Seth Furgeson, MD

Publications

• Mechanisms of type I and type II pseudohypoaldosteronism. Furgeson SB, Linas S. J Am Soc Nephrol. 2010 Nov;21(11):1842-5. Epub 2010 Sep 9
• Serum response factor regulates expression of phosphatase and tensin homolog through a microRNA network in vascular smooth muscle cells. Horita HN, Simpson PA, Ostriker A, Furgeson S, Van Putten V, Weiser-Evans MC, Nemenoff RA. Arterioscler Thromb Vasc Biol. 2011 Dec;31(12):2909-19. Epub 2011 Sep 22.
• SDF-1a induction in mature smooth muscle cells by inactivation of PTEN is a critical mediator of exacerbated injury-induced neointima formation. Nemenoff RA, Horita H, Ostriker AC, Furgeson SB, Simpson PA, VanPutten V, Crossno J, Offermanns S, Weiser-Evans MC. Arterioscler Thromb Vasc Biol. 2011 Jun;31(6):1300-8. Epub 2011 Mar 17.
• Moulton KS, Li M, Strand K, Burgett S, McClatchey P, Tucker R, Furgeson SB, Lu S, Kirkpatrick B, Cleveland JC, Nemenoff RA, Ambardekar AV, Weiser-Evans MC. PTEN deficiency promotes pathological vascular remodeling of human coronary arteries. JCI Insight. 2018 Feb 22;3(4). [Epub ahead of print] PubMed PMID: 29467331
• Montford JR, Lehman AMB, Bauer CD, Klawitter J, Klawitter J, Poczobutt JM, Scobey M, Weiser-Evans M, Nemenoff RA, Furgeson SB. Bone marrow-derived cPLA2a contributes to renal fibrosis progression. J Lipid Res. 2018 Feb;59(2):380-390. PubMed PMID: 29229740
• Montford JR, Furgeson SB. A new CTGF target in renal fibrosis. Kidney Int. 2017 Oct;92(4):784-786. PubMed PMID: 28938948
• Moulton KS, Li M, Strand K, Burgett S, McClatchey P, Tucker R, Furgeson SB, Lu S, Kirkpatrick B, Cleveland JC, Nemenoff RA, Ambardekar AV, Weiser-Evans MC. PTEN deficiency promotes pathological vascular remodeling of human coronary arteries. JCI Insight. 2018 Feb 22;3(4). [Epub ahead of print] PubMed PMID: 29467331
• Montford JR, Lehman AMB, Bauer CD, Klawitter J, Klawitter J, Poczobutt JM, Scobey M, Weiser-Evans M, Nemenoff RA, Furgeson SB. Bone marrow-derived cPLA2a contributes to renal fibrosis progression. J Lipid Res. 2018 Feb;59(2):380-390. PubMed PMID: 29229740
• Montford JR, Furgeson SB. A new CTGF target in renal fibrosis. Kidney Int. 2017 Oct;92(4):784-786. PubMed PMID: 28938948
• Montford JR, Bauer C, Dobrinskikh E, Hopp K, Levi M, Weiser-Evans M, Nemenoff R, Furgeson SB. Inhibition of 5-lipoxygenase decreases renal fibrosis and progression of chronic kidney disease. Am J Physiol Renal Physiol. 2019 Apr 1;316(4):F732-F742. PubMed PMID: 30649890
• Lu S, Strand KA, Mutryn MF, Tucker RM, Jolly AJ, Furgeson SB, Moulton KS, Nemenoff RA, Weiser-Evans MCM. PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling. Arterioscler Thromb Vasc Biol. 2019 Dec 19;:ATVBAHA119313757. [Epub ahead of print] PubMed PMID: 31852223
• Lu S, Strand KA, Mutryn MF, Tucker RM, Jolly AJ, Furgeson SB, Moulton KS, Nemenoff RA, Weiser-Evans MCM. PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling-Brief Report. Arterioscler Thromb Vasc Biol. 2020 Feb;40(2):394-403. PubMed PMID: 31852223
• Natalie Beck, Seth Furgeson, Michel Chonchol and Jessica Kendrick. Internal Medicine Residents’ Perceptions of Nephrology as a Career: A Focus Group Study. Kidney360 October 2020, 1 (10) 1052-1059.
• Montford JR, Bauer C, Rahkola J, Reisz JA, Floyd D, Hopp K, Soranno DE, Klawitter J, Weiser-Evans MCM, Nemenoff R, Faubel S, Furgeson SB. 15-Lipoxygenase worsens renal fibrosis, inflammation, and metabolism in a murine model of ureteral obstruction. Am J Physiol Renal Physiol. 2022 Jan 1;322(1):F105-F119. PubMed PMID: 34866403
• Furgeson SB, Linas S. Chlorthalidone and Advanced Chronic Kidney Disease. Clin J Am Soc Nephrol. 2022 Jul;17(7):1076-1078. PubMed PMID: 35577563
• Montford JR, Bauer C, Rahkola J, Reisz JA, Floyd D, Hopp K, Soranno DE, Klawitter J, Weiser-Evans MCM, Nemenoff R, Faubel S, Furgeson SB. 15-Lipoxygenase worsens renal fibrosis, inflammation, and metabolism in a murine model of ureteral obstruction. Am J Physiol Renal Physiol. 2022 Jan 1;322(1):F105-F119. PubMed PMID: 34866403
• Kleczko EK, Nguyen DT, Marsh KH, Bauer CD, Li AS, Monaghan MT, Berger MD, Furgeson SB, Gitomer BY, Chonchol MB, Clambey ET, Zimmerman KA, Nemenoff RA, Hopp K. Immune checkpoint activity regulates polycystic kidney disease progression. JCI Insight. 2023 Jun 22;8(12). PubMed PMID: 37345660
• Lai J, Furgeson S, Bjornstad P, You Z, Tommerdahl KL, Kendrick J. Leukotriene Antagonist Use is Associated With Lower Systolic Blood Pressure in Adults. Kidney Int Rep. 2023 Feb;8(2):373-375. PubMed PMID: 36815112

Professional Memberships

• American Society of Nephrology, Member
• American College of Physicians (ACP), Member

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Denver Health
777 Bannock St
Denver, CO 80204
303-436-6000

Hospital Affiliation

• University of Colorado Hospital
• Denver Health Medical Center

Specialty Information

Specialties

• Internal Medicine, Board Certification (2005)
• Nephrology, Board Certification (2009)

Conditions & Treatments

• Kidneys and Urinary System - Kidney Disease
• Kidneys and Urinary System - Kidney Failure
• Kidneys and Urinary System - Nephrotic Syndrome
• Kidneys and Urinary System - Proteinuria
• Heart and Circulation - High Blood Pressure
• Heart and Circulation
• Kidneys and Urinary System