Moyed Miften, PhD
Professor, Radiation Oncology

Professional Titles

• Professor and Director, Medical Physics Division

Recognition & Awards

• Radiotherapy Technical Expert, IAEA (2016)
• Volunteer Service Award, American Board of Radiology (2014)
• Fellow, American Association of Physicists in Medicine (AAPM) (2011)
• Chancellor, Board of Chancellors, American College of Medical Physics (2011)

Teaching

Publications

• Vinogradskiy Y, Castillo R, Castillo E, Schubert L, Jones BL, Faught A, Gaspar LE, Kwak J, Bowles DW, Waxweiler T, Dougherty JM, Gao D, Stevens C, Miften M, Kavanagh B, Grills I, Rusthoven CG, Guerrero T. Results of a Multi-Institutional Phase 2 Clinical Trial for 4DCT-Ventilation Functional Avoidance Thoracic Radiation Therapy. Int J Radiat Oncol Biol Phys. 2022 Mar 15;112(4):986-995. PubMed PMID: 34767934
• Bayat F, Eldib ME, Kavanagh B, Miften M, Altunbas C. Concurrent kilovoltage CBCT imaging and megavoltage beam delivery: suppression of cross-scatter with 2D antiscatter grids and grid-based scatter sampling. Phys Med Biol. 2022 Aug 9;67(16). PubMed PMID: 35853441
• Zhu TC, Stathakis S, Clark JR, Feng W, Georg D, Holmes SM, Kry SF, Charlie Ma CM, Miften M, Mihailidis D, Moran JM, Papanikolaou N, Poppe B, Xiao Y. Erratum: "Report of AAPM Task Group 219 on independent calculation-based dose/MU verification for IMRT". Med Phys. 2022 Aug;49(8):5713. PubMed PMID: 35833598
• Ohri N, Tomé WA, Romero AM, Miften M, Haken RKT, Dawson LA, Grimm J, Yorke E, Jackson A. In Reply to Tsurugai et al. Int J Radiat Oncol Biol Phys. 2022 May 1;113(1):229. PubMed PMID: 35427548
• Zakem SJ, Jones B, Castillo R, Castillo E, Miften M, Goodman KA, Schefter T, Olsen J, Vinogradskiy Y. Cardiac metabolic changes on (18) F-positron emission tomography after thoracic radiotherapy predict for overall survival in esophageal cancer patients. J Appl Clin Med Phys. 2022 Mar 4;:e13552. [Epub ahead of print] PubMed PMID: 35243772
• Vinogradskiy Y, Castillo R, Castillo E, Schubert L, Jones BL, Faught A, Gaspar LE, Kwak J, Bowles DW, Waxweiler T, Dougherty JM, Gao D, Stevens C, Miften M, Kavanagh B, Grills I, Rusthoven CG, Guerrero T. Results of a Multi-Institutional Phase 2 Clinical Trial for 4DCT-Ventilation Functional Avoidance Thoracic Radiation Therapy. Int J Radiat Oncol Biol Phys. 2022 Mar 15;112(4):986-995. PubMed PMID: 34767934
• Pneumonitis Prediction Modeling of a Prospective 4DCT-Ventilation Functional Avoidance Clinical Trial Nourzadeh, H. et al. International Journal of Radiation Oncology, Biology, Physics, Volume 114, Issue 3, S60 - S6 (2022).
• Radiation (RT)-Associated Kidney Injury in Pediatric Cancer Patients: Results from the Pediatric Normal Tissue Effects in the Clinical (PENTEC) Genitourinary (GU) Task Force Poppe, M.M. et al. International Journal of Radiation Oncology, Biology, Physics, Volume 114, Issue 3, S71 (2022).
• Pulmonary Function Test Results for Patients Treated on a Two-Institution, 4DCT-Ventilation Functional Avoidance Prospective Clinical Trial Miller, R.C. et al. International Journal of Radiation Oncology, Biology, Physics, Volume 114, Issue 3, S86 - S87 (2022).
• Evaluation of Variables Predicting Pulmonary Function Test (PFT) Changes for Lung Cancer Patients Treated On a Prospective 4DCT-Ventilation Functional Avoidance Clinical Trial N Ghassemi et al. Med Phys (2022).
• A Novel Model for Characterizing the Effects of Gantry Flex On 2D Antiscatter Grid Performance in CBCT Systems M Eldib et al. Med. Phys. (2022).
• A Raw Data Correction and Iterative Reconstruction Pipeline for Quantitative CBCT-Guided Radiation Therapy Bayat et al. Med. Phys. (2022).
• Does Lung Function Imaging Modality Have a Dosimetric Impact On Functional Avoidance Treatment Planning: Assessment Using Prospective Clinical Trial Data Belardo et al. Med. Phys. (2022).
• A Simulation Platform to Evaluate the Effect of 2D Antiscatter Grid Primary Transmission On CBCT Image Quality Eldib et al. Med. Phys. (2022).
• AAPM IMRT QA Specialty Meeting: Learning From our Past to Move Patient Safety Forward, “Guidance for Measurement-Based Methods,”
• 2022 Radiation in Medicine Meeting, Riyadh, Saudi Arabia, “Treatment Planning System Quality Assurance,”.
• 2022 Radiation in Medicine Meeting, Riyadh, Saudi Arabia, “Patient Specific QA Workshop,”
• Sun Nuclear 2022 QA and Dosimetry Symposium, Enhancing Safety and Advancing QA, “Point/Counterpoint: Pretreatment Patient-Specific QA Measurements Should Be Replaced with In Vivo Dosimetry Techniques, Part I,”
• University of Toledo Medical Department and Medical Physics Graduate Program, “TG-218: Tolerance Limits and Methodologies for IMRT QA,”
• Zhu TC, Stathakis S, Clark JR, Feng W, Georg D, Holmes SM, Kry SF, Ma CC, Miften M, Mihailidis D, Moran JM, Papanikolaou N, Poppe B, Xiao Y. Report of AAPM Task Group 219 on independent calculation-based dose/MU verification for IMRT. Med Phys. 2021 Oct;48(10):e808-e829. PubMed PMID: 34213772
• Forghani F, Patton T, Kwak J, Thomas D, Diot Q, Rusthoven C, Castillo R, Castillo E, Grills I, Guerrero T, Miften M, Vinogradskiy Y. Characterizing spatial differences between SPECT-ventilation and SPECT-perfusion in patients with lung cancer undergoing radiotherapy. Radiother Oncol. 2021 Jul;160:120-124. PubMed PMID: 33964328
• Park Y, Alexeev T, Miller B, Miften M, Altunbas C. Evaluation of scatter rejection and correction performance of 2D antiscatter grids in cone beam computed tomography. Med Phys. 2021 Apr;48(4):1846-1858. PubMed PMID: 33554377
• Nitin Ohri, Wolfgang A Tomé, Alejandra Méndez Romero, Moyed Miften, Randall K Ten Haken, Laura Dawson, Jimm Grimm, Ellen Yorke, Andrew Jackson. In Reply to Klement et al. Int J Radiat Oncol Biol Phys . 2021 May 1;110(1):250-251.
• Schubert LK, Hendrickson K, Miften M, McNulty M, Vinogradskiy YY, Thomas DH, Westerly D, Stuhr K, Corral J, Royer D. The Current State of Physics Plan Review Training in Medical Physics Residency Programs in North America. Pract Radiat Oncol. 2020 May - Jun;10(3):e166-e172. PubMed PMID: 31526898
• Forghani F, Mahl A, Patton TJ, Jones BL, Borden MA, Westerly DC, Altunbas C, Miften M, Thomas DH. Simulation of x-ray-induced acoustic imaging for absolute dosimetry: Accuracy of image reconstruction methods. Med Phys. 2020 Mar;47(3):1280-1290. PubMed PMID: 31828781
• Vinogradskiy Y, Diot Q, Jones B, Castillo R, Castillo E, Kwak J, Bowles D, Grills I, Myziuk N, Guerrero T, Stevens C, Schefter T, Gaspar LE, Kavanagh B, Miften M, Rusthoven C. Evaluating Positron Emission Tomography-Based Functional Imaging Changes in the Heart After Chemo-Radiation for Patients With Lung Cancer. Int J Radiat Oncol Biol Phys. 2020 Apr 1;106(5):1063-1070. PubMed PMID: 31983558
• Y. Vinogradskiy, Q. Diot, B. Jones, R. Castillo, E. Castillo, J. Kwak, D. Bowles, I. Grills, N. Myziuk, T. Guerrero, C. Stevens, T. Schefter, L. E. Gaspar, B. Kavanagh, M. Miften, C. Rusthoven, “Evaluating Positron Emission Tomography-Based Functional Imaging Changes in the Heart After Chemo-Radiation for Patients With Lung Cancer,” Int. J. Radiat. Oncol. Biol. Phys. 106, 1063-1070 (2020)
• F. Forghani, A, Mahl, T, J. Patton, B. L. Jones, M. A. Borden, D. C. Westerly, C. Altunbas, M. Miften, D. H. Thomas, “Simulation of x-ray-induced acoustic imaging for absolute dosimetry: Accuracy of image reconstruction methods,” Med. Phys. 47, 1280-1290 (
• L. K. Schubert, K. Hendrickson, M. Miften, M. McNulty, Y. Vinogradskiy, D. H. Thomas, D. Westerly, K. Stuhr, J. Corral, D. Royer, “The Current State of Physics Plan Review Training in Medical Physics Residency Programs in North America,” Practical Radiation Oncology 10, e166-e172 (2020)
• D. H. Thomas, L. K. Schubert, Y. Vinogradskiy, S. Nath, B. Kavanagh, M. Miften, and B. Jones, “Technical Note: Deep Learning approach for automatic detection and identification of patient positioning devices for radiation therapy,” Med. Phys. 47, 5061-5069 (2020).
• D. H. Thomas, B. Miller, R. Rabinovitch, S. Milgrom, B. Kavanagh, Q. Diot, M. Miften, L. K. Schubert, “Integration of automation into an existing clinical workflow to improve efficiency and reduce errors in the manual treatment planning process for total body irradiation (TBI),” J. Appl. Clin. Med. Phys. 21:7:100-106 (2020).
• A. Mahl, B. Miller, M. Miften, and B. L. Jones, “Optimizing Coded Aperture Imaging techniques to allow for online tracking of fiducial markers with high-energy scattered radiation from treatment beam,” Med. Phys. 47, 4428-4438 (2020).
• Das SK, McGurk R, Miften M, Mutic S, Bowsher J, Bayouth J, Erdi Y, Mawlawi O, Boellaard R, Bowen SR, Xing L, Bradley J, Schoder H, Yin FF, Sullivan DC, Kinahan P. Task Group 174 Report: Utilization of [(18) F]Fluorodeoxyglucose Positron Emission Tomography ([(18) F]FDG-PET) in Radiation Therapy. Med Phys. 2019 Oct;46(10):e706-e725. PubMed PMID: 31230358
• Alexeev T, Kavanagh B, Miften M, Altunbas C. A novel total variation based ring artifact suppression method for CBCT imaging with two-dimensional antiscatter grids. Med Phys. 2019 May;46(5):2181-2193. PubMed PMID: 30802970
• Pinder-Arabpour A, Jones B, Castillo R, Castillo E, Guerrero T, Goodman K, Schefter T, Kwak J, Miften M, Vinogradskiy Y. Characterizing Spatial Lung Function for Esophageal Cancer Patients Undergoing Radiation Therapy. Int J Radiat Oncol Biol Phys. 2019 Mar 1;103(3):738-746. PubMed PMID: 30612962
• Ding Y, Campbell WG, Miften M, Vinogradskiy Y, Goodman KA, Schefter T, Jones BL. Quantifying Allowable Motion to Achieve Safe Dose Escalation in Pancreatic SBRT. Pract Radiat Oncol. 2019 Jul - Aug;9(4):e432-e442. PubMed PMID: 30951868
• Ding Y, Barrett HH, Kupinski MA, Vinogradskiy Y, Miften M, Jones BL. Objective assessment of the effects of tumor motion in radiation therapy. Med Phys. 2019 Jul;46(7):3311-3323. PubMed PMID: 31111961
• Vinogradskiy Y, Goodman KA, Schefter T, Miften M, Jones BL. The Clinical and Dosimetric Impact of Real-Time Target Tracking in Pancreatic SBRT. Int J Radiat Oncol Biol Phys. 2019 Jan 1;103(1):268-275. PubMed PMID: 30145394
• Behbahani RA, Diot Q, Kavanagh B, Serkova NJ, Miften M, Westerly DC. Electromagnetic wave propagation in a fast pulse line ion accelerator. Med Phys. 2019 Dec;46(12):5714-5721. PubMed PMID: 31622500
• Miften M, Mihailidis D, Kry SF, Reft C, Esquivel C, Farr J, Followill D, Hurkmans C, Liu A, Gayou O, Gossman M, Mahesh M, Popple R, Prisciandaro J, Wilkinson J. Management of radiotherapy patients with implanted cardiac pacemakers and defibrillators: A Report of the AAPM TG-203(†). Med Phys. 2019 Dec;46(12):e757-e788. PubMed PMID: 31571229
• Vinogradskiy Y, Faught A, Castillo R, Castillo E, Guerrero T, Miften M, Liu AK. Using 4DCT-ventilation to characterize lung function changes for pediatric patients getting thoracic radiotherapy. J Appl Clin Med Phys. 2018 Sep;19(5):407-412. PubMed PMID: 29943892
• Vinogradskiy Y, Rusthoven CG, Schubert L, Jones B, Faught A, Castillo R, Castillo E, Gaspar LE, Kwak J, Waxweiler T, Dougherty M, Gao D, Stevens C, Miften M, Kavanagh B, Guerrero T, Grills I. Interim Analysis of a Two-Institution, Prospective Clinical Trial of 4DCT-Ventilation-based Functional Avoidance Radiation Therapy. Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):1357-1365. PubMed PMID: 30353873
• Ding GX, Alaei P, Curran B, Flynn R, Gossman M, Mackie TR, Miften M, Morin R, Xu XG, Zhu TC. Image guidance doses delivered during radiotherapy: Quantification, management, and reduction: Report of the AAPM Therapy Physics Committee Task Group 180. Med Phys. 2018 May;45(5):e84-e99. PubMed PMID: 29468678
• Alexeev T, Kavanagh B, Miften M, Altunbas C. Two-dimensional antiscatter grid: A novel scatter rejection device for Cone-beam computed tomography. Med Phys. 2018 Feb;45(2):529-534. PubMed PMID: 29235120
• Faught AM, Olsen L, Schubert L, Rusthoven C, Castillo E, Castillo R, Zhang J, Guerrero T, Miften M, Vinogradskiy Y. Functional-guided radiotherapy using knowledge-based planning. Radiother Oncol. 2018 Dec;129(3):494-498. PubMed PMID: 29628292
• Miften M, Olch A, Mihailidis D, Moran J, Pawlicki T, Molineu A, Li H, Wijesooriya K, Shi J, Xia P, Papanikolaou N, Low DA. Tolerance limits and methodologies for IMRT measurement-based verification QA: Recommendations of AAPM Task Group No. 218. Med Phys. 2018 Apr;45(4):e53-e83. PubMed PMID: 29443390
• Faught AM, Yamamoto T, Castillo R, Castillo E, Zhang J, Miften M, Vinogradskiy Y. Evaluating Which Dose-Function Metrics Are Most Critical for Functional-Guided Radiation Therapy. Int J Radiat Oncol Biol Phys. 2017 Sep 1;99(1):202-209. PubMed PMID: 28816147
• Waxweiler T, Schubert L, Diot Q, Faught A, Stuhr K, Castillo R, Castillo E, Guerrero T, Rusthoven C, Gaspar L, Kavanagh B, Miften M, Vinogradskiy Y. A complete 4DCT-ventilation functional avoidance virtual trial: Developing strategies for prospective clinical trials. J Appl Clin Med Phys. 2017 May;18(3):144-152. PubMed PMID: 28436107
• Campbell WG, Jones BL, Schefter T, Goodman KA, Miften M. An evaluation of motion mitigation techniques for pancreatic SBRT. Radiother Oncol. 2017 Jul;124(1):168-173. PubMed PMID: 28571887
• Vinogradskiy Y, Jackson M, Schubert L, Jones B, Castillo R, Castillo E, Guerrero T, Mitchell J, Rusthoven C, Miften M, Kavanagh B. Assessing the use of 4DCT-ventilation in pre-operative surgical lung cancer evaluation. Med Phys. 2017 Jan;44(1):200-208. PubMed PMID: 28102961
• Campbell WG, Miften M, Jones BL. Automated target tracking in kilovoltage images using dynamic templates of fiducial marker clusters. Med Phys. 2017 Feb;44(2):364-374. PubMed PMID: 28035655
• Liu F, Tai A, Lee P, Biswas T, Ding GX, El Naqa I, Grimm J, Jackson A, Kong FS, LaCouture T, Loo B Jr, Miften M, Solberg T, Li XA. Tumor control probability modeling for stereotactic body radiation therapy of early-stage lung cancer using multiple bio-physical models. Radiother Oncol. 2017 Feb;122(2):286-294. PubMed PMID: 27871671
• Campbell WG, Miften M, Olsen L, Stumpf P, Schefter T, Goodman KA, Jones BL. Neural network dose models for knowledge-based planning in pancreatic SBRT. Med Phys. 2017 Dec;44(12):6148-6158. PubMed PMID: 28994459
• Altunbas C, Kavanagh B, Alexeev T, Miften M. Transmission characteristics of a two dimensional antiscatter grid prototype for CBCT. Med Phys. 2017 Aug;44(8):3952-3964. PubMed PMID: 28513847
• Vinogradskiy Y, Schubert L, Diot Q, Waxweiller T, Koo P, Castillo R, Castillo E, Guerrero T, Rusthoven C, Gaspar L, Kavanagh B, Miften M. Regional Lung Function Profiles of Stage I and III Lung Cancer Patients: An Evaluation for Functional Avoidance Radiation Therapy. Int J Radiat Oncol Biol Phys. 2016 Jul 15;95(4):1273-80. PubMed PMID: 27354134
• Zhao J, Yorke ED, Li L, Kavanagh BD, Li XA, Das S, Miften M, Rimner A, Campbell J, Xue J, Jackson A, Grimm J, Milano MT, Spring Kong FM. Simple Factors Associated With Radiation-Induced Lung Toxicity After Stereotactic Body Radiation Therapy of the Thorax: A Pooled Analysis of 88 Studies. Int J Radiat Oncol Biol Phys. 2016 Aug 1;95(5):1357-1366. PubMed PMID: 27325482
• Diot Q, Kavanagh B, Vinogradskiy Y, Garg K, Gaspar L, Miften M. Lung deformations and radiation-induced regional lung collapse in patients treated with stereotactic body radiation therapy. Med Phys. 2015 Nov;42(11):6477-87. PubMed PMID: 26520737
• Jones BL, Schefter T, Miften M. Adaptive motion mapping in pancreatic SBRT patients using Fourier transforms. Radiother Oncol. 2015 May;115(2):217-22. PubMed PMID: 25890573
• Brennan D, Schubert L, Diot Q, Castillo R, Castillo E, Guerrero T, Martel MK, Linderman D, Gaspar LE, Miften M, Kavanagh BD, Vinogradskiy Y. Clinical validation of 4-dimensional computed tomography ventilation with pulmonary function test data. Int J Radiat Oncol Biol Phys. 2015 Jun 1;92(2):423-9. PubMed PMID: 25817531
• Jones BL, Westerly D, Miften M. Calculating tumor trajectory and dose-of-the-day using cone-beam CT projections. Med Phys. 2015 Feb;42(2):694-702. PubMed PMID: 25652483
• Altunbas C, Hankinson TC, Miften M, Tello T, Plimpton SR, Stuhr K, Liu AK. Rotational setup errors in pediatric stereotactic radiation therapy. Pract Radiat Oncol. 2013 Jul-Sep;3(3):194-8. PubMed PMID: 24674364
• Jones BL, Gan G, Kavanagh B, Miften M. Effect of endorectal balloon positioning errors on target deformation and dosimetric quality during prostate SBRT. Phys Med Biol. 2013 Nov 21;58(22):7995-8006. PubMed PMID: 24169860
• Altunbas C, Kavanagh B, Dzingle W, Stuhr K, Gaspar L, Miften M. Dosimetric errors during treatment of centrally located lung tumors with stereotactic body radiation therapy: Monte Carlo evaluation of tissue inhomogeneity corrections. Med Dosim. 2013 Winter;38(4):436-41. PubMed PMID: 24119416
• Vinogradskiy Y, Diot Q, Kavanagh B, Schefter T, Gaspar L, Miften M. Spatial and dose-response analysis of fibrotic lung changes after stereotactic body radiation therapy. Med Phys. 2013 Aug;40(8):081712. PubMed PMID: 23927309
• Fields EC, Rabinovitch R, Ryan NE, Miften M, Westerly DC. A detailed evaluation of TomoDirect 3DCRT planning for whole-breast radiation therapy. Med Dosim. 2013 Winter;38(4):401-6. PubMed PMID: 23809692
• Amin NP, Miften M, Thornton D, Ryan N, Kavanagh B, Gaspar LE. Effect of induction chemotherapy on estimated risk of radiation pneumonitis in bulky non-small cell lung cancer. Med Dosim. 2013 Autumn;38(3):320-6. PubMed PMID: 23611631
• Glide-Hurst C, Bellon M, Foster R, Altunbas C, Speiser M, Altman M, Westerly D, Wen N, Zhao B, Miften M, Chetty IJ, Solberg T. Commissioning of the Varian TrueBeam linear accelerator: a multi-institutional study. Med Phys. 2013 Mar;40(3):031719. PubMed PMID: 23464314