Professor and Chair
(2000)
School of Medicine,
Anesthesiology
Publications
Dahan A, Olofsen E, Henthorn TK, van Velzen M, Niesters M. Ketamine Pharmacodynamics Entangled: Reply. Anesthesiology. 2022 Sep 9. [Epub ahead of print] PubMed PMID: 36095056
Dahan A, Henthorn TK. Editorial: Ketamine for treatment of acute and chronic pain: The relationship of mechanism and exposure to therapeutic outcome. Front Pain Res (Lausanne). 2022;3:991569. PubMed PMID: 36081983
Sempio C, Huestis MA, Kaplan B, Klawitter J, Christians U, Henthorn TK. Urinary clearance of 11-nor-9-carboxy-?(9) -tetrahydrocannabinol: A detailed pharmacokinetic analysis. Drug Test Anal. 2022 Aug;14(8):1368-1376. PubMed PMID: 35332698
Olofsen E, Kamp J, Henthorn TK, van Velzen M, Niesters M, Sarton E, Dahan A. Ketamine Psychedelic and Antinociceptive Effects Are Connected. Anesthesiology. 2022 May 1;136(5):792-801. PubMed PMID: 35188952
Henthorn TK, Krejcie TC, Avram MJ. Elimination Clearance of Dexmedetomidine: Cross-examining What the Data Say. Anesthesiology. 2022 Feb 1;136(2):258-260. PubMed PMID: 34965290
Editorial: Ketamine for treatment of acute and chronic pain: The relationship of mechanism and exposure to therapeutic outcome. Front Pain Res (Lausanne). 2022 Aug 23;3:991569.
doi: 0.3389/fpain.2022.991569
Meissner K, Henthorn TK. How relevant is stereoselectivity to the side-effects of ketamine?. Br J Anaesth. 2021 Jul;127(1):1-2. PubMed PMID: 33965204
Sempio C, Bidwell LC, Hutchison K, Huestis MA, Klawitter J, Christians U, Henthorn TK. Using Population Pharmacokinetic Modeling to Estimate Exposure to ?9-Tetrahydrocannabinol in an Observational Study of Cannabis Smokers in Colorado. Ther Drug Monit. 2021 Aug 1;43(4):536-545. PubMed PMID: 33656464
Sempio C, Wymore E, Palmer C, Bunik M, Henthorn TK, Christians U, Klawitter J. Detection of Cannabinoids by LC-MS-MS and ELISA in Breast Milk. J Anal Toxicol. 2021 Aug 14;45(7):686-692. PubMed PMID: 33002141
Sempio C, Huestis MA, Mikulich-Gilbertson SK, Klawitter J, Christians U, Henthorn TK. Population pharmacokinetic modeling of plasma ?9-tetrahydrocannabinol and an active and inactive metabolite following controlled smoked cannabis administration. Br J Clin Pharmacol. 2020 Mar;86(3):611-619. PubMed PMID: 31747464
Christians U, Henthorn TK, Walson PD, Oellerich M, Eliasson E. In Memoriam: Professor Folke Sjöqvist. Ther Drug Monit. 2020 Apr 15. [Epub ahead of print] PubMed PMID: 32304489
Kamp J, Olofsen E, Henthorn TK, van Velzen M, Niesters M, Dahan A. Ketamine Pharmacokinetics. Anesthesiology. 2020 Sep 30. [Epub ahead of print] PubMed PMID: 32997732
Sempio C, Wymore E, Palmer C, Bunik M, Henthorn TK, Christians U, Klawitter J. Detection of Cannabinoids by LC-MS-MS and ELISA in Breast Milk. J Anal Toxicol. 2020 Oct 2. [Epub ahead of print] PubMed PMID: 33002141
Kamp J, Olofsen E, Henthorn TK, van Velzen M, Niesters M, Dahan A. Ketamine Pharmacokinetics. Anesthesiology. 2020 Dec 1;133(6):1192-1213. PubMed PMID: 32997732
Christians U, Henthorn TK, Walson PD, Oellerich M, Eliasson E. In Memoriam: Professor Folke Sjöqvist. Ther Drug Monit. 2020 Jun;42(3):353. PubMed PMID: 32304489
Sempio C, Huestis MA, Mikulich-Gilbertson SK, Klawitter J, Christians U, Henthorn TK. Population pharmacokinetic modeling of plasma ?9-tetrahydrocannabinol and an active and inactive metabolite following controlled smoked cannabis administration. Br J Clin Pharmacol. 2020 Mar;86(3):611-619. PubMed PMID: 31747464
Brooks Peterson M, Cohen MN, O'Neill BR, Garg S, Child J, Henthorn TK, Galinkin JG. Preoperative Vancomycin Administration for Surgical Site Prophylaxis: Plasma and Soft-Tissue Concentrations in Pediatric Neurosurgical and Orthopedic Patients. Anesth Analg. 2020 May;130(5):1435-1444. PubMed PMID: 31397701
Peterson MB, Cohen MN, O'Neill BR, Garg S, Child J, Henthorn TK, Galinkin JG. Preoperative Vancomycin Administration for Surgical Site Prophylaxis: Plasma and Soft-Tissue Concentrations in Pediatric Neurosurgical and Orthopedic Patients. Anesth Analg. 2019 Aug 6. [Epub ahead of print] PubMed PMID: 31397701
Van Hove JLK, Freehauf CL, Ficicioglu C, Pena LDM, Moreau KL, Henthorn TK, Christians U, Jiang H, Cowan TM, Young SP, Hite M, Friederich MW, Stabler SP, Spector EB, Kronquist KE, Thomas JA, Emmett P, Harrington MJ, Pyle L, Creadon-Swindell G, Wempe MF, MacLean KN. Biomarkers of oxidative stress, inflammation, and vascular dysfunction in inherited cystathionine ß-synthase deficient homocystinuria and the impact of taurine treatment in a phase 1/2 human clinical trial. J Inherit Metab Dis. 2019 May;42(3):424-437. PubMed PMID: 30873612
Henthorn TK, Olofsen E. Where's the Beef?: How Much Can We Skimp on Pharmacokinetic-Pharmacodynamic Data?. Anesthesiology. 2019 Feb;130(2):186-188. PubMed PMID: 30589650
Henthorn TK, Avram MJ, Dahan A, Gustafsson LL, Persson J, Krejcie TC, Olofsen E. Combined Recirculatory-compartmental Population Pharmacokinetic Modeling of Arterial and Venous Plasma S( ) and R(-) Ketamine Concentrations. Anesthesiology. 2018 Aug;129(2):260-270. PubMed PMID: 29771709
Henthorn TK, Mikulich-Gilbertson SK. µ-Opioid Receptor Agonists: Do They Have Utility in the Treatment of Acute Pain?. Anesthesiology. 2018 May;128(5):867-870. PubMed PMID: 29543630
Jonkman K, Duma A, Olofsen E, Henthorn T, van Velzen M, Mooren R, Siebers L, van den Beukel J, Aarts L, Niesters M, Dahan A. Pharmacokinetics and Bioavailability of Inhaled Esketamine in Healthy Volunteers. Anesthesiology. 2017 Oct;127(4):675-683. PubMed PMID: 28759464
Klawitter J, Sempio C, Mörlein S, De Bloois E, Klepacki J, Henthorn T, Leehey MA, Hoffenberg EJ, Knupp K, Wang GS, Hopfer C, Kinney G, Bowler R, Foreman N, Galinkin J, Christians U, Klawitter J. An Atmospheric Pressure Chemical Ionization MS/MS Assay Using Online Extraction for the Analysis of 11 Cannabinoids and Metabolites in Human Plasma and Urine. Ther Drug Monit. 2017 Oct;39(5):556-564. PubMed PMID: 28640062