Kathleen Waugh, MS
Sr. Research Instructor, Pediatrics-Barbara Davis Center
Professional Titles
- Research Instructor
Publications
- Liu CW, Bramer L, Webb-Robertson BJ, Waugh K, Rewers MJ, Zhang Q. Temporal expression profiling of plasma proteins reveals oxidative stress in early stages of Type 1 Diabetes progression. J Proteomics. 2018; 172:100-110.
- Steck AK, Dong F, Frohnert BI, Waugh K, Hoffman M, Norris JM, Rewers MJ. Predicting progression to diabetes in islet autoantibody positive children. J Autoimmun. 2018;90:59-63.
- Lund-Blix NA, Dong F, Mårild K, Seifert J, Barón AE, Waugh KC, Joner G, Størdal K, Tapia G, Stene LC, Johnson RK, Rewers MJ, Norris JM. Gluten Intake and Risk of Islet Autoimmunity and Progression to Type 1 Diabetes in Children at Increased Risk of the Disease: The Diabetes Autoimmunity Study in the Young (DAISY). Diabetes Care. 2019 May;42(5):789-796. PubMed PMID: 30796108
- Mårild K, Dong F, Lund-Blix NA, Seifert J, Barón AE, Waugh KC, Taki I, Størdal K, Tapia G, Stene LC, Johnson RK, Liu E, Rewers MJ, Norris JM. Gluten Intake and Risk of Celiac Disease: Long-Term Follow-up of an At-Risk Birth Cohort. Am J Gastroenterol. 2019 Aug;114(8):1307-1314. PubMed PMID: 31082869
- Gu Y, Zhao Z, Waugh K, Miao D, Jia X, Cheng J, Michels A, Rewers M, Yang T, Yu L. High-throughput multiplexed autoantibody detection to screen type 1 diabetes and multiple autoimmune diseases simultaneously. EBioMedicine. 2019 Sep;47:365-372. PubMed PMID: 31447394
- Frohnert BI, Webb-Robertson BJ, Bramer LM, Reehl SM, Waugh K, Steck AK, Norris JM, Rewers M. Predictive Modeling of Type 1 Diabetes Stages Using Disparate Data Sources. Diabetes. 2019 Nov 18. [Epub ahead of print] PubMed PMID: 31740441
- Johnson RK, Vanderlinden LA, Dong F, Carry PM, Seifert J, Waugh K, Shorrosh H, Fingerlin T, Frohnert BI, Yang IV, Kechris K, Rewers M, Norris JM. Longitudinal DNA methylation differences precede type 1 diabetes. Sci Rep. 2020 Feb 28;10(1):3721. PubMed PMID: 32111940
- Buckner T, Vanderlinden LA, Johnson RK, DeFelice BC, Carry PM, Seifert J, Waugh K, Dong F, Fiehn O, Clare-Salzler M, Rewers M, Norris JM. Predictors of oxylipins in a healthy pediatric population. Pediatr Res. 2020 Jul 29. [Epub ahead of print] PubMed PMID: 32726799
- Stahl MG, Dong F, Lamb MM, Waugh KC, Taki I, Størdal K, Stene LC, Rewers MJ, Liu E, Norris JM, Mårild K. Childhood growth prior to screen-detected celiac disease: prospective follow-up of an at-risk birth cohort. Scand J Gastroenterol. 2020 Nov;55(11):1284-1290. PubMed PMID: 32941083
- Onengut-Gumuscu S, Paila U, Chen W, Ratan A, Zhu Z, Steck AK, Frohnert BI, Waugh K, Webb-Robertson BJ, Norris JM, Lange LA, Rewers M, Rich SS. Novel genetic risk factors influence progression of islet autoimmunity to type 1 diabetes. Scientific Reports 2020 Nov 5;10(1):19193. PMID: 33154504 PMCID: PMC7645414.
- McQueen RB, Geno Rasmussen C, Waugh K, Frohnert BI, Steck AK, Yu L, Baxter J, Rewers M. Cost and Cost-effectiveness of Large-scale Screening for Type 1 Diabetes in Colorado. Diabetes Care. 2020 Jul;43(7):1496-1503. PubMed PMID: 32327420
- Stahl MG, Geno Rasmussen C, Dong F, Waugh K, Norris JM, Baxter J, Yu L, Steck AK, Frohnert BI, Liu E, Rewers MJ. Mass Screening for Celiac Disease: The Autoimmunity Screening for Kids Study. Am J Gastroenterol. 2020 Jul 22. [Epub ahead of print] PubMed PMID: 32701732
- Ng K, Stavropoulos H, Anand V, Veijola R, Toppari J, Maziarz M, Lundgren M, Waugh K, Frohnert BI, Martin F, Hagopian W, Achenbach P. Islet Autoantibody Type-Specific Titer Thresholds Improve Stratification of Risk of Progression to Type 1 Diabetes in Children. Diabetes Care. 2021 Nov 10. [Epub ahead of print] PubMed PMID: 34758977
- Buckner T, Vanderlinden LA, Johnson RK, DeFelice BC, Carry PM, Seifert J, Waugh K, Dong F, Fiehn O, Clare-Salzler M, Rewers M, Norris JM. Predictors of oxylipins in a healthy pediatric population. Pediatr Res. 2021 May;89(6):1530-1540. PubMed PMID: 32726799
- Stahl MG, Geno Rasmussen C, Dong F, Waugh K, Norris JM, Baxter J, Yu L, Steck AK, Frohnert BI, Liu E, Rewers MJ. Mass Screening for Celiac Disease: The Autoimmunity Screening for Kids Study. Am J Gastroenterol. 2021 Jan 1;116(1):180-187. PubMed PMID: 32701732
- Mitchell AM, Alkanani AA, McDaniel KA, Pyle L, Waugh K, Steck AK, Nakayama M, Yu L, Gottlieb PA, Rewers MJ, Michels AW. T-cell responses to hybrid insulin peptides prior to type 1 diabetes development. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6). PubMed PMID: 33542101
- Jia X, He L, Miao D, Waugh K, Rasmussen CG, Dong F, Steck AK, Rewers M, Yu L. High-affinity ZnT8 Autoantibodies by Electrochemiluminescence Assay Improve Risk Prediction for Type 1 Diabetes. J Clin Endocrinol Metab. 2021 Nov 19;106(12):3455-3463. PubMed PMID: 34343303
- Tran PMH, Dong F, Kim E, Richardson KP, Tran LKH, Waugh K, Hopkins D, Cummings RD, Wang PG, Rewers MJ, She JX, Purohit S. Use of a glycomics array to establish the anti-carbohydrate antibody repertoire in type 1 diabetes. Nat Commun. 2022 Nov 1;13(1):6527. PubMed PMID: 36316364
- Mitchell AM, Baschal EE, McDaniel KA, Simmons KM, Pyle L, Waugh K, Steck AK, Yu L, Gottlieb PA, Rewers MJ, Nakayama M, Michels AW. Temporal development of T cell receptor repertoires during childhood in health and disease. JCI Insight. 2022 Sep 22;7(18). PubMed PMID: 35998036
- Ng K, Anand V, Stavropoulos H, Veijola R, Toppari J, Maziarz M, Lundgren M, Waugh K, Frohnert BI, Martin F, Lou O, Hagopian W, Achenbach P. Quantifying the utility of islet autoantibody levels in the prediction of type 1 diabetes in children. Diabetologia. 2022 Oct 5. [Epub ahead of print] PubMed PMID: 36195673
- Steck AK, Dong F, Geno Rasmussen C, Bautista K, Sepulveda F, Baxter J, Yu L, Frohnert BI, Rewers MJ, Rewers M, Barbour A, Bautista K, Baxter J, Felipe-Morales D, Dong F, Dormond-Brooks P, Driscoll K, Frohnert B, Rasmussen CG, Gesualdo P, Hoffman M, Karban R, Sepulveda F, Shorrosh H, Simmons K, Steck A, Taki I, Waugh K, Yu L, Liu E, Gallant M, McQueen RB, Norris JM. CGM Metrics Predict Imminent Progression to Type 1 Diabetes: Autoimmunity Screening for Kids (ASK) Study. Diabetes Care. 2022 Feb 1;45(2):365-371. PubMed PMID: 34880069
- Snell-Bergeon J, Waugh K, Dong F, Steck A, Norris J, Rewers M. Physical activity and progression to type 1 diabetes in children and youth with islet autoimmunity: The diabetes autoimmunity study in the young. Pediatr Diabetes. 2022 Jun;23(4):462-468. PubMed PMID: 35142009
- He L, Jia X, Rasmussen CG, Waugh K, Miao D, Dong F, Frohnert B, Steck AK, Simmons KM, Rewers M, Yu L. High-Throughput Multiplex Electrochemiluminescence Assay Applicable to General Population Screening for Type 1 Diabetes and Celiac Disease. Diabetes Technol Ther. 2022 Jul;24(7):502-509. PubMed PMID: 35238620
- Li Z, Veijola R, Koski E, Anand V, Martin F, Waugh K, Hyöty H, Winkler C, Killian MB, Lundgren M, Ng K, Maziarz M, Toppari J. Childhood Height Growth Rate Association With the Risk of Islet Autoimmunity and Development of Type 1 Diabetes. J Clin Endocrinol Metab. 2022 May 17;107(6):1520-1528. PubMed PMID: 35244713
- Ng K, Stavropoulos H, Anand V, Veijola R, Toppari J, Maziarz M, Lundgren M, Waugh K, Frohnert BI, Martin F, Hagopian W, Achenbach P. Islet Autoantibody Type-Specific Titer Thresholds Improve Stratification of Risk of Progression to Type 1 Diabetes in Children. Diabetes Care. 2022 Jan 1;45(1):160-168. PubMed PMID: 34758977
- Carry PM, Waugh K, Vanderlinden LA, Johnson RK, Buckner T, Rewers M, Steck AK, Yang I, Fingerlin TE, Kechris K, Norris JM. Changes in the Coexpression of Innate Immunity Genes During Persistent Islet Autoimmunity Are Associated With Progression of Islet Autoimmunity: Diabetes Autoimmunity Study in the Young (DAISY). Diabetes. 2022 Sep 1;71(9):2048-2057. PubMed PMID: 35724268
- Liebhoff AM, Venkataraman T, Morgenlander WR, Na M, Kula T, Waugh K, Morrison C, Rewers M, Longman R, Round J, Elledge S, Ruczinski I, Langmead B, Larman HB. Efficient encoding of large antigenic spaces by epitope prioritization with Dolphyn. bioRxiv. 2023 Jul 31. PubMed PMID: 37577562
- Webb-Robertson BM, Nakayasu ES, Dong F, Waugh KC, Flores J, Bramer LM, Schepmoes A, Gao Y, Fillmore T, Onengut-Gumuscu S, Frazer-Abel A, Rich SS, Holers VM, Metz TO, Rewers MJ. Decrease in multiple complement protein levels is associated with the development of islet autoimmunity and type 1 diabetes. medRxiv. 2023 Jul 16. PubMed PMID: 37502972
- Elhassan S, Dong F, Buckner T, Johnson RK, Seifert JA, Carry PM, Vanderlinden L, Waugh K, Rewers M, Norris JM. Investigating iron intake in risk of progression from islet autoimmunity to type 1 diabetes: The diabetes autoimmunity study in the young. Front Immunol. 2023;14:1124370. PubMed PMID: 37056761
- Tran PMH, Dong F, Kim E, Richardson KP, Tran LKH, Waugh K, Hopkins D, Cummings RD, Wang PG, Rewers MJ, She JX, Purohit S. Use of a glycomics array to establish the anti-carbohydrate antibody repertoire in type 1 diabetes. Nat Commun. 2022 Nov 1;13(1):6527. PubMed PMID: 36316364
- Ng K, Anand V, Stavropoulos H, Veijola R, Toppari J, Maziarz M, Lundgren M, Waugh K, Frohnert BI, Martin F, Lou O, Hagopian W, Achenbach P. Quantifying the utility of islet autoantibody levels in the prediction of type 1 diabetes in children. Diabetologia. 2023 Jan;66(1):93-104. PubMed PMID: 36195673
- Mitchell AM, Baschal EE, McDaniel KA, Simmons KM, Pyle L, Waugh K, Steck AK, Yu L, Gottlieb PA, Rewers MJ, Nakayama M, Michels AW. Temporal development of T cell receptor repertoires during childhood in health and disease. JCI Insight. 2022 Sep 22;7(18). PubMed PMID: 35998036
- Carry PM, Waugh K, Vanderlinden LA, Johnson RK, Buckner T, Rewers M, Steck AK, Yang I, Fingerlin TE, Kechris K, Norris JM. Changes in the Coexpression of Innate Immunity Genes During Persistent Islet Autoimmunity Are Associated With Progression of Islet Autoimmunity: Diabetes Autoimmunity Study in the Young (DAISY). Diabetes. 2022 Sep 1;71(9):2048-2057. PubMed PMID: 35724268
- Li Z, Veijola R, Koski E, Anand V, Martin F, Waugh K, Hyöty H, Winkler C, Killian MB, Lundgren M, Ng K, Maziarz M, Toppari J. Childhood Height Growth Rate Association With the Risk of Islet Autoimmunity and Development of Type 1 Diabetes. J Clin Endocrinol Metab. 2022 May 17;107(6):1520-1528. PubMed PMID: 35244713
- He L, Jia X, Rasmussen CG, Waugh K, Miao D, Dong F, Frohnert B, Steck AK, Simmons KM, Rewers M, Yu L. High-Throughput Multiplex Electrochemiluminescence Assay Applicable to General Population Screening for Type 1 Diabetes and Celiac Disease. Diabetes Technol Ther. 2022 Jul;24(7):502-509. PubMed PMID: 35238620
- Snell-Bergeon J, Waugh K, Dong F, Steck A, Norris J, Rewers M. Physical activity and progression to type 1 diabetes in children and youth with islet autoimmunity: The diabetes autoimmunity study in the young. Pediatr Diabetes. 2022 Jun;23(4):462-468. PubMed PMID: 35142009
- Monaco DR, Kottapalli SV, Breitwieser FP, Anderson DE, Wijaya L, Tan K, Chia WN, Kammers K, Caturegli P, Waugh K, Roederer M, Petri M, Goldman DW, Rewers M, Wang LF, Larman HB. Deconvoluting virome-wide antibody epitope reactivity profiles. EBioMedicine. 2022 Jan;75:103747. PubMed PMID: 34922324
- Ng K, Stavropoulos H, Anand V, Veijola R, Toppari J, Maziarz M, Lundgren M, Waugh K, Frohnert BI, Martin F, Hagopian W, Achenbach P. Islet Autoantibody Type-Specific Titer Thresholds Improve Stratification of Risk of Progression to Type 1 Diabetes in Children. Diabetes Care. 2022 Jan 1;45(1):160-168. PubMed PMID: 34758977