Margaret E. Wierman, MD

Professional Titles

• Director Pituitary Program UCD, Chief of Endocrinology, Denver VAMC

Publications

• 1. Wierman ME, Basson R, Davis SR, Khosla S, Miller K, Rosner W, Santoro N: Clinical practice guideline: The therapeutic use of androgens in women: an Endocrine Society clinical practice guideline. Journal of Clinical Endocrinology and Metabolism 2006 91:3697-3716.
• 2. Cary LS, Xu M, Ertel J, Kleinschmidt-DeMasters BK, Lillehei K, Matsuoka I, Nielsen-Preiss S, Wierman ME. Bone Morphogenetic protein and retinoic acid inducible neural specific protein-3 (BRINP3) is expressed in gonadotrope cell pituitary adenomas and induces proliferation, migration and invasion gonadotropinomas. Endocrinology 2007 Mar;148(3):967-75. Epub 2006 Nov 30.
• 3. Allen MP, Nielson-Preiss SM, Xu M, Linseman DA, Pawlowski JE, Bouchard R, Heidenreich KA, Wierman ME. Adhesion Related Kinase Induction of Migration Requires PI3-kinase and Ras Stimulation of Rac Activity in immortalized GnRH neuronal cells. Endocrinology. 2007 E Mar 1
• 4. Wierman ME: Sex steroid effects at target tissues: mechanisms of action. Adv Physiol Educ. 2007 Mar;31(1):26-33.
• 5. Rothman MS, Arciniegas DB, Filley CM and Wierman ME: The neuroendocrine effects of traumatic brain injury. (in press, J Neuropyschiatry and Clnical Neurosciences, 2007).
• 6. Rothman MS and Wierman ME: Testosterone and Cardiovascular Disease in Men. In press, Aging Health 2007
• 7. Schwarting G, Wierman ME and Tobet S: GnRH Neuronal Migration, in press 2007
• 8. Wierman ME: Tissue Specific Effects of Sex Steroids: Additional Insights into the Women’s Health Initiative (WHI). In review Journal of Gynecologic Investigation, 2007.
• Ho PM, Barón AE, Wierman ME. Deaths and cardiovascular events in men receiving testosterone--reply. JAMA. 2014 Mar 5;311(9):964-5. PubMed PMID: 24595788
• Salian-Mehta S, Xu M, Knox A, Plummer L, Slavov D, Taylor M, Bevers S, Hodges R, Crowley W Jr, Wierman M. Functional Consequences of AXL Sequence Variants in Idiopathic Hypogonadotropic Hypogonadism. J Clin Endocrinol Metab. 2014 Jan 29;:jc20133426. [Epub ahead of print] PubMed PMID: 24476074
• 9. Rothman MS, Wierman ME: Physiologic and pathologic processes in GnRH. Current Opinion in Endocrinology and Diabetes, in review 2007.
• Vigen R, O'Donnell CI, Barón AE, Grunwald GK, Maddox TM, Bradley SM, Barqawi A, Woning G, Wierman ME, Plomondon ME, Rumsfeld JS, Ho PM. Association of testosterone therapy with mortality, myocardial infarction, and stroke in men with low testosterone levels. JAMA. 2013 Nov 6;310(17):1829-36. PubMed PMID: 24193080
• Cary LS, Xu M, Ertel J, Kleinschmidt-DeMasters BK, Lillehei K, Matsuoka I, Nielsen-Preiss S, Wierman ME. Bone Morphogenetic protein and retinoic acid inducible neural specific protein-3 (BRINP3) is expressed in gonadotrope cell pituitary adenomas and induces proliferation, migration and invasion gonadotropinomas. Endocrinology 2007 Mar;148(3):967-75. Epub 2006 Nov 30
• Allen MP, Nielson-Preiss SM, Xu M, Linseman DA, Pawlowski JE, Bouchard R, Heidenreich KA, Wierman ME. Adhesion Related Kinase Induction of Migration Requires PI3-kinase and Ras Stimulation of Rac Activity in immortalized GnRH neuronal cells. Endocrinology. 2007;148:2806-14
• Salian-Mehta S, Xu M, Wierman ME. AXL and MET crosstalk to promote gonadotropin releasing hormone (GnRH) neuronal cell migration and survival. Mol Cell Endocrinol. 2013 Jul 15;374(1-2):92-100. PubMed PMID: 23648337
• Wierman ME: Sex steroid effects at target tissues: mechanisms of action. Adv Physiol Educ. 2007;31:26-33.
• Weickhardt AJ, Doebele RC, Purcell WT, Bunn PA, Oton AB, Rothman MS, Wierman ME, Mok T, Popat S, Bauman J, Nieva J, Novello S, Ou SH, Camidge DR. Symptomatic reduction in free testosterone levels secondary to crizotinib use in male cancer patients. Cancer. 2013 Jul 1;119(13):2383-90. PubMed PMID: 23585220
• Rothman MS, Arciniegas DB, Filley CM and Wierman ME: The neuroendocrine effects of traumatic brain injury. J Neuropyschiatry and Clinical Neurosciences. 2007;19:363-72..
• Schwarting G, Wierman ME and Tobet S: GnRH Neuronal Migration. 2007;25:305-12.
• Rosner W, Hankinson SE, Sluss PM, Vesper HW, Wierman ME. Challenges to the measurement of estradiol: an endocrine society position statement. J Clin Endocrinol Metab. 2013 Apr;98(4):1376-87. PubMed PMID: 23463657
• Wierman ME and Kohrt WM: Vascular and metabolic effects of sex steroids: new insights into clinical trials. Reprod Med 2007 25:305-12.
• Rothman MS, Wierman ME: The role of GnRH in normal and pathologic endocrine processes. Current Opinion in Endocrinology and Diabetes. 2007; 14: 306-10.
• Wierman M, Basson R, Davis S, Khosla S, Miller K, Rosner W, Santoro N: Are the endocrine society’s clinical practice guidelines on androgen therapy in women misguided? A commentary-response. J Sex Med 2007 4:1782-83.
• Rothman MS and Wierman ME: Testosterone and Cardiovascular Disease in Men. In press, Aging Health 2007.
• Rothman MS and Wierman ME: Female Hypogonadism: Evaluation of the Hypothalamic-Pituitary-Ovarian Axis. Pituitary 2008 11:163-9.
• Pierce AM, Bliesner B , Xu M, Nielsen-Preiss S, Lemke G, Tobet S and Wierman ME: Axl and Tyro3 Modulate Female Reproduction by Influencing Gonadotropin Releasing Hormone (GnRH) Neuron Survival and Migration. Molecular Endocrinology 2008 22:2481-95.
• Mehta SM, Knox AJ, Xu M, Plummer L,Slavov D, Taylor M, Bevers S, Hodges RS, Crowley WF Jr,. Wierman ME. AXL Sequence Variants Implicate the TAM (Tyro3, Axl, Mer) Pathway in the Isolated Hypogonadotropic Hypogonadism JCEM 2014 Apr;99(4):1452-60
• Xu M, Shorts-Cary L, DeMasters BK, Lillehei K, Wierman ME. Epidermal growth factor substrate (Eps8) is upregulated in human pituitary tumors: role in proliferation and survival. Endocrinology Epub Dec 2008.
• Ho PM, Barón AE, Wierman ME Deaths and cardiovascular events in men receiving testosterone--reply. JAMA. 2014 Mar 5;311(9):964-5.
• Giustina A, Barkan A, Chanson P, Grossman A, Hoffman A, Ghigo E, Casanueva F, Colao A, Lamberts S, Sheppard M, Melmed S; Pituitary Society; European Neuroendocrine Association: Guidelines for the treatment of growth hormone excess and growth hormone deficiency in adults. J Endocrinol Invest 2008 31: 820-38.
• Salian-Mehta,S Xu M, Pierce A, Bliesner B, Tobet S, Wierman ME. Reproductive Phenotype of Gas6 null mice implicate ligand independent actions of TAM (Tyro3, Axl and Mer) receptors in GnRH neuron development. Mol Cell Endocrinol 2014 Aug 5;393(1-2):164-70.
• Carlson NE, Brenner LA, Wierman ME, Harrison-Felix C, Morey C, Gallagher S, Ripley D: Hypogonadism on admission to acute rehabilitation is correlated with lower functional status at admission and discharge. In press, Brain Injury 2009.
• Kiseljak-Vassiliades K, Carlson NE, Borges MT, Kleinschmidt-DeMasters BK, Lillehei KO, Kerr JM and Wierman ME. Growth Hormone Tumor Histological Subtypes Predict Response to Surgical and Medical Therapy. Endocrine. 2014 E pub, Aug 17.
• Rothman MS Wierman ME: Low Testosterone Levels and the Risk of Metabolic Syndrome in Men. Aging Health, in press, 2009
• Wierman ME, Arlt W, Basson R, Davis SR, Miller KK, Murad MH, Rosner W, and Santoro N. Androgens in Women a reappraisal: the Endocrine Society Clinical Guideline, J Clin Endocrinol Metab 2014 Oct;99(10):3489-510
• Rothman M and Wierman ME. Amenorrhea. In Endocrine Secrets editor M McDermott. in press, 2009.
• Cefalu WT, Nair KS, Seaquist ER, Zierath J, Boulton AJ, LeRoith D, Harrell RM, Grunberger G, Wartofsky L, Gore AC, Wierman ME, Hammes SR, Lange CA, Santen RJ. Statement of principle. Endocr Rev. 2014 Dec;35(6):850.
• Sato J, Kinugasa M, Satomi-Kobayashi S, Hatakeyama K, Knox AJ, Asada Y, Wierman ME, Hirata K, Rikitake Y.Family with sequence similarity 5, member C (FAM5C) increases leukocyte adhesion molecules in vascular endothelial cells: implication in vascular inflammation. PLoS One. 2014 Sep 24;9(9):e107236.
• Wierman ME, Auchus RJ, Haisenleder DJ, Hall JE, Handelsman D, Hankinson S, Rosner W, Singh RJ, Sluss PM, Stanczyk FZ The new instructions to authors for the reporting of steroid hormone measurements. Endocr Rev. 2014 Dec;35(6):849. (also published simultaneously in JCEM, Endocrinology and Hormones in Cancer).
• Pierce AM, Bliesner BS, Xu M, Tobet S, Lemke G, Wierman ME: Axl and Tyro3 Regulate GnRH Neuron Migration and Modulate Female Reproductive Function. The Endocrine Society, San Francisco, CA 2008.
• Ripley D, Wierman M, Gerber D, Weintraub A, Newman J. Comment on the decision to provide testosterone supplementation to patients with traumatic brain injury. PMR. 2014 Aug;6(8):761.
• Shea K, Melanson E, Gavin K, Gibbons E, Stavros A, Wolfe P, Kittelson J, Vondracek S, Gozansky W, Schwartz R, Wierman M, and Kohrt W Body composition and bone mineral density after ovarian hormone suppression with and without estradiol add-back in premenopausal women, 2015, Menopause, Mar 16 E pub.
• Xiong W, Knox AJ, Xu M, Kiseljak-Vassiliades K, Colgan SP, Brodsky K, Kleinschmidt-Demasters B, Lillehei K and Wierman ME. Mammalian Ste20-like Kinase 4 Promotes Pituitary Cell Proliferation and Survival under Hypoxia. Molecular Endocrinology, 2015 29:460-72.
• Knox AJ, McNamara SA, Xu M, Wierman ME : Analysis of Reprimo Expression and function in Pituitary tumors, WSCI Carmel meetings, Carmel CA, 2009.
• Wierman ME. Risks of Different Testosterone Preparations: Too Much, Too Little, Just Right. Invited Commentary. JAMA Internal Medicine 2015, on line May 15.
• Salian-Mehta S, Xu M, McKinsey TM, Tobet S and Wierman ME. Novel Interaction of Class IIb Histone Deacetylase (HDAC) 6 with Class IIa HDAC9 Controls GnRH Neuronal Cell Survival and Migration. , 2015. JBC, in revision.
• Melanson EL, Gavin KM, Shea KL, Wolfe P, Wierman ME, Schwartz RS and Kohrt WM. Ovarian hormone suppression in premenopausal women reduces resting and total energy expenditure. 2015. PLoS One, in review.
• Tobet SA, Wierman ME, Veeramachaneni DNR, Schwarting GE: GnRH neuron migration: a long and dangerous road? The Japanese Endocrine Society , Kyoto Japan, 2009.
• Knox A, Xu M, Plummer L, Slavov D, Taylor D, Pitteloud N, Crowley WF, Wierman ME. Analysis of mutations in Axl and Tyro3 in Probands with Kallmann’s Syndrome and Idiopathic Hypogonadotropic Hypogonadism. The Endocrine Society, Washington DC, 2009
• Rothman MS, Carlson NE, Xu M, Wang C, Swerdloff R, Lee P, Goh V, Ridgway EC, Wierman ME:Reexamination of Testosterone, Dihydrotestosterone and Estradiol Levels Measured by Liquid Chromatography Tandem Mass Spectrometry across the Menstrual Cycle, in Postmenopausal Women and Men across the Lifespan. The Endocrine Society, Washington DC, 2009.
• Rothman MS, Wierman ME: Low testosterone levels and the risk of metabolic syndrome in men Aging Health. 2009
• Xiong W, Matheson CJ, Xu M, Backos DS, Mills TS, Salian-Mehta S, Kiseljak-Vassiliades K, Reigan P, Wierman ME. Structure-based Screen Identification of a Mammalian Ste20-like Kinase 4 (MST4) Inhibitor with Therapeutic Potential for Pituitary Tumors. Mol Cancer Ther. 2015 Dec 31. [Epub ahead of print] PubMed PMID: 26721946
• Melmed S, Colao A, Barkan A, Molitch M, Grossman AB, Kleinberg D, Clemmons D, Chanson P, Laws E, Schlechte J, Vance ML, Ho K, Guistina A: Acromegaly consensus group. Guidelines for acromegaly management: an update. J Clin Endocrinol Metab. 2009 94: 1509-17.
• Kiseljak-Vassiliades K, Xu M, Mills TS, Smith EE, Silveira LJ, Lillehei KO, Kerr JM, Kleinschmidt-DeMasters BK, Wierman ME. Differential somatostatin receptor (SSTR) 1-5 expression and downstream effectors in histologic subtypes of growth hormone pituitary tumors. Mol Cell Endocrinol. 2015 Dec 5;417:73-83. PubMed PMID: 26391562
• Melanson EL, Gavin KM, Shea KL, Wolfe P, Wierman ME, Schwartz RS, Kohrt WM. Regulation of energy expenditure by estradiol in premenopausal women. J Appl Physiol (1985). 2015 Nov 1;119(9):975-81. PubMed PMID: 26338457
• Carlson NE, Brenner LA, Wierman ME, Harrison-Felix C, Morey C, Gallagher S, Ripley D: Hypogonadism on admission to acute rehabilitation is correlated with lower functional status at admission and discharge. Brain Injury 2009 23:336-44.
• Wierman ME, Chin WW, Clemmons DR, Gagel RF, Larsen JL. Changing of the Guard. Endocr Rev. 2015 Aug;36(4):345-6. PubMed PMID: 26240982
• Wierman ME. Risks of Different Testosterone Preparations: Too Much, Too Little, Just Right. JAMA Intern Med. 2015 Jul;175(7):1197-8. PubMed PMID: 25961437
• Salian-Mehta S, Xu M, McKinsey TA, Tobet S, Wierman ME. Novel Interaction of Class IIb Histone Deacetylase 6 (HDAC6) with Class IIa HDAC9 Controls Gonadotropin Releasing Hormone (GnRH) Neuronal Cell Survival and Movement. J Biol Chem. 2015 May 29;290(22):14045-56. PubMed PMID: 25873389
• Shea KL, Gavin KM, Melanson EL, Gibbons E, Stavros A, Wolfe P, Kittelson JM, Vondracek SF, Schwartz RS, Wierman ME, Kohrt WM. Body composition and bone mineral density after ovarian hormone suppression with or without estradiol treatment. Menopause. 2015 Oct;22(10):1045-52. PubMed PMID: 25783468
• Wierman MB, Matecic M, Valsakumar V, Li M, Smith DL Jr, Bekiranov S, Smith JS. Functional genomic analysis reveals overlapping and distinct features of chronologically long-lived yeast populations. Aging (Albany NY). 2015 Mar;7(3):177-94. PubMed PMID: 25769345
• Xu M, Shorts-Cary L, DeMasters BK, Lillehei K, Wierman ME: Epidermal growth factor substrate (Eps8) is upregulated in human pituitary tumors: role in proliferation and survival. Endocrinology 2009 150:2064-71..
• Xiong W, Knox AJ, Xu M, Kiseljak-Vassiliades K, Colgan SP, Brodsky KS, Kleinschmidt-Demasters BK, Lillehei KO, Wierman ME. Mammalian Ste20-like kinase 4 promotes pituitary cell proliferation and survival under hypoxia. Mol Endocrinol. 2015 Mar;29(3):460-72. PubMed PMID: 25650755
• Basson R, Wierman ME, van Lankveld J, Brotto L. Summary of the recommendations on the sexual dysfunctions in women. J Sex Med 2010 7:314-26.
• Wierman ME, Nappi RE, Avis N, Davis SR, Sabrie F, Rosner W, Shifren JL. Endocrine aspects of women’s sexual function. J Sex Med 2010 7: 561-85
• Cefalu WT, Nair KS, Seaquist ER, Zierath J, Boulton AJ, LeRoith D, Harrell RM, Grunberger G, Wartofsky L, Gore AC, Wierman ME, Hammes SR, Lange CA, Santen RJ. Statement of principle. Horm Cancer. 2015 Feb;6(1):1. PubMed PMID: 25410830
• Kiseljak-Vassiliades K, Carlson NE, Borges MT, Kleinschmidt-DeMasters BK, Lillehei KO, Kerr JM, Wierman ME. Growth hormone tumor histological subtypes predict response to surgical and medical therapy. Endocrine. 2015 May;49(1):231-41. PubMed PMID: 25129651
• Lillehei KO, Widdel L, Arias Astete CA, Wierman ME, DKleinschmidt-DeMasters B, Kerr J. Transphenoidal Resection of 100 Rathke’s Cleft Cysts: limited value of alcohol cauterization in reducing recurrence rates. J Neurosurgery in revision, 2010.
• Basson R, Wierman ME, van Lankveld J, Brotto L. Summary of the recommendations on the sexual dysfunctions in women. J Sex Med 2010 7:314-26.
• Wierman ME, Nappi RE, Avis N, Davis SR, Sabrie F, Rosner W, Shifren JL. Endocrine aspects of women’s sexual function. J Sex Med 2010 7: 561-85.
• Wierman ME, Kiseljak-Vassilliades K, Tobet S. Gonadotropin Releasing Hormone (GnRH) Neuronal Migration : Initiation, Maintenance and Cessation as Critical Steps to Ensure Normal Reproductive Function. Frontiers in Neuroscience 2011 32:43-52.
• Rothman M, Carlson N, Xu M, Goh V, Lee W, Swerdloff R, Ridgway EC, Wang C, Wierman ME. Reexamination of Testosterone, Dihydrotestosterone, Estradiol and Estrone Levels Across the Menstrual Cycle and in Post Menopausal Women Measured by Liquid Chromatography Tandem Mass Spectrometry Steroids 2011 76:177-82.
• Rothman MS and Wierman ME. How should postmenopausal androgen excess be evaluated? Clinical Endocrinology 2011, in press.
• Xiong W, Matheson CJ, Xu M, Backos DS, Mills TS, Salian-Mehta S, Kiseljak-Vassiliades K, Reigan P, Wierman ME. Structure-Based Screen Identification of a Mammalian Ste20-like Kinase 4 (MST4) Inhibitor with Therapeutic Potential for Pituitary Tumors. Mol Cancer Ther. 2016 Mar;15(3):412-20. PubMed PMID: 26721946
• Pierce A, Xu M, Bliesner B, Richards J, Liu Z, Tobet S, Wierman ME. Steroid Hormone Feedback in the Hypothalamic-Pituitary-Gonadal Axis requires Axl /Tyro3 Signaling Molecular and Cellular Endocrinology 2011, in press
• Knox AJ, Xu M, Plummer L, Au M, Slavov D, Taylor M, Bevers S, Hodges RS, Pitteloud N, Crowley WF Jr,. Wierman ME. ,AXL Mutations Implicate the TAM (Tyro3, Axl, Mer) Pathway in the Isolated GnRH Deficiency of Kallmann Syndrome (KS) and Normosmic Idiopathic Hypogonadotropic Hypogonadism (nIHH) JCEM 2011, in revision.
• Wierman ME, Chin WW, Clemmons DR, Gagel RF, Larsen JL. Changing of the Guard. Endocr Rev. 2016 Feb;2016(1):1-2. PubMed PMID: 27454359
• Michaelis KA, Knox AJ, Xu M, Kiseljak-Vassiliades K, Edwards ME, Geraci M , Kleinschmidt-DeMasters B, Lillehei KO, Wierman ME. Identification of Growth Arrest and DNA-Damage-Inducible Gene ß (GADD45ß) as a Novel Tumor Suppressor in Pituitary Gonadotrope Tumors Endocrinology 2011, in revision.
• Kiseljak-Vassiliades K, Mills TS, Zhang Y, Xu M, Lillehei KO, Kleinschmidt-DeMasters BK, Wierman ME. Elucidating the Role of the Desmosome Protein p53 Apoptosis Effector Related to PMP-22 (PERP) in Growth Hormone Tumors. Endocrinology. 2017 Feb 9. [Epub ahead of print] PubMed PMID: 28323918
• Wierman ME, Xu M, Pierce A, Bliesner B, Bliss SP, Roberson MS. Extracellular Signal-regulated Kinase (ERK) 1 and ERK2 are not Required for GnRH Neuron Development and Normal Female Reproductive Axis Function in Mice. Neuroendocrinology, in review.
• Knox AJ, Xu M, Michaelis KA, Kleinsmidt-DeMasters B, Lillehei KO, Wierman ME. Reprimo (RPRM) is Downregulated in Human Gonadotrope Pituitary Tumors and protein levels upregulated with cellular stress. Molecular Endocrinology 2011, in review.
• Huang J, Rothman M and Wierman ME: Premature Gonadal Insufficiency. Immunoendocrinology: Scientific and Clinical Aspects Contemporary Endocrinology, 2011 519-34.
• . Lillehei KO, Widdel L, Arias Astete CA, Wierman ME, Kleinschmidt-DeMasters B, Kerr JM. Transpenoidal resection of 100 rathke?s cleft cysts: limited value of alcohol cauterization in reducing recurrence rates. JNeurosurgery 2011 114:310-7.
• Kiseljak-Vassiliades K, Zhang Y, Bagby S, Kar A, Pozdeyev N, Xu M, Gowan K, Sharma V, Raeburn CD, Albuja-Cruz M, Jones KL, Fishbein L, Schweppe R, Somerset HL, Pitts TM, Leong S, Wierman M. Development of new preclinical models to advance adrenocortical carcinoma research. Endocr Relat Cancer. 2018 Jan 25. [Epub ahead of print] PubMed PMID: 29371329
• Carr SB, Kleinschmidt-DeMasters BK, Kerr JM, Kiseljak-Vassiliades K, Wierman ME, Lillehei KO. Negative surgical exploration in patients with Cushing's disease: benefit of two-thirds gland resection on remission rate and a review of the literature. J Neurosurg. 2017 Dec 8;:1-8. [Epub ahead of print] PubMed PMID: 29219752
• Meditz A, Moreau K, Gozansky W, Kelsey M, Kohrt W, Wierman ME Connick L. Healthy Postmeonpausal Women have higher percentages of CCR5+ Cervial CD4+T cells compared to Premenopausal Women: implications for HIV transmission. Conference on Retroviruses and Opportunistic Infections (CRO1 2011), Boston, MA.
• Kohrt WM, Wierman ME. Preventing Fat Gain by Blocking Follicle-Stimulating Hormone. N Engl J Med. 2017 Jul 20;377(3):293-295. PubMed PMID: 28723332
• Knox AJ,Edwards MG, Kiseljak-Vassiliades K, Xu M, Michaelis KA, Kleinschmidt-Demasters B, Lillehei KO and Wierman ME. Gene amplification and upregulation of mammalian STE20-like protein kinase 4 (MST4) reveal a novel candidate gene in human pituitary tumorigenesis. The Endocrine Society, Boston, MA, June 2011.
• Kiseljak-Vassiliades K, Mills TS, Zhang Y, Xu M, Lillehei KO, Kleinschmidt-DeMasters BK, Wierman ME. Elucidating the Role of the Desmosome Protein p53 Apoptosis Effector Related to PMP-22 in Growth Hormone Tumors. Endocrinology. 2017 May 1;158(5):1450-1460. PubMed PMID: 28323918
• Kiseljak-Vassiliades K, Xu M, Knox AJ, Edwards MG, Michaelis KA, Kleinschmidt-Demasters B, Lillehei KO, Geraci M and Wierman ME. Pro-Survival and Tumorigenicity of LAG1 Homolog Ceramide Synthase 6 (LASS6) in Gonadotrope Pituitary Tumors. The Endocrine Society, Boston, MA, June 2011
• Salian Mehta S, Xu M, Schaller M and Wierman ME. Axl and Met: Crosstalk of Tyrosine Kinase Receptor Signaling in GnRH Neurons. The Endocrine Society, Boston, MA, June 2011.
• Michaelis K, Knox AJ, Xu M, Kiseljak-Vassiliades K, Edwards MG, Kleinschmidt-DeMasters BK, Lillehei K, Geraci M, and Wierman ME. Repression of GADD45ß in Human Gonadotrope Pituitary Tumors: Role in Proliferation, Survival and Tumorigenesis. The Endocrine Society, Boston, MA June 2011.
• Thompson IB, Tang D, Xu S, Wierman ME, Laws ER, Shi Y, Carroll RS and Kaiser UB. Upregulation of Histone Modifying Enzymes: Implications in the Pathogenesis of Human Pituitary Adenomas. The Endocrine Society, Boston, MA, June 2011.
• Shuen AY, Lanni S, Panigrahi GB, Edwards M, Yu L, Campbell BB, Mandel A, Zhang C, Zhukova N, Alharbi M, Bernstein M, Bowers DC, Carroll S, Cole KA, Constantini S, Crooks B, Dvir R, Farah R, Hijiya N, George B, Laetsch TW, Larouche V, Lindhorst S, Luiten RC, Magimairajan V, Mason G, Mason W, Mordechai O, Mushtaq N, Nicholas G, Oren M, Palma L, Pedroza LA, Ramdas J, Samuel D, Wolfe Schneider K, Seeley A, Semotiuk K, Shamvil A, Sumerauer D, Toledano H, Tomboc P, Wierman M, Van Damme A, Lee YY, Zapotocky M, Bouffet E, Durno C, Aronson M, Gallinger S, Foulkes WD, Malkin D, Tabori U, Pearson CE. Functional Repair Assay for the Diagnosis of Constitutional Mismatch Repair Deficiency From Non-Neoplastic Tissue. J Clin Oncol. 2019 Jan 4;:JCO1800474. [Epub ahead of print] PubMed PMID: 30608896
• Lillehei KO, Widdel L, Arias Astete CA, Wierman ME, Kleinschmidt-DeMasters B, Kerr JM. Transpenoidal resection of 100 rathke’s cleft cysts: limited value of alcohol cauterization in reducing recurrence rates. JNeurosurgery 2011 114:310-7.
• Wierman ME, Kiseljak-Vassilliades K, Tobet S. Gonadotropin Releasing Hormone (GnRH) Neuronal Migration : Initiation, Maintenance and Cessation as Critical Steps to Ensure Normal Reproductive Function. Frontiers in Neuroscience 2011 32:43-52.
• Rothman M, Carlson N, Xu M, Goh V, Lee W, Swerdloff R, Ridgway EC, Wang C, Wierman ME. Reexamination of Testosterone, Dihydrotestosterone, Estradiol and Estrone Levels Across the Menstrual Cycle and in Post Menopausal Women Measured by Liquid Chromatography Tandem Mass Spectrometry Steroids 2011 76:177-82.
• Grossmann M, Wierman ME, Angus P, Handelsman DJ. Reproductive Endocrinology of Non-Alcoholic Fatty Liver Disease. Endocr Rev. 2018 Nov 30. [Epub ahead of print] PubMed PMID: 30500887
• Deaver KE, Catel CP, Lillehei KO, Wierman ME, Kerr JM. Strategies to reduce readmissions for hyponatremia after transsphenoidal surgery for pituitary adenomas. Endocrine. 2018 Nov;62(2):333-339. PubMed PMID: 29961198
• Kiseljak-Vassiliades K, Zhang Y, Kar A, Razzaghi R, Xu M, Gowan K, Raeburn CD, Albuja-Cruz M, Jones KL, Somerset H, Fishbein L, Leong S, Wierman ME. Elucidating the Role of the Maternal Embryonic Leucine Zipper Kinase in Adrenocortical Carcinoma. Endocrinology. 2018 Jul 1;159(7):2532-2544. PubMed PMID: 29790920
• Kiseljak-Vassiliades K, Zhang Y, Bagby SM, Kar A, Pozdeyev N, Xu M, Gowan K, Sharma V, Raeburn CD, Albuja-Cruz M, Jones KL, Fishbein L, Schweppe RE, Somerset H, Pitts TM, Leong S, Wierman ME. Development of new preclinical models to advance adrenocortical carcinoma research. Endocr Relat Cancer. 2018 Apr;25(4):437-451. PubMed PMID: 29371329
• Rothman MS and Wierman ME. How should postmenopausal androgen excess be evaluated? Clinical Endocrinology 2011 75:160-164.
• Pierce A, Xu M, Bliesner B, Richards J, Liu Z, Tobet S, Wierman ME. Hypothalamic but not Pituitary or ovarian defects underlie the reproductive abnormalities in Axl /Tyro3 null mice. Molecular and Cellular Endocrinology 2011339:151-158.
• Melanson EL, Lyden K, Gibbons E, Gavin KM, Wolfe P, Wierman ME, Schwartz RS, Kohrt WM. Influence of Estradiol Status on Physical Activity in Premenopausal Women. Med Sci Sports Exerc. 2018 Aug;50(8):1704-1709. PubMed PMID: 29509642
• Kerr JM, Wierman ME. Pituituary apoplexy. BMJ 2011 342:1270
• Gavin KM, Shea KL, Gibbons E, Wolfe P, Schwartz RS, Wierman ME, Kohrt WM. Gonadotropin-releasing hormone agonist in premenopausal women does not alter hypothalamic-pituitary-adrenal axis response to corticotropin-releasing hormone. Am J Physiol Endocrinol Metab. 2018 Aug 1;315(2):E316-E325. PubMed PMID: 29631362
• Roof AK, Jirawatnotai S, Trudeau T, Kuzyk C, Wierman ME, Kiyokawa H, Gutierrez-Hartmann A. The Balance of PI3K and ERK Signaling Is Dysregulated in Prolactinoma and Modulated by Dopamine. Endocrinology. 2018 Jun 1;159(6):2421-2434. PubMed PMID: 29726995
• Madsen H, Borges TM, Knox AJ, Michaelis KA, Xu M, Lillehei KO, Wierman ME and Kleinschmidt DeMasters B. Giant Pituitary Adenomas: pathologic-radiographic correlations and lack of role for p53 and MIB-1 labeling. American Journal of Surgical Pathology, 2011 35:1204-1213.
• Michaelis KA, Knox AJ, Xu M, Kiseljak-Vassiliades K, Edwards ME, Geraci M , Kleinschmidt-DeMasters B, Lillehei KO, Wierman ME. Identification of Growth Arrest and DNA-Damage-Inducible Gene ß (GADD45ß) as a Novel Tumor Suppressor in Pituitary Gonadotrope Tumors Endocrinology 2011 152:3603-13.
• Wierman ME, Xu M, Pierce A, Bliesner B, Bliss SP, Roberson MS. Extracellular Signal-regulated Kinase (ERK) 1 and ERK2 are not Required for GnRH Neuron Development and Normal Female Reproductive Axis Function in Mice. Neuroendocrinology, in press.
• Carr SB, Kleinschmidt-DeMasters BK, Kerr JM, Kiseljak-Vassiliades K, Wierman ME, Lillehei KO. Negative surgical exploration in patients with Cushing's disease: benefit of two-thirds gland resection on remission rate and a review of the literature. J Neurosurg. 2018 Nov 1;129(5):1260-1267. PubMed PMID: 29219752
• Knox AJ, Xu M, Michaelis KA, Kleinsmidt-DeMasters B, Lillehei KO, Wierman ME. Reprimo (RPRM) is Downregulated in Human Gonadotrope Pituitary Tumors and protein levels upregulated with cellular stress. Endocrinology 2012, in press.
• Meditz AL, Moreau KL, MaWhinney S, Gozansky WS, Melander K, Kohrt, WM, Wierman, ME, and Connick E. CCR5 Expression is Elevated on Endocervical CD4+ T-Cells in Healthy Postmenopausal Women, JAIDS 2011, in press.
• . Weickhardt AJ, Rothman M,Salian-Mehta S, Kiseljak-Vassiliades K, Oton AB, Doebele RC, Wierman ME, Cambidge DR. Rapid and Reversible Hypogonadism secondary to Crizotinib Use in Men with Metastatic Non-small cell Lung Cancer. Cancer, 2012, in press.
• Kiseljak-Vassiliades K, Shafi S, Kerr JM, Kleinschmidt-DeMasters B and Wierman ME Clinical Implications of Growth Hormone Tumor Subtypes: Ppast and Present, Endocrine 2012, in press.
• Head L, Kiseljak-Vassiliades K, Clark TJ, Somerset H, King J, Raeburn C, Albuja-Cruz M, Weyant M, Cleveland J, Wierman ME, Leong S. Response to Immunotherapy in Combination With Mitotane in Patients With Metastatic Adrenocortical Cancer. J Endocr Soc. 2019 Dec 1;3(12):2295-2304. PubMed PMID: 31745526
• Lang J, Capasso A, Jordan KR, French JD, Kar A, Bagby SM, Barbee J, Yacob BW, Head LS, Tompkins KD, Freed BM, Somerset H, Clark TJ, Pitts TM, Messersmith WA, Eckhardt SG, Wierman ME, Leong S, Kiseljak-Vassiliades K. Development of an Adrenocortical Cancer Humanized Mouse Model to Characterize Anti-PD1 Effects on Tumor Microenvironment. J Clin Endocrinol Metab. 2020 Jan 1;105(1). PubMed PMID: 31513709
• Mehta S, Xu M, McKinsey T, Wierman ME. Deciphering the role of histone deacetylases in GnRH neuronal development. Society for Neuroscience, Washington, DC, Nov 2011.
• Davis SR, Baber R, Panay N, Bitzer J, Perez SC, Islam RM, Kaunitz AM, Kingsberg SA, Lambrinoudaki I, Liu J, Parish SJ, Pinkerton J, Rymer J, Simon JA, Vignozzi L, Wierman ME. Global Consensus Position Statement on the Use of Testosterone Therapy for Women. J Clin Endocrinol Metab. 2019 Oct 1;104(10):4660-4666. PubMed PMID: 31498871
• Wierman, ME Fertility Options in Women and Men with Hypopituitarism, International Congress of Endocrinology, Florence Italy 5/2012
• Davis SR, Baber R, Panay N, Bitzer J, Perez SC, Islam RM, Kaunitz AM, Kingsberg SA, Lambrinoudaki I, Liu J, Parish SJ, Pinkerton J, Rymer J, Simon JA, Vignozzi L, Wierman ME. Global Consensus Position Statement on the Use of Testosterone Therapy for Women. J Sex Med. 2019 Sep;16(9):1331-1337. PubMed PMID: 31488288
• Kiseljak-Vassiliades K, Shibana S, Demasters BK, Lillehei K Kerr JM, Wierman ME: Clinical and Genomic Profiling of Growth Hormone Tumor Subtypes to Identify Mechanisms of Disease Pathogenesis, Aggressivness, and Response to Therapy, The Endocrine Society, Houston Tx June 2012.
• Davis SR, Baber R, Panay N, Bitzer J, Perez SC, Islam RM, Kaunitz AM, Kingsberg SA, Lambrinoudaki I, Liu J, Parish SJ, Pinkerton J, Rymer J, Simon JA, Vignozzi L, Wierman ME. Global Consensus Position Statement on the use of Testosterone Therapy for Women. Maturitas. 2019 Oct;128:89-93. PubMed PMID: 31484631
• Salian-Mehta1 S, Xu M, Busta E, Horn T, Mckinsey T and Wierman ME Epigenetic control of GnRH neuron development: role of histone deacetylase 9 (HDAC9) The Endocrine Society, Houston, Tx June 2012.
• Davis SR, Baber R, Panay N, Bitzer J, Cerdas Perez S, Islam RM, Kaunitz AM, Kingsberg SA, Lambrinoudaki I, Liu J, Parish SJ, Pinkerton J, Rymer J, Simon JA, Vignozzi L, Wierman ME. Global Consensus Position Statement on the Use of Testosterone Therapy for Women. Climacteric. 2019 Oct;22(5):429-434. PubMed PMID: 31474158
• Wierman ME, Xu M, Pierce A, Bliesner B, Bliss SP, Roberson MS. Extracellular Signal-regulated Kinase (ERK) 1 and ERK2 are not Required for GnRH Neuron Development and Normal Female Reproductive Axis Function in Mice. Neuroendocrinology, 2012 95:289-96.
• Kar A, Zhang Y, Yacob B, Saeed JM, Tompkins KD, Bagby S, Pitts TM, Somerset HL, Leong S, Wierman M, Kiseljak-Vassiliades K. Targeting PDZ binding kinase is anti-tumorigenic in novel preclinical models of ACC. Endocr Relat Cancer. 2019 Jul 1. [Epub ahead of print] PubMed PMID: 31325906
• Hadjidemetriou I, Mariniello K, Ruiz-Babot G, Pittaway J, Mancini A, Mariannis D, Gomez-Sanchez CE, Parvanta L, Drake WM, Chung TT, Abdel-Aziz TE, DiMarco A, Palazzo FF, Wierman ME, Kiseljak-Vassiliades K, King PJ, Guasti L. DLK1/PREF1 marks a novel cell population in the human adrenal cortex. J Steroid Biochem Mol Biol. 2019 Oct;193:105422. PubMed PMID: 31265901
• Swanson CM, Blatchford PJ, Orwoll ES, Cauley JA, LeBlanc ES, Fink HA, Wright KP Jr, Wierman ME, Kohrt WM, Stone KL. Association between objective sleep duration and bone mineral density in older postmenopausal women from the Study of Osteoporotic Fractures (SOF). Osteoporos Int. 2019 Oct;30(10):2087-2098. PubMed PMID: 31139855
• Iwamoto SJ, T'Sjoen G, Safer JD, Davidge-Pitts CJ, Wierman ME, Glodowski MB, Rothman MS. Letter to the Editor: "Progesterone Is Important for Transgender Women's Therapy-Applying Evidence for the Benefits of Progesterone in Ciswomen". J Clin Endocrinol Metab. 2019 Aug 1;104(8):3127-3128. PubMed PMID: 30860591
• Shuen AY, Lanni S, Panigrahi GB, Edwards M, Yu L, Campbell BB, Mandel A, Zhang C, Zhukova N, Alharbi M, Bernstein M, Bowers DC, Carroll S, Cole KA, Constantini S, Crooks B, Dvir R, Farah R, Hijiya N, George B, Laetsch TW, Larouche V, Lindhorst S, Luiten RC, Magimairajan V, Mason G, Mason W, Mordechai O, Mushtaq N, Nicholas G, Oren M, Palma L, Pedroza LA, Ramdas J, Samuel D, Wolfe Schneider K, Seeley A, Semotiuk K, Shamvil A, Sumerauer D, Toledano H, Tomboc P, Wierman M, Van Damme A, Lee YY, Zapotocky M, Bouffet E, Durno C, Aronson M, Gallinger S, Foulkes WD, Malkin D, Tabori U, Pearson CE. Functional Repair Assay for the Diagnosis of Constitutional Mismatch Repair Deficiency From Non-Neoplastic Tissue. J Clin Oncol. 2019 Feb 20;37(6):461-470. PubMed PMID: 30608896
• Grossmann M, Wierman ME, Angus P, Handelsman DJ. Reproductive Endocrinology of Nonalcoholic Fatty Liver Disease. Endocr Rev. 2019 Apr 1;40(2):417-446. PubMed PMID: 30500887
• Knox AJ, Xu M, Michaelis KA, Kleinsmidt-DeMasters B, Lillehei KO, Wierman ME. Reprimo (RPRM) is Downregulated in Human Gonadotrope Pituitary Tumors and protein levels upregulated with cellular stress. Endocrinology 2012 153:2963-73.
• Meditz AL, Moreau KL, MaWhinney S, Gozansky WS, Melander K, Kohrt, WM, Wierman, ME, and Connick E. CCR5 Expression is Elevated on Endocervical CD4+ T-Cells in Healthy Postmenopausal Women, JAIDS 2012 59:221-228.
• Weickhardt AJ, Rothman M,Salian-Mehta S, Kiseljak-Vassiliades K, Oton AB, Doebele RC, Wierman ME, Cambidge DR. Rapid Onset Hypogonadism secondary to Crizotinib Use in Men with Metastatic Non-small cell Lung Cancer. Cancer 2012 118: 5302-9.
• Kiseljak-Vassiliades K, Shibana S, Xu M, Demasters BK, Lillehei K, Kerr J, Wierman ME. Growth hormone subtypes, Endocrine 2012 42:18-28.
• Weickhardt AJ, Rothman M, Kiseljak-Vassiliades K, Oton AB, Doebele RC, Wierman ME, Cambidge DR. Symptomatic reduction in free testosterone levels secondary to crizotinib use in male cancer patients, Cancer 2013, in press.
• Wierman ME. Why Focus on Androgens in Women?. Endocrinol Metab Clin North Am. 2021 Mar;50(1):xv-xvi. PubMed PMID: 33518191
• Mehta SM, Xu M and Wierman ME. AXL and MET Crosstalk to Promote Gonadotropin Releasing Hormone (GnRH) Neuronal Cell Migration and Survival, Molecular Cellular Endocrinology, 2013, in press.
• Wierman ME. Hyperandrogenic Anovulation: Differential Diagnosis and Evaluation. Endocrinol Metab Clin North Am. 2021 Mar;50(1):1-10. PubMed PMID: 33518178
• Rosner W, Hankinson SE, Sluss P, Vesper HW, Wierman ME. Challenges to the Measurement of Estradiol An Endocrine Society Position Statement, J Clin Endocrinol Metab 2013, in press.
• Swanson CM, Blatchford PJ, Stone KL, Cauley JA, Lane NE, Rogers-Soeder TS, Redline S, Bauer DC, Wright KP Jr, Wierman ME, Kohrt WM, Orwoll ES. Sleep duration and bone health measures in older men. Osteoporos Int. 2020 Sep 15. [Epub ahead of print] PubMed PMID: 32930851
• Giustina A, Barkhoudarian G, Beckers A, Ben-Shlomo A, Biermasz N, Biller B, Boguszewski C, Bolanowski M, Bollerslev J, Bonert V, Bronstein MD, Buchfelder M, Casanueva F, Chanson P, Clemmons D, Fleseriu M, Formenti AM, Freda P, Gadelha M, Geer E, Gurnell M, Heaney AP, Ho KKY, Ioachimescu AG, Lamberts S, Laws E, Losa M, Maffei P, Mamelak A, Mercado M, Molitch M, Mortini P, Pereira AM, Petersenn S, Post K, Puig-Domingo M, Salvatori R, Samson SL, Shimon I, Strasburger C, Swearingen B, Trainer P, Vance ML, Wass J, Wierman ME, Yuen KCJ, Zatelli MC, Melmed S. Multidisciplinary management of acromegaly: A consensus. Rev Endocr Metab Disord. 2020 Dec;21(4):667-678. PubMed PMID: 32914330
• Davis EE, Balasubramanian R, Kupchinsky ZA, Keefe DL, Plummer L, Khan K, Meczekalski B, Heath KE, Lopez-Gonzalez V, Ballesta-Martinez MJ, Margabanthu G, Price S, Greening J, Brauner R, Valenzuela I, Cusco I, Fernandez-Alvarez P, Wierman ME, Li T, Lage K, Barroso PS, Chan YM, Crowley WF, Katsanis N. TCF12 haploinsufficiency causes autosomal dominant Kallmann syndrome and reveals network-level interactions between causal loci. Hum Mol Genet. 2020 Aug 11;29(14):2435-2450. PubMed PMID: 32620954
• Kar A, Wierman ME, Kiseljak-Vassiliades K. Update on in-vivo preclinical research models in adrenocortical carcinoma. Curr Opin Endocrinol Diabetes Obes. 2020 Jun;27(3):170-176. PubMed PMID: 32304391
• Ripley DL, Gerber D, Pretz C, Weintraub AH, Wierman ME. Testosterone replacement in hypogonadal men during inpatient rehabilitation following traumatic brain injury: Results from a double-blind, placebo-controlled clinical pilot study. NeuroRehabilitation. 2020;46(3):355-368. PubMed PMID: 32250330
• Weigand I, Schreiner J, Röhrig F, Sun N, Landwehr LS, Urlaub H, Kendl S, Kiseljak-Vassiliades K, Wierman ME, Angeli JPF, Walch A, Sbiera S, Fassnacht M, Kroiss M. Active steroid hormone synthesis renders adrenocortical cells highly susceptible to type II ferroptosis induction. Cell Death Dis. 2020 Mar 17;11(3):192. PubMed PMID: 32184394
• Schreiber AR, Kar A, Goodspeed AE, Pozdeyev N, Somerset H, Raeburn CD, Tan AC, Leong S, Wierman ME, Kiseljak-Vassiliades K. Leptomeningeal Metastasis from Adrenocortical Carcinoma: A Case Report. J Endocr Soc. 2020 Mar 1;4(3):bvaa017. PubMed PMID: 32154490
• Lang J, Capasso A, Jordan KR, French JD, Kar A, Bagby SM, Barbee J, Yacob BW, Head LS, Tompkins KD, Freed BM, Somerset H, Clark TJ, Pitts TM, Messersmith WA, Eckhardt SG, Wierman ME, Leong S, Kiseljak-Vassiliades K. Development of an Adrenocortical Cancer Humanized Mouse Model to Characterize Anti-PD1 Effects on Tumor Microenvironment. J Clin Endocrinol Metab. 2020 Jan 1;105(1). PubMed PMID: 31513709
• Santoro N, Wierman ME. Do Women Need Androgens Like a Fish Needs a Bicycle? A Review of the Literature and Clinical Guidelines. Clin Obstet Gynecol. 2021 Dec 1;64(4):784-792. PubMed PMID: 34560765
• Pozdeyev N, Fishbein L, Gay LM, Sokol ES, Hartmaier R, Ross JS, Darabi S, Demeure MJ, Kar A, Foust LJ, Koc K, Bowles DW, Leong S, Wierman ME, Kiseljak-Vassiliades K. Targeted genomic analysis of 364 adrenocortical carcinomas. Endocr Relat Cancer. 2021 Aug 16;28(10):671-681. PubMed PMID: 34410225
• Alzofon N, Koc K, Panwell K, Pozdeyev N, Marshall CB, Albuja-Cruz M, Raeburn CD, Nathanson KL, Cohen DL, Wierman ME, Kiseljak-Vassiliades K, Fishbein L. Mastermind Like Transcriptional Coactivator 3 (MAML3) Drives Neuroendocrine Tumor Progression. Mol Cancer Res. 2021 Sep;19(9):1476-1485. PubMed PMID: 33986121
• Maria AG, Silva Borges K, Lira RCP, Hassib Thomé C, Berthon A, Drougat L, Kiseljak-Vassiliades K, Wierman ME, Faucz FR, Faça VM, Tone LG, Stratakis CA. Inhibition of Aurora kinase A activity enhances the antitumor response of beta-catenin blockade in human adrenocortical cancer cells. Mol Cell Endocrinol. 2021 May 15;528:111243. PubMed PMID: 33716050
• Pino-Jones AD, Cervantes L, Flores S, Jones CD, Keach J, Ngov LK, Schwartz DA, Wierman M, Anstett T, Bowden K, Keniston A, Burden M. Advancing Diversity, Equity, and Inclusion in Hospital Medicine. J Hosp Med. 2021 Apr;16(4):198-203. PubMed PMID: 33617435
• Wierman ME. Why Focus on Androgens in Women?. Endocrinol Metab Clin North Am. 2021 Mar;50(1):xv-xvi. PubMed PMID: 33518191
• Wierman ME. Hyperandrogenic Anovulation: Differential Diagnosis and Evaluation. Endocrinol Metab Clin North Am. 2021 Mar;50(1):1-10. PubMed PMID: 33518178
• Swanson CM, Blatchford PJ, Stone KL, Cauley JA, Lane NE, Rogers-Soeder TS, Redline S, Bauer DC, Wright KP Jr, Wierman ME, Kohrt WM, Orwoll ES. Sleep duration and bone health measures in older men. Osteoporos Int. 2021 Mar;32(3):515-527. PubMed PMID: 32930851
• Warmington E, Smith G, Chortis V, Liang R, Lippert J, Steinhauer S, Landwehr LS, Hantel C, Kiseljak-Vassiliades K, Wierman ME, Altieri B, Foster PA, Ronchi CL. PLK1 inhibitors as a new targeted treatment for adrenocortical carcinoma. Endocr Connect. 2024 Jan 1;13(1). PubMed PMID: 37992487
• Rosenberg R, Raeburn CD, Clay MR, Wierman ME. Dual Aldosterone- and Cortisol-Secreting Adrenal Cortical Carcinoma: Pre- and Perioperative Evaluation and Management. JCEM Case Rep. 2023 Jul;1(4):luad073. PubMed PMID: 37909000
• Wierman ME, Kiseljak-Vassiliades K. Should Dehydroepiandrosterone Be Administered to Women?. J Clin Endocrinol Metab. 2022 May 17;107(6):1679-1685. PubMed PMID: 35254428
• McDonald HG, Sarvestani AL, Owen JW, Rueckert J, Wierman ME, Kiseljak-Vassiliades K, Pandalai PK, Ellis CS, Patel RA, Del Rivero J, Hernandez JM, Cavnar MJ. Response of adrenocortical carcinoma liver metastases to hepatic artery infusion floxuridine. HPB (Oxford). 2023 Nov;25(11):1446-1449. PubMed PMID: 37453816
• Tahmasbi Sohi M, Cali M, Forster JE, Kiseljak-Vassiliades K, Wierman ME. Short term effects of intraarticular triamcinolone acetonide injection on serum testosterone, luteinizing hormone, and follicle stimulating hormone levels in male veterans: A prospective pilot study. PM R. 2023 May 25. [Epub ahead of print] PubMed PMID: 37229562
• Ruggiero C, Tamburello M, Rossini E, Zini S, Durand N, Cantini G, Cioppi F, Hantel C, Kiseljak-Vassiliades K, Wierman ME, Landwehr LS, Weigand I, Kurlbaum M, Zizioli D, Turtoi A, Yang S, Berruti A, Luconi M, Sigala S, Lalli E. FSCN1 as a new druggable target in adrenocortical carcinoma. Int J Cancer. 2023 Jul 1;153(1):210-223. PubMed PMID: 36971100

Professional Memberships

• International Endocrine Society, President
• The Endocrine Society, member
• The Pituitary Society, member
• A5 Adrenal cancer society, member

Practice Locations

UCHealth Anschutz Outpatient Pavilion - Anschutz Medical Campus
1635 Aurora Ct
Aurora, CO 80045
720-848-0000

Denver Veterans Affairs Medical Center
1055 Clermont St
Denver, CO 80220
1-888-336-8262

UCHealth Diabetes and Endocrinology Clinic - Anschutz Medical Campus
1635 Aurora Ct
6th Floor
Aurora, CO 80045
720-848-2650

Hospital Affiliation

• University of Colorado Hospital
• Veterans Affairs Medical Center

Center Affiliations

• Center for Women's Health Research
• Colorado Clinical & Translational Sciences Institute (CCTSI)
• Center for Neuroscience
• University of Colorado Cancer Center

Specialty Information

Specialties

• Internal Medicine, Board Certification (1982)
• Endocrinology, Diabetes and Metabolism, Board Certification (1985)

Conditions & Treatments

• Brain and Nervous System - Pituitary Disorders
• Endocrine System (Hormones) - Endocrine Cancer (Parathyroid, Adrenal, Carcinoid)
• Endocrine System (Hormones) - Thyroid Disease
• Endocrine System (Hormones) - Adrenal Diseases
• Men's Health - Infertility and Reproductive Medicine
• Women's Health - Contraception
• Women's Health - Hormone Replacement Therapy
• Women's Health - Menopause
• Endocrine System (Hormones)
• Brain and Nervous System
• Men's Health
• Women's Health