Carlyne Cool, MD

Publications

• Wick MJ, Buesing EJ, Wehling CA, Loomis ZL, Cool CD, Zamora MR, Miller YE, Colgan SP, Hersh LB, Voelkel NF, Dempsey EC. Decreased neprilysin and pulmonary vascular remodeling in chronic obstructive pulmonary disease. AJRCCM. 183(3):330-340, 2011 Feb.1.
• Cool CD, Voelkel NF, Bull T. Viral infection and pulmonary hypertension: is there an association? Expert Review of Respiratory Medicine. 5(2):207-16, 2011 Apr.
• Yasuo M, Mizuno S, Kraskauskas D, Bogaard HJ, Natarajan R, Cool CD, Zamora M, Voelkel NF. Hypoxia-inducible factor-1alpha in human emphysema lung tissue. European Respiratory Journal. 37(4):775-83, 2011 Apr.
• Stacher E, Graham BB, Hunt J, Gandjeva A, Groshong SD, McLaughlin VV, Jessup M, Grizzle WE, Aldred MA, Cool CD, Tuder RM. Modern age of pathology of pulmonary arterial hypertension. Am J Resp & Crit Care Med 186(3):261-272, 2012 Aug 1.
• Mizuno S, Bogaard HJ, Gomez-Arroyo J, Alhussaini A, Kraskauskas D, Cool CD, Voelkel NF. MicroRNA-199A-5p is associated with hypoxia-inducible factor-1 expression in lungs from patients with COPD. Chest 142(3):663-72, 2012 Sep.
• Leslie KO, Cool CD, Sporn TA, Curran-Everett D, Steele MP, Brown KK, Wahidi MM, Schwartz DA. Familial idiopathic interstitial pneumonia: histopathology and survival in 30 patients. Archives of Pathology & Laboratory Medicine 136(11):1366-76, 2012 Nov
• Mizuno S, Farkas L, al Husseini A, Farkas D, Gomez-Arroyo J, Kraskauskas D, Nicolls MR, Cool CD, Bogaard HJ, Voelkel NF. Severe pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization. American Journal of Respiratory Cell & Molecular Biology. 47(5):679-87, 2012 Nov
• Farkas D, Kraskauskas D, Drake JI, Alhussaini AA, Kraskauskiene V, Bogaard HJ, Cool CD, Voelkel NF, Farkas L. CXCR4 inhibition ameliorates severe obliterative pulmonary hypertension and accumulation of C-kit( ) cells in rats. PLoS One. 2014;9(2):e89810. PubMed PMID: 24587052
• Nold-Petry CA, Rudloff I, Baumer Y, Ruvo M, Marasco D, Botti P, Farkas L, Cho SX, Zepp JA, Azam T, Dinkel H, Palmer BE, Boisvert WA, Cool CD, Taraseviciene-Stewart L, Heinhuis B, Joosten LA, Dinarello CA, Voelkel NF, Nold MF. IL-32 promotes angiogenesis. J Immunol. 2014 Jan 15;192(2):589-602. PubMed PMID: 24337385
• Anathy V, Aesif SW, Hoffman SM, Bement JL, Guala AS, Lahue KG, Leclair LW, Suratt BT, Cool CD, Wargo MJ, Janssen-Heininger YM. Glutaredoxin-1 Attenuates S-Glutathionylation of the Death Receptor Fas and Decreases Resolution of Pseudomonas aeruginosa Pneumonia. Am J Respir Crit Care Med. 2014 Feb 15;189(4):463-74. PubMed PMID: 24325366
• Solomon JJ, Ryu JH, Tazelaar HD, Myers JL, Tuder R, Cool CD, Curran-Everett D, Fischer A, Swigris JJ, Brown KK. Fibrosing interstitial pneumonia predicts survival in patients with rheumatoid arthritis-associated interstitial lung disease (RA-ILD). Respir Med. 2013 Aug;107(8):1247-52. PubMed PMID: 23791462
• Yang IV, Coldren CD, Leach SM, Seibold MA, Murphy E, Lin J, Rosen R, Neidermyer AJ, McKean DF, Groshong SD, Cool C, Cosgrove GP, Lynch DA, Brown KK, Schwarz MI, Fingerlin TE, Schwartz DA. Expression of cilium-associated genes defines novel molecular subtypes of idiopathic pulmonary fibrosis. Thorax. 2013 Dec;68(12):1114-21. PubMed PMID: 23783374
• Horita H, Furgeson SB, Ostriker A, Olszewski KA, Sullivan T, Villegas LR, Levine M, Parr JE, Cool CD, Nemenoff RA, Weiser-Evans MC. Selective inactivation of PTEN in smooth muscle cells synergizes with hypoxia to induce severe pulmonary hypertension. J Am Heart Assoc. 2013 May 31;2(3):e000188. PubMed PMID: 23727701
• Kratzer A, Chu HW, Salys J, Moumen Z, Leberl M, Bowler R, Cool C, Zamora M, Taraseviciene-Stewart L. Endothelial cell adhesion molecule CD146: implications for its role in the pathogenesis of COPD. J Pathol. 2013 Aug;230(4):388-98. PubMed PMID: 23649916
• Kratzer A, Salys J, Nold-Petry C, Cool C, Zamora M, Bowler R, Koczulla AR, Janciauskiene S, Edwards MG, Dinarello CA, Taraseviciene-Stewart L. Role of IL-18 in second-hand smoke-induced emphysema. Am J Respir Cell Mol Biol. 2013 Jun;48(6):725-32. PubMed PMID: 23392573
• Chung JH, Chawla A, Peljto AL, Cool C, Groshong SD, Talbert JL, McKean D, Brown KK, Fingerlin TE, Schwarz MI, Schwartz DA, Lynch DA. CT findings of probable UIP have a high predictive value for histologic UIP. Chest. 2014 Oct 9. [Epub ahead of print] PubMed PMID: 25317858
• Browning ET, Huckleberry JM, Barrow WB, Restauri NL, Kemme DJ, Cool CD, Weyant MJ, Franklin WA, Camidge DR. Downstaging of Non-Small-Cell Lung Cancer Through Identification of Reversible Drug Toxicity. J Clin Oncol. 2014 May 5. [Epub ahead of print] PubMed PMID: 24799494
• Farkas D, Alhussaini AA, Kraskauskas D, Kraskauskiene V, Cool CD, Nicolls MR, Natarajan R, Farkas L. Nuclear factor ?B inhibition reduces lung vascular lumen obliteration in severe pulmonary hypertension in rats. Am J Respir Cell Mol Biol. 2014 Sep;51(3):413-25. PubMed PMID: 24684441
• Farkas D, Kraskauskas D, Drake JI, Alhussaini AA, Kraskauskiene V, Bogaard HJ, Cool CD, Voelkel NF, Farkas L. CXCR4 inhibition ameliorates severe obliterative pulmonary hypertension and accumulation of C-kit? cells in rats. PLoS One. 2014;9(2):e89810. PubMed PMID: 24587052
• Nold-Petry CA, Rudloff I, Baumer Y, Ruvo M, Marasco D, Botti P, Farkas L, Cho SX, Zepp JA, Azam T, Dinkel H, Palmer BE, Boisvert WA, Cool CD, Taraseviciene-Stewart L, Heinhuis B, Joosten LA, Dinarello CA, Voelkel NF, Nold MF. IL-32 promotes angiogenesis. J Immunol. 2014 Jan 15;192(2):589-602. PubMed PMID: 24337385
• Anathy V, Aesif SW, Hoffman SM, Bement JL, Guala AS, Lahue KG, Leclair LW, Suratt BT, Cool CD, Wargo MJ, Janssen-Heininger YM. Glutaredoxin-1 attenuates S-glutathionylation of the death receptor fas and decreases resolution of Pseudomonas aeruginosa pneumonia. Am J Respir Crit Care Med. 2014 Feb 15;189(4):463-74. PubMed PMID: 24325366
• Steele MP, Luna LG, Coldren CD, Murphy E, Hennessy CE, Heinz D, Evans CM, Groshong S, Cool C, Cosgrove GP, Brown KK, Fingerlin TE, Schwarz MI, Schwartz DA, Yang IV. Relationship between gene expression and lung function in Idiopathic Interstitial Pneumonias. BMC Genomics. 2015 Oct 26;16(1):869. PubMed PMID: 26503507
• Bikkavilli RK, Avasarala S, Van Scoyk M, Arcaroli J, Brzezinski C, Zhang W, Edwards MG, Rathinam MK, Zhou T, Tauler J, Borowicz S, Lussier YA, Parr BA, Cool CD, Winn RA. Wnt7a is a novel inducer of ß-catenin-independent tumor-suppressive cellular senescence in lung cancer. Oncogene. 2015 Oct 16;34(42):5406. PubMed PMID: 26473947
• Bikkavilli RK, Avasarala S, Van Scoyk M, Arcaroli J, Brzezinski C, Zhang W, Edwards MG, Rathinam MK, Zhou T, Tauler J, Borowicz S, Lussier YA, Parr BA, Cool CD, Winn RA. Wnt7a is a novel inducer of ß-catenin-independent tumor-suppressive cellular senescence in lung cancer. Oncogene. 2015 Oct 16;34(42):5317-28. PubMed PMID: 25728679
• Diebel KW, Oko LM, Medina EM, Niemeyer BF, Warren CJ, Claypool DJ, Tibbetts SA, Cool CD, Clambey ET, van Dyk LF. Gammaherpesvirus small noncoding RNAs are bifunctional elements that regulate infection and contribute to virulence in vivo. MBio. 2015 Feb 17;6(1):e01670-14. PubMed PMID: 25691585
• Chung JH, Chawla A, Peljto AL, Cool CD, Groshong SD, Talbert JL, McKean DF, Brown KK, Fingerlin TE, Schwarz MI, Schwartz DA, Lynch DA. CT scan findings of probable usual interstitial pneumonitis have a high predictive value for histologic usual interstitial pneumonitis. Chest. 2015 Feb;147(2):450-9. PubMed PMID: 25317858
• Galambos C, Sims-Lucas S, Abman SH, Cool CD. Intrapulmonary Bronchopulmonary Anastomoses and Plexiform Lesions in Idiopathic Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2016 Mar 1;193(5):574-6. PubMed PMID: 26930433
• Browning ET, Huckleberry JM, Barrow WB, Restauri NL, Kemme DJ, Cool CD, Weyant MJ, Franklin WA, Camidge DR. Downstaging of Non-Small-Cell Lung Cancer Through Identification of Reversible Drug Toxicity. J Clin Oncol. 2016 Jan 10;34(2):e6-8. PubMed PMID: 24799494
• Niemeyer BF, Oko LM, Medina EM, Oldenburg DG, White DW, Cool CD, Clambey ET, van Dyk LF. Host Tumor Suppressor p18(INK4c) functions as a potent cell-intrinsic inhibitor of ?HV68 reactivation and pathogenesis. J Virol. 2018 Jan 3. [Epub ahead of print] PubMed PMID: 29298882
• Ramakrishnan VR, Gonzalez JR, Cooper SE, Barham HP, Anderson CB, Larson ED, Cool CD, Diller JD, Jones K, Kinnamon SC. RNA sequencing and pathway analysis identify tumor necrosis factor alpha driven small proline-rich protein dysregulation in chronic rhinosinusitis. Am J Rhinol Allergy. 2017 Sep 1;31(5):283-288. PubMed PMID: 28859701
• Mizuno S, Ishizaki T, Kadowaki M, Akai M, Shiozaki K, Iguchi M, Oikawa T, Nakagawa K, Osanai K, Toga H, Gomez-Arroyo J, Kraskauskas D, Cool CD, Bogaard HJ, Voelkel NF. p53 Signaling Pathway Polymorphisms Associated With Emphysematous Changes in Patients With COPD. Chest. 2017 Jul;152(1):58-69. PubMed PMID: 28315337
• Bikkavilli RK, Zerayesus SA, Van Scoyk M, Wilson L, Wu PY, Baskaran A, Tang K, Raheem S, Samuelson BA, Reddy NM, Reddy SP, Cool CD, Kosmider B, Avasarala S, Winn RA. K-homology splicing regulatory protein (KSRP) promotes post-transcriptional destabilization of Spry4 transcripts in non-small cell lung cancer. J Biol Chem. 2017 May 5;292(18):7423-7434. PubMed PMID: 28275056
• Farkas D, Thompson AAR, Bhagwani AR, Hultman S, Ji H, Kotha N, Farr G, Arnold ND, Braithwaite A, Casbolt H, Cole JE, Sabroe I, Monaco C, Cool CD, Goncharova EA, Lawrie A, Farkas L. Toll-like Receptor 3 Is a Therapeutic Target for Pulmonary Hypertension. Am J Respir Crit Care Med. 2019 Jan 15;199(2):199-210. PubMed PMID: 30211629
• Choi SH, Wallace AM, Schneider DA, Burg E, Kim J, Alekseeva E, Ubags ND, Cool CD, Fang L, Suratt BT, Miller YI. AIBP augments cholesterol efflux from alveolar macrophages to surfactant and reduces acute lung inflammation. JCI Insight. 2018 Aug 23;3(16). [Epub ahead of print] PubMed PMID: 30135304
• Bamberg A, Redente EF, Groshong SD, Tuder RM, Cool CD, Keith RC, Edelman BL, Black BP, Cosgrove GP, Wynes MW, Curran-Everett D, De Langhe S, Ortiz LA, Thorburn A, Riches DWH. Protein Tyrosine Phosphatase-N13 Promotes Myofibroblast Resistance to Apoptosis in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2018 Oct 1;198(7):914-927. PubMed PMID: 29727583
• Okamoto T, Mathai SK, Hennessy CE, Hancock LA, Walts AD, Stefanski AL, Brown KK, Lynch DA, Cosgrove GP, Groshong SD, Cool CD, Schwarz MI, Banda NK, Thurman JM, Yang IV, Holers VM, Schwartz DA. The relationship between complement C3 expression and the MUC5B genotype in pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2018 Jul 1;315(1):L1-L10. PubMed PMID: 29565179
• Krefft SD, Cool CD, Rose CS. The emerging spectrum of exposure-related bronchiolitis. Curr Opin Allergy Clin Immunol. 2018 Apr;18(2):87-95. PubMed PMID: 29394172
• Niemeyer BF, Oko LM, Medina EM, Oldenburg DG, White DW, Cool CD, Clambey ET, van Dyk LF. Host Tumor Suppressor p18(INK4c) Functions as a Potent Cell-Intrinsic Inhibitor of Murine Gammaherpesvirus 68 Reactivation and Pathogenesis. J Virol. 2018 Mar 15;92(6). PubMed PMID: 29298882
• Bhagwani AR, Farkas D, Harmon B, Authelet KJ, Cool CD, Kolb M, Goncharova E, Yoder MC, Clauss M, Freishtat R, Farkas L. Clonally selected primitive endothelial cells promote occlusive pulmonary arteriopathy and severe pulmonary hypertension in rats exposed to chronic hypoxia. Sci Rep. 2020 Jan 24;10(1):1136. PubMed PMID: 31980720
• Solomon JJ, Matson S, Kelmenson LB, Chung JH, Hobbs SB, Rosas IO, Dellaripa PF, Doyle TJ, Poli S, Esposito AJ, Visser A, Marin AI, Amigues I, Fernández Pérez ER, Brown KK, Mahler M, Heinz D, Cool C, Deane KD, Swigris JJ, Demoruelle MK. IgA Antibodies Directed Against Citrullinated Protein Antigens Are Elevated in Patients With Idiopathic Pulmonary Fibrosis. Chest. 2019 Dec 23. [Epub ahead of print] PubMed PMID: 31877269
• Kurche JS, Dobrinskikh E, Hennessy CE, Huber J, Estrella A, Hancock LA, Schwarz MI, Okamoto T, Cool CD, Yang IV, Evans CM, Schwartz DA. Muc5b Enhances Murine Honeycomb-like Cyst Formation. Am J Respir Cell Mol Biol. 2019 Oct;61(4):544-546. PubMed PMID: 31573335
• He C, Lee JS, Cool CD, Wicklund MP, Fischer A. Development of Autoimmune Interstitial Lung Disease in a Patient with Inclusion Body Myositis. Am J Med. 2019 Dec;132(12):e854-e855. PubMed PMID: 31310746
• Tuder RM, Cool CD. Pulmonary Arteries and Microcirculation in COPD With Pulmonary Hypertension: Bystander or Culprit?. Chest. 2019 Jul;156(1):4-6. PubMed PMID: 31279376
• Bhagwani AR, Hultman S, Farkas D, Moncayo R, Dandamudi K, Zadu AK, Cool CD, Farkas L. Endothelial cells are a source of Nestin expression in Pulmonary Arterial Hypertension. PLoS One. 2019;14(3):e0213890. PubMed PMID: 30883593
• Farkas D, Thompson AAR, Bhagwani AR, Hultman S, Ji H, Kotha N, Farr G, Arnold ND, Braithwaite A, Casbolt H, Cole JE, Sabroe I, Monaco C, Cool CD, Goncharova EA, Lawrie A, Farkas L. Toll-like Receptor 3 Is a Therapeutic Target for Pulmonary Hypertension. Am J Respir Crit Care Med. 2019 Jan 15;199(2):199-210. PubMed PMID: 30211629
• 150. Cool, C. D., Kuebler, W. M., Bogaard, H. J., Spiekerkoetter, E., Nicolls, M. R., Voelkel, N. F. (2020). The hallmarks of severe pulmonary arterial hypertension: the cancer hypothesis-ten years later. American Journal of Physiology - Lung Cellular & Molecular Physiology, 318, L1115-L1130. https://dx.doi.org/10.1152/ajplung.00476.2019
• 151. Lee MH, Cool CD, Maloney JP. Histopathological Correlation of Acute on Chronic Eosinophilic Pneumonitis Caused by Vaporized Cannabis Oil Inhalation. Chest. 2021;159(3):e137-e139. doi:10.1016/j.chest.2020.10.016, 10.1016/j.chest.2020.10.016
• 152. Verbsky, J. W., Hintermeyer, M. K., Simpson, P. M., Feng, M., Barbeau, J., Rao, N., Cool, C. D., Sosa-Lozano, L. A., Baruah, D., Hammelev, E., Busalacchi, A., Rymaszewski, A., Woodliff, J., Chen, S., Bausch-Jurken, M., Routes, J. M. (2021). Rituximab and antimetabolite treatment of granulomatous and lymphocytic interstitial lung disease in common variable immunodeficiency. Journal of Allergy & Clinical Immunology, 147, 704-712.e17. https://dx.doi.org/10.1016/j.jaci.2020.07.021
• Rose CS, Moore CM, Zell-Baran LM, Krefft S, Wolff J, Pang K, Parr J, Cool C. Small airways and airspace inflammation and injury distinguish lung histopathology in deployed military personnel from healthy and diseased lungs. Hum Pathol. 2022 Jun;124:56-66. doi: 10.1016/j.humpath.2022.02.014. Epub 2022 Feb 28. PMID: 35240130.
• 153. Sanchez, F., Gutierrez, J. M., Kha, L. C., Jimenez-Juan, L., Cool, C., Vargas, D., Oikonomou, A. (2021). Pathological entities that may affect the lungs and the myocardium. evaluation with chest ct and cardiac mr. Clinical Imaging, 70, 124-135. https://dx.doi.org/10.1016/j.clinimag.2020.10.038
• Cohen, RA, Rose, CS, Go LH, Zell-Baran LM, Almberg KS, Sarver EA, Lowers HA, Iwaniuk C, Clingerman SM, Richardson DL, Abraham JL, Cool CD, Franko AD, Hubbs AF, Murray J, Orandie MS, Sanyal S, Vorajee NI, Petsonk EL, Zulfikar R, Green FHY. Pathology and mineralogy demonstrate respirable crystalline silica is a major cause of severe pneumoconiosis in U.S. coal miners. Ann Am Thorac Soc Vol 19, No 9, pp 1469–1478, Sep 2022.
• Blanchard N, Link P, Farkas D, Harmon B, Hudson J, Bogamuwa S, Piper B, Authelet K, Cool C, Heise R, Freishtat R, Farkas L. Dichotomous role of integrin-ß5 in endothelial cells. Pulmonary Circulation. Nov 2022 Accepted
• 154. Furusawa, H., Cardwell, J. H., Okamoto, T., Walts, A. D., Konigsberg, I. R., Kurche, J. S., Bang, T. J., Schwarz, M. I., Brown, K. K., Kropski, J. A., Rojas, M., Cool, C. D., Lee, J. S., Wolters, P. J., Yang, I. V., Schwartz, D. A. (2020). Chronic hypersensitivity pneumonitis, an interstitial lung disease with distinct molecular signatures. American Journal of Respiratory & Critical Care Medicine, 202, 1430-1444. https://dx.doi.org/10.1164/rccm.202001-0134OC
• Blumhagen RZ, Kurche JS, Cool CD, Walts AD, Heinz D, Fingerlin TE, Yang IV, Schwartz DA. Spatially distinct molecular patterns of gene expression in idiopathic pulmonary fibrosis. Respir Res. 2023 Nov 17;24(1):287. PubMed PMID: 37978501
• Cool CD, Murray J, Vorajee NI, Rose CS, Zell-Baran LM, Sanyal S, Franko AD, Almberg KS, Iwaniuk C, Go LHT, Green FHY, Cohen RA. Pathologic Findings in Severe Coal Workers' Pneumoconiosis in Contemporary US Coal Miners. Arch Pathol Lab Med. 2023 Oct 18. [Epub ahead of print] PubMed PMID: 37852172
• Yun JH, Khan MAW, Ghosh A, Hobbs BD, Castaldi PJ, Hersh CP, Miller PG, Cool CD, Sciurba F, Barwick L, Limper AH, Flaherty K, Criner GJ, Brown K, Wise R, Martinez F, Silverman EK, DeMeo D, Cho MH, Bick AG. Clonal Somatic Mutations in Chronic Lung Diseases Are Associated with Reduced Lung Function. Am J Respir Crit Care Med. 2023 Dec 1;208(11):1196-1205. PubMed PMID: 37788444
• Rose CS, Zell-Baran LM, Cool C, Moore CM, Wolff J, Oh AS, Koelsch T, Richards JC, Krefft SD, Wilson CG, Lynch DA. Findings on High Resolution Computed Tomography in Symptomatic Veterans with Deployment-Related Lung Disease. J Thorac Imaging. 2023 Sep 15. [Epub ahead of print] PubMed PMID: 37732711
• Dawrs SN, Virdi R, Islam MN, Hasan NA, Norton GJ, Crooks JL, Parr J, Heinz D, Cool CD, Belisle JT, Chan ED, Honda JR. Immunological and metabolic characterization of environmental Mycobacterium chimaera infection in a murine model. Microbes Infect. 2023 Nov-Dec;25(8):105184. PubMed PMID: 37453489
• Go LHT, Rose CS, Zell-Baran LM, Almberg KS, Iwaniuk C, Clingerman S, Richardson DL, Abraham JL, Cool CD, Franko AD, Green FHY, Hubbs AF, Murray J, Orandle MS, Sanyal S, Vorajee NI, Sarver EA, Petsonk EL, Cohen RA. Historical shift in pathological type of progressive massive fibrosis among coal miners in the USA. Occup Environ Med. 2023 Aug;80(8):425-430. PubMed PMID: 37295943
• Hua JT, Cool CD, Lowers HA, Go LHT, Zell-Baran LM, Sarver EA, Almberg KS, Pang KD, Majka SM, Franko AD, Vorajee NI, Cohen RA, Rose CS. Characterizing Lung Particulates Using Quantitative Microscopy in Coal Miners With Severe Pneumoconiosis. Arch Pathol Lab Med. 2023 Jun 1. [Epub ahead of print] PubMed PMID: 37270802
• Koslow M, Lynch DA, Cool CD, Groshong SD, Downey GP. Lymphangioleiomyomatosis and Other Cystic Lung Diseases. Immunol Allergy Clin North Am. 2023 May;43(2):359-377. PubMed PMID: 37055093
• Hua JT, Cool CD, Green FHY. Pathology and Mineralogy of the Pneumoconioses. Semin Respir Crit Care Med. 2023 Jun;44(3):327-339. PubMed PMID: 36972614
• Zell-Baran LM, Go LHT, Sarver E, Almberg KS, Iwaniuk C, Green FHY, Abraham JL, Cool C, Franko A, Hubbs AF, Murray J, Orandle MS, Sanyal S, Vorajee N, Cohen RA, Rose CS. Mining Tenure and Job Duties Differ Among Contemporary and Historic Underground Coal Miners With Progressive Massive Fibrosis. J Occup Environ Med. 2023 Apr 1;65(4):315-320. PubMed PMID: 36730599
• Blanchard N, Link PA, Farkas D, Harmon B, Hudson J, Bogamuwa S, Piper B, Authelet K, Cool CD, Heise RL, Freishtat R, Farkas L. Dichotomous role of integrin-ß5 in lung endothelial cells. Pulm Circ. 2022 Oct;12(4):e12156. PubMed PMID: 36438452
• Smirnova NF, Riemondy K, Bueno M, Collins S, Suresh P, Wang X, Patel KN, Cool C, Königshoff M, Sharma NS, Eickelberg O. Single-cell transcriptome mapping identifies a local, innate B cell population driving chronic rejection after lung transplantation. JCI Insight. 2022 Sep 22;7(18). PubMed PMID: 36134664
• Schenkel AR, Mitchell JD, Cool CD, Bai X, Groshong S, Koelsch T, Verma D, Ordway D, Chan ED. Characterization of Immune Cells From the Lungs of Patients With Chronic Non-Tuberculous Mycobacteria or Pseudomonas aeruginosa Infection. Immune Netw. 2022 Jun;22(3):e27. PubMed PMID: 35799709
• Cohen RA, Rose CS, Go LHT, Zell-Baran LM, Almberg KS, Sarver EA, Lowers HA, Iwaniuk C, Clingerman SM, Richardson DL, Abraham JL, Cool CD, Franko AD, Hubbs AF, Murray J, Orandle MS, Sanyal S, Vorajee NI, Petsonk EL, Zulfikar R, Green FHY. Pathology and Mineralogy Demonstrate Respirable Crystalline Silica Is a Major Cause of Severe Pneumoconiosis in U.S. Coal Miners. Ann Am Thorac Soc. 2022 Sep;19(9):1469-1478. PubMed PMID: 35353671
• Terella AM, Mariner P, Cool CD, Ramakrishnan VR. Use of a novel chinchilla skull base repair model to test a photo-initiated thiol-ene biopolymer. Int Forum Allergy Rhinol. 2022 Oct;12(10):1317-1320. PubMed PMID: 35344275
• Rose CS, Moore CM, Zell-Baran LM, Krefft S, Wolff J, Pang K, Parr J, Cool C. Small airways and airspace inflammation and injury distinguish lung histopathology in deployed military personnel from healthy and diseased lungs. Hum Pathol. 2022 Jun;124:56-66. PubMed PMID: 35240130

Professional Memberships

• College of American Pathologists, Member
• Colorado Society of Clinical Pathologists, Member
• Academy of Clinical Laboratory Physicians and Scientists, Associate Member

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

UCHealth Longs Peak Hospital
1750 E. Ken Pratt Boulevard
Longmont, CO 80504
720-718-7000

Hospital Affiliation

• University of Colorado Hospital
• National Jewish Health
• Veterans Affairs Medical Center

Specialty Information

Specialties

• Anatomic and Clinical, Board Certification (1998)
• Pathology, Board Certification
• Anatomic, Board Certification

Conditions & Treatments

• Lungs and Breathing - Interstitial Lung Disease
• Lungs and Breathing - Granulomatous Lung Disease
• Lungs and Breathing - Lung Disease
• Lungs and Breathing