I am an investigator in a number of clinical outcome studies specifically involving hypospadias, undescended testicles and patients with hydronephrosis. I have a long term research interest in the clinical problems associated with patients born with imperforate anus and work closely with the Pediatric Surgeons at The Children's Hospital to provide comprehensive multidisciplinary care to these patients.
Teaching
Professor
(2008)
School of Medicine,
Surgery
Publications
Reppucci ML, Alaniz VI, Wehrli LA, Torre L, Wood D, Wilcox DT, Appiah LC, Peña A, Bischoff A. Reproductive and family building considerations for female patients with anorectal and urogenital malformations. J Pediatr Surg. 2022 Sep 19. [Epub ahead of print] PubMed PMID: 36229236
Moore RP, Burjek NE, Brockel MA, Strine AC, Acks A, Boxley PJ, Chidambaran V, Vricella GJ, Chu DI, Sankaran-Raval M, Zee RS, Cladis FP, Chaudhry R, O'Reilly-Shah VN, Ahn JJ, Rove KO. Evaluating the role for regional analgesia in children with spina bifida: a retrospective observational study comparing the efficacy of regional versus systemic analgesia protocols following major urological surgery. Reg Anesth Pain Med. 2022 Sep 27. [Epub ahead of print] PubMed PMID: 36167478
Reppucci ML, Wehrli LA, Wilcox D, Ketzer J, Pena A, de la Torre L, Bischoff A, Wood D. Patient-reported urinary outcomes in adult males with congenital colorectal conditions. Pediatr Surg Int. 2022 Sep 23. [Epub ahead of print] PubMed PMID: 36151341
Reppucci ML, Wehrli LA, Wilcox D, Ketzer J, Pena A, de la Torre L, Bischoff A, Wood D. Sexual function and fertility of adult males with anorectal malformations or Hirschsprung disease. Pediatr Surg Int. 2022 Sep 23. [Epub ahead of print] PubMed PMID: 36151340
Vargas MC, Wehrli LA, Louiselle A, Ketzer J, Reppucci ML, Juddy-Glossy L, Alaniz VI, Wilcox DT, Wood DN, Peña A, De La Torre L, Bischoff A. Do adult patients with congenital colorectal conditions know their diagnosis?. Pediatr Surg Int. 2022 Sep 21. [Epub ahead of print] PubMed PMID: 36129533
Wood D, Wilcox D. Hypospadias: lessons learned. An overview of incidence, epidemiology, surgery, research, complications, and outcomes. Int J Impot Res. 2022 Mar 29. [Epub ahead of print] PubMed PMID: 35352016
Iguchi N, Hecht SL, Gao D, Wilcox DT, Malykhina AP, Cost NG. Sexual dimorphic impacts of systemic vincristine on lower urinary tract function. Sci Rep. 2022 Mar 24;12(1):5113. PubMed PMID: 35332157
Andolfi C, Lombardo AM, Aizen J, Recabal X, Walker JP, Barashi NS, Reed F, Lopez PJ, Wilcox DT, Gundeti MS. Laparoscopic and robotic pyeloplasty as minimally invasive alternatives to the open approach for the treatment of uretero-pelvic junction obstruction in infants: a multi-institutional comparison of outcomes and learning curves. World J Urol. 2022 Apr;40(4):1049-1056. PubMed PMID: 35044490
Hecht SL, Quach A, Gao D, Brazell A, Beltran G, Holbrook S, Gore L, Iguchi N, Malykhina A, Wilcox D, Cost NG. A prospective survey study of lower urinary tract dysfunction in childhood cancer survivors after vincristine and/or doxorubicin chemotherapy. Pediatr Blood Cancer. 2021 Oct;68(10):e29226. PubMed PMID: 34245214
Wood D, Wilcox D. Why look back in anger? Masculinizing surgery in patients with DSD. Nat Rev Urol. 2021 Jul;18(7):385-386. PubMed PMID: 33837368
Iguchi N, Carrasco A Jr, Xie AX, Pineda RH, Malykhina AP, Wilcox DT. Functional constipation induces bladder overactivity associated with upregulations of Htr2 and Trpv2 pathways. Sci Rep. 2021 Jan 13;11(1):1149. PubMed PMID: 33441874
Alaniz VI, Wilcox DT, Arnold M, Bodmer JL, de la Torre L, Peña A, Bischoff A. Neovagina stricture complicated by high-grade dysplasia in a patient with history of cloaca and ulcerative colitis: a case report and review of the literature. Pediatr Surg Int. 2021 Apr;37(4):491-494. PubMed PMID: 33433664
Delcont M, Guglielmetti LC, Rajbhandari N, Walker J, Wilcox D, Vuille-Dit-Bille RN. Bladder Duplication - A Case Series. Urology. 2021 Mar;149:199-205. PubMed PMID: 33189736
Han DS, Brockel MA, Boxley PJ, Dönmez MI, Saltzman AF, Wilcox DT, Rove KO. Enhanced recovery after surgery and anesthetic outcomes in pediatric reconstructive urologic surgery. Pediatr Surg Int. 2021 Jan;37(1):151-159. PubMed PMID: 33161476
Hecht SL, Quach A, Gao D, Brazell A, Beltran G, Holbrook S, Gore L, Iguchi N, Malykhina A, Wilcox D, Cost NG. A prospective survey study of lower urinary tract dysfunction in childhood cancer survivors after vincristine and/or doxorubicin chemotherapy. Pediatr Blood Cancer. 2021 Oct;68(10):e29226. PubMed PMID: 34245214
Wood D, Wilcox D. Why look back in anger? Masculinizing surgery in patients with DSD. Nat Rev Urol. 2021 Jul;18(7):385-386. PubMed PMID: 33837368
Iguchi N, Carrasco A Jr, Xie AX, Pineda RH, Malykhina AP, Wilcox DT. Functional constipation induces bladder overactivity associated with upregulations of Htr2 and Trpv2 pathways. Sci Rep. 2021 Jan 13;11(1):1149. PubMed PMID: 33441874
Alaniz VI, Wilcox DT, Arnold M, Bodmer JL, de la Torre L, Peña A, Bischoff A. Neovagina stricture complicated by high-grade dysplasia in a patient with history of cloaca and ulcerative colitis: a case report and review of the literature. Pediatr Surg Int. 2021 Apr;37(4):491-494. PubMed PMID: 33433664
Delcont M, Guglielmetti LC, Rajbhandari N, Walker J, Wilcox D, Vuille-Dit-Bille RN. Bladder Duplication - A Case Series. Urology. 2021 Mar;149:199-205. PubMed PMID: 33189736
Han DS, Brockel MA, Boxley PJ, Dönmez MI, Saltzman AF, Wilcox DT, Rove KO. Enhanced recovery after surgery and anesthetic outcomes in pediatric reconstructive urologic surgery. Pediatr Surg Int. 2021 Jan;37(1):151-159. PubMed PMID: 33161476
Delcont M, Guglielmetti LC, Rajbhandari N, Walker J, Wilcox D, Vuille-Dit-Bille RN. Bladder duplication- a case series. Urology. 2020 Nov 12. [Epub ahead of print] PubMed PMID: 33189736
Rove KO, Strine AC, Wilcox DT, Vricella GJ, Welch TP, VanderBrink B, Chu DI, Chaudhry R, Zee RS, Brockel MA. Design and development of the Pediatric Urology Recovery After Surgery Endeavor (PURSUE) multicentre pilot and exploratory study. BMJ Open. 2020 Nov 23;10(11):e039035. PubMed PMID: 33234633
Han DS, Brockel MA, Boxley PJ, Dönmez MI, Saltzman AF, Wilcox DT, Rove KO. Enhanced recovery after surgery and anesthetic outcomes in pediatric reconstructive urologic surgery. Pediatr Surg Int. 2020 Nov 7. [Epub ahead of print] PubMed PMID: 33161476
Guglielmetti LC, Delcont M, Walker J, Wilcox D, Vuille-Dit-Bille RN. Urethral duplication-Epidemiology, diagnosis, and treatment in a case series of 19 patients. J Pediatr Urol. 2020 Jun;16(3):385.e1-385.e9. PubMed PMID: 32197934
Higgins M, Smith DE, Gao D, Wilcox D, Cost NG, Saltzman AF. The impact of age at orchiopexy on testicular cancer outcomes. World J Urol. 2020 Oct;38(10):2531-2536. PubMed PMID: 31781896
Guglielmetti LC, Delcont M, Walker J, Wilcox D, Vuille-Dit-Bille RN. Urethral duplication-Epidemiology, diagnosis, and treatment in a case series of 19 patients. J Pediatr Urol. 2020 Jun;16(3):385.e1-385.e9. PubMed PMID: 32197934
Higgins M, Smith DE, Gao D, Wilcox D, Cost NG, Saltzman AF. The impact of age at orchiopexy on testicular cancer outcomes. World J Urol. 2020 Oct;38(10):2531-2536. PubMed PMID: 31781896
Bischoff A, Trecartin A, Alaniz V, Hecht S, Wilcox DT, Peña A. A cloacal anomaly is not a disorder of sex development. Pediatr Surg Int. 2019 Sep;35(9):985-987. PubMed PMID: 31256297
Hecht S, Hall J, Ketzer J, Walker J, Trecartin A, Wilcox D, Peña A, Bischoff A. Ectopic ureters in anorectal malformations. Pediatr Surg Int. 2019 Sep;35(9):1005-1008. PubMed PMID: 31278478
Iguchi N, Dönmez MI, Carrasco A Jr, Wilcox DT, Pineda RH, Malykhina AP, Cost NG. Doxorubicin induces detrusor smooth muscle impairments through myosin dysregulation, leading to a risk of lower urinary tract dysfunction. Am J Physiol Renal Physiol. 2019 Jul 1;317(1):F197-F206. PubMed PMID: 31066574
Bischoff A, Bealer J, Wilcox DT, Peña A. Error traps and culture of safety in anorectal malformations. Semin Pediatr Surg. 2019 Jun;28(3):131-134. PubMed PMID: 31171146
Danzig MR, Wild TT, Holbrook S, Wilcox DT. Distribution of a photographic atlas did not reduce postoperative care utilization after pediatric circumcision or the indispensability of the pediatric urology clinic nurse. J Pediatr Urol. 2019 May;15(3):227.e1-227.e6. PubMed PMID: 30940432
Dönmez MI, Carrasco A Jr, Saltzman AF, Wilcox DT. Inpatient interventions that may preclude outpatient open pyeloplasty in infants. Int Braz J Urol. 2019 Jan-Feb;45(1):145-149. PubMed PMID: 30620155
Goodstein TA, Cost NG, Campbell JB, Vemulakonda V, Wilcox D, Saltzman AF. A Contemporary Analysis of Pediatric Urology Surgical Volume at a Tertiary Care Center. Urology. 2019 Mar;125:179-183. PubMed PMID: 30610906
Acker S, Peña A, Wilcox D, Alaniz V, Bischoff A. Transition of care: a growing concern in adult patients born with colorectal anomalies. Pediatr Surg Int. 2019 Feb;35(2):233-237. PubMed PMID: 30392127
Brodie K, Alaniz V, Buyers E, Caldwell B, Grantham E, Sheeder J, Wilcox D, Huguelet P. A Study of Adolescent Female Genitalia: What is Normal?. J Pediatr Adolesc Gynecol. 2019 Feb;32(1):27-31. PubMed PMID: 30244193
Hecht S, Hall J, Ketzer J, Walker J, Trecartin A, Wilcox D, Peña A, Bischoff A. Ectopic ureters in anorectal malformations. Pediatr Surg Int. 2019 Sep;35(9):1005-1008. PubMed PMID: 31278478
Bischoff A, Trecartin A, Alaniz V, Hecht S, Wilcox DT, Peña A. A cloacal anomaly is not a disorder of sex development. Pediatr Surg Int. 2019 Sep;35(9):985-987. PubMed PMID: 31256297
Bischoff A, Bealer J, Wilcox DT, Peña A. Error traps and culture of safety in anorectal malformations. Semin Pediatr Surg. 2019 Jun;28(3):131-134. PubMed PMID: 31171146
Iguchi N, Dönmez MI, Carrasco A Jr, Wilcox DT, Pineda RH, Malykhina AP, Cost NG. Doxorubicin induces detrusor smooth muscle impairments through myosin dysregulation, leading to a risk of lower urinary tract dysfunction. Am J Physiol Renal Physiol. 2019 Jul 1;317(1):F197-F206. PubMed PMID: 31066574
Danzig MR, Wild TT, Holbrook S, Wilcox DT. Distribution of a photographic atlas did not reduce postoperative care utilization after pediatric circumcision or the indispensability of the pediatric urology clinic nurse. J Pediatr Urol. 2019 May;15(3):227.e1-227.e6. PubMed PMID: 30940432
Dönmez MI, Carrasco A Jr, Saltzman AF, Wilcox DT. Inpatient interventions that may preclude outpatient open pyeloplasty in infants. Int Braz J Urol. 2019 Jan-Feb;45(1):145-149. PubMed PMID: 30620155
Goodstein TA, Cost NG, Campbell JB, Vemulakonda V, Wilcox D, Saltzman AF. A Contemporary Analysis of Pediatric Urology Surgical Volume at a Tertiary Care Center. Urology. 2019 Mar;125:179-183. PubMed PMID: 30610906
Acker S, Peña A, Wilcox D, Alaniz V, Bischoff A. Transition of care: a growing concern in adult patients born with colorectal anomalies. Pediatr Surg Int. 2019 Feb;35(2):233-237. PubMed PMID: 30392127
Brodie K, Alaniz V, Buyers E, Caldwell B, Grantham E, Sheeder J, Wilcox D, Huguelet P. A Study of Adolescent Female Genitalia: What is Normal?. J Pediatr Adolesc Gynecol. 2019 Feb;32(1):27-31. PubMed PMID: 30244193
Acker S, Peña A, Wilcox D, Alaniz V, Bischoff A. Transition of care: a growing concern in adult patients born with colorectal anomalies. Pediatr Surg Int. 2018 Nov 3. [Epub ahead of print] PubMed PMID: 30392127
Brodie K, Alaniz V, Buyers E, Caldwell B, Grantham E, Sheeder J, Wilcox D, Huguelet P. A Study of Adolescent Female Genitalia: What is Normal?. J Pediatr Adolesc Gynecol. 2018 Sep 20. [Epub ahead of print] PubMed PMID: 30244193
Iguchi N, Malykhina AP, Wilcox DT. Early life voiding dysfunction leads to lower urinary tract dysfunction through alteration of muscarinic and purinergic signaling in the bladder. Am J Physiol Renal Physiol. 2018 Aug 8. [Epub ahead of print] PubMed PMID: 30089034
Saltzman AF, Carrasco A Jr, Colvin A, Campbell JB, Vemulakonda VM, Wilcox D. Patients with disorders of sex development and proximal hypospadias are at high risk for reoperation. World J Urol. 2018 May 31. [Epub ahead of print] PubMed PMID: 29855697
Peña A, Bischoff A, Wilcox D. Letter to the editor. J Pediatr Surg. 2018 Aug;53(8):1639. PubMed PMID: 29793753
Rove KO, Brockel MA, Saltzman AF, Dönmez MI, Brodie KE, Chalmers DJ, Caldwell BT, Vemulakonda VM, Wilcox DT. Prospective study of enhanced recovery after surgery protocol in children undergoing reconstructive operations. J Pediatr Urol. 2018 Jun;14(3):252.e1-252.e9. PubMed PMID: 29398586
Iguchi N, Malykhina AP, Wilcox DT. Early life voiding dysfunction leads to lower urinary tract dysfunction through alteration of muscarinic and purinergic signaling in the bladder. Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1320-F1328. PubMed PMID: 30089034
Iguchi N, Malykhina AP, Wilcox DT. Early life voiding dysfunction leads to lower urinary tract dysfunction through alteration of muscarinic and purinergic signaling in the bladder. Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1320-F1328. PubMed PMID: 30089034
Saltzman AF, Carrasco A Jr, Colvin A, Campbell JB, Vemulakonda VM, Wilcox D. Patients with disorders of sex development and proximal hypospadias are at high risk for reoperation. World J Urol. 2018 Dec;36(12):2051-2058. PubMed PMID: 29855697
Peña A, Bischoff A, Wilcox D. Letter to the editor. J Pediatr Surg. 2018 Aug;53(8):1639. PubMed PMID: 29793753
Rove KO, Brockel MA, Saltzman AF, Dönmez MI, Brodie KE, Chalmers DJ, Caldwell BT, Vemulakonda VM, Wilcox DT. Prospective study of enhanced recovery after surgery protocol in children undergoing reconstructive operations. J Pediatr Urol. 2018 Jun;14(3):252.e1-252.e9. PubMed PMID: 29398586
Iguchi N, Dönmez MI, Malykhina AP, Carrasco A Jr, Wilcox DT. Preventative effects of a HIF inhibitor, 17-DMAG, on partial bladder outlet obstruction-induced bladder dysfunction. Am J Physiol Renal Physiol. 2017 Nov 1;313(5):F1149-F1160. PubMed PMID: 28768664
Caldwell BT, Wilcox DT, Cost NG. Current Management for Pediatric Urologic Oncology. Adv Pediatr. 2017 Aug;64(1):191-223. PubMed PMID: 28688589
Rove KO, Husmann DA, Wilcox DT, Vricella GJ, Higuchi TT. Systematic review of bladder cancer outcomes in patients with spina bifida. J Pediatr Urol. 2017 Oct;13(5):456.e1-456.e9. PubMed PMID: 28687411
Dönmez MI, Carrasco A Jr, Saltzman AF, Vemulakonda V, Wilcox DT. Long-term outcomes of cutaneous vesicostomy in patients with neuropathic bladder caused by spina bifida. J Pediatr Urol. 2017 Dec;13(6):622.e1-622.e4. PubMed PMID: 28669586
Malykhina AP, Brodie KE, Wilcox DT. Genitourinary and gastrointestinal co-morbidities in children: The role of neural circuits in regulation of visceral function. J Pediatr Urol. 2017 Apr;13(2):177-182. PubMed PMID: 28392009
Iguchi N, Dönmez MI, Malykhina AP, Carrasco A Jr, Wilcox DT. Preventative effects of a HIF inhibitor, 17-DMAG, on partial bladder outlet obstruction-induced bladder dysfunction. Am J Physiol Renal Physiol. 2017 Nov 1;313(5):F1149-F1160. PubMed PMID: 28768664
Caldwell BT, Wilcox DT, Cost NG. Current Management for Pediatric Urologic Oncology. Adv Pediatr. 2017 Aug;64(1):191-223. PubMed PMID: 28688589
Rove KO, Husmann DA, Wilcox DT, Vricella GJ, Higuchi TT. Systematic review of bladder cancer outcomes in patients with spina bifida. J Pediatr Urol. 2017 Oct;13(5):456.e1-456.e9. PubMed PMID: 28687411
Dönmez MI, Carrasco A Jr, Saltzman AF, Vemulakonda V, Wilcox DT. Long-term outcomes of cutaneous vesicostomy in patients with neuropathic bladder caused by spina bifida. J Pediatr Urol. 2017 Dec;13(6):622.e1-622.e4. PubMed PMID: 28669586
Malykhina AP, Brodie KE, Wilcox DT. Genitourinary and gastrointestinal co-morbidities in children: The role of neural circuits in regulation of visceral function. J Pediatr Urol. 2017 Apr;13(2):177-182. PubMed PMID: 28392009
Wilcox D. A potpourri of pediatric urology. J Pediatr Urol. 2016 Oct;12(5):319-320. PubMed PMID: 27969097
Cohen AJ, Brodie K, Murthy P, Wilcox DT, Gundeti MS. Comparative Outcomes and Perioperative Complications of Robotic Vs Open Cystoplasty and Complex Reconstructions. Urology. 2016 Nov;97:172-178. PubMed PMID: 27443464
Iguchi N, Malykhina AP, Wilcox DT. Inhibition of HIF Reduces Bladder Hypertrophy and Improves Bladder Function in Murine Model of Partial Bladder Outlet Obstruction. J Urol. 2016 Apr;195(4 Pt 2):1250-6. PubMed PMID: 26926557
Brodie KE, Grantham EC, Huguelet PS, Caldwell BT, Westfall NJ, Wilcox DT. Study of clitoral hood anatomy in the pediatric population. J Pediatr Urol. 2016 Jun;12(3):177.e1-5. PubMed PMID: 26851151
Wilcox D. A potpourri of pediatric urology. J Pediatr Urol. 2016 Oct;12(5):319-320. PubMed PMID: 27969097
Cohen AJ, Brodie K, Murthy P, Wilcox DT, Gundeti MS. Comparative Outcomes and Perioperative Complications of Robotic Vs Open Cystoplasty and Complex Reconstructions. Urology. 2016 Nov;97:172-178. PubMed PMID: 27443464
Iguchi N, Malykhina AP, Wilcox DT. Inhibition of HIF Reduces Bladder Hypertrophy and Improves Bladder Function in Murine Model of Partial Bladder Outlet Obstruction. J Urol. 2016 Apr;195(4 Pt 2):1250-6. PubMed PMID: 26926557
Brodie KE, Grantham EC, Huguelet PS, Caldwell BT, Westfall NJ, Wilcox DT. Study of clitoral hood anatomy in the pediatric population. J Pediatr Urol. 2016 Jun;12(3):177.e1-5. PubMed PMID: 26851151
Vemulakonda VM, Wilcox DT, Torok MR, Hou A, Campbell JB, Kempe A. Inter-rater reliability of postnatal ultrasound interpretation in infants with congenital hydronephrosis. Int Urol Nephrol. 2015 Sep;47(9):1457-61. PubMed PMID: 26253827
Chalmers DJ, Rove KO, Wiedel CA, Tong S, Siparsky GL, Wilcox DT. Clean intermittent catheterization as an initial management strategy provides for adequate preservation of renal function in newborns with persistent cloaca. J Pediatr Urol. 2015 Aug;11(4):211.e1-4. PubMed PMID: 26187141
Vemulakonda VM, Wilcox DT, Crombleholme TM, Bronsert M, Kempe A. Factors associated with age at pyeloplasty in children with ureteropelvic junction obstruction. Pediatr Surg Int. 2015 Sep;31(9):871-7. PubMed PMID: 26143412
Chalmers DJ, Bielsky A, Wild TT, Siparsky GL, Wilcox DT. Continuous local anesthetic infusion for children with spina bifida undergoing major reconstruction of the lower urinary tract. J Pediatr Urol. 2015 Apr;11(2):72.e1-5. PubMed PMID: 25819374
Chalmers DJ, Siparsky GL, Wiedel CA, Wilcox DT. Distal hypospadias repair in infants without a postoperative stent. Pediatr Surg Int. 2015 Mar;31(3):287-90. PubMed PMID: 25475503
Pohlman GD, Phillips JM, Wilcox DT. Simple method of paraphimosis reduction revisited: point of technique and review of the literature. J Pediatr Urol. 2013 Feb;9(1):104-7. PubMed PMID: 22827972