Joseph Gal, PhD, MS

Professor Emeritus, Medicine-Clinical Pharmacology/Toxicology


Publications

  • Gal, J., Chiral Drugs from a Historical Point of View, in Chirality in Drug Research and Development, E. Francotte and W. Lindner, editors, Wiley-VCH, in press, publication scheduled for June 2006.
  • Gal, J., Carl Friedrich Naumann and the introduction of enantio terminology: a review and analysis on the 150th anniversary. Chirality, in press, 2006.
  • Peeters, O.M., Polavarapu, P.L., Zhang, P., Gera, L., and Gal, J., (+)-1-[(R)-3,3,3-Trifluoro-2-methoxy-2-phenylpropionyl]-4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine methanol solvate, Acta Cryst.., E62: o191-o192 (2005)
  • Gal, J., Chiral Drugs from a Historical Point of View, in Chirality in Drug Research, E. Francotte and W. Lindner, editors, Wiley-VCH, 2006.
  • Gal, J., Carl Friedrich Naumann and the introduction of enantio terminology: a review and analysis on the 150th anniversary. Chirality, 19(2) 89-98 2007.
  • Gal, J., "From fever tree in Peru to chiral selector in chromatography: The 375-year history of the antimalarial drug quinine", 18th International Symposium on Chiral Discrimination (ISCD 18, Chirality 2006), Busan, South Korea, June 28, 2006, ISCD 18 Abstract Book, L-24, p.68
  • Gal,J "The discovery of biological enantioselectivity: Louis Pasteur and the fermentation of tartaric acid, 1857 - A review and analysis 150 years later", Chirality, 20:5-19 (2008).
  • Gal, J, "When did Louis Pasteur present his memoir on the discovery of molecular chirality to the Academie des Sciences? Analysis of a discrepancy", Chirality, in press, 2008.
  • J. Gal, Pedro Cintas, Early History of the Recognition of Molecular Biochirality. In Biochirality: Origins, Evolution, and Molecular Recognition, P. Cintas, editor. Top Curr Chem (2013) 333: 1–40. DOI: 10.1007/128_2012_406, Springer-Verlag, Berlin, Heidelberg
  • J. Gal, Molecular Chirality: Language, History, and Significance. In: Enantiomers Separation, V. Schurig, editor. Top Curr Chem (2013) DOI: 10.1007/128_2013_435 # Springer-Verlag Berlin Heidelberg
  • Gal, J. Molecular chirality in chemistry and biology: Historical milestones. Helv. Chim. Acta, 96:1617-1657, 2013.
  • Gal, J. Citation for Chemical Breakthrough Awards: choosing Pasteur’s award-winning publication. Bull. Hist. Chem., 38:7-12, 2013.
  • Gal, J and Seeman, J. I. In defense of the use of the French language in scientific communication, 1965-1985. A serious national deliberation and an ingeniously clever takeoff on the theme by R. B. Woodward. Bull. Hist. Chem., in press, 2013.
  • Gal, J, Welch, C, "Bloopers in Chirality: Use and Abuse Of Stereochemical Language", 19th International Symposium on Chiral Discrimination (ISCD 19), San Diego, CA, July 2007, ISCD 19 Program Abstracts.
  • Gal, J. Molecular chirality in chemistry and biology: Historical milestones. In: Organic Stereochemistry – Guiding Principles and Biomedical Relevance, B. Testa, M. V. Kisakurek, and J. Caldwell, editors, Helvetica Chimica Acta Publishers, VHCA, in press, 2013
  • Gal, J., When did Louis Pasteur present his memoir to the Académie des Science? Analysis of a discrepancy. Chirality, 20:1072-1084 (2008).
  • Eakins, S., Kholodovych, V., Ai, N., Sinz, M., Gal, J., Gera, L., Welsh, W.J., Bachmann, K., and Mani, S., Computational discovery of novel low micromolecular human pregnane X receptor antagonists. Mol. Pharmacol., 74:662-672 (2008).
  • Gal, J. "Louis Pasteur, Language, and Molecular Chirality - I. Background and Dissymmetry". Chirality, 2010, in press.
  • Gal, J. "Louis Pasteur, language, and molecular chirality–I. Background and dissymmetry". Chirality, 23:1-16 (2011)
  • Gal, J. Molecular chirality in chemistry and biology: Historical milestones. In Organic Stereochemistry – Guiding Principles and Biomedical Relevance, B. Testa, M. V. Kisakurek, and J. Caldwell, editors, Helvetica Chimica Acta Publishers, Wiley-VHCA, Zurich, 2014, pp 317-365.
  • Gal, J. Molecular chirality in chemistry and biology: Historical milestones. In Organic Stereochemistry – Guiding Principles and Biomedical Relevance, B. Testa, M. V. Kisakurek, and J. Caldwell, editors, Helvetica Chimica Acta Publishers, Wiley-VHCA, Zurich, 2014, pp 317-365.
  • Gal, J and Seeman, J. I. In defense of the use of the French language in scientific communication, 1965-1985. National and international deliberations and an ingeniously clever takeoff on the theme by R. B. Woodward. Bull. Hist. Chem., 39:73-94 (2014).
  • Gal, J. Remembering Fritz Haber in the Year 2015. L'Actualité Chimique, in press.
  • Pyrgaki, C., Steve J. Bannister, S., Gera, L., Gerber, J.G., and Gal, J., Stereoselective determination of the epimer mixtures of itraconazole in human blood plasma using HPLC and fluorescence detection. Chirality, in press, 2011
  • Gal, J. Stereochemical vocabulary for structures that are chiral but not asymmetric: History, analysis, and proposal for a rational terminology. Chirality, in press, 2011
  • Gal, J. Louis Pasteur, stereochemist. Kémiai Panoráma, in press, 2011
  • "Molecular Chirality in Murder-Mystery Novels and In Real-Life Forensic Toxicology", 22nd International Symposium On Chiral Discrimination, Sapporo, Japan, July 15, 2010 (invited).
  • Did John Frederick William Herschel discover molecular chirality before Louis Pasteur? ACS Fall Meeting, Boston, MS, August 22, 2010
  • Teaching stereochemistry: Proposal for a terminology of chiral but not asymmetric chemical structures that would eliminate the existing confusion. ACS Fall Meeing, Boston, MS, August 26, 2010
  • Pyrgaki, C., Steve J. Bannister, S., Gera, L., Gerber, J.G., and Gal, J., Stereoselective determination of the epimer mixtures of itraconazole in human blood plasma using HPLC and fluorescence detection. Chirality, 23: 495-503, 2011
  • Gal, J. Louis Pasteur, a sztereokémikus. Kémiai Panoráma, 2011(2), 4-8.
  • Gal, J. Stereochemical vocabulary for structures that are chiral but not asymmetric: History, analysis, and proposal for a rational terminology. Chirality, 23:647-659, 2011.
  • Gal, J. A sztereoszelektivitás felfedezése biológiai receptorokon – Arnaldo Piutti és az aszparagin enantiomerek íze. Kémiai Panoráma, 2012, in press.
  • Gal, J. The discovery of stereoselectivity at biological receptors: Arnaldo Piutti, the asparagine enantiomers, and sweet taste – a review and analysis on the 125th anniversary. Chirality, in press, 2012.
  • Gal, J, Cintas, P. The early history of the recognition of biological chiroselectivity. In Biochirality: Origins, Evolution and Molecular Recognition, Pedro Cintas, editor. Springer, 2012, invited chapter, in preparation.
  • Gal, J. The discovery of stereoselectivity at biological receptors: Arnaldo Piutti, the asparagine enantiomers, and sweet taste – a review and analysis on the 125th anniversary. Chirality, 24:959-976 (2012).
  • Gal, J, Cintas, P. Early history of the recognition of molecular biochirality. In Biochirality: Origins, Evolution, and Molecular Recognition, Pedro Cintas, editor. Springer, 2013, in press.
  • Gal, J, Molecular chirality: language, history, and significance. In Enantiomers Separation, Volker Schurig, editor, Springer, 2013, in press
  • Gal, J, Citation for Chemical Breakthrough Awards: choosing Pasteur’s award-winning publication. Bull. Hist. Chem., in press, 2013

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000