2012
• E.A. Wellberg, M.C. Rudolph, A. Lewis, and S.M. Anderson. Elevated THRSP/Spot14 expression is correlated with improved clinical outcome in breast cancer which is consistent with reduced metastasis and enhanced differentiation observed in the MMTV-Neu mouse model. 2013 Annual Meeting of the Endocrine Society, June 15-18, 2013.
• M.C. Rudolph, E.A. Wellberg, A.S. Lewis, C.A. Johnson, R.C. Murphy, and S.M. Anderson. Thyroid Hormone Responsive Protein (Spot14) Increases Fatty Acid Synthase Activity in vitro. 2013 Annual Meeting of the Endocrine Society, June 15-18, 2013.
• Rudolph MC, Wellberg EA, Lewis AS, Terrell KL, Merz AL, Maluf NK, Serkova NJ, Anderson SM. Thyroid hormone responsive protein Spot14 enhances catalysis of fatty acid synthase in lactating mammary epithelium. J Lipid Res. 2014 Apr 25;55(6):1052-1065. [Epub ahead of print] PubMed PMID: 24771867
• Wahdan-Alaswad RS, Cochrane DR, Spoelstra NS, Howe EN, Edgerton SM, Anderson SM, Thor AD, Richer JK. Metformin-induced killing of triple-negative breast cancer cells is mediated by reduction in fatty acid synthase via miRNA-193b. Horm Cancer. 2014 Dec;5(6):374-89. PubMed PMID: 25213330
• Wellberg EA, Anderson SM. FASNating targets of metformin in breast cancer stem-like cells. Horm Cancer. 2014 Dec;5(6):358-62. PubMed PMID: 25172609
• Wellberg EA, Rudolph MC, Lewis AS, Padilla-Just N, Jedlicka P, Anderson SM. Modulation of tumor fatty acids, through overexpression or loss of Thyroid Hormone Responsive Protein Spot 14, is associated with altered growth and metastasis. Breast Cancer Res. 2014 Dec 4;16(6):481. [Epub ahead of print] PubMed PMID: 25472762
• Heinz RE, Rudolph MC, Ramanathan P, Spoelstra NS, Butterfield KT, Webb PG, Babbs BL, Gao H, Chen S, Gordon MA, Anderson SM, Neville MC, Gu H, Richer JK. Constitutive expression of microRNA-150 in mammary epithelium suppresses secretory activation and impairs de novo lipogenesis. Development. 2016 Nov 15;143(22):4236-4248. PubMed PMID: 27729410
• Wellberg EA, Checkley LA, Giles ED, Johnson SJ, Oljira R, Wahdan-Alaswad R, Foright RM, Dooley G, Edgerton SM, Jindal S, Johnson GC, Richer JK, Kabos P, Thor AD, Schedin P, MacLean PS, Anderson SM. The Androgen Receptor Supports Tumor Progression After the Loss of Ovarian Function in a Preclinical Model of Obesity and Breast Cancer. Horm Cancer. 2017 Dec;8(5-6):269-285. PubMed PMID: 28741260
• Wellberg EA, Johnson S, Finlay-Schultz J, Lewis AS, Terrell KL, Sartorius CA, Abel ED, Muller WJ, Anderson SM. The glucose transporter GLUT1 is required for ErbB2-induced mammary tumorigenesis. Breast Cancer Res. 2016 Dec 20;18(1):131. PubMed PMID: 27998284
• Wellberg EA, Kabos P, Gillen AE, Jacobsen BM, Brechbuhl HM, Johnson SJ, Rudolph MC, Edgerton SM, Thor AD, Anderson SM, Elias A, Zhou XK, Iyengar NM, Morrow M, Falcone DJ, El-Hely O, Dannenberg AJ, Sartorius CA, MacLean PS. FGFR1 underlies obesity-associated progression of estrogen receptor-positive breast cancer after estrogen deprivation. JCI Insight. 2018 Jul 25;3(14). [Epub ahead of print] PubMed PMID: 30046001
• Grinman DY, Careaga VP, Wellberg EA, Dansey MV, Kordon EC, Anderson SM, Maier MS, Burton G, MacLean PS, Rudolph MC, Pecci A. Liver X receptor-a activation enhances cholesterol secretion in lactating mammary epithelium. Am J Physiol Endocrinol Metab. 2019 Jun 1;316(6):E1136-E1145. PubMed PMID: 30964702
• Ward AV, Anderson SM, Sartorius CA. Advances in Analyzing the Breast Cancer Lipidome and Its Relevance to Disease Progression and Treatment. J Mammary Gland Biol Neoplasia. 2021 Dec 16. [Epub ahead of print] PubMed PMID: 34914014
• DeLuca KF, Mick JE, Ide AH, Lima WC, Sherman L, Schaller KL, Anderson SM, Zhao N, Stasevich TJ, Varma D, Nilsson J, DeLuca JG. Generation and diversification of recombinant monoclonal antibodies. Elife. 2021 Dec 31;10. PubMed PMID: 34970967
• K. Li, X. Ji, R. Seeley, W.-C. Lee, Y. Shi, F. Song, X. Liao, C. Song, X. Huang, X. Luo, S.M. Anderson, W. Huang, and F Long, 2022. Impaired glucose metabolism underlies articular cartilage degeneration in osteoarthritis. FASEB J. 2022 Jun;36(6):e22377. doi: 10.1096/fj.202200485R.PMID: 35608871
• E.A. Wellberg, K.A. Corleto, L.A. Checkley, S. Jindal, G. Johnson, J.A. Higgins; S. Obeid, S.M. Anderson, A.D. Thor, P.J. Schedin, P.S. MacLean, and E.D. Giles, 2022. Preventing ovariectomy-induced weight gain decreases tumor burden in rodent models of obesity and postmenopausal breast cancer. Breast Cancer Research volume 24, Article number: 42. PMID: 35725493