Chris Nyquist, MD, MSPH
Professor, Pediatrics-Infectious Diseases

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Medical School:
  • MD, University of Michigan Medical School (1987)
Graduate School :
  • MSPH, University of Colorado Denver (1997)
Undergraduate School:
  • BS, University of Michigan (MI) (1985)
Internship:
  • UCLA Medical Center Program (1988)
Residency:
  • UCLA Medical Center Program, Chief Resident, Pediatrics (1991)
Fellowships:
  • University of Colorado, Pediatric Infectious Diseases (1995)
Languages: English, Finnish
Department: Pediatrics-Infectious Diseases

Professional Titles

  • Chief Safety and Epidemiology Officer

Recognition & Awards

  • Top Doctor-Pediatric Infectious Diseases, 5280 Magazine (2017)
  • Top Doctor-Pediatric Infectious Diseases, Colorado Parent Magazine (2017)
  • Nominee: Award for the Best Manuscript in 2016 in the Category of Assessment, Center for Disease Control and Prevention (2016)
    Severe Respiratory Illness associated with a Nationwide Outbreak of Enterovirus D68 in the US (2014): a Descriptive Epidemiological Investigation. Lancet Respir Med 2015;3(11):879-87.
  • Nominee Empirical Outcomes, The Unit Acquired Infections Committee Pediatric Intensive Care Unit., The Sixth Annual Nursing Excellence Awards, Children’s Hospital Colorado (2016)
  • Award for Outstanding Research Article in Biosurveillance: Impact on Field of Biosurveillance, International Society for Disease Surveillance (2015)

Research Interests

Dr. Nyquist's scientific interests include immunizations, hospital epidemiology/infection control, patient safety, occupational health and health equity . She is involved in a wide range of teaching activities. In addition, Dr. Nyquist participates in many local, regional, and national committees related to Pediatric Infectious Diseases and Healthcare Epidemiology.

Publications

  • Los J, Gaydos CA, Gibert CL, Gorse GJ, Lykken J, Nyquist AC, Price CS, Radonovich LJ Jr, Rattigan S, Reich N, Rodriguez-Barradas M, Simberkoff M, Bessesen M, Brown A, Cummings DAT, Perl TM. Take-home kits to detect respiratory viruses among healthcare personnel: Lessons learned from a cluster randomized clinical trial. Am J Infect Control. 2021 Jul;49(7):893-899. PubMed PMID: 33581146
  • Bessesen MT, Rattigan S, Frederick J, Cummings DAT, Gaydos CA, Gibert CL, Gorse GJ, Nyquist AC, Price CS, Reich NG, Simberkoff MS, Brown AC, Radonovich LJ Jr, Perl TM, Rodriguez-Barradas MC. Outpatient healthcare personnel knowledge and attitudes towards infection prevention measures for protection from respiratory infections. Am J Infect Control. 2021 Nov;49(11):1369-1375. PubMed PMID: 34182066
  • Simberkoff MS, Rattigan SM, Gaydos CA, Gibert CL, Gorse GJ, Nyquist AC, Price CS, Reich N, Rodriguez-Barradas MC, Bessesen M, Brown A, Cummings DAT, Radonovich LJ, Perl TM. Impact of mandatory vaccination of healthcare personnel on rates of influenza and other viral respiratory pathogens. Infect Control Hosp Epidemiol. 2021 Aug 5;:1-5. [Epub ahead of print] PubMed PMID: 34350820
  • Gorse GJ, Rattigan SM, Kirpich A, Simberkoff MS, Bessesen MT, Gibert C, Nyquist AC, Price CS, Gaydos CA, Radonovich LJ, Perl TM, Rodriguez-Barradas MC, Cummings DAT. Influence of Pre-Season Antibodies against Influenza Virus on Risk of Influenza Infection among Health Care Personnel. J Infect Dis. 2021 Sep 17. [Epub ahead of print] PubMed PMID: 34534319
  • Gerber JS, Jackson MA, Tamma PD, Zaoutis TE. Antibiotic Stewardship in Pediatrics. Pediatrics. 2021 Jan;147(1). PubMed PMID: 33372120
  • Coffin SE, Abanyie F, Bryant K, Cantey J, Fiore A, Fritz S, Guzman-Cottrill J, Hersh AL, Huskins WC, Kociolek LK, Kronman M, Lautenbach E, Lee G, Linam M, Logan LK, Milstone A, Newland J, Nyquist AC, Palazzi DL, Patel S, Puopolo K, Reddy SC, Saiman L, Sandora T, Shane AL, Smith M, Tamma PD, Zaoutis T, Zerr D, Gerber JS. Pediatric research priorities in healthcare-associated infections and antimicrobial stewardship. Infect Control Hosp Epidemiol. 2021 May;42(5):519-522. PubMed PMID: 33239122
  • Cummings DAT, Radonovich LJ, Gorse GJ, Gaydos CA, Bessesen MT, Brown AC, Gibert CL, Hitchings MDT, Lessler J, Nyquist AC, Rattigan SM, Rodriguez-Barradas MC, Price CS, Reich NG, Simberkoff MS, Perl TM. Risk Factors for Healthcare Personnel Infection With Endemic Coronaviruses (HKU1, OC43, NL63, 229E): Results from the Respiratory Protection Effectiveness Clinical Trial (ResPECT). Clin Infect Dis. 2021 Dec 6;73(11):e4428-e4432. PubMed PMID: 32645144
  • Brown AC, Lauer SA, Robinson CC, Nyquist AC, Rao S, Reich NG. Evaluating the ALERT algorithm for local outbreak onset detection in seasonal infectious disease surveillance data. Stat Med. 2020 Apr 15;39(8):1145-1155. PubMed PMID: 31985869
  • Chung S, Baum CR, Nyquist AC. Chemical-Biological Terrorism and Its Impact on Children. Pediatrics. 2020 Feb;145(2). PubMed PMID: 31988168
  • Cummings DAT, Radonovich LJ, Gorse GJ, Gaydos CA, Bessesen MT, Brown AC, Gibert CL, Hitchings MDT, Lessler J, Nyquist AC, Rattigan SM, Rodriguez-Barradas MC, Price CS, Reich NG, Simberkoff MS, Perl TM. Risk Factors for Healthcare Personnel Infection with Endemic Coronaviruses (HKU1, OC43, NL63, 229E): Results from the Respiratory Protection Effectiveness Clinical Trial (ResPECT). Clin Infect Dis. 2020 Jul 9. [Epub ahead of print] PubMed PMID: 32645144
  • . Recommended Childhood and Adolescent Immunization Schedule: United States, 2020. Pediatrics. 2020 Mar;145(3). PubMed PMID: 32019815
  • . Recommendations for Prevention and Control of Influenza in Children, 2020-2021. Pediatrics. 2020 Oct;146(4). PubMed PMID: 32900875
  • Coffin SE, Abanyie F, Bryant K, Cantey J, Fiore A, Fritz S, Guzman-Cottrill J, Hersh AL, Huskins WC, Kociolek LK, Kronman M, Lautenbach E, Lee G, Linam M, Logan LK, Milstone A, Newland J, Nyquist AC, Palazzi DL, Patel S, Puopolo K, Reddy SC, Saiman L, Sandora T, Shane AL, Smith M, Tamma PD, Zaoutis T, Zerr D, Gerber JS. Pediatric research priorities in healthcare-associated infections and antimicrobial stewardship. Infect Control Hosp Epidemiol. 2020 Nov 26;:1-4. [Epub ahead of print] PubMed PMID: 33239122
  • Chung S, Baum CR, Nyquist AC. Chemical-Biological Terrorism and Its Impact on Children. Pediatrics. 2020 Feb;145(2). PubMed PMID: 31988169
  • West K, Janelle S, Schutz K, Hamilton S, Mayo K, Cichon MK, Nyquist AC, Bamberg WM, Dominguez SR. Outbreak of Serratia marcescens bacteremia in pediatric patients epidemiologically linked to pre-filled heparin flushes. Infect Control Hosp Epidemiol. 2019 Oct;40(10):1201-1202. PubMed PMID: 31340879
  • Radonovich LJ Jr, Simberkoff MS, Bessesen MT, Brown AC, Cummings DAT, Gaydos CA, Los JG, Krosche AE, Gibert CL, Gorse GJ, Nyquist AC, Reich NG, Rodriguez-Barradas MC, Price CS, Perl TM. N95 Respirators vs Medical Masks for Preventing Influenza Among Health Care Personnel: A Randomized Clinical Trial. JAMA. 2019 Sep 3;322(9):824-833. PubMed PMID: 31479137
  • . Recommended Childhood and Adolescent Immunization Schedules: United States, 2019. Pediatrics. 2019 Mar;143(3). PubMed PMID: 30824606
  • Puopolo KM, Lynfield R, Cummings JJ. Management of Infants at Risk for Group B Streptococcal Disease. Pediatrics. 2019 Aug;144(2). PubMed PMID: 31285392
  • . Recommendations for Prevention and Control of Influenza in Children, 2019-2020. Pediatrics. 2019 Oct;144(4). PubMed PMID: 31477606
  • Frederick J, Brown AC, Cummings DA, Gaydos CA, Gibert CL, Gorse GJ, Los JG, Nyquist AC, Perl TM, Price CS, Radonovich LJ, Reich NG, Rodriguez-Barradas MC, Bessesen MT, Simberkoff MS. Protecting Healthcare Personnel in Outpatient Settings: The Influence of Mandatory Versus Nonmandatory Influenza Vaccination Policies on Workplace Absenteeism During Multiple Respiratory Virus Seasons. Infect Control Hosp Epidemiol. 2018 Apr;39(4):452-461. PubMed PMID: 29514719
  • . Recommendations for Prevention and Control of Influenza in Children, 2018-2019. Pediatrics. 2018 Oct;142(4). PubMed PMID: 30177511
  • . Recommended Childhood and Adolescent Immunization Schedule-United States, 2017. Pediatrics. 2017 Mar;139(3). PubMed PMID: 28167516
  • Maldonado YA, Read JS. Diagnosis, Treatment, and Prevention of Congenital Toxoplasmosis in the United States. Pediatrics. 2017 Feb;139(2). PubMed PMID: 28138010
  • Bernstein HH, Bocchini JA Jr. The Need to Optimize Adolescent Immunization. Pediatrics. 2017 Mar;139(3). PubMed PMID: 28167517
  • Bernstein HH, Bocchini JA Jr. Practical Approaches to Optimize Adolescent Immunization. Pediatrics. 2017 Mar;139(3). PubMed PMID: 28167515
  • . Elimination of Perinatal Hepatitis B: Providing the First Vaccine Dose Within 24 Hours of Birth. Pediatrics. 2017 Sep;140(3). PubMed PMID: 28847980
  • Davies HD, Jackson MA, Rice SG. Infectious Diseases Associated With Organized Sports and Outbreak Control. Pediatrics. 2017 Oct;140(4). PubMed PMID: 28947608
  • . Recommendations for Prevention and Control of Influenza in Children, 2017 - 2018. Pediatrics. 2017 Oct;140(4). PubMed PMID: 28870977
  • Rathore MH, Jackson MA. Infection Prevention and Control in Pediatric Ambulatory Settings. Pediatrics. 2017 Nov;140(5). PubMed PMID: 29061869
  • Radonovich LJ Jr, Bessesen MT, Cummings DA, Eagan A, Gaydos C, Gibert C, Gorse GJ, Nyquist AC, Reich NG, Rodrigues-Barradas M, Savor-Price C, Shaffer RE, Simberkoff MS, Perl TM. The Respiratory Protection Effectiveness Clinical Trial (ResPECT): a cluster-randomized comparison of respirator and medical mask effectiveness against respiratory infections in healthcare personnel. BMC Infect Dis. 2016 Jun 2;16:243. PubMed PMID: 27255755
  • Harris AD, Pineles L, Anderson D, Woeltje KF, Trick WE, Kaye KS, Yokoe DS, Nyquist AC, Calfee DP, Leekha S. Which Comorbid Conditions Should We Be Analyzing as Risk Factors for Healthcare-Associated Infections?. Infect Control Hosp Epidemiol. 2016 Dec 29;:1-6. [Epub ahead of print] PubMed PMID: 28031061
  • Jackson MA, Schutze GE. The Use of Systemic and Topical Fluoroquinolones. Pediatrics. 2016 Nov;138(5). PubMed PMID: 27940800
  • Nyquist AC. Unexplained Fever. It's Hot. J Pediatric Infect Dis Soc. 2016 Sep;5(3):257-8. PubMed PMID: 26407278
  • . Recommendations for Prevention and Control of Influenza in Children, 2016-2017. Pediatrics. 2016 Oct;138(4). PubMed PMID: 27600320
  • Edwards KM, Hackell JM. Countering Vaccine Hesitancy. Pediatrics. 2016 Sep;138(3). PubMed PMID: 27573088
  • . Medical Versus Nonmedical Immunization Exemptions for Child Care and School Attendance. Pediatrics. 2016 Sep;138(3). PubMed PMID: 27573087
  • . Recommendations for Serogroup B Meningococcal Vaccine for Persons 10 Years and Older. Pediatrics. 2016 Sep;138(3). PubMed PMID: 27573083
  • Davies HD, Byington CL. Parental Presence During Treatment of Ebola or Other Highly Consequential Infection. Pediatrics. 2016 Sep;138(3). PubMed PMID: 27550981
  • Davies HD. Infectious Complications With the Use of Biologic Response Modifiers in Infants and Children. Pediatrics. 2016 Aug;138(2). PubMed PMID: 27432853
  • Reich NG, Cummings DA, Lauer SA, Zorn M, Robinson C, Nyquist AC, Price CS, Simberkoff M, Radonovich LJ, Perl TM. Triggering Interventions for Influenza: The ALERT Algorithm. Clin Infect Dis. 2015 Feb 15;60(4):499-504. PubMed PMID: 25414260
  • Midgley CM, Watson JT, Nix WA, Curns AT, Rogers SL, Brown BA, Conover C, Dominguez SR, Feikin DR, Gray S, Hassan F, Hoferka S, Jackson MA, Johnson D, Leshem E, Miller L, Nichols JB, Nyquist AC, Obringer E, Patel A, Patel M, Rha B, Schneider E, Schuster JE, Selvarangan R, Seward JF, Turabelidze G, Oberste MS, Pallansch MA, Gerber SI. Severe respiratory illness associated with a nationwide outbreak of enterovirus D68 in the USA (2014): a descriptive epidemiological investigation. Lancet Respir Med. 2015 Nov;3(11):879-87. PubMed PMID: 26482320
  • Nyquist AC. Unexplained Fever. It's Hot. J Pediatric Infect Dis Soc. 2015 Aug 16. [Epub ahead of print] PubMed PMID: 26407278
  • Reich NG, Cummings DA, Lauer SA, Zorn M, Robinson C, Nyquist AC, Price CS, Simberkoff M, Radonovich LJ, Perl TM. Triggering interventions for influenza: the ALERT algorithm. Clin Infect Dis. 2015 Feb 15;60(4):499-504. PubMed PMID: 25414260
  • Anderson DJ, Podgorny K, Berríos-Torres SI, Bratzler DW, Dellinger EP, Greene L, Nyquist AC, Saiman L, Yokoe DS, Maragakis LL, Kaye KS. Strategies to prevent surgical site infections in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol. 2014 Sep;35 Suppl 2:S66-88. PubMed PMID: 25376070
  • Rao S, Nyquist AC. Respiratory viruses and their impact in healthcare. Curr Opin Infect Dis. 2014 Aug;27(4):342-7. PubMed PMID: 24977685
  • Anderson DJ, Podgorny K, Berríos-Torres SI, Bratzler DW, Dellinger EP, Greene L, Nyquist AC, Saiman L, Yokoe DS, Maragakis LL, Kaye KS. Strategies to prevent surgical site infections in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol. 2014 Jun;35(6):605-27. PubMed PMID: 24799638
  • Smit MA, Nyquist AC, Todd JK. Infectious shock and toxic shock syndrome diagnoses in hospitals, Colorado, USA. Emerg Infect Dis. 2013 Nov;19(11):1855-8. PubMed PMID: 24188357
  • Vitale MG, Riedel MD, Glotzbecker MP, Matsumoto H, Roye DP, Akbarnia BA, Anderson RC, Brockmeyer DL, Emans JB, Erickson M, Flynn JM, Lenke LG, Lewis SJ, Luhmann SJ, McLeod LM, Newton PO, Nyquist AC, Richards BS 3rd, Shah SA, Skaggs DL, Smith JT, Sponseller PD, Sucato DJ, Zeller RD, Saiman L. Building consensus: development of a Best Practice Guideline (BPG) for surgical site infection (SSI) prevention in high-risk pediatric spine surgery. J Pediatr Orthop. 2013 Jul-Aug;33(5):471-8. PubMed PMID: 23752142
  • Guzman-Cottrill JA, Phillipi CA, Dolan SA, Nyquist AC, Win A, Siegel J. Free vaccine programs to cocoon high-risk infants and children against influenza and pertussis. Am J Infect Control. 2012 Nov;40(9):872-6. PubMed PMID: 23116758
  • Dolan SA, Littlehorn C, Glodé MP, Dowell E, Xavier K, Nyquist AC, Todd JK. Association of Bacillus cereus infection with contaminated alcohol prep pads. Infect Control Hosp Epidemiol. 2012 Jul;33(7):666-71. PubMed PMID: 22669227
  • Ballard MR, Miller NH, Nyquist AC, Elise B, Baulesh DM, Erickson MA. A multidisciplinary approach improves infection rates in pediatric spine surgery. J Pediatr Orthop. 2012 Apr-May;32(3):266-70. PubMed PMID: 22411332
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Professional Memberships

  • SHEA, Member
  • IDSA, Member
  • Pediatric Infectious Diseases Society, Fellow
  • American Academy of Pediatrics (AAP), Fellow

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado
  • University of Colorado Hospital

Specialty Information

Specialties
  • Pediatric Infectious Diseases, Board Certification (1997)
  • Pediatrics, Board Certification (1990)
Conditions & Treatments
  • Infections
  • Infections - Viral Infections
  • Infections - Sexually Transmitted Diseases
  • Infections - Pneumonia
  • Infections - Influenza
  • Infections - Fungal Infections
  • Infections - Bacterial Infections
  • Child and Teen Health
  • Immune System
Clinical Interests
I am interested in Hospital Epidemiology, Safety and Health Equity.

Public Speaking
Yes

General Information

Medical Schools:
  • MD, University of Michigan Medical School (1987)
Graduate Schools:
  • MSPH, University of Colorado Denver (1997)
Undergraduate Schools:
  • BS, University of Michigan (MI) (1985)
Internships:
  • UCLA Medical Center Program (1988)
Residency Programs:
  • UCLA Medical Center Program, Chief Resident, Pediatrics (1991)
Fellowships:
  • University of Colorado, Pediatric Infectious Diseases (1995)
Languages: English, Finnish
Department: Pediatrics-Infectious Diseases
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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