Matthew Jackman, PhD

Publications

• Jackman MR, Steig A, Higgins JA, Johnson GC, Fleming-Elder BK, Bessesen DH, MacLean PS. Weight regain after sustained weight reduction is accompanied by suppressed oxidation of dietary fat and adipocyte hyperplasia. Am J Physiol Regul Integr Comp Physiol. 2008 Apr;294(4):R1117-29. Epub 2008 Feb 20.
• Jackman MR, Ravussin E, Rowe MJ, Pratley R, Milner MR, Willis WT. Effect of a polymorphism in the ND1 mitochondrial gene on human skeletal muscle mitochondrial function. Obesity (Silver Spring). 2008 Feb;16(2):363-8.
• Dietary Fat is Trafficked to Small Adipocytes During Weight Regain Matthew Jackman, Amy Steig, Erin D. Giles, Nicole Stob, Ginger Johnson, Brooke Fleming, Rachel Lindstrom, Janine Higgins, Chris Erickson, Robert H. Eckel, Paul S. MacLean
• Cytokine Profiling of Lean and Obese Rats in a Model of Postmenopausal Breast Cancer Erin D. Giles, Ginger Johnson, Shauntae M. McDaniel, Brooke Fleming, Kaitlyn Gilman, Anna Andrianakos, Matthew Jackman, Kenneth Shroyer, Pepper Schedin, Paul S. MacLean
• Surprising Link Between the Energetics of Weight Gain and the Progression of Mammary Tumors in a Model of Postmenopausal Obesity and Breast Cancer. PS MacLean, ED Giles, G Johnson, S McDaniel, B Fleming, K Gilman, A Andrianakos, M Jackman, K Shroyer, P Schedin.
• Regular exercise after weight loss reduces the trafficking of dietary fat to adipose tissue during weight regain. A Steig, M Jackman, G Johnson, B Fleming, E Melanson, H Wyatt, J Higgins, J Hill, R Eckel, PS MacLean.
• Regular exercise attenuates the metabolic drive to regain weight after long-term weight loss. MacLean PS, Higgins JA, Wyatt HR, Melanson EL, Johnson GC, Jackman MR, Giles ED, Brown IE, Hill JO. Am J Physiol Regul Integr Comp Physiol. 2009 Sep;297(3):R793-802.
• A Surprising Link Between the Energetics of Ovariectomy-induced Weight Gain and Mammary Tumor Progression in Obese Rats. Maclean PS, Giles ED, Johnson GC, McDaniel SM, Fleming-Elder BK, Gilman KA, Andrianakos AG, Jackman MR, Shroyer KR, Schedin PJ. Obesity (Silver Spring). 2009 Oct 1. [Epub ahead of print]
• Energy expenditure in obesity prone and obesity resistant rats before and after the introduction of a high fat diet. Jackman MR, MacLean PS, Bessesen DH. Am J Physiol Regul Integr Comp Physiol.
• Giles ED, Jackman MR, Johnson GC, Schedin PJ, Houser JL, MacLean PS. Effect of the estrous cycle and surgical ovariectomy on energy balance, fuel utilization, and physical activity in lean and obese female rats. Am J Physiol Regul Integr Comp Physiol. 2010 Dec; 299(6):R1634-42. Epub 2010 Oct 6.
• Jackman, MR, MacLean, P.S., and D.H.Bessesen. Energy Expenditure in Obesity Prone and Obesity Resistant Rats Before and After the Introduction of a High Fat Diet. Am J Physiol Regul Integr Comp Physiol, 2010 Oct;299(4):R1097-105. Epub 2010 Aug 4.
• MacLean, P.S., Higgins, J.A., Wyatt, H., Melanson, E., Johnson, G.C., Jackman, MR, Giles, E.D., Brown, I., and Hill, J.O. “Regular Exercise Attenuates the Metabolic Drive to Regain Weight After Long Term Weight Loss. Am J Physiol Regul Integr Comp Physiol, Sep;297(3):R793-802, 2009
• Ishimoto, T, Lanaspa, MA, Le, MT, Garcia, GE, Diggle, CP, MacLean, PS, Jackman, MR, Asipu, A, Roncal, C, Kosugi, K, Rivard, CJ, Maruyama, S, Rodriguez-Iturbe, B, Sanchez-Lozada, LG, Bonthron, DT, Sautin, YY, and RJ Johnson. Opposing Effects of Fructokinase C and A Isoforms on Fructose-Induced Metabolic Syndrome in Mice. Proc Natl Acad Sci U S A. 2012 Feb 27. [Epub ahead of print]
• Young CD, Lewis AS, Rudolph MC, Ruehle MD, Jackman MR, Yun, UJ, Ilkun, O, Pereira, R., Abel, ED, Anderson, SM. Modulation of Glucose Transporter 1 (GLUT1) Expression Levels Alters Mouse Mammary Tumor Cell Growth In Vitro and In Vivo. PLoS One. 2011;6(8):e23205. Epub 2011 Aug 3.
• Maclean PS, Bergouignan A, Cornier MA, Jackman MR. Biology's Response to Dieting: the Impetus for Weight Regain. Am J Physiol Regul Integr Comp Physiol. 2011 Sep;301(3):R581-600. Epub 2011 Jun 15.
• Steig AJ, Jackman MR, Giles ED, Higgins JA, Johnson GC, Mahan C, Melanson EL, Wyatt HR, Eckel RH, Hill JO, Maclean PS. Exercise reduces appetite and traffics excess nutrients away from energetically efficient pathways of lipid deposition during the early stages of weight regain. Am J Physiol Regul Integr Comp Physiol. 2011 Sep;301(3):R656-67. Epub 2011 Jun 29.
• Higgins JA, Jackman MR, Brown IL, Johnson GC, Steig A, Wyatt HR, Hill JO, MacLean, PS. Resistant starch and exercise independently attenuate weight regain on a high fat diet in a rat model of obesity. Nutr Metab (Lond). 2011 Jul 7;8:49.
• Wahlig JL, Bales ES, Jackman MR, Johnson GC, McManaman JL, Maclean PS. Impact of High Fat Diet and Obesity on Energy Balance and Fuel Utilization During the Metabolic Challenge of Lactation. Obesity (Silver Spring). 2012 Jan;20(1):65-75. doi: 10.1038/oby.2011.196. Epub 2011 Jun 30.
• Perilipin-2 Null Mice are Protected Against Diet-Induced Obesity, Adipose Inflammation and Fatty Liver Disease. McManaman JL, Bales ES, Orlicky DJ, Jackman M, Maclean PS, Cain S, Crunk AE, Mansur A, Graham CE, Bowman TA, Greenberg AS. J Lipid Res. 2013 Feb 12. [Epub ahead of print]
• Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice. Ishimoto T, Lanaspa MA, Le MT, Garcia GE, Diggle CP, Maclean PS, Jackman MR, Asipu A, Roncal-Jimenez CA, Kosugi T, Rivard CJ, Maruyama S, Rodriguez-Iturbe B, Sánchez-Lozada LG, Bonthron DT, Sautin YY, Johnson RJ. Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4320-5. doi: 10.1073/pnas.1119908109. Epub 2012 Feb 27.
• Impact of high-fat diet and obesity on energy balance and fuel utilization during the metabolic challenge of lactation. Wahlig JL, Bales ES, Jackman MR, Johnson GC, McManaman JL, Maclean PS. Obesity (Silver Spring). 2012 Jan;20(1):65-75. doi: 10.1038/oby.2011.196. Epub 2011 Jun 30.
• Crunk AE, Monks J, Murakami A, Jackman M, Maclean PS, Ladinsky M, Bales ES, Cain S, Orlicky DJ, McManaman JL. Dynamic regulation of hepatic lipid droplet properties by diet. PLoS One. 2013;8(7):e67631. PubMed PMID: 23874434
• McManaman JL, Bales ES, Orlicky DJ, Jackman M, MacLean PS, Cain S, Crunk AE, Mansur A, Graham CE, Bowman TA, Greenberg AS. Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease. J Lipid Res. 2013 May;54(5):1346-59. PubMed PMID: 23402988
• Morris EM, Jackman MR, Meers GM, Johnson GC, Lopez JL, MacLean PS, Thyfault JP. Reduced hepatic mitochondrial respiration following acute high-fat diet is prevented by PGC-1a overexpression. Am J Physiol Gastrointest Liver Physiol. 2013 Dec;305(11):G868-80. PubMed PMID: 24091599
• Ishimoto T, Lanaspa MA, Rivard CJ, Roncal-Jimenez CA, Orlicky DJ, Cicerchi C, McMahan RH, Abdelmalek MF, Rosen HR, Jackman MR, MacLean PS, Diggle CP, Asipu A, Inaba S, Kosugi T, Sato W, Maruyama S, Sánchez-Lozada LG, Sautin YY, Hill JO, Bonthron DT, Johnson RJ. High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase. Hepatology. 2013 Nov;58(5):1632-43. PubMed PMID: 23813872
• Irwin DC, Garat CV, Crossno JT Jr, MacLean PS, Sullivan TM, Erickson PF, Jackman MR, Harral JW, Reusch JE, Klemm DJ. Obesity-related pulmonary arterial hypertension in rats correlates with increased circulating inflammatory cytokines and lipids and with oxidant damage in the arterial wall but not with hypoxia. Pulm Circ. 2014 Dec;4(4):638-53. PubMed PMID: 25610600
• Morris EM, Jackman MR, Johnson GC, Liu TW, Lopez JL, Kearney ML, Fletcher JA, Meers GM, Koch LG, Britton SL, Rector RS, Ibdah JA, MacLean PS, Thyfault JP. Intrinsic aerobic capacity impacts susceptibility to acute high-fat diet-induced hepatic steatosis. Am J Physiol Endocrinol Metab. 2014 Aug 15;307(4):E355-64. PubMed PMID: 24961240
• Saben JL, Bales ES, Jackman MR, Orlicky D, MacLean PS, McManaman JL. Maternal obesity reduces milk lipid production in lactating mice by inhibiting acetyl-CoA carboxylase and impairing fatty acid synthesis. PLoS One. 2014;9(5):e98066. PubMed PMID: 24849657
• Bergouignan A, Kealey EH, Schmidt SL, Jackman MR, Bessesen DH. Twenty-four hour total and dietary fat oxidation in lean, obese and reduced-obese adults with and without a bout of exercise. PLoS One. 2014;9(4):e94181. PubMed PMID: 24714529
• Hernandez TL, Bessesen DH, Cox-York KA, Erickson CB, Law CK, Anderson MK, Wang H, Jackman MR, Van Pelt RE. Femoral lipectomy increases postprandial lipemia in women. Am J Physiol Endocrinol Metab. 2015 Jul 1;309(1):E63-71. PubMed PMID: 25968576
• MacLean PS, Higgins JA, Giles ED, Sherk VD, Jackman MR. The role for adipose tissue in weight regain after weight loss. Obes Rev. 2015 Feb;16 Suppl 1:45-54. PubMed PMID: 25614203
• Bessesen DH, Cox-York KA, Hernandez TL, Erickson CB, Wang H, Jackman MR, Van Pelt RE. Postprandial triglycerides and adipose tissue storage of dietary fatty acids: impact of menopause and estradiol. Obesity (Silver Spring). 2015 Jan;23(1):145-53. PubMed PMID: 25354893
• A Simple Hydraulic Analog Model of Oxidative Phosphorylation WT Willis, MR Jackman, JI Messer, S Kuzmiak-Glancy, and B Glancy
• Frank DN, Bales ES, Monks J, Jackman MJ, MacLean PS, Ir D, Robertson CE, Orlicky DJ, McManaman JL. Perilipin-2 Modulates Lipid Absorption and Microbiome Responses in the Mouse Intestine. PLoS One. 2015;10(7):e0131944. PubMed PMID: 26147095
• Giles ED, Jackman MR, MacLean PS. Modeling Diet-Induced Obesity with Obesity-Prone Rats: Implications for Studies in Females.Front Nutr. 2016 Nov 24;3:50. eCollection 2016
• Giles ED, Steig AJ, Jackman MR, Higgins JA, Johnson GC, Lindstrom RC, MacLean PS. Exercise Decreases Lipogenic Gene Expression in Adipose Tissue and Alters Adipocyte Cellularity during Weight Regain After Weight Loss. Front Physiol. 2016 Feb 10;7:32. doi: 10.3389/fphys.2016.00032.
• Willis WT, Jackman MR, Messer JI, Kuzmiak-Glancy S, Glancy B. A Simple Hydraulic Analog Model of Oxidative Phosphorylation. Willis WT, Jackman MR, Messer JI, Kuzmiak-Glancy S, Glancy B. Med Sci Sports Exerc. 2016 Jun;48(6):990-1000. doi: 10.1249/MSS.0000000000000884. PMID: 26807634
• Rudolph MC, Jackman MR, Presby DM, Houck JA, Webb PG, Johnson GC, Soderborg TK, de la Houssaye BA, Yang IV, Friedman JE, MacLean PS. Low Neonatal Plasma N-6/N-3 Pufa Ratios Regulate Offspring Adipogenic Potential and Condition Adult Obesity Resistance. Diabetes. 2017 Nov 14. [Epub ahead of print] PubMed PMID: 29138256
• Sherk VD, Jackman MR, Giles ED, Higgins JA, Foright RM, Presby DM, Johnson GC, Houck JA, Houser JL, Oljira R, MacLean PS. Prior weight loss exacerbates the biological drive to gain weight after the loss of ovarian function. Physiol Rep. 2017 May;5(10). PubMed PMID: 28533263
• Foright RM, Presby DM, Sherk VD, Kahn D, Checkley LA, Giles ED, Bergouignan A, Higgins JA, Jackman MR, Hill JO, MacLean PS. Is regular exercise an effective strategy for weight loss maintenance?. Physiol Behav. 2018 Jan 27. [Epub ahead of print] PubMed PMID: 29382563
• Monks J, Orlicky DJ, Stefanski AL, Libby AE, Bales ES, Rudolph MC, Johnson GC, Sherk VD, Jackman MR, Williamson K, Carlson NE, MacLean PS, McManaman JL. Maternal obesity during lactation may protect offspring from high fat diet-induced metabolic dysfunction. Nutr Diabetes. 2018 Apr 25;8(1):18. PubMed PMID: 29695710
• Perreault L, Newsom SA, Strauss A, Kerege A, Kahn DE, Harrison KA, Snell-Bergeon JK, Nemkov T, D'Alessandro A, Jackman MR, MacLean PS, Bergman BC. Intracellular localization of diacylglycerols and sphingolipids influences insulin sensitivity and mitochondrial function in human skeletal muscle. JCI Insight. 2018 Feb 8;3(3). [Epub ahead of print] PubMed PMID: 29415895
• Foright RM, Presby DM, Sherk VD, Kahn D, Checkley LA, Giles ED, Bergouignan A, Higgins JA, Jackman MR, Hill JO, MacLean PS. Is regular exercise an effective strategy for weight loss maintenance?. Physiol Behav. 2018 May 1;188:86-93. PubMed PMID: 29382563
• Rudolph MC, Jackman MR, Presby DM, Houck JA, Webb PG, Johnson GC, Soderborg TK, de la Houssaye BA, Yang IV, Friedman JE, MacLean PS. Low Neonatal Plasma n-6/n-3 PUFA Ratios Regulate Offspring Adipogenic Potential and Condition Adult Obesity Resistance. Diabetes. 2018 Apr;67(4):651-661. PubMed PMID: 29138256
• Presby DM, Checkley LA, Jackman MR, Higgins JA, Jones KL, Giles ED, Houck JA, Webb PG, Steig AJ, Johnson GC, Rudolph MC, MacLean PS. Regular exercise potentiates energetically expensive hepatic de novo lipogenesis during early weight regain. Am J Physiol Regul Integr Comp Physiol. 2019 Nov 1;317(5):R684-R695. PubMed PMID: 31553623
• Sherk VD, Jackman MR, Higgins JA, Giles ED, Foright RM, Presby DM, Carpenter RD, Johnson GC, Oljira R, Houck JA, Maclean PS. Impact of Exercise and Activity on Weight Regain and Musculoskeletal Health Post-Ovariectomy. Med Sci Sports Exerc. 2019 Dec;51(12):2465-2473. PubMed PMID: 31274683
• Presby DM, Jackman MR, Rudolph MC, Sherk VD, Foright RM, Houck JA, Johnson GC, Orlicky DJ, Melanson EL, Higgins JA, MacLean PS. Compensation for cold-induced thermogenesis during weight loss maintenance and regain. Am J Physiol Endocrinol Metab. 2019 May 1;316(5):E977-E986. PubMed PMID: 30912962
• Presby DM, Rudolph MC, Sherk VD, Jackman MR, Foright RM, Jones KL, Houck JA, Johnson GC, Higgins JA, Neufer PD, Eckel RH, MacLean PS. Lipoprotein Lipase Overexpression in Skeletal Muscle Attenuates Weight Regain by Potentiating Energy Expenditure. Diabetes. 2021 Feb 3. [Epub ahead of print] PubMed PMID: 33536195
• Foright RM, Johnson GC, Kahn D, Charleston CA, Presby DM, Bouchet CA, Wellberg EA, Sherk VD, Jackman MR, Greenwood BN, MacLean PS. Compensatory eating behaviors in male and female rats in response to exercise training. Am J Physiol Regul Integr Comp Physiol. 2020 Aug 1;319(2):R171-R183. PubMed PMID: 32551825
• Hopp K, Catenacci VA, Dwivedi N, Kline TL, Wang W, You Z, Nguyen DT, Bing K, Poudyal B, Johnson GC, Jackman MR, Miller M, Steele CN, Serkova NJ, MacLean PS, Nemenoff RA, Gitomer B, Chonchol M, Nowak KL. Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease. iScience. 2022 Jan 21;25(1):103697. PubMed PMID: 35059607
• Presby DM, Rudolph MC, Sherk VD, Jackman MR, Foright RM, Jones KL, Houck JA, Johnson GC, Higgins JA, Neufer PD, Eckel RH, MacLean PS. Lipoprotein Lipase Overexpression in Skeletal Muscle Attenuates Weight Regain by Potentiating Energy Expenditure. Diabetes. 2021 Apr;70(4):867-877. PubMed PMID: 33536195
• Gavin KM, Sullivan TM, Maltzahn JK, Jackman MR, Libby AE, MacLean PS, Kohrt WM, Majka SM, Klemm DJ. Hematopoietic Stem Cell-Derived Adipocytes Modulate Adipose Tissue Cellularity, Leptin Production and Insulin Responsiveness in Female Mice. Front Endocrinol (Lausanne). 2022;13:844877. PubMed PMID: 35721743
• Ward AV, Matthews SB, Fettig LM, Riley D, Finlay-Schultz J, Paul KV, Jackman M, Kabos P, MacLean PS, Sartorius CA. Estrogens and Progestins Cooperatively Shift Breast Cancer Cell Metabolism. Cancers (Basel). 2022 Mar 31;14(7). PubMed PMID: 35406548
• De Jong NP, Rudolph MC, Jackman MR, Sharp RR, Jones K, Houck J, Pan Z, Reusch JEB, MacLean PS, Bessesen DH, Bergouignan A. Short-Term Adaptations in Skeletal Muscle Mitochondrial Oxidative Capacity and Metabolic Pathways to Breaking up Sedentary Behaviors in Overweight or Obese Adults. Nutrients. 2022 Jan 20;14(3). PubMed PMID: 35276813
• Hopp K, Catenacci VA, Dwivedi N, Kline TL, Wang W, You Z, Nguyen DT, Bing K, Poudyal B, Johnson GC, Jackman MR, Miller M, Steele CN, Serkova NJ, MacLean PS, Nemenoff RA, Gitomer B, Chonchol M, Nowak KL. Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease. iScience. 2022 Jan 21;25(1):103697. PubMed PMID: 35059607