Ryan Aleong, MD
Associate Adjoint Professor, Medicine-Cardiology

Medical School:
  • MD, University of Pittsburgh School of Medicine (1999)
Undergraduate School:
  • BSc, Brown University (RI) (1994)
  • Washington University/Barnes-Jewish Hospital/St. Louis Children's Hospital (2000)
  • Washington University/Barnes-Jewish Hospital/St. Louis Children's Hospital, Internal Medicine (2002)
  • University of Pittsburgh Medical Center, General Cardiology (2006)
  • Massachusetts General Hospital Program, Cardiac Electrophysiology (2008)
Languages: English
Department: Medicine-Cardiology


  • Sandhu A, Varosy PD, Du C, Aleong RG, Tumolo AZ, West JJ, Tzou WS, Curtis JP, Freeman JV, Friedman DJ, Hess PL. Device-Sizing and Associated Complications With Left Atrial Appendage Occlusion: Findings From the NCDR LAAO Registry. Circ Cardiovasc Interv. 2022 Dec 6;:e012183. [Epub ahead of print] PubMed PMID: 36472194
  • Edward JA, Chang SC, Gill EA, Tzou WS, Aleong RG. Esophago-Pericardial Fistula as a Rare and Life-Threatening Complication of Epicardial Ventricular Tachycardia Ablation. JACC Case Rep. 2022 Sep 21;4(18):1180-1185. PubMed PMID: 36213880
  • Sabzwari SRA, Rosenberg MA, Mann J, Cerbin L, Barrett C, Garg L, Aleong RG, Sandhu A, West J, Tumolo AZ, Varosy PD, Sauer WH, Zipse MM, Tzou WS. Limitations of Unipolar Signals in Guiding Successful Outflow Tract Premature Ventricular Contraction Ablation. JACC Clin Electrophysiol. 2022 Jul;8(7):843-853. PubMed PMID: 35643806
  • Groh WJ, Bhakta D, Tomaselli GF, Aleong RG, Teixeira RA, Amato A, Asirvatham SJ, Cha YM, Corrado D, Duboc D, Goldberger ZD, Horie M, Hornyak JE, Jefferies JL, Kääb S, Kalman JM, Kertesz NJ, Lakdawala NK, Lambiase PD, Lubitz SA, McMillan HJ, McNally EM, Milone M, Namboodiri N, Nazarian S, Patton KK, Russo V, Sacher F, Santangeli P, Shen WK, Sobral Filho DC, Stambler BS, Stöllberger C, Wahbi K, Wehrens XHT, Weiner MM, Wheeler MT, Zeppenfeld K. 2022 HRS expert consensus statement on evaluation and management of arrhythmic risk in neuromuscular disorders. Heart Rhythm. 2022 Oct;19(10):e61-e120. PubMed PMID: 35500790
  • Abraham WT, Piccini JP, Dufton C, Carroll IA, Healey JS, O'Connor CM, Marshall D, Aleong R, van Veldhuisen DJ, Rienstra M, Wilton SB, White M, Sauer WH, Anand IS, Huebler SP, Connolly SJ, Bristow MR. Dose-limiting, adverse event-associated bradycardia with ß-blocker treatment of atrial fibrillation in the GENETIC-AF trial. Heart Rhythm O2. 2022 Feb;3(1):40-49. PubMed PMID: 35243434
  • Kim RS, Simon S, Powers B, Sandhu A, Sanchez J, Borne RT, Tumolo A, Zipse M, West JJ, Aleong R, Tzou W, Rosenberg MA. Machine Learning Methodologies for Prediction of Rhythm-Control Strategy in Patients Diagnosed With Atrial Fibrillation: Observational, Retrospective, Case-Control Study. JMIR Med Inform. 2021 Dec 6;9(12):e29225. PubMed PMID: 34874889
  • Kunkel M, Rothstein P, Sauer P, Zipse MM, Sandhu A, Tumolo AZ, Borne RT, Aleong RG, Cleveland JC Jr, Fullerton D, Pal JD, Davies AS, Lane C, Nguyen DT, Sauer WH, Tzou WS. Open surgical ablation of ventricular tachycardia: Utility and feasibility of contemporary mapping and ablation tools. Heart Rhythm O2. 2021 Jun;2(3):271-279. PubMed PMID: 34337578
  • Piccini JP, Dufton C, Carroll IA, Healey JS, Abraham WT, Khaykin Y, Aleong R, Krueger SK, Sauer WH, Wilton SB, Rienstra M, van Veldhuisen DJ, Anand IS, White M, Camm AJ, Ziegler PD, Marshall D, Bristow MR, Connolly SJ. Bucindolol Decreases Atrial Fibrillation Burden in Patients With Heart Failure and the ADRB1 Arg389Arg Genotype. Circ Arrhythm Electrophysiol. 2021 Aug;14(8):e009591. PubMed PMID: 34270905
  • Aleong RG, Zipse MM, Tompkins C, Aftab M, Varosy P, Sauer W, Kao D. Analysis of Outcomes in 8304 Patients Undergoing Lead Extraction for Infection. J Am Heart Assoc. 2020 Apr 7;9(7):e011473. PubMed PMID: 32192410
  • Aleong RG, Chang S. Can Ablation for Atrial Fibrillation Be Simpler?: Are Urethral Catheters Unnecessary in Atrial Fibrillation Ablations?. JACC Clin Electrophysiol. 2020 Feb;6(2):191-192. PubMed PMID: 32081222
  • Sandhu A, Zipse MM, Borne RT, Aleong RG, Tompkins C, Schuller J, Rosenberg M, Varosy PD, Tzou WS, Nguyen DT, Sauer WH. Esophageal position, measured luminal temperatures, and risk of atrioesophageal fistula with atrial fibrillation ablation. Pacing Clin Electrophysiol. 2019 Feb 19. [Epub ahead of print] PubMed PMID: 30779183
  • Fleeman BE, Aleong RG. Optimal Strategies to Reduce Inappropriate Implantable Cardioverter-defibrillator Shocks. J Innov Card Rhythm Manag. 2019 Apr;10(4):3623-3632. PubMed PMID: 32477727
  • Aleong RG, Sandhu A. Does Coffee Reduce the Risk of Atrial Fibrillation?. J Am Heart Assoc. 2019 Aug 6;8(15):e012862. PubMed PMID: 31378125
  • Piccini JP, Abraham WT, Dufton C, Carroll IA, Healey JS, van Veldhuisen DJ, Sauer WH, Anand IS, White M, Wilton SB, Aleong R, Rienstra M, Krueger SK, Ayala-Paredes F, Khaykin Y, Merkely B, Miloradovic V, Wranicz JK, Ilkhanoff L, Ziegler PD, Davis G, Emery LL, Marshall D, Kao DP, Bristow MR, Connolly SJ. Bucindolol for the Maintenance of Sinus Rhythm in a Genotype-Defined HF Population: The GENETIC-AF Trial. JACC Heart Fail. 2019 Jul;7(7):586-598. PubMed PMID: 31042551
  • Sandhu A, Tzou W, Ream K, Valle J, Tompkins C, Nguyen DT, Sauer WH, Carroll JD, Messenger J, Aleong RG. Heart Block After Discharge in Patients Undergoing TAVR With Latest-Generation Valves. J Am Coll Cardiol. 2018 Feb 6;71(5):577-578. PubMed PMID: 29406864
  • Piccini JP, Connolly SJ, Abraham WT, Healey JS, Steinberg BA, Al-Khalidi HR, Dignacco P, van Veldhuisen DJ, Sauer WH, White M, Wilton SB, Anand IS, Dufton C, Marshall DA, Aleong RG, Davis GW, Clark RL, Emery LL, Bristow MR. A genotype-directed comparative effectiveness trial of Bucindolol and metoprolol succinate for prevention of symptomatic atrial fibrillation/atrial flutter in patients with heart failure: Rationale and design of the GENETIC-AF trial. Am Heart J. 2018 May;199:51-58. PubMed PMID: 29754666
  • Tzou WS, Rothstein PA, Cowherd M, Zipse MM, Tompkins C, Marzec L, Aleong RG, Schuller JL, Varosy PD, Borne RT, Mathew J, Tumolo A, Sandhu A, Nguyen DT, Sauer WH. Repeat ablation of refractory ventricular arrhythmias in patients with nonischemic cardiomyopathy: Impact of midmyocardial substrate and role of adjunctive ablation techniques. J Cardiovasc Electrophysiol. 2018 Oct;29(10):1403-1412. PubMed PMID: 30033528
  • Aleong RG, Sauer WH. Paradox of Appropriate Implantable Cardioverter-Defibrillator Therapy: Saving Lives But Revealing an Increased Mortality Risk. J Am Heart Assoc. 2017 Aug 19;6(8). PubMed PMID: 28862958
  • Sandhu A, Borne RT, Mam C, Bunch TJ, Aleong RG. Double jeopardy: long QT3 and Brugada syndromes. Clin Case Rep. 2017 Aug;5(8):1315-1319. PubMed PMID: 28781849
  • Zipse MM, Aleong RG. Acquired Pulmonary Vein Isolation in a Patient with Friedreich Ataxia. Card Electrophysiol Clin. 2016 Mar;8(1):151-3. PubMed PMID: 26920184
  • Nguyen DT, Tzou WS, Brunnquell M, Zipse M, Schuller JL, Zheng L, Aleong RA, Sauer WH. Clinical and biophysical evaluation of variable bipolar configurations during radiofrequency ablation for treatment of ventricular arrhythmias. Heart Rhythm. 2016 Nov;13(11):2161-2171. PubMed PMID: 27424078
  • Zipse MM, Aleong RG. Acquired Pulmonary Vein Isolation in a Patient with Friedreich Ataxia. Card Electrophysiol Clin. 2016 Mar;8(1):151-3. PubMed PMID: 26920184
  • Katz DF, Turakhia MP, Sauer WH, Tzou WS, Heath RR, Zipse MM, Aleong RG, Varosy PD, Kao DP. Safety of Ventricular Tachycardia Ablation in Clinical Practice: Findings from 9,699 Hospital Discharge Records. Circ Arrhythm Electrophysiol. 2015 Feb 15. [Epub ahead of print] PubMed PMID: 25688143
  • Sandhu A, Krantz MJ, Taylor M, Aleong RG, Stichman J, Schuller JL. Syncope and cardiac arrest during strenuous exercise associated with a novel mutation in LQTS1. Clin Case Rep. 2015 Dec;3(12):971-4. PubMed PMID: 26734131
  • Aleong RG, Mulvahill MJ, Halder I, Carlson NE, Singh M, Bloom HL, Dudley SC, Ellinor PT, Shalaby A, Weiss R, Gutmann R, Sauer WH, Narayanan K, Chugh SS, Saba S, London B. Left Ventricular Dilatation Increases the Risk of Ventricular Arrhythmias in Patients With Reduced Systolic Function. J Am Heart Assoc. 2015 Jul 31;4(8):e001566. PubMed PMID: 26231842
  • Aryana A, Singh SM, Kowalski M, Pujara DK, Cohen AI, Singh SK, Aleong RG, Banker RS, Fuenzalida CE, Prager NA, Bowers MR, D'Avila A, O'Neill PG. Acute and Long-Term Outcomes of Catheter Ablation of Atrial Fibrillation Using the Second-Generation Cryoballoon versus Open-Irrigated Radiofrequency: A Multicenter Experience. J Cardiovasc Electrophysiol. 2015 Aug;26(8):832-9. PubMed PMID: 25917655
  • Katz DF, Turakhia MP, Sauer WH, Tzou WS, Heath RR, Zipse MM, Aleong RG, Varosy PD, Kao DP. Safety of ventricular tachycardia ablation in clinical practice: findings from 9699 hospital discharge records. Circ Arrhythm Electrophysiol. 2015 Apr;8(2):362-70. PubMed PMID: 25688143
  • Narayanan K, Reinier K, Teodorescu C, Uy-Evanado A, Aleong R, Chugh H, Nichols GA, Gunson K, London B, Jui J, Chugh SS. Left ventricular diameter and risk stratification for sudden cardiac death. J Am Heart Assoc. 2014 Sep 16;3(5):e001193. PubMed PMID: 25227407
  • Zipse MM, Sauer WH, Varosy PD, Aleong RG, Nguyen DT. Inappropriate shocks due to subcutaneous air in a patient with a subcutaneous cardiac defibrillator. Circ Arrhythm Electrophysiol. 2014 Aug;7(4):768-70. PubMed PMID: 25140025
  • Aleong RG, Sauer WH, Davis G, Bristow MR. New-onset atrial fibrillation predicts heart failure progression. Am J Med. 2014 Oct;127(10):963-71. PubMed PMID: 24931393
  • Bristow MR, Aleong RG. Treatment of the heart failure patient with atrial fibrillation: a major unmet need. JACC Heart Fail. 2013 Feb;1(1):29-30. PubMed PMID: 24621796
  • Aleong RG, Sauer WH, Davis G, Murphy GA, Port JD, Anand IS, Fiuzat M, O'Connor CM, Abraham WT, Liggett SB, Bristow MR. Prevention of Atrial Fibrillation by Bucindolol Is Dependent on the Beta(1)389 Arg/Gly Adrenergic Receptor Polymorphism. JACC Heart Fail. 2013 Aug 1;1(4):338-344. PubMed PMID: 24159564
  • Olson MD, Phreaner N, Schuller JL, Nguyen DT, Katz DF, Aleong RG, Tzou WS, Sung R, Varosy PD, Sauer WH. Effect of catheter movement and contact during application of radiofrequency energy on ablation lesion characteristics. J Interv Card Electrophysiol. 2013 Nov;38(2):123-9. PubMed PMID: 24022756
  • Tzou WS, Nguyen DT, Aleong RG, Varosy PD, Katz DF, Heath RR, Schuller JL, Lowery CM, Lewkowiez L, Sauer WH. Endocardial electrogram characteristics of epicardial ventricular arrhythmias. J Cardiovasc Electrophysiol. 2013 Jun;24(6):649-54. PubMed PMID: 23397974
  • Aleong RG, Sauer WH, Robertson AD, Liggett SB, Bristow MR. Adrenergic receptor polymorphisms and prevention of ventricular arrhythmias with bucindolol in patients with chronic heart failure. Circ Arrhythm Electrophysiol. 2013 Feb;6(1):137-43. PubMed PMID: 23275278
  • Kao DP, Davis G, Aleong R, O'Connor CM, Fiuzat M, Carson PE, Anand IS, Plehn JF, Gottlieb SS, Silver MA, Lindenfeld J, Miller AB, White M, Murphy GA, Sauer W, Bristow MR. Effect of bucindolol on heart failure outcomes and heart rate response in patients with reduced ejection fraction heart failure and atrial fibrillation. Eur J Heart Fail. 2013 Mar;15(3):324-33. PubMed PMID: 23223178
  • Lowery CM, Tzou WS, Aleong RG, Nguyen DT, Varosy PD, Katz DF, Heath RR, Schuller JL, Lewkowiez L, Sauer WH. Use of stored implanted cardiac defibrillator electrograms in catheter ablation of ventricular fibrillation. Pacing Clin Electrophysiol. 2013 Jan;36(1):76-85. PubMed PMID: 23078144
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Specialty Information

  • Internal Medicine, Board Certification (2003)
  • General Cardiology, Board Certification (2006)
  • Cardiology, Board Certification (2006)
  • Cardiac Electrophysiology, Board Certification (2008)
Conditions & Treatments
  • Heart and Circulation - Arrhythmia
  • Heart and Circulation - Heart Diseases
  • Heart and Circulation
Clinical Interests
I am interested in all aspect of treating abnormal cardiac rhythms. With regard to abnormal fast cardiac rhythms, I treat both supraventricular and ventricular tachycardias. I have a special interest in ablation and medication management for atrial fibrillation. For device management, I implant both pacemakers and defibrillators including biventricular devices. I also serve as the director of the lead extraction program.

Care Philosophy
I believe that our mission is to help patients understand different treatment options and to safely implement the most effective treatment strategy.

Personal Interests
I am an avid runner and enjoy spending time with my family.

General Information

Medical Schools:
  • MD, University of Pittsburgh School of Medicine (1999)
Undergraduate Schools:
  • BSc, Brown University (RI) (1994)
  • Washington University/Barnes-Jewish Hospital/St. Louis Children's Hospital (2000)
Residency Programs:
  • Washington University/Barnes-Jewish Hospital/St. Louis Children's Hospital, Internal Medicine (2002)
  • University of Pittsburgh Medical Center, General Cardiology (2006)
  • Massachusetts General Hospital Program, Cardiac Electrophysiology (2008)
Languages: English
Department: Medicine-Cardiology
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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