Lynn Heasley, PhD
Professor, School of Dental Medicine
Publications
- Winn, R.A., Marek, L., Han, S.Y., Rodriguez, K., Rodriguez, N., Hammond, M., Van Scoyk, M, Acosta, H., Mirus, J., Barry, N., Hurteau, G., Bren-Mattison, Y., Van Raay, T.J., Nemenoff, R.A., and Heasley, L.E. (2005) Restoration of Wnt-7a expression reverses non-small cell lung cancer cell transformation through frizzled-9 mediated growth inhibition and promotion of cellular differentiation. J. Biol. Chem. 280:19625-19634.
- Takada, E., Shimo, K., Hata, K., Abiake, M., Mukai, Y., Moriyama, M., Heasley, L., and Mizuguchi, J. (2005) Interferon-?-induced activation of c-Jun NH2-terminal kinase mediates apoptosis through upregulation of CD95 in CH31 B lymphoma cells. Exp Cell Res. 304:518-30.
- Abell, A.N., Rivera-Perez, J.A., Cuevas, B.D., Uhlik, M.T., Sather, S., Johnson, N.L., Minton, S.K., Lauder, J.M., Winter-Vann, A.M., Nakamura, K., Magnuson, T., Vaillancourt, R.R., Heasley, L.E. and Johnson, G.L. (2005) Ablation of MEKK4 kinase activity causes neurulation and skeletal patterning defects in the mouse embryo. Mol. Cell. Biol. 25:8948–8959.
- Amura, C., Marek, L., Winn, R.A. and Heasley, L.E. (2005) Inhibited neurogenesis in JNK1-deficient embryonic stem cells. Mol. Cell. Biol. 25:10791-10802.
- Han, S.Y., Marek, L., Mirus, M., Meyer, A., Hammond, M., Baron, A., and Zeng, C., Winn, R.A., Nemenoff, R.A. and Heasley, L.E. JNK1 and JNK2 negatively regulate lung tumorigenesis. Cancer Res., in press.
- Heasley, L.E. and Han, S.Y. JNK Regulation of Oncogenesis. Molecules and Cells, in press.
- Heasley, L.E. and Han, S.Y. (2006) JNK regulation of oncogenesis. Mol Cells 21:167-73.
- Winn, R.A., Van Scoyk, M., Hammond, M., Rodriguez, K., Crossno, J., Heasley, L.E., and Nemenoff, R.A. (2006) Antitumorigenic effect of Wnt 7a and Fzd 9 in non-small cell lung cancer cells is mediated through ERK-5 dependent activation of PPARg J. Biol. Chem. 281:26943-50.
- Binétruy, B., Heasley, L., Bost, F., Caron, L. and Aouadi, M. (2007) Regulation of ES cell lineage commitment by mitogen activated protein kinases. Stem Cells, in press.