York Miller, MD

Professor, Medicine-Cvp-Pulmonary


Publications

  • Merrick, DT, Haney, J, Petrunich, S, Sugita, M, Miller, YE, Keith, RL, Kennedy, TC, Franklin, WA. Overexpression of vascular endothelial growth factor and its receptors in bronchial dysplasia demonstrated by quantitative PCR analysis. Lung Cancer 48:31-45, 2005.
  • Kennedy, TC, Franklin, WA, Prindiville, SA, Cook, R, Dempsey, EC, Keith, RL, Hirsch, FR, Merrick, TA, Shroyer, KR, Petty, TL, Byers, T, Bunn, PA Jr, Miller, YE. High prevalence of endobronchial malignancy in high risk patients with moderate dysplasia in sputum. Lung Cancer 49:187-191, 2005.
  • Miller, YE, Vu, K, Kennedy, TC, Hirsch, FR, Petty, TL, Bunn, PA, Keith, RL, Franklin, WA, Wolf, HJ, Prindiville, S, Byers, T. Lack of association between sputum atypia and chronic obstructive pulmonary disease mortality. Journal of Thoracic Oncology, in press, 2006.
  • Rahman SM, Shyr Y, Yildiz PB, Gonzalez AL, Li H, Zhang X, Chaurand P, Yanagisawa K, Slovis BS, Miller RF, Ninan M, Miller YE, Franklin WA, Caprioli RM, Carbone DP, Massion PP. Proteomic patterns of preinvasive bronchial lesions. American Journal of Respiratory and Critical Care Medicine 172:1556-1662, 2005.
  • Bradley, TD, Miller, YE, Martinez, FJ, Angus, DC, MacNee, WJ, Abraham, E. Interstitial lung disease, lung cancer, lung transplantation, pulmonary vascular disorders and sleep disordered breathing in AJRCCM in 2004. American Journal of Respiratory and Critical Care Medicine 171:675-685, 2005.
  • Miller, YE. Pathogenesis of lung cancer: 100 year report . American Journal of Respiratory Cell and Molecular Biology 33:216-223, 2005.
  • Keith, RL, Miller YE. Lung cancer: Genetics of risk and advances in chemoprevention. Current Opinion in Pulmonary Medicine 11:265-271, 2005.
  • Jett, JR, Miller, YE. Lung Cancer: Year in Review, 2005. American Journal of Respiratory and Critical Care Medicine, in press.
  • Nakachi I, Rice JL, Coldren CD, Edwards MG, Stearman RS, Glidewell SC, Varella-Garcia M, Franklin WA, Keith RL, Lewis MT, Gao B, Merrick DT, Miller YE, Geraci MW. Application of SNP microarrays to the genome-wide analysis of chromosomal instability in premalignant airway lesions. Cancer Prev Res (Phila). 2014 Feb;7(2):255-65. PubMed PMID: 24346345
  • Keith RL, Miller YE. Lung cancer chemoprevention: current status and future prospects. Nat Rev Clin Oncol. 2013 Jun;10(6):334-43. PubMed PMID: 23689750
  • Karoor V, Oka M, Walchak SJ, Hersh LB, Miller YE, Dempsey EC. Neprilysin regulates pulmonary artery smooth muscle cell phenotype through a platelet-derived growth factor receptor-dependent mechanism. Hypertension. 2013 Apr;61(4):921-30. PubMed PMID: 23381789
  • Miller YE, Karoor V, Dempsey EC, Fagan KA. Sleep-disordered breathing, hypoxemia, and cancer mortality. Am J Respir Crit Care Med. 2013 Feb 1;187(3):330-1. PubMed PMID: 23378442
  • Mascaux C, Feser WJ, Lewis MT, Barón AE, Coldren CD, Merrick DT, Kennedy TC, Eckelberger JI, Rozeboom LM, Franklin WA, Minna JD, Bunn PA, Miller YE, Keith RL, Hirsch FR. Endobronchial miRNAs as biomarkers in lung cancer chemoprevention. Cancer Prev Res (Phila). 2013 Feb;6(2):100-8. PubMed PMID: 23268837
  • Welsh CH, Miller YE. Case Reports: Denver Veterans Affairs Medical Center experience with post-deployment dyspnea. In "Airborne Hazards", United States Army Borden Institute, 2013.
  • Mehan MR, Williams SA, Siegfried JM, Bigbee WL, Weissfeld JL, Wilson DO, Pass HI, Rom WN, Muley T, Meister M, Franklin W, Miller YE, Brody EN, Ostroff RM. Validation of a blood protein signature for non-small cell lung cancer. Clin Proteomics. 2014;11(1):32. PubMed PMID: 25114662
  • Nakachi I, Rice JL, Coldren CD, Edwards MG, Stearman RS, Glidewell SC, Varella-Garcia M, Franklin WA, Keith RL, Lewis MT, Gao B, Merrick DT, Miller YE, Geraci MW. Application of SNP microarrays to the genome-wide analysis of chromosomal instability in premalignant airway lesions. Cancer Prev Res (Phila). 2014 Feb;7(2):255-65. PubMed PMID: 24346345
  • Krefft S, Rose C, Nawaz S, Miller YE. Deployment related lung disease. Federal Practitioner, in press.
  • Vachani A, Pass HI, Rom WN, Midthun DE, Edell ES, Laviolette M, Li X-J, Fong P-Y, Hunsucker SW, Hayward C, Mazzone PJ, Madtes DK, Miller YE, Walker MG, Shi J, Kearney P, Fang KC, Massion P. Validation of a multi-protein classifier to identify benign lung nodules. In press, Journal of Thoracic Oncology, 2015.
  • Merrick DT, Gao D, Miller YE, Keith RL, Baron AE, Feser W, Kennedy TC, Blatchford PJ, Braudrick S, Hirsch FR, Heasley L, Bunn PA Jr, Franklin WA. Persistence of Bronchial Dysplasia Is Associated with Development of Invasive Squamous Cell Carcinoma. Cancer Prev Res (Phila). 2016 Jan;9(1):96-104. PubMed PMID: 26542061
  • Vachani A, Pass HI, Rom WN, Midthun DE, Edell ES, Laviolette M, Li XJ, Fong PY, Hunsucker SW, Hayward C, Mazzone PJ, Madtes DK, Miller YE, Walker MG, Shi J, Kearney P, Fang KC, Massion PP. Validation of a multiprotein plasma classifier to identify benign lung nodules. J Thorac Oncol. 2015 Apr;10(4):629-37. PubMed PMID: 25590604
  • Krefft SD, Rose CS, Nawaz S, Miller YE. Deployment related lung disorders. Federal Practitioner 32 (10) 24S-31S.
  • Belinsky SA, Liechty KC, Gentry FD, Wolf HJ, Rogers J, Vu K, Haney J, Kennedy TC, Hirsch FR, Miller Y, Franklin WA*, Herman JG, Baylin SB, Bunn PA, Byers T. Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort. Cancer Res, in press, 2006.
  • Merrick DT*, Kittelson J, Winterhalder R, Kotantoulas G, Ingeberg S, Keith RL#, Kennedy TC, Miller YE, Franklin WA*, Hirsch FR. Analysis of C-erb-B1 (EGFR) and C-erb-B2 (HER2) expression in bronchial dysplasia: Evaluation of potential targets for chemoprevention of lung cancer. Clin Cancer Res, in press, 2006.
  • Wick MJ, Loomis ZL, Harral JW, Le M, Wehling CA, Miller YE, Dempsey EC. Protection against vascular leak in neprilysin transgenic mice with complex overexpression pattern. Transgenic Res. 2016 Dec;25(6):773-784. PubMed PMID: 27369050
  • Merrick DT, Gao D, Miller YE, Keith RL, Baron AE, Feser W, Kennedy TC, Blatchford PJ, Braudrick S, Hirsch FR, Heasley L, Bunn PA Jr, Franklin WA. Persistence of Bronchial Dysplasia Is Associated with Development of Invasive Squamous Cell Carcinoma. Cancer Prev Res (Phila). 2016 Jan;9(1):96-104. PubMed PMID: 26542061
  • Ghosh M, Miller YE, Nakachi I, Kwon JB, Barón AE, Brantley AE, Merrick DT, Franklin WA, Keith RL, Vandivier RW. Exhaustion of Airway Basal Progenitor Cells in Early and Established COPD. Am J Respir Crit Care Med. 2017 Dec 6. [Epub ahead of print] PubMed PMID: 29211494
  • Barón AE, Kako S, Feser WJ, Malinowski H, Merrick D, Garg K, Malkoski S, Pretzel S, Siegfried JM, Franklin WA, Miller Y, Wolf HJ, Varella-Garcia M. Clinical Utility of Chromosomal Aneusomy in Individuals at High Risk of Lung Cancer. J Thorac Oncol. 2017 Oct;12(10):1512-1523. PubMed PMID: 28634123
  • HAFE: The Story Behind. http://www.nicebikefilms.com/#/hafe-the-story-behind-2/. Auerbach P and Miller YE, narrators; Ketay S, filmmaker and producer.
  • Merrick DT, Edwards MG, Franklin WA, Sugita M, Keith RL, Miller YE, Friedman MB, Dwyer-Nield LD, Tennis MA, O'Keefe MC, Donald EJ, Malloy JM, van Bokhoven A, Wilson S, Koch PJ, O'Shea C, Coldren C, Orlicky DJ, Lu X, Baron AE, Hickey G, Kennedy TC, Powell R, Heasley L, Bunn PA, Geraci M, Nemenoff RA. Altered Cell-Cycle Control, Inflammation, and Adhesion in High-Risk Persistent Bronchial Dysplasia. Cancer Res. 2018 Sep 1;78(17):4971-4983. PubMed PMID: 29997230
  • Ghosh M, Miller YE, Nakachi I, Kwon JB, Barón AE, Brantley AE, Merrick DT, Franklin WA, Keith RL, Vandivier RW. Exhaustion of Airway Basal Progenitor Cells in Early and Established Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018 Apr 1;197(7):885-896. PubMed PMID: 29211494
  • Ghosh M, Miller YE, Vandivier RW. Reply to Sohal: Airway Basal Cell Reprogramming and Epithelial-Mesenchymal Transition: A Potential Key to Understanding Early Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018 Jun 15;197(12):1645-1646. PubMed PMID: 29385351
  • Miller Y, Keith R#, Hirsch F, Dempsey E, Franklin W*, Kennedy T. Natural history of untreated endobronchial carcinoma in situ. 11th World Conference on Lung Cancer, July 3-6, 2005, Barcelona, Spain. Lung Cancer 49(Suppl 2):S184 (Abstr #P-265), 2005.
  • Miller Y, Hyun D, Blatchford P, Lewis M, Keith R#, Kennedy T, Franklin W*, Kittelson J, Hirsch F. Ki67 proliferation index in endobronchial biopsies: association with lung cancer, airflow obstruction and smoking history. 11th World Conference on Lung Cancer, July 3-6, 2005, Barcelona, Spain. Lung Cancer 49(Suppl 2):S183 (Abstr #P-264), 2005.
  • Keith RL, Blatchford PJ, Merrick DT, Bunn PA Jr, Bagwell B, Dwyer-Nield LD, Jackson MK, Geraci MW, Miller YE. A Randomized Phase II Trial of Pioglitazone for Lung Cancer Chemoprevention in High-Risk Current and Former Smokers. Cancer Prev Res (Phila). 2019 Oct;12(10):721-730. PubMed PMID: 31308004
  • Warsavage T Jr, Xing F, Barón AE, Feser WJ, Hirsch E, Miller YE, Malkoski S, Wolf HJ, Wilson DO, Ghosh D. Quantifying the incremental value of deep learning: Application to lung nodule detection. PLoS One. 2020;15(4):e0231468. PubMed PMID: 32287288
  • Miller YE, Varella-Garcia M*, Jonsson S, Keith R#, Hirsch F, Merrick D*, Kennedy T, Franklin WA*. Endobronchial CIS: Aneuploidy reflects natural history of untreated lesions. Lung SPORE 2006 Winter Meeting, NCI Organ Systems Branch, January 25-26, 2006, Los Angeles, CA. Proceedings, Abstract #41, 2006.
  • Miller, YE, Vu, K, Kennedy, TC, Hirsch, FR, Petty, TL, Bunn, PA, Keith, RL, Franklin, WA, Wolf, HJ, Prindiville, S, Byers, T. Lack of association between sputum atypia and chronic obstructive pulmonary disease mortality. Journal of Thoracic Oncology 1:302-307, 2006.
  • Janssen WJ, Bierig, LN, Beuther DA, Miller, YE. Stridor in a 47 year old man with inflammatory bowel disease. Chest 129:1100-1106, 2006.
  • Merrick DT, Kittleson J, Winterhalder R, Kotantoulas G, Ingeberg S, Keith RL, Kennedy TC, Miller YE, Franklin WA, Hirsch FR. Analysis of cErbB1/epidermal growth factor receptor and cErbB2/HER2 expression in bronchial dysplasia: evaluation of potential targets for chemoprevention of lung cancer. Clinical Cancer Research 12:2281-2288, 2006.
  • Belinsky SA, Liechty KC, Gentry FD, Wolf HJ, Rogers J, Vu K, Haney J, Kennedy TC, Hirsch FR, Miller Y, Franklin WA, Herman JG, Baylin SB, Bunn PA, Byers T. Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high risk cohort. Cancer Research 66:3338-3344, 2006.
  • Jett JR, Miller YE. Update in lung cancer 2005. American Journal of Respiratory and Critical Care Medicine 173:695-697, 2006.
  • Jett JR, Miller YE. Update in lung cancer 2005. American Journal of Respiratory and Critical Care Medicine 173:695-697, 2006.
  • Miller YE, Keith RL. Inhaled corticosteroids and lung cancer chemoprevention. American Journal of Respiratory and Critical Care Medicine, in press, 2007.
  • Varella-Garcia M, Chen L, Powell RL, Hirsch FR, Kennedy TC, Keith R, Miller YE, Mitchell JD, Franklin WA. Spectral karyotyping detects chromosome damage in bronchial cells of smokers and patients with cancer. American Journal of Respiratory and Critical Care Medicine 176: 505-512, 2007.
  • Miller YE, Blatchford P, Lewis M, Hyun DS, Keith RL, Kennedy TC, Wolf H, Byers T, Bunn PA, Franklin WA, Hirsch FR, Kittelson JM. Bronchial epithelial proliferation measured by Ki-67 is related to current smoking and sex but not to lung cancer or chronic obstructive pulmonary disease. Cancer, Epidemiology, Biomarkers and Prevention 16:2425-2431, 2007.
  • Jonsson S, Varella-Garcia M, Miller YE, Wolf HJ, Byers T, Bruadrick S, Kiatsimkul P, Lewis M, Kennedy TC, Keith RL, Bjornsson J, McWilliams A, Lam S, Hirsch FR, Franklin WA. Chromosomal aneusomy in bronchial high grade lesions associated with invasive lung cancer. American Journal of Respiratory and Critical Care Medicine 177:342-347, 2008.
  • Byers T, Wolf, HJ, Franklin, WA, Braudrick S, Merrick DT, Shroyer KR, Hirsch FR, Zeng C, Baron AE, Bunn PA, Miller YE, Kennedy TC. Sputum cytologic atypia predicts incident lung cancer: Defining latency and histologic specificity. Cancer, Epidemiology, Biomarkers and Prevention 17:158-162, 2008.
  • Gingo MR, Silveira LJ, Miller, YE, Friedlander AL, Cosgrove GP, Chan ED, Maier, LA, Bowler RP. Tumor necrosis factor gene polymorphisms are associated with chronic obstructive pulmonary disease. In press, European Respiratory Journal, 2008
  • Miller YE, Keith RL. Inhaled corticosteroids and lung cancer chemoprevention. American Journal of Respiratory and Critical Care Medicine 175:636-637, 2007.
  • Keith RL, Jonsson S, Miller YE. COPD, the last chapter—Lung Cancer. In Chronic Obstructive Lung Diseases, ed. Voelkel, NF and MacNee, W. 2007.
  • Byers T, Wolf HJ, Franklin WA, Braudrick S, Merrick DT, Shroyer KR, Hirsch FR, Zeng C, Baron AE, Bunn PA, Miller YE, Kennedy TC. Sputum cytologic atypia predicts incident lung cancer: Defining latency and histologic specificity. Cancer, Epidemiology, Biomarkers and Prevention 17:158-162, 2008.
  • Jonsson S, Varella-Garcia M, Miller YE, Wolf HJ, Byers T, Bruadrick S, Kiatsimkul P, Lewis M, Kennedy TC, Keith RL, Bjornsson J, McWilliams A, Lam S, Hirsch FR, Franklin WA. Chromosomal aneusomy in bronchial high grade lesions associated with invasive lung cancer. American Journal of Respiratory and Critical Care Medicine 177:342-347, 2008.
  • Gingo MR, Silveira LJ, Miller YE, Friedlander AL, Cosgrove GP, Chan ED, Maier LA, Bowler RP. Tumor necrosis factor gene polymorphisms are associated with chronic obstructive pulmonary disease. European Respiratory Journal 31:1005-1012, 2008.
  • Minowada G and Miller YE. Overexpression of Sprouty2 in mouse lung epithelium inhibits urethane induced tumorigenesis. American Journal of Respiratory Cell and Molecular Biology 40:31-37, 2009.
  • Kelly K, Kittelson JM, Franklin WA, Kennedy TC, Klein C, Lewis M, Jackson MK, Holte J, Keith RL, Hirsch FR, Bunn PA, Miller YE. A randomized phase II chemoprevention trial evaluating the effects of 13 cis retinoic acid with or without alpha tocopherol or observation on bronchial epithelium in subjects at high risk for lung cancer. In press, Cancer Prevention Research, 2009.
  • Dempsey EC, Tallman D, Wehling CA, Karoor V, Wick MJ, Walchak SJ, Barr EJ, Laudi S, Le M, Oka M, Cool CD, Fagan FA, Klemm DJ, Hersh LB, Gerard NP, Gerard C, Miller, YE. Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia. In press, American Journal of Pathology.
  • Edell E, Lam S, Pass H, Miller YE, Sutedja TG, Kennedy TC, Loewen G, et al. Detection and localization of intraepithelial neoplasia and invasive carcinoma using fluorescence-reflectance bronchoscopy: An international, multi-center clinical trial. Journal of Thoracic Oncology 4:49-54, 2009.
  • Erickson TM, Koeppe JR, Miller YE, Stuart RW, Camidge DR. Bronchioloalveolar carcinoma presenting as chronic progressive pulmonary infiltrates in a woman with HIV: A diagnosis worth making. Journal of Thoracic Oncology 3: 1353-1355, 2008.
  • Keith RL, Jonsson S, Miller YE. COPD, the last chapter—Lung Cancer. In Chronic Obstructive Lung Diseases, ed. Voelkel, NF and MacNee, W. 2008.
  • Miller YE. Minimizing Unintended Consequences of Detecting Lung Nodules by CT. American Journal of Respiratory and Critical Care Medicine 178:891-892, 2008.
  • Minowada G and Miller YE. Overexpression of Sprouty2 in mouse lung epithelium inhibits urethane induced tumorigenesis. American Journal of Respiratory Cell and Molecular Biology 40:31-37, 2009.
  • Dempsey EC, Tallman D, Wehling CA, Karoor V, Wick MJ, Walchak SJ, Barr EJ, Laudi S, Le M, Oka M, Cool CD, Fagan FA, Klemm DJ, Hersh LB, Gerard NP, Gerard C, Miller, YE. Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia. American Journal of Pathology 174:782-796, 2009.
  • Kelly K, Kittelson JM, Franklin WA, Kennedy TC, Klein C, Lewis M, Jackson MK, Holte J, Keith RL, Hirsch FR, Bunn PA, Miller YE. A randomized phase II chemoprevention trial evaluating the effects of 13 cis retinoic acid with or without alpha tocopherol or observation on bronchial epithelium in subjects at high risk for lung cancer. Cancer Prevention Research 2:440-449, 2009.
  • Massion PP, Zou Y, Kiatsimkul P, Uner H, Wolf HJ, Byers T, Jonsson S, Lam S, Hirsch F, Miller YE, Franklin WA, Varella-Garcia M. Recurrent genomic gains in preinvasive lesions as a biomarker of risk for lung cancer. PLoS One 4:e5611, 2009.
  • Edell E, Lam S, Pass H, Miller YE, Sutedja TG, Kennedy TC, Loewen G, Keith RL, Gazdar A. Detection and localization of intraepithelial neoplasia and invasive carcinoma using fluorescence-reflectance bronchoscopy: An international, multi-center clinical trial. Journal of Thoracic Oncology 4:49-54, 2009.
  • Oh S, Jin Q, Kim W, Kim ES, Yang YJ, Feng L, Behrens C, Prudkin L, Miller YE, Lee JJ, Lippman SM, Hong WK, Wistuba II, Lee HY. Elevated epithelial insulin like growth factor is a risk factor for lung cancer development. Cancer Research 69:7439-7348, 2009.
  • Keith RL, Karoor V, Mozer AB, Hudish TM, Le M, Miller, YE. Chemoprevention of murine lung cancer by gefitnib in combination with prostacyclin synthase overexpression. In press, Lung Cancer, 2010.
  • Karoor V, Le M, Merrick D, Dempsey EC, Miller YE. VEGFR-2 targeted chemoprevention of murine lung tumors. In press, Cancer Prevention Research, 2010.
  • Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: Clonal expansion and dissemination of mutant progenitor cells. In press, Journal of Thoracic Oncology, 2010.
  • Keith RL, Karoor V, Mozer AB, Hudish TM, Le M, Miller, YE. Chemoprevention of murine lung cancer by gefitnib in combination with prostacyclin synthase overexpression. Lung Cancer 70:37-42, 2010.
  • Karoor V, Le M, Merrick D, Dempsey EC, Miller YE. VEGFR-2 targeted chemoprevention of murine lung tumors. Cancer Prevention Research 3:1141-1147, 2010.
  • Varella-Garcia M, Schulte AP, Wolf HJ, Feser WJ, Zeng C, Braudrick S, Yin X, Hirsch FR, Kennedy TC, Keith RL, Baron AE, Belinsky SA, Miller YE, Byers T, Franklin WA. Chromosomal aneusomy in sputum, as detected by fluorescence in situ hybridization, predicts lung cancer incidence. Cancer Prevention Research 3(4):447-453, 2010.
  • Wick MJ, Buesing EJ, Wehling CA, Loomis ZL, Cool CD, Zamora MR, Miller YE, Colgan SP, Hersh LB, Voelkel NF, Dempsey EC. Decreased neprilysin and pulmonary vascular remodeling in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine 183:330-340, 2010.
  • Keith RL, Blatchford PJ, Kittelson J, Minna JD, Kelly K, Massion PP, Franklin WA, Mao J, Wilson DO, Merrick DM, Hirsch FR, Kennedy TC, Bunn PA, Geraci MW, Miller YE. Oral iloprost improves bronchial dysplasia in former smokers. In press, Cancer Prevention Research, 2011.
  • Ostroff RM, Bigbee WL, Franklin WA, Gold L, Mehan M, Miller YE, Pass HI, Rom WN, Siegfried JM, Stewart A, Walker JJ, Weissfeld, JL, Williams S, Zichi D, Brody JN. Unlocking biomarker discovery: Large scale application of aptamer proteomic technology for early detection of lung cancer. PLoS One 5:e150003, 2010.
  • Keith RL, Miller YE, Ghosh M, Franklin WA, Nakachi I, Merrick DT. Lung cancer: Premalignant biology and medical prevention. Semin Oncol. 2022 Feb 27. [Epub ahead of print] PubMed PMID: 35305831
  • Rafnar T, Sulem P, Besenbacher S, Gudbjartsson D, Zanon C, Gudmundsson J, Stacey S, Kostic J, Thorgeirsson T, Thorleifsson G, Bjarnason H, Skuladottir H, Gudbjartsson T, Isaksson H, Isla D, Heijden L, Feser W, Miller Y, Bunn P, Kong A, Wolf H, Franklin W, Mayordomo J, Kiemeney L, Jonsson S, Thorsteinsdottir U, Stefansson K. Genome-wide significant association between a sequence variant at 15q15.2 and lung cancer risk. In press, Cancer Research, 2010
  • Miller YE. Does unilateral DIPNECH provide clues to pathogenesis? Journal of Thoracic Oncology 5:761-762, 2010.
  • Wick MJ, Buesing EJ, Wehling CA, Loomis ZL, Cool CD, Zamora MR, Miller YE, Colgan SP, Hersh LB, Voelkel NF, Dempsey EC. Decreased neprilysin and pulmonary vascular remodeling in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine 183:330-340, 2011.
  • Keith RL, Blatchford PJ, Kittelson J, Minna JD, Kelly K, Massion PP, Franklin WA, Mao J, Wilson DO, Merrick DM, Hirsch FR, Kennedy TC, Bunn PA, Geraci MW, Miller YE. Oral iloprost improves bronchial dysplasia in former smokers. Cancer Prevention Research 4:793-802, 2011.
  • Miller YE, Ghosh M, Merrick DT, Kubala B, Szabo E, Bengtson L, Kocherginsky M, Helenowski IB, Benante K, Schering T, Kim J, Kim H, Ha D, Bergan RC, Khan SA, Keith RL. Phase Ib trial of inhaled iloprost for the prevention of lung cancer with predictive and response biomarker assessment. Front Oncol. 2023;13:1204726. PubMed PMID: 37711198
  • Rafnar T, Sulem P, Besenbacher S, Gudbjartsson D, Zanon C, Gudmundsson J, Stacey S, Kostic J, Thorgeirsson T, Thorleifsson G, Bjarnason H, Skuladottir H, Gudbjartsson T, Isaksson H, Isla D, Heijden L, Feser W, Miller Y, Bunn P, Kong A, Wolf H, Franklin W, Mayordomo J, Kiemeney L, Jonsson S, Thorsteinsdottir U, Stefansson K. Genome-wide significant association between a sequence variant at 15q15.2 and lung cancer risk. Cancer Research 71:1356-1361, 2011.
  • Egloff AM, Gaither Davis A, Shuai Y, Land S, Pilewski JM, Luketich JD, Landreneau R, Miller YE, Grandis JR, Siegfried JM. Gastrin-releasing peptide receptor expression in non-cancerous bronchial epithelia is associated with lung cancer: a case-control study. Respiratory Research 13:9, 2012.
  • 19. Rahman SM, Gonzalez AL, Li M, Seeley EH, Zimmerman LJ, Zhang XJ, Manier ML, Olson S, Shah RM, Miller A, Putnam JB, Miller YE, Franklin WA, Blot WJ, Carbone DP, Shyr Y, Caprioli RM, Massion PP. Lung cancer diagnosis from preinvasive lesions. Cancer Research 71:3009-3017, 2011. PMCID: PMC 3110721.
  • 50. Coldren CD, Miller, YE. Progressive endobronchial malignancy: Marked by original CIN. American Journal of Respiratory and Critical Care Medicine 184: 869-870, 2011.
  • Assante A, Lkhagvadorj K, Clambey ET, Danhorn T, Merrick DT, Keith RL, New ML, Degregori J, Miller YE, Ghosh M. Reduced Progenitor Function and Altered Immune Landscape Contribute to Field Cancerization of Lung Adenocarcinoma. Am J Respir Crit Care Med. 2023 Oct 15;208(8):903-905. PubMed PMID: 37639330
  • Jonsson S, Franklin WA, Varella-Garcia M, Kennedy TC, Merrick D, Matney KD, Oskarsdottir GN, Saemundsson A, Keith RL, Bunn PA, Miller YE. Prevalence, molecular markers, and outcome of bronchial squamous carcinoma in situ in high-risk subjects. APMIS. 2023 Oct;131(10):513-527. PubMed PMID: 37608782
  • 51. Rich EN, Miller, YE. Early detection and screening for lung cancer: A new era opens. Treatment Strategies-Oncology
  • Hill W, Lim EL, Weeden CE, Lee C, Augustine M, Chen K, Kuan FC, Marongiu F, Evans EJ Jr, Moore DA, Rodrigues FS, Pich O, Bakker B, Cha H, Myers R, van Maldegem F, Boumelha J, Veeriah S, Rowan A, Naceur-Lombardelli C, Karasaki T, Sivakumar M, De S, Caswell DR, Nagano A, Black JRM, Martínez-Ruiz C, Ryu MH, Huff RD, Li S, Favé MJ, Magness A, Suárez-Bonnet A, Priestnall SL, Lüchtenborg M, Lavelle K, Pethick J, Hardy S, McRonald FE, Lin MH, Troccoli CI, Ghosh M, Miller YE, Merrick DT, Keith RL, Al Bakir M, Bailey C, Hill MS, Saal LH, Chen Y, George AM, Abbosh C, Kanu N, Lee SH, McGranahan N, Berg CD, Sasieni P, Houlston R, Turnbull C, Lam S, Awadalla P, Grönroos E, Downward J, Jacks T, Carlsten C, Malanchi I, Hackshaw A, Litchfield K, DeGregori J, Jamal-Hanjani M, Swanton C. Lung adenocarcinoma promotion by air pollutants. Nature. 2023 Apr;616(7955):159-167. PubMed PMID: 37020004
  • Vijaya Karoor, Mysan Le, Daniel Merrick, Karen A. Fagan, Edward C. Dempsey, and York E. Miller, Alveolar Hypoxia Promotes Lung Tumor Growth Through A VEGFR-2 Dependent Mechanism
  • New ML, Hirsch EA, Feser WJ, Malkoski SP, Garg K, Miller YE, Baron AE. Differences in VA and Non-VA Pulmonary Nodules: All Evaluations Are not Created Equal. Clin Lung Cancer. 2023 Jul;24(5):407-414. PubMed PMID: 37012147
  • Egloff AM, Gaither Davis A, Shuai Y, Land S, Pilewski JM, Luketich JD, Landreneau R, Miller YE, Grandis JR, Siegfried JM. Gastrin-releasing peptide receptor expression in non-cancerous bronchial epithelia is associated with lung cancer: a case-control study. Respiratory Research 13:9, 2012.
  • Karoor V, Le M, Merrick D, Fagan KA, Dempsey EC, Miller YE. Alveolar hypoxia promotes murine lung tumor growth through a VEGFR-2/EGFR dependent mechanism. Cancer Prevention Research 5:1061-1071, 2012.
  • Peled N, Hakim M, Bunn PA Jr, Miller YE, Kennedy TC, Mattei J, Mitchell JD, Hirsch FR, Haick H. Non-invasive breath analysis of pulmonary nodules. Journal of Thoracic Oncology 7:1528-1533, 2012.
  • Mascaux C, Feser WJ, Lewis MT, Baron AE, Coldren CD, Merrick DT, Kennedy TC Eckelberger JI, Rozeboom LM, Franklin WA, Minna JD, Bunn PA, Miller YE, Keith RL, Hirsch FR. Cancer Prevention Research 2013. (Epub ahead of print)
  • Karoor V, Oka M, Walchak SJ, Hersh LB, Miller YE, Dempsey EC. Neprilysin regulates pulmonary artery smooth muscle cell phenotype through a platelet-derived growth factor receptor-dependent mechanism. Hypertension, 2013. (Epub ahead of print)
  • Keith, RL and Miller, YE. Lung cancer chemoprevention. In press, Nature Reviews Clinical Oncology, 2013.
  • Tuder RM, Kern JA, Miller, YE. Senescence in chronic obstructive pulmonary disease. Proceedings of the American Thoracic Society 9:62-63, 2012.
  • Miller YE, Karoor V, Dempsey EC, Fagan KA. Sleep-disordered breathing, hypoxemia and cancer mortality. American Journal of Respiratory and Critical Care Medicine 187:330-331, 2013.
  • Rich EN, Miller, YE. Early detection and screening for lung cancer: A new era opens. Treatment Strategies-Oncology, in press, 2013.
  • Hickey GA, Keith RM, Miller, YE. Common pathobiologic origins of chronic obstructive pulmonary disease and lung cancer: More than just a smoking gun. Lung Cancer Management 1:239-242, 2012.
  • Welsh CH, Miller YE. Denver Veterans Affairs Medical Center experience with post-deployment pulmonary disease. In press, 2013.

Specialty Information

Specialties
  • Pulmonary Disease, Board Certification