Director of the Children’s Sleep Medicine Laboratory - Children's Hospital Colorado
Recognitions
Best Doctors in America, Best Doctors, Inc.
(2008)
Also awarded in (2007)
Honor Award, American Academy of Otolaryngology
(2008)
Publications
19. Friedman NR, Luck M, Scapa VI. Excision of congenital nasolacrimal duct cyst
with powered instrumentation. Laryngoscope. 2010 Aug 30. [Epub ahead of print] PubMed PMID: 20824646.
Burg CJ, Friedman NR. Diagnosis and treatment of sleep apnea in adolescents.
Adolesc Med State Art Rev. 2010 Dec;21(3):457-79, viii. Review. PubMed PMID:
21302855.
Roland PS, Rosenfeld RM, Brooks LJ, Friedman NR, Jones J, Kim TW, Kuhar S,
Mitchell RB, Seidman MD, Sheldon SH, Jones S, Robertson P; American Academy of Otolaryngology—Head and Neck Surgery Foundation. Clinical practice guideline: Polysomnography for sleep-disordered breathing prior to tonsillectomy in
children. Otolaryngol Head Neck Surg. 2011 Jul;145(1 Suppl):S1-15. Epub 2011 Jun
15. PubMed PMID: 21676944.
Zi Yang Jiang, Kevin D. Pereira, Norman R. Friedman, Ron B. Mitchell,Inferior Turbinate Surgery in Children: A Survey of Practice Patterns accepted Laryngoscope
Jonathan N. Perkins,Conan Liang, Dexiang Gao, PhD,,Lynn Shultz, Norman R. Friedman, Risk of Post-Tonsillectomy Hemorrhage by Clinical Diagnosis accepted Laryngoscope
Friedman NR: Novel methods to diagnose obstructive sleep apnea in children Operative Techniques in Otolaryngology. March 2012
Yoon P Kelley PE, Friedman NR,. Ear, Nose and Throat Chapter: Current Pediatrics Diagnosis and Treatment. Eds. Hay WW, Hayward AR, et al: 20 editions. Accepted
Friedman NR, Wetmore, Ralph Infant and Pediatric Apnea Pediatric Otolaryngology Principles and Practice Pathways 2nd Edition Thieme ( Ralph F. Wetmore, Harlan R. Muntz, and Trevor J. Mc Gill editors)
American Society of Pediatric Otolaryngology Webnair: Sleep Disordered Breathing: An Update
Perkins JN, Liang C, Gao D, Shultz L, Friedman NR. Risk of post-tonsillectomy hemorrhage by clinical diagnosis. Laryngoscope. 2012 Oct;122(10):2311-5. doi:10.1002/lary.23421. Epub 2012 Jul 9. PubMed PMID: 22778043
22. Friedman NR, Perkins JN, McNair B, Mitchell RB. Current practice patterns for sleep-disordered breathing in children. Laryngoscope. 2013 Feb 4. doi:10.1002/lary.23709. [Epub ahead of print] PubMed PMID: 23382017
13. Yoon PJ, Friedman NR, Kelley PE. Ear, Nose & Throat. In: Hay WW, et al., Eds. Current Pediatric Diagnosis and Treatment, 21st Edition. New York: Lange/McGraw Hill, 2012
Friedman NR. Pediatric sleep studies: when and how often are they necessary?
Curr Opin Otolaryngol Head Neck Surg. 2013 Dec;21(6):557-66. doi:
10.1097/MOO.0b013e328365ba8d. PubMed PMID: 24240132.
Friedman NR, Perkins JN, McNair B, Mitchell RB. Current practice patterns for
sleep-disordered breathing in children. Laryngoscope. 2013 Apr;123(4):1055-8.
doi: 10.1002/lary.23709. Epub 2013 Feb 4. PubMed PMID: 23382017.
Liang C, Ruiz AG, Jensen EL, Friedman NR. Indications, Clinical Course, and Postoperative Outcomes of Urgent Adenotonsillectomy in Children. JAMA Otolaryngol Head Neck Surg. 2015 Jan 2. [Epub ahead of print] PubMed PMID: 25555106
Chatterjee D, Friedman N, Shott S, Mahmoud M. Anesthetic dilemmas for dynamic evaluation of the pediatric upper airway. Semin Cardiothorac Vasc Anesth. 2014 Dec;18(4):371-8. PubMed PMID: 25172630
Ingram DG, Friedman NR. Toward Adenotonsillectomy in Children: A Review for the General Pediatrician. JAMA Pediatr. 2015 Oct 5;:1-8. [Epub ahead of print] PubMed PMID: 26436644
Friedman NR, Prager JD, Ruiz AG, Kezirian EJ. A Pediatric Grading Scale for Lingual Tonsil Hypertrophy. Otolaryngol Head Neck Surg. 2015 Aug 25. [Epub ahead of print] PubMed PMID: 26307581
Côté V, Ruiz AG, Perkins J, Sillau S, Friedman NR. Characteristics of children under 2 years of age undergoing tonsillectomy for upper airway obstruction. Int J Pediatr Otorhinolaryngol. 2015 Jun;79(6):903-8. PubMed PMID: 25912628
Ingram DG, Ruiz A, Friedman NR. Friedman tongue position: age distribution and relationship to sleep-disordered breathing. Int J Pediatr Otorhinolaryngol. 2015 May;79(5):666-70. PubMed PMID: 25736546
Liang C, Ruiz AG, Jensen EL, Friedman NR. Indications, clinical course, and postoperative outcomes of urgent adenotonsillectomy in children. JAMA Otolaryngol Head Neck Surg. 2015 Mar;141(3):236-44. PubMed PMID: 25555106
Friedman NR, Parikh SR, Ishman SL, Ruiz AG, El-Hakim H, Ulualp SO, Wootten CT, Koltai PJ, Chan DK. The current state of pediatric drug-induced sleep endoscopy. Laryngoscope. 2017 Jan;127(1):266-272. PubMed PMID: 27311407
Hawkins SM, Jensen EL, Simon SL, Friedman NR. Correlates of Pediatric CPAP Adherence. J Clin Sleep Med. 2016 Jun 15;12(6):879-84. PubMed PMID: 27092702
Nardone HC, McKee-Cole KM, Friedman NR. Current Pediatric Tertiary Care Admission Practices Following Adenotonsillectomy. JAMA Otolaryngol Head Neck Surg. 2016 May 1;142(5):452-6. PubMed PMID: 27010313
Friedman NR, Prager JD, Ruiz AG, Kezirian EJ. A Pediatric Grading Scale for Lingual Tonsil Hypertrophy. Otolaryngol Head Neck Surg. 2016 Jan;154(1):171-4. PubMed PMID: 26307581
Ingram DG, Friedman NR. Obstructive sleep apnea in children: Controversies in
Diagnosis and Management Int J Head and Neck Surg 2016:7(2)83-88.
Friedman NR, Ruiz AG, Gao D, Ingram DG. Accuracy of Parental Perception of Nighttime Breathing in Children with Down Syndrome. Otolaryngol Head Neck Surg. 2017 Sep 1;:194599817726286. [Epub ahead of print] PubMed PMID: 28871845
Ingram DG, Ruiz AG, Gao D, Friedman NR. Success of Tonsillectomy for Obstructive Sleep Apnea in Children With Down Syndrome. J Clin Sleep Med. 2017 Aug 15;13(8):975-980. PubMed PMID: 28728615
Friedman NR, Parikh SR, Ishman SL, Ruiz AG, El-Hakim H, Ulualp SO, Wootten CT, Koltai PJ, Chan DK. The current state of pediatric drug-induced sleep endoscopy. Laryngoscope. 2017 Jan;127(1):266-272. PubMed PMID: 27311407
Kirk V, Baughn J, D'Andrea L, Friedman N, Galion A, Garetz S, Hassan F, Wrede J, Harrod CG, Malhotra RK. American Academy of Sleep Medicine Position Paper for the Use of a Home Sleep Apnea Test for the Diagnosis of OSA in Children. J Clin Sleep Med. 2017 Oct 15;13(10):1199-1203. PubMed PMID: 28877820
Chan KH, Allen GC, Kelley PE, Streubel SO, Friedman NR, Yoon P, Gao D, Ruiz AG, Jung TTK. Dornase Alfa Ototoxic Effects in Animals and Efficacy in the Treatment of Clogged Tympanostomy Tubes in Children: A Preclinical Study and a Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2018 Sep 1;144(9):776-780. PubMed PMID: 30073253
Goldstein NA, Friedman NR, Nardone HC, Aljasser A, Tobey ABJ, Don D, Baroody FM, Lam DJ, Goudy S, Ishman SL, Arganbright JM, Baldassari C, Schreinemakers JBS, Wine TM, Ruszkay NJ, Alammar A, Shaffer AD, Koempel JA, Weedon J. The generalizability of the clinical assessment score-15 for pediatric sleep-disordered breathing. Laryngoscope. 2019 Nov 29. [Epub ahead of print] PubMed PMID: 31782808
Greenlee CJ, Scholes MA, Gao D, Friedman NR. Obstructive Sleep Apnea and Sleep Position: Does It Matter for Infants With a Cleft Palate?. Cleft Palate Craniofac J. 2019 Aug;56(7):890-895. PubMed PMID: 31282194
Ruiz AG, Gao D, Ingram DG, Hickey F, Haemer MA, Friedman NR. Does Tonsillectomy Increase Obesity Risk in Children with Down Syndrome?. J Pediatr. 2019 Aug;211:179-184.e1. PubMed PMID: 31084917
Obstructive Sleep Apnea and Sleep
Position: Does It Matter for Infants
With a Cleft Palate?
cleft palate and craniofacial journal
Friedman NR, Ruiz AG, Gao D, Jensen A, Mitchell RB. Pediatric Obstructive Sleep-Disordered Breathing: Updated Polysomnography Practice Patterns. Otolaryngol Head Neck Surg. 2019 Sep;161(3):529-535. PubMed PMID: 31035864
AAO/HNS revised clinical practice guideline for tonsillectomy
Mitchell RB, Archer SM, Ishman SL, Rosenfeld RM, Coles S, Finestone SA, Friedman NR, Giordano T, Hildrew DM, Kim TW, Lloyd RM, Parikh SR, Shulman ST, Walner DL, Walsh SA, Nnacheta LC. Clinical Practice Guideline: Tonsillectomy in Children (Update)-Executive Summary. Otolaryngol Head Neck Surg. 2019 Feb;160(2):187-205. PubMed PMID: 30921525
Mitchell RB, Archer SM, Ishman SL, Rosenfeld RM, Coles S, Finestone SA, Friedman NR, Giordano T, Hildrew DM, Kim TW, Lloyd RM, Parikh SR, Shulman ST, Walner DL, Walsh SA, Nnacheta LC. Clinical Practice Guideline: Tonsillectomy in Children (Update). Otolaryngol Head Neck Surg. 2019 Feb;160(1_suppl):S1-S42. PubMed PMID: 30798778
Chung MG, Guilliams KP, Wilson JL, Beslow LA, Dowling MM, Friedman NR, Hassanein SMA, Ichord R, Jordan LC, Mackay MT, Rafay MF, Rivkin M, Torres M, Zafeiriou D, deVeber G, Fox CK. Arterial Ischemic Stroke Secondary to Cardiac Disease in Neonates and Children. Pediatr Neurol. 2019 Nov;100:35-41. PubMed PMID: 31371125
Scholes M, Jensen E, Meier M, Friedman N. Effect of adenotonsillectomy in children with obstructive sleep apnea and major psychiatric disorders on obstructive apnea-hypopnea index and Epworth Sleepiness Scale scores. J Clin Sleep Med. 2020 Nov 18. [Epub ahead of print] PubMed PMID: 33206042
Goldstein NA, Friedman NR, Nardone HC, Aljasser A, Tobey ABJ, Don D, Baroody FM, Lam DJ, Goudy S, Ishman SL, Arganbright JM, Baldassari C, Schreinemakers JBS, Wine TM, Ruszkay NJ, Alammar A, Shaffer AD, Koempel JA, Weedon J. The Generalizability of the Clinical Assessment Score-15 for Pediatric Sleep-Disordered Breathing. Laryngoscope. 2020 Sep;130(9):2256-2262. PubMed PMID: 31782808
Tholen K, Meier M, Kloor J, Friedman N. Persistent OSA in obese children: does body position matter?. J Clin Sleep Med. 2020 Oct 23. [Epub ahead of print] PubMed PMID: 33094724
Bootpetch TC, Hafrén L, Elling CL, Baschal EE, Manichaikul AW, Pine HS, Szeremeta W, Scholes MA, Cass SP, Larson ED, Chan KH, Ishaq R, Prager JD, Shaikh RS, Gubbels SP, Yousaf A, Wine TM, Bamshad MJ, Yoon PJ, Jenkins HA, Nickerson DA, Streubel SO, Friedman NR, Frank DN, Einarsdottir E, Kere J, Riazuddin S, Daly KA, Leal SM, Ryan AF, Mattila PS, Ahmed ZM, Sale MM, Chonmaitree T, Santos-Cortez RLP. Multi-omic studies on missense PLG variants in families with otitis media. Sci Rep. 2020 Sep 14;10(1):15035. PubMed PMID: 32929111
Benedek P, Balakrishnan K, Cunningham MJ, Friedman NR, Goudy SL, Ishman SL, Katona G, Kirkham EM, Lam DJ, Leboulanger N, Lee GS, Le Treut C, Mitchell RB, Muntz HR, Musso MF, Parikh SR, Rahbar R, Roy S, Russell J, Sidell DR, Sie KCY, Smith RJ, Soma MA, Wyatt ME, Zalzal G, Zur KB, Boudewyns A. International Pediatric Otolaryngology group (IPOG) consensus on the diagnosis and management of pediatric obstructive sleep apnea (OSA). Int J Pediatr Otorhinolaryngol. 2020 Nov;138:110276. PubMed PMID: 32810686
Hines S, Pickett K, Tholen K, Handley E, Friedman NR. Tonsillectomy Outcomes for Children With Severe Obesity. Laryngoscope. 2021 Jun 30. [Epub ahead of print] PubMed PMID: 34191279
Virbalas J, Friedman NR. Impact of neck CT on the management of suspected pediatric deep neck space infection. Int J Pediatr Otorhinolaryngol. 2021 Aug;147:110782. PubMed PMID: 34038853
Vielkind M, Wolter-Warmerdam K, Jackson A, Maybee J, Brown M, Friedlander J, Friedman N, Hickey F, Prager J, Wine T, DeBoer E. Airway obstruction and inflammation on combined bronchoscopy in children with Down syndrome. Pediatr Pulmonol. 2021 Sep;56(9):2932-2939. PubMed PMID: 34245494
Jensen AM, Herrmann BW, Mitchell RB, Friedman NR. Growth After Adenotonsillectomy for Obstructive Sleep Apnea: Revisited. Laryngoscope. 2021 Sep 22. [Epub ahead of print] PubMed PMID: 34551129
Lackey TG, Tholen K, Pickett K, Friedman N. Residual OSA in Down syndrome: does body position matter?. J Clin Sleep Med. 2022 Sep 9. [Epub ahead of print] PubMed PMID: 36081330
Friedman NR, Meier M, Tholen K, Crowder R, Hoefner-Notz R, Nguyen T, Derieg S, Campbell K, McLeod L. Tonsillectomy for Obstructive Sleep-Disordered Breathing: Should They Stay, or Could They Go?. Laryngoscope. 2021 Oct 21. [Epub ahead of print] PubMed PMID: 34672364
Friedman NR, Green KK. Upper Airway Stimulation for Children With Down Syndrome and Obstructive Sleep Apnea-A New Frontier. JAMA Otolaryngol Head Neck Surg. 2022 Jun 1;148(6):529-530. PubMed PMID: 35446405
Herrmann BW, Campbell K, Meier M, Haemer M, Crowder R, Tholen K, Hoefner-Notz R, Nguyen T, Friedman NR. Parental Perception of Weight Status for Adenotonsillectomy Patients. Laryngoscope. 2021 Sep;131(9):2121-2125. PubMed PMID: 33569790
Friedman NR, Meier M, Tholen K, Crowder R, Hoefner-Notz R, Nguyen T, Derieg S, Campbell K, McLeod L. Tonsillectomy for Obstructive Sleep-Disordered Breathing: Should They Stay, or Could They Go?. Laryngoscope. 2022 Aug;132(8):1675-1681. PubMed PMID: 34672364
Jensen AM, Herrmann BW, Mitchell RB, Friedman NR. Growth After Adenotonsillectomy for Obstructive Sleep Apnea: Revisited. Laryngoscope. 2022 Jun;132(6):1289-1294. PubMed PMID: 34551129
Mooney KL, Brooks Peterson M, Skirko JR, Friedman NR. The Quest for a DISE Protocol. Otolaryngol Head Neck Surg. 2021 Aug 17;:1945998211036645. [Epub ahead of print] PubMed PMID: 34399647
Mooney KL, Brooks Peterson M, Skirko JR, Friedman NR. The Quest for a DISE Protocol. Otolaryngol Head Neck Surg. 2022 Sep;167(3):590-599. PubMed PMID: 34399647
Hines S, Pickett K, Tholen K, Handley E, Friedman NR. Tonsillectomy Outcomes for Children With Severe Obesity. Laryngoscope. 2022 Feb;132(2):461-469. PubMed PMID: 34191279
Tholen K, Meier M, Kloor J, Friedman N. Persistent OSA in obese children: does body position matter?. J Clin Sleep Med. 2021 Feb 1;17(2):227-232. PubMed PMID: 33094724
Duis J, Pullen LC, Picone M, Friedman N, Hawkins S, Sannar E, Pfalzer AC, Shelton AR, Singh D, Zee PC, Glaze DG, Revana A. Diagnosis and management of sleep disorders in Prader-Willi syndrome. J Clin Sleep Med. 2022 Jun 1;18(6):1687-1696. doi: 10.5664/jcsm.9938. PMID: 35172921; PMCID: PMC9163612.
Norman R. Friedman, MD, Pediatric Adenotonsillar Disease and Obstructive Sleep-Disordered Breathing, ENT Secrets 5th Edition, Chapter 51, Elservier 2022
Chan KH, Thomas BJ, Gilbert DD, Tong S, Teynor NJ, Friedman NR, Herrmann BW, Gitomer SA. Olfactory dysfunction and training in children with COVID-19 infection: A prospective study Post-COVID pediatric olfactory training. Int J Pediatr Otorhinolaryngol. 2023 Nov 23;176:111799. [Epub ahead of print] PubMed PMID: 38081110
Friedman NR. Adenotonsillectomy for Treatment of Mild Sleep-Disordered Breathing in Children. JAMA Otolaryngol Head Neck Surg. 2023 Dec 5. [Epub ahead of print] PubMed PMID: 38051526
Goff SH, Pickett-Nairne K, Nguyen T, Rove KO, Friedman NR. The Effect of Social Vulnerability on Perioperative Tonsillectomy Outcomes in Children. Laryngoscope. 2023 Nov 16. [Epub ahead of print] PubMed PMID: 37971081
Pham TT, Davis SM, Tong S, Campa KA, Friedman NR, Gitomer SA. High Prevalence of Obstructive Sleep-Disordered Breathing in Pediatric Patients With Turner Syndrome. Otolaryngol Head Neck Surg. 2023 Nov 8. [Epub ahead of print] PubMed PMID: 37937707
Chabuz CA, Lackey TG, Pickett KL, Friedman NR. Accuracy of parental perception of nighttime breathing in children with Down syndrome after adenotonsillectomy. J Clin Sleep Med. 2023 Oct 3. [Epub ahead of print] PubMed PMID: 37858282
Lam DJ, Friedman NR, Chan KC, Kirkham EM, Smith DF, Benedek P, Boudewyns A. Development and validation of the international pediatric sleep endoscopy scale (IPSES). Int J Pediatr Otorhinolaryngol. 2023 Nov;174:111748. PubMed PMID: 37820572
Kashiwazaki R, Jensen AM, Haemer M, Friedman NR. The Effects of Adenotonsillectomy for Obstructive Sleep Apnea on Growth Trajectory in Children With Obesity. Otolaryngol Head Neck Surg. 2023 Sep 5. [Epub ahead of print] PubMed PMID: 37668178
Parikh SR, Boudewyns A, Friedman NR, Schwartz SR, Baldassari CM, Benedek P, Carr MM, Chan DK, Chan KC, Cheng AT, Couloigner V, Diala OR, DeRowe A, El-Hakim H, Fayoux P, Hsu WC, Ishman S, Kirkham EM, Mitchell RB, Thevasagayam R, Lam D. International Pediatric Otolaryngology Group (IPOG) consensus on scoring of pediatric Drug Induced Sleep Endoscopy (DISE). Int J Pediatr Otorhinolaryngol. 2023 Aug;171:111627. PubMed PMID: 37441992
Lackey TG, Tholen K, Pickett K, Friedman N. Residual OSA in Down syndrome: does body position matter?. J Clin Sleep Med. 2023 Jan 1;19(1):171-177. PubMed PMID: 36081330
Friedman NR, Nguyen T, McLeod L. In Reference to "Tonsillectomy for Obstructive Sleep-Disordered Breathing: Should They Stay, or Could They Go?". Laryngoscope. 2023 Sep;133(9):E55-E56. PubMed PMID: 36912387
Current Pediatric Tertiary Care Practices Following Adenotonsillectomy: An Update
Annie E. Moroco MD, Norman Friedman MD, Christopher Jabbour MD, Soham Roy MD, Richard Schmidt MD, Heather C. Nardone MD
First published: 10 December 2023
https://doi.org/10.1002/lary.31216
Friedman NR. Adenotonsillectomy for Treatment of Mild Sleep-Disordered Breathing in Children. JAMA Otolaryngol Head Neck Surg. Published online December 05, 2023. doi:10.1001/jamaoto.2023.3808
Lackey TG, Rowley J, Pham TT, Portnuff CD, Ramos L, Friedman NR, Herrmann BW. Do Surgical Smoke Evacuators Increase the Risk of Hearing Loss for Operative Personnel During Routine Adenotonsillectomy Surgery?. Cureus. 2024 May;16(5):e60214. PubMed PMID: 38868294
Chieffe D, Baldassari CM, Friedman N, Smith D, Heubi C, Hartnick C. Pediatric Down Syndrome Upper Airway Stimulation: Patient Selection and Post-Implantation Optimization. Otolaryngol Head Neck Surg. 2024 Apr;170(4):1158-1166. PubMed PMID: 38169046
Diala OR, Polat P, Pickett-Nairne K, Friedman NR. Longitudinal Success of Tonsillectomy for Obstructive Sleep Apnea in Children with Down Syndrome. Otolaryngol Head Neck Surg. 2024 Jul 21. [Epub ahead of print] PubMed PMID: 39033353
Santos-Cortez RLP, Gomez HZ, Elling CL, Mayher L, Diala OR, Gardner C, Willford K, Zamora VC, Agyepong A, Lee NK, Green KK, Darr OA, Wine TM, Francom CR, Larson ED, Gitomer SA, Schell AE, Frank DN, Friedman NR, Herrmann BW. APOBR Is Downregulated in EBV Tonsils of Children with Obstructive Sleep-Disordered Breathing. Genes (Basel). 2024 Oct 14;15(10). PubMed PMID: 39457448
Jáuregui EJ, Diala O, Rove KO, Hoefner-Notz R, Tong S, Nguyen T, Friedman NR. Overnight Monitoring Criteria for Children with Obstructive Sleep-Disordered Breathing After Tonsillectomy: Revisited. Laryngoscope. 2024 Dec;134(12):5223-5230. PubMed PMID: 39031661