Samuel Dominguez, MD, PhD
Professor, Pediatrics-Infectious Diseases

Professional Titles

• Professor of Pediatrics

Research Interests

Teaching

Publications

• Park SY, Coufal NG, Dominguez SR, Farnaes L, Messacar K, Goldman FD. Gaps in diagnosing suspected infection in immunocompromised children with cancer: A systematic review. Pediatr Blood Cancer. 2023 Dec 7;:e30794. [Epub ahead of print] PubMed PMID: 38059641
• Butler M, Breazeale G, Mwangi E, Dowell E, Dominguez SR, Lamberth L, Hultén KG, Jung SA. Development and validation of a multiplex real-time PCR assay for detection and quantification of Streptococcus pneumoniae in pediatric respiratory samples. Microbiol Spectr. 2023 Nov 8;:e0211823. [Epub ahead of print] PubMed PMID: 37937989
• Ho EC, Cotter JM, Thomas J, Birkholz M, Dominguez SR. Factors Associated With Actionable Gastrointestinal Panel Results in Hospitalized Children. Hosp Pediatr. 2023 Dec 1;13(12):1115-1123. PubMed PMID: 37936503
• Nguyen-Tran H, Thompson C, Butler M, Miller KR, Pyle L, Jung S, Rogers S, Ng TFF, Routh J, Dominguez SR, Messacar K. Duration of Enterovirus D68 RNA Shedding in the Upper Respiratory Tract and Transmission among Household Contacts, Colorado, USA. Emerg Infect Dis. 2023 Nov;29(11):2315-2324. PubMed PMID: 37877582
• Ho EC, Cataldi JR, Silveira LJ, Birkholz M, Loi MM, Osborne CM, Dominguez SR. Outbreak of Invasive Group A Streptococcus in Children-Colorado, October 2022-April 2023. J Pediatric Infect Dis Soc. 2023 Oct 28;12(10):540-548. PubMed PMID: 37792995
• Frost HM, Jenkins TC, Sebastian T, Parker SK, Keith A, Kurtz M, Fletcher DR, Wilson ML, Dominguez SR. Reliability of nasopharyngeal PCR for the detection of otopathogens in children with uncomplicated acute otitis media compared to culture. Diagn Microbiol Infect Dis. 2023 Oct;107(2):116040. PubMed PMID: 37549633
• Nguyen-Tran H, Reno S, Mwangi E, Mentel M, Hengartner R, Dominguez SR, Messacar K, Jung SA. Qualitative detection of enterovirus D68 from PrimeStore® molecular transport medium: implications for home- and self-collection. Diagn Microbiol Infect Dis. 2023 Aug;106(4):115976. PubMed PMID: 37267740
• Rao S, Armistead I, Tyler A, Lensing M, Dominguez SR, Alden NB. Respiratory Syncytial Virus, Influenza, and Coronavirus Disease 2019 Hospitalizations in Children in Colorado During the 2021-2022 Respiratory Virus Season. J Pediatr. 2023 Sep;260:113491. PubMed PMID: 37201680
• Rao S, Armistead I, Messacar K, Alden NB, Schmoll E, Austin E, Dominguez SR. Shifting Epidemiology and Severity of Respiratory Syncytial Virus in Children During the COVID-19 Pandemic. JAMA Pediatr. 2023 Jul 1;177(7):730-732. PubMed PMID: 37184852
• O'Brien SC, Cole LD, Albanese BA, Mahon A, Knight V, Williams N, Severson R, Burakoff A, Alden NB, Dominguez SR. SARS-CoV-2 Seroprevalence Compared with Confirmed COVID-19 Cases among Children, Colorado, USA, May-July 2021. Emerg Infect Dis. 2023 May;29(5):929-936. PubMed PMID: 36972709
• Barnes M, Youngkin E, Zipprich J, Bilski K, Gregory CJ, Dominguez SR, Mumm E, McMahon M, Como-Sabetti K, Lynfield R, Chochua S, Onukwube J, Arvay M, Herlihy R. Notes from the Field: Increase in Pediatric Invasive Group A Streptococcus Infections - Colorado and Minnesota, October-December 2022. MMWR Morb Mortal Wkly Rep. 2023 Mar 10;72(10):265-267. PubMed PMID: 36893049
• Searns JB, Rice JD, Bertin KB, Birkholz M, Barganier LB, Creech CB, Downes KJ, Hubbell BB, Kronman MP, Rolsma SL, Sydney GI, O'Leary ST, Parker SK, Dominguez SR. Using Administrative Billing Codes to Identify Acute Musculoskeletal Infections in Children. Hosp Pediatr. 2023 Feb 1;13(2):182-195. PubMed PMID: 36601701
• Boster JM, Dominguez SR, Messacar K, Adams M, Weinberg A, Black JO, Feldman AG. Acute Liver Failure in a Child With Adenovirus Detected by PCR in the Explanted Liver. Pediatrics. 2023 Feb 1;151(2). PubMed PMID: 36691756
• Bonavia A, Dominguez SR, Dveksler G, Gagneten S, Howard M, Jeffers S, Qian Z, Smith MK, Thackray LB, Tresnan DB, Wentworth DE, Wessner DR, Williams RK, Miura TA. Kathryn V. Holmes: A Career of Contributions to the Coronavirus Field. Viruses. 2022 Jul 20;14(7). PubMed PMID: 35891553
• Windsor WJ, Lamb MM, Dominguez SR, Mistry RD, Rao S. Clinical characteristics and illness course based on pathogen among children with respiratory illness presenting to an emergency department. J Med Virol. 2022 Dec;94(12):6103-6110. PubMed PMID: 35882541
• Frost HM, Sebastian T, Keith A, Kurtz M, Dominguez SR, Parker SK, Jenkins TC. COVID-19 and Acute Otitis Media in Children: A Case Series. J Prim Care Community Health. 2022 Jan-Dec;13:21501319221082351. PubMed PMID: 35289210
• Messacar K, Palmer C, Gregoire L, Elliott A, Ackley E, Perraillon MC, Tyler KL, Dominguez SR. Clinical and Financial Impact of a Diagnostic Stewardship Program for Children with Suspected Central Nervous System Infection. J Pediatr. 2022 May;244:161-168.e1. PubMed PMID: 35150729
• Nguyen-Tran H, Park SW, Messacar K, Dominguez SR, Vogt MR, Permar S, Permaul P, Hernandez M, Douek DC, McDermott AB, Metcalf CJE, Grenfell B, Spaulding AB. Enterovirus D68: a test case for the use of immunological surveillance to develop tools to mitigate the pandemic potential of emerging pathogens. Lancet Microbe. 2022 Feb;3(2):e83-e85. PubMed PMID: 35036969
• Graff K, Dominguez SR, Messacar K. Metagenomic Next-Generation Sequencing for Diagnosis of Pediatric Meningitis and Encephalitis: A Review. J Pediatric Infect Dis Soc. 2021 Dec 24;10(Supplement_4):S78-S87. PubMed PMID: 34951470
• Cole LD, Osborne CM, Silveira LJ, Rao S, Lockwood JM, Kunkel MJ, MacBrayne CE, Heizer HR, Anderson MS, Jone PN, Dominguez SR. IVIG Compared to IVIG Plus Infliximab in Multisystem Inflammatory Syndrome in Children. Pediatrics. 2021 Sep 22. [Epub ahead of print] PubMed PMID: 34814192
• Burney JA, DeHaan LL, Shimizu C, Bainto EV, Newburger JW, DeBiasi RL, Dominguez SR, Portman MA, Melish M, Bratincsak A, Fabi M, Corinaldesi E, Yu JJ, Gee P, Kitano N, Tremoulet AH, Cayan DR, Burns JC. Temporal clustering of Kawasaki disease cases around the world. Sci Rep. 2021 Nov 19;11(1):22584. PubMed PMID: 34799633
• Dolan SA, Mulcahy Levy J, Moss A, Pearce K, Butler M, Jung S, Dominguez SR, Mwangi E, Maloney K, Rao S. SARS-CoV-2 persistence in immunocompromised children. Pediatr Blood Cancer. 2021 Dec;68(12):e29277. PubMed PMID: 34453477
• Graff KE, Windsor WJ, Calvimontes DM, Melgar MA, Galvez N, Rivera JG, Dominguez SR, Asturias EJ, Gordillo MR. Antimicrobial Resistance Trends at a Pediatric Hospital in Guatemala City, 2005-2019. J Pediatric Infect Dis Soc. 2021 Aug 26. [Epub ahead of print] PubMed PMID: 34437683
• Graff KE, Palmer C, Anarestani T, Velasquez D, Hamilton S, Pretty K, Parker S, Dominguez SR. Clinical Impact of the Expanded BioFire Blood Culture Identification 2 Panel in a U.S. Children's Hospital. Microbiol Spectr. 2021 Sep 3;9(1):e0042921. PubMed PMID: 34431685
• Ackley ER, Tchou MJ, Press CA, Parker SK, Dominguez SR, Gaensbauer J, Messacar K. AKI In Suspected Meningitis/Encephalitis May Be "Avoidable Kidney Injury". Hosp Pediatr. 2021 Aug;11(8):e167-e169. PubMed PMID: 34244336
• Rao S, Lamb MM, Moss A, Mistry RD, Grice K, Ahmed W, Santos-Cantu D, Kitchen E, Patel C, Ferrari I, Dominguez SR. Effect of Rapid Respiratory Virus Testing on Antibiotic Prescribing Among Children Presenting to the Emergency Department With Acute Respiratory Illness: A Randomized Clinical Trial. JAMA Netw Open. 2021 Jun 1;4(6):e2111836. PubMed PMID: 34086034
• Cotter JM, Thomas J, Birkholz M, Ambroggio L, Holstein J, Dominguez SR. Clinical Impact of a Diagnostic Gastrointestinal Panel in Children. Pediatrics. 2021 May;147(5). PubMed PMID: 33837134
• Graff K, Smith C, Silveira L, Jung S, Curran-Hays S, Jarjour J, Carpenter L, Pickard K, Mattiucci M, Fresia J, McFarland EJ, Dominguez SR, Abuogi L. Risk Factors for Severe COVID-19 in Children. Pediatr Infect Dis J. 2021 Apr 1;40(4):e137-e145. PubMed PMID: 33538539
• Shane AL, Sato AI, Kao C, Adler-Shohet FC, Vora SB, Auletta JJ, Nachman S, Raabe VN, Inagaki K, Akinboyo IC, Woods C, Alsulami AO, Kainth MK, Santos RP, Espinosa CM, Burns JE, Cunningham CK, Dominguez SR, Martinez BL, Zhu F, Crews J, Kitano T, Saiman L, Kotloff K. A Pediatric Infectious Diseases Perspective of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Novel Coronavirus Disease 2019 (COVID-19) in Children. J Pediatric Infect Dis Soc. 2020 Nov 10;9(5):596-608. PubMed PMID: 32840614
• DomBourian MG, Annen K, Huey L, Andersen G, Merkel PA, Jung S, Dominguez SR, Knight V. Analysis of COVID-19 convalescent plasma for SARS-CoV-2 IgG using two commercial immunoassays. J Immunol Methods. 2020 Nov;486:112837. PubMed PMID: 32828791
• Gould CV, Messacar K, Dominguez SR, Panella A, Tobolowsky F, Fischer M. Evaluation for Arboviral Infection Among Children Hospitalized in Colorado With Aseptic Meningitis and Encephalitis. Pediatr Infect Dis J. 2020 Nov;39(11):e382-e384. PubMed PMID: 32773665
• Jone PN, Korst A, Karimpour-Fard A, Thomas T, Dominguez SR, Heizer H, Anderson MS, Glode MP, Sucharov CC, Miyamoto SD. Circulating microRNAs differentiate Kawasaki Disease from infectious febrile illnesses in childhood. J Mol Cell Cardiol. 2020 Sep;146:12-18. PubMed PMID: 32634388
• Messacar K, Gaensbauer JT, Birkholz M, Palmer C, Todd JK, Tyler KL, Dominguez SR. Impact of FilmArray meningitis encephalitis panel on HSV testing and empiric acyclovir use in children beyond the neonatal period. Diagn Microbiol Infect Dis. 2020 Aug;97(4):115085. PubMed PMID: 32559588
• Dodson DS, Dominguez SR, MacBrayne CE, Williams MC, Parker SK. Vancomycin-Nonsusceptible Enterococci Mediated by vanC at a Large Children's Hospital: Prevalence, Susceptibility, and Impact on Care of Enterococcal Bacteremia. Open Forum Infect Dis. 2020 May;7(5):ofaa160. PubMed PMID: 32478121
• Hao S, Ling XB, Kanegaye JT, Bainto E, Dominguez SR, Heizer H, Jone PN, Anderson MS, Jaggi P, Baker A, Son MB, Newburger JW, Ashouri N, McElhinney DB, Burns JC, Whitin JC, Cohen HJ, Tremoulet AH. Multicentre validation of a computer-based tool for differentiation of acute Kawasaki disease from clinically similar febrile illnesses. Arch Dis Child. 2020 Aug;105(8):772-777. PubMed PMID: 32139365
• Cotter JM, Thomas J, Birkholz M, Brittan M, Ambroggio L, Dolan S, Pearce K, Todd J, Dominguez SR. Impact of Multiplex Testing on the Identification of Pediatric Clostridiodes Difficile. J Pediatr. 2020 Mar;218:157-165.e3. PubMed PMID: 32089179
• Mayer EF, Maron G, Dallas RH, Ferrolino J, Tang L, Sun Y, Danziger-Isakov L, Paulsen GC, Fisher BT, Vora SB, Englund J, Steinbach WJ, Michaels M, Green M, Yeganeh N, Gibson JE, Dominguez SR, Nicholson MR, Dulek DE, Ardura MI, Rajan S, Gonzalez BE, Beneri C, Herold BC. A multicenter study to define the epidemiology and outcomes of Clostridioides difficile infection in pediatric hematopoietic cell and solid organ transplant recipients. Am J Transplant. 2020 Aug;20(8):2133-2142. PubMed PMID: 32064754
• Tran P, Dowell E, Hamilton S, Dolan SA, Messacar K, Dominguez SR, Todd J. Two Blood Cultures With Age-Appropriate Volume Enhance Suspected Sepsis Decision-Making. Open Forum Infect Dis. 2020 Feb;7(2):ofaa028. PubMed PMID: 32055641
• Meyers L, Dien Bard J, Galvin B, Nawrocki J, Niesters HGM, Stellrecht KA, St George K, Daly JA, Blaschke AJ, Robinson C, Wang H, Cook CV, Hassan F, Dominguez SR, Pretty K, Naccache S, Olin KE, Althouse BM, Jones JD, Ginocchio CC, Poritz MA, Leber A, Selvarangan R. Enterovirus D68 outbreak detection through a syndromic disease epidemiology network. J Clin Virol. 2020 Mar;124:104262. PubMed PMID: 32007841
• Messacar K, Spence-Davizon E, Osborne C, Press C, Schreiner TL, Martin J, Messer R, Maloney J, Burakoff A, Barnes M, Rogers S, Lopez AS, Routh J, Gerber SI, Oberste MS, Nix WA, Abzug MJ, Tyler KL, Herlihy R, Dominguez SR. Clinical characteristics of enterovirus A71 neurological disease during an outbreak in children in Colorado, USA, in 2018: an observational cohort study. Lancet Infect Dis. 2020 Feb;20(2):230-239. PubMed PMID: 31859216
• Nycz BT, Pretty K, Gomez-Trujillo A, Sanchez B, Dominguez SR. Description of Enteropathic Escherichia coli Species in Pediatric Patients at a Quaternary Children's Hospital. J Pediatric Infect Dis Soc. 2020 Nov 10;9(5):573-579. PubMed PMID: 31803928
• Venkatesan S, Myles PR, Bolton KJ, Muthuri SG, Al Khuwaitir T, Anovadiya AP, Azziz-Baumgartner E, Bajjou T, Bassetti M, Beovic B, Bertisch B, Bonmarin I, Booy R, Borja-Aburto VH, Burgmann H, Cao B, Carratala J, Chinbayar T, Cilloniz C, Denholm JT, Dominguez SR, Duarte PAD, Dubnov-Raz G, Fanella S, Gao Z, Gérardin P, Giannella M, Gubbels S, Herberg J, Higuera Iglesias AL, Hoeger PH, Hu XY, Islam QT, Jiménez MF, Keijzers G, Khalili H, Kusznierz G, Kuzman I, Langenegger E, Lankarani KB, Leo YS, Libster RP, Linko R, Madanat F, Maltezos E, Mamun A, Manabe T, Metan G, Mickiene A, Mikic D, Mohn KGI, Oliva ME, Ozkan M, Parekh D, Paul M, Rath BA, Refaey S, Rodríguez AH, Sertogullarindan B, Skret-Magierlo J, Somer A, Talarek E, Tang JW, To K, Tran D, Uyeki TM, Vaudry W, Vidmar T, Zarogoulidis P, Nguyen-Van-Tam JS. Neuraminidase Inhibitors and Hospital Length of Stay: A Meta-analysis of Individual Participant Data to Determine Treatment Effectiveness Among Patients Hospitalized With Nonfatal 2009 Pandemic Influenza A(H1N1) Virus Infection. J Infect Dis. 2020 Jan 14;221(3):356-366. PubMed PMID: 31314899
• Searns JB, Gralla J, Parker SK, Dominguez SR. Potential Clinical Effects of a Novel Rapid Diagnostic Panel for Pediatric Musculoskeletal Infections. J Pediatric Infect Dis Soc. 2020 Jul 13;9(3):382-385. PubMed PMID: 31194251
• Rao S, Martin J, Ahearn MA, Osborne C, Moss A, Dempsey A, Dominguez SR, Weinberg A, Messacar KB. Neurologic Manifestations of Influenza A(H3N2) Infection in Children During the 2016-2017 Season. J Pediatric Infect Dis Soc. 2020 Feb 28;9(1):71-74. PubMed PMID: 30590598
• Rao S, Martin J, Ahearn MA, Osborne C, Moss A, Dempsey A, Dominguez SR, Weinberg A, Messacar KB. Neurologic Manifestations of Influenza A(H3N2) Infection in Children During the 2016-2017 Season. J Pediatric Infect Dis Soc. 2020 Feb 28;9(1):71-74. PubMed PMID: 30590598
• Searns JB, Gralla J, Parker SK, Dominguez SR. Potential Clinical Effects of a Novel Rapid Diagnostic Panel for Pediatric Musculoskeletal Infections. J Pediatric Infect Dis Soc. 2020 Jul 13;9(3):382-385. PubMed PMID: 31194251
• Venkatesan S, Myles PR, Bolton KJ, Muthuri SG, Al Khuwaitir T, Anovadiya AP, Azziz-Baumgartner E, Bajjou T, Bassetti M, Beovic B, Bertisch B, Bonmarin I, Booy R, Borja-Aburto VH, Burgmann H, Cao B, Carratala J, Chinbayar T, Cilloniz C, Denholm JT, Dominguez SR, Duarte PAD, Dubnov-Raz G, Fanella S, Gao Z, Gérardin P, Giannella M, Gubbels S, Herberg J, Higuera Iglesias AL, Hoeger PH, Hu XY, Islam QT, Jiménez MF, Keijzers G, Khalili H, Kusznierz G, Kuzman I, Langenegger E, Lankarani KB, Leo YS, Libster RP, Linko R, Madanat F, Maltezos E, Mamun A, Manabe T, Metan G, Mickiene A, Mikic D, Mohn KGI, Oliva ME, Ozkan M, Parekh D, Paul M, Rath BA, Refaey S, Rodríguez AH, Sertogullarindan B, Skret-Magierlo J, Somer A, Talarek E, Tang JW, To K, Tran D, Uyeki TM, Vaudry W, Vidmar T, Zarogoulidis P, Nguyen-Van-Tam JS. Neuraminidase Inhibitors and Hospital Length of Stay: A Meta-analysis of Individual Participant Data to Determine Treatment Effectiveness Among Patients Hospitalized With Nonfatal 2009 Pandemic Influenza A(H1N1) Virus Infection. J Infect Dis. 2020 Jan 14;221(3):356-366. PubMed PMID: 31314899
• Nycz BT, Pretty K, Gomez-Trujillo A, Sanchez B, Dominguez SR. Description of Enteropathic Escherichia coli Species in Pediatric Patients at a Quaternary Children's Hospital. J Pediatric Infect Dis Soc. 2020 Nov 10;9(5):573-579. PubMed PMID: 31803928
• Messacar K, Spence-Davizon E, Osborne C, Press C, Schreiner TL, Martin J, Messer R, Maloney J, Burakoff A, Barnes M, Rogers S, Lopez AS, Routh J, Gerber SI, Oberste MS, Nix WA, Abzug MJ, Tyler KL, Herlihy R, Dominguez SR. Clinical characteristics of enterovirus A71 neurological disease during an outbreak in children in Colorado, USA, in 2018: an observational cohort study. Lancet Infect Dis. 2020 Feb;20(2):230-239. PubMed PMID: 31859216
• Meyers L, Dien Bard J, Galvin B, Nawrocki J, Niesters HGM, Stellrecht KA, St George K, Daly JA, Blaschke AJ, Robinson C, Wang H, Cook CV, Hassan F, Dominguez SR, Pretty K, Naccache S, Olin KE, Althouse BM, Jones JD, Ginocchio CC, Poritz MA, Leber A, Selvarangan R. Enterovirus D68 outbreak detection through a syndromic disease epidemiology network. J Clin Virol. 2020 Mar;124:104262. PubMed PMID: 32007841
• Tran P, Dowell E, Hamilton S, Dolan SA, Messacar K, Dominguez SR, Todd J. Two Blood Cultures With Age-Appropriate Volume Enhance Suspected Sepsis Decision-Making. Open Forum Infect Dis. 2020 Feb;7(2):ofaa028. PubMed PMID: 32055641
• Mayer EF, Maron G, Dallas RH, Ferrolino J, Tang L, Sun Y, Danziger-Isakov L, Paulsen GC, Fisher BT, Vora SB, Englund J, Steinbach WJ, Michaels M, Green M, Yeganeh N, Gibson JE, Dominguez SR, Nicholson MR, Dulek DE, Ardura MI, Rajan S, Gonzalez BE, Beneri C, Herold BC. A multicenter study to define the epidemiology and outcomes of Clostridioides difficile infection in pediatric hematopoietic cell and solid organ transplant recipients. Am J Transplant. 2020 Aug;20(8):2133-2142. PubMed PMID: 32064754
• Cotter JM, Thomas J, Birkholz M, Brittan M, Ambroggio L, Dolan S, Pearce K, Todd J, Dominguez SR. Impact of Multiplex Testing on the Identification of Pediatric Clostridiodes Difficile. J Pediatr. 2020 Mar;218:157-165.e3. PubMed PMID: 32089179
• Hao S, Ling XB, Kanegaye JT, Bainto E, Dominguez SR, Heizer H, Jone PN, Anderson MS, Jaggi P, Baker A, Son MB, Newburger JW, Ashouri N, McElhinney DB, Burns JC, Whitin JC, Cohen HJ, Tremoulet AH. Multicentre validation of a computer-based tool for differentiation of acute Kawasaki disease from clinically similar febrile illnesses. Arch Dis Child. 2020 Aug;105(8):772-777. PubMed PMID: 32139365
• Dodson DS, Dominguez SR, MacBrayne CE, Williams MC, Parker SK. Vancomycin-Nonsusceptible Enterococci Mediated by vanC at a Large Children's Hospital: Prevalence, Susceptibility, and Impact on Care of Enterococcal Bacteremia. Open Forum Infect Dis. 2020 May;7(5):ofaa160. PubMed PMID: 32478121
• Messacar K, Gaensbauer JT, Birkholz M, Palmer C, Todd JK, Tyler KL, Dominguez SR. Impact of FilmArray meningitis encephalitis panel on HSV testing and empiric acyclovir use in children beyond the neonatal period. Diagn Microbiol Infect Dis. 2020 Aug;97(4):115085. PubMed PMID: 32559588
• Jone PN, Korst A, Karimpour-Fard A, Thomas T, Dominguez SR, Heizer H, Anderson MS, Glode MP, Sucharov CC, Miyamoto SD. Circulating microRNAs differentiate Kawasaki Disease from infectious febrile illnesses in childhood. J Mol Cell Cardiol. 2020 Sep;146:12-18. PubMed PMID: 32634388
• Gould CV, Messacar K, Dominguez SR, Panella A, Tobolowsky F, Fischer M. Evaluation for Arboviral Infection Among Children Hospitalized in Colorado With Aseptic Meningitis and Encephalitis. Pediatr Infect Dis J. 2020 Nov;39(11):e382-e384. PubMed PMID: 32773665
• DomBourian MG, Annen K, Huey L, Andersen G, Merkel PA, Jung S, Dominguez SR, Knight V. Analysis of COVID-19 convalescent plasma for SARS-CoV-2 IgG using two commercial immunoassays. J Immunol Methods. 2020 Nov;486:112837. PubMed PMID: 32828791
• Shane AL, Sato AI, Kao C, Adler-Shohet FC, Vora SB, Auletta JJ, Nachman S, Raabe VN, Inagaki K, Akinboyo IC, Woods C, Alsulami AO, Kainth MK, Santos RP, Espinosa CM, Burns JE, Cunningham CK, Dominguez SR, Martinez BL, Zhu F, Crews J, Kitano T, Saiman L, Kotloff K. A Pediatric Infectious Diseases Perspective of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Novel Coronavirus Disease 2019 (COVID-19) in Children. J Pediatric Infect Dis Soc. 2020 Nov 10;9(5):596-608. PubMed PMID: 32840614
• Williams MC, Dominguez SR, Prinzi A, Lee K, Parker SK. Reliability of mecA in Predicting Phenotypic Susceptibilities of Coagulase-Negative Staphylococci and Staphylococcus aureus . Open Forum Infect Dis. 2020 Dec;7(12):ofaa553. PubMed PMID: 33409329
• Gaensbauer JT, Lamb M, Calvimontes DM, Asturias EJ, Kamidani S, Contreras-Roldan IL, Dominguez SR, Robinson CC, Zacarias A, Berman S, Melgar MA. Identification of Enteropathogens by Multiplex PCR among Rural and Urban Guatemalan Children with Acute Diarrhea. Am J Trop Med Hyg. 2019 Sep;101(3):534-540. PubMed PMID: 31392942
• Venkatesan S, Myles PR, Bolton KJ, Muthuri SG, Al Khuwaitir T, Anovadiya AP, Azziz-Baumgartner E, Bajjou T, Bassetti M, Beovic B, Bertisch B, Bonmarin I, Booy R, Borja-Aburto VH, Burgmann H, Cao B, Carratala J, Chinbayar T, Cilloniz C, Denholm JT, Dominguez SR, Duarte PAD, Dubnov-Raz G, Fanella S, Gao Z, Gérardin P, Giannella M, Gubbels S, Herberg J, Higuera Iglesias AL, Hoeger PH, Hu XY, Islam QT, Jiménez MF, Keijzers G, Khalili H, Kusznierz G, Kuzman I, Langenegger E, Lankarani KB, Leo YS, Libster RP, Linko R, Madanat F, Maltezos E, Mamun A, Manabe T, Metan G, Mickiene A, Mikic D, Mohn KGI, Oliva ME, Ozkan M, Parekh D, Paul M, Rath BA, Refaey S, Rodríguez AH, Sertogullarindan B, Skret-Magierlo J, Somer A, Talarek E, Tang JW, To K, Tran D, Uyeki TM, Vaudry W, Vidmar T, Zarogoulidis P, Nguyen-Van-Tam JS. Neuraminidase Inhibitors and Hospital Length of Stay: A Meta-analysis of Individual Participant Data to Determine Treatment Effectiveness Among Patients Hospitalized With Nonfatal 2009 Pandemic Influenza A(H1N1) Virus Infection. J Infect Dis. 2019 Jul 17. [Epub ahead of print] PubMed PMID: 31314899
• Kirkley MJ, Robinson C, Dominguez SR, Messacar K. Neonatal parechovirus infection mimicking a surgical abdomen. BMJ Case Rep. 2019 Jun 26;12(6). PubMed PMID: 31248894
• Nycz BT, Pretty K, Gomez-Trujillo A, Sanchez B, Dominguez SR. Description of Enteropathic Escherichia coli Species in Pediatric Patients at a Quaternary Children's Hospital. J Pediatric Infect Dis Soc. 2019 Dec 5. [Epub ahead of print] PubMed PMID: 31803928
• Olson CA, Dominguez SR, Miller S, Chiu CY, Messacar K. Gastroenteritis, Hepatitis, Encephalopathy, and Human Herpesvirus 6 Detection in an Immunocompetent Child: Benefits and Risks of Syndromic Multiplex Molecular Panel Testing. J Pediatr. 2019 Sep;212:228-231. PubMed PMID: 31208781
• Wilson MR, Sample HA, Zorn KC, Arevalo S, Yu G, Neuhaus J, Federman S, Stryke D, Briggs B, Langelier C, Berger A, Douglas V, Josephson SA, Chow FC, Fulton BD, DeRisi JL, Gelfand JM, Naccache SN, Bender J, Dien Bard J, Murkey J, Carlson M, Vespa PM, Vijayan T, Allyn PR, Campeau S, Humphries RM, Klausner JD, Ganzon CD, Memar F, Ocampo NA, Zimmermann LL, Cohen SH, Polage CR, DeBiasi RL, Haller B, Dallas R, Maron G, Hayden R, Messacar K, Dominguez SR, Miller S, Chiu CY. Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis. N Engl J Med. 2019 Jun 13;380(24):2327-2340. PubMed PMID: 31189036
• Messacar K, Robinson CC, Dominguez SR. Letter to the editor: economic analysis lacks external validity to support universal syndromic testing for suspected meningitis/encephalitis. Future Microbiol. 2018 Nov;13:1553-1554. PubMed PMID: 30421966
• Messacar K, Sillau S, Hopkins SE, Otten C, Wilson-Murphy M, Wong B, Santoro JD, Treister A, Bains HK, Torres A, Zabrocki L, Glanternik JR, Hurst AL, Martin JA, Schreiner T, Makhani N, DeBiasi RL, Kruer MC, Tremoulet AH, Van Haren K, Desai J, Benson LA, Gorman MP, Abzug MJ, Tyler KL, Dominguez SR. Safety, tolerability, and efficacy of fluoxetine as an antiviral for acute flaccid myelitis. Neurology. 2018 Nov 9. [Epub ahead of print] PubMed PMID: 30413631
• Messacar K, Dominguez SR. Blood PCR testing for enteroviruses in young children. Lancet Infect Dis. 2018 Oct 30. [Epub ahead of print] PubMed PMID: 30389483
• Searns J, Cataldi JR, McCormack K, Simões E, Messacar K, Dominguez SR. A 4-Year-Old Boy With an Unusual Bacterial Meningitis Infection. J Pediatric Infect Dis Soc. 2018 Oct 9. [Epub ahead of print] PubMed PMID: 30299497
• Messacar K, Hamilton SL, Prinzi AM, Mitchell JC, Beil ED, Dowell EB, Dominguez SR. Rapid identification of nonblood sterile site broth cultures using the FilmArray blood culture identification panel. Diagn Microbiol Infect Dis. 2018 Jul 31. [Epub ahead of print] PubMed PMID: 30213466
• Messacar K, Burakoff A, Nix WA, Rogers S, Oberste MS, Gerber SI, Spence-Davizon E, Herlihy R, Dominguez SR. Notes from the Field: Enterovirus A71 Neurologic Disease in Children - Colorado, 2018. MMWR Morb Mortal Wkly Rep. 2018 Sep 14;67(36):1017-1018. PubMed PMID: 30212441
• Dominguez SR, Pretty K, Hengartner R, Robinson CC. Comparison of Herpes Simplex Virus PCR with Culture for Virus Detection in Multisource Surface Swab Specimens from Neonates. J Clin Microbiol. 2018 Oct;56(10). PubMed PMID: 29875197
• Messacar K, Asturias EJ, Hixon AM, Van Leer-Buter C, Niesters HGM, Tyler KL, Abzug MJ, Dominguez SR. Enterovirus D68 and acute flaccid myelitis-evaluating the evidence for causality. Lancet Infect Dis. 2018 Aug;18(8):e239-e247. PubMed PMID: 29482893
• Jone PN, Anderson MS, Mulvahill MJ, Heizer H, Glodé MP, Dominguez SR. Infliximab Plus Intravenous Immunoglobulin (IVIG) Versus IVIG Alone as Initial Therapy in Children With Kawasaki Disease Presenting With Coronary Artery Lesions: Is Dual Therapy More Effective?. Pediatr Infect Dis J. 2018 Oct;37(10):976-980. PubMed PMID: 29461447
• Saporta-Keating SR, Simões EAF, Yu G, Federman S, Mirsky D, Dominguez SR, Chiu CY, Messacar K. A Child With Intermittent Headaches and Eosinophilic Meningitis. J Pediatric Infect Dis Soc. 2018 Feb 9. [Epub ahead of print] PubMed PMID: 29438532
• Nycz BT, Dominguez SR, Friedman D, Hilden JM, Ir D, Robertson CE, Frank DN. Evaluation of bloodstream infections, Clostridium difficile infections, and gut microbiota in pediatric oncology patients. PLoS One. 2018;13(1):e0191232. PubMed PMID: 29329346
• Messacar K, Fischer M, Dominguez SR, Tyler KL, Abzug MJ. Encephalitis in US Children. Infect Dis Clin North Am. 2018 Mar;32(1):145-162. PubMed PMID: 29224854
• Brumbaugh DE, De Zoeten EF, Pyo-Twist A, Fidanza S, Hughes S, Dolan SA, Child J, Dominguez SR. An Intragastric Fecal Microbiota Transplantation Program for Treatment of Recurrent Clostridium difficile in Children is Efficacious, Safe, and Inexpensive. J Pediatr. 2018 Mar;194:123-127.e1. PubMed PMID: 29198534
• Messacar K, Abzug MJ, Dominguez SR. The changing epidemiology of acute flaccid paralysis warrants a paradigm shift in surveillance. J Med Virol. 2018 Jan;90(1):1-2. PubMed PMID: 29023852
• Searns JB, Robinson CC, Wei Q, Yuan J, Hamilton S, Pretty K, Donaldson N, Parker SK, Dominguez SR. Validation of a novel molecular diagnostic panel for pediatric musculoskeletal infections: Integration of the cepheid Xpert MRSA/SA SSTI and laboratory-developed real-time PCR assays for clindamycin resistance genes and Kingella kingae detection. J Microbiol Methods. 2018 Dec 7. [Epub ahead of print] PubMed PMID: 30527965
• Nycz BT, Dominguez SR, Friedman D, Hilden JM, Ir D, Robertson CE, Frank DN. Correction: Evaluation of bloodstream infections, Clostridium difficile infections, and gut microbiota in pediatric oncology patients. PLoS One. 2018;13(5):e0197530. PubMed PMID: 29746574
• Messacar K, Dominguez SR. Blood PCR testing for enteroviruses in young children. Lancet Infect Dis. 2018 Dec;18(12):1299-1301. PubMed PMID: 30389483
• Muthuri SG, Venkatesan S, Myles PR, Leonardi-Bee J, Lim WS, Mamun AA, Anovadiya AP, Araújo WN, Azziz-Baumgartner E, Báez C, Bantar C, Barhoush MM, Bassetti M, Beovic B, Bingisser R, Bonmarin I, Borja-Aburto VH, Cao B, Carratala J, Cuezzo MR, Denholm JT, Dominguez SR, Duarte PA, Dubnov-Raz G, Echavarria M, Fanella S, Fraser J, Gao Z, Gérardin P, Giannella M, Gubbels S, Herberg J, Iglesias AL, Hoeger PH, Hoffmann M, Hu X, Islam QT, Jiménez MF, Kandeel A, Keijzers G, Khalili H, Khandaker G, Knight M, Kusznierz G, Kuzman I, Kwan AM, Amine IL, Langenegger E, Lankarani KB, Leo YS, Linko R, Liu P, Madanat F, Manabe T, Mayo-Montero E, McGeer A, Memish ZA, Metan G, Mikic D, Mohn KG, Moradi A, Nymadawa P, Ozbay B, Ozkan M, Parekh D, Paul M, Poeppl W, Polack FP, Rath BA, Rodríguez AH, Siqueira MM, Skret-Magierlo J, Talarek E, Tang JW, Torres A, Törün SH, Tran D, Uyeki TM, van Zwol A, Vaudry W, Velyvyte D, Vidmar T, Zarogoulidis P, Nguyen-Van-Tam JS. Impact of neuraminidase inhibitors on influenza A(H1N1)pdm09-related pneumonia: an IPD meta-analysis. Influenza Other Respir Viruses. 2015 Nov 25. [Epub ahead of print] PubMed PMID: 26602067
• Dantes R, Epson EE, Dominguez SR, Dolan S, Wang F, Hurst A, Parker SK, Johnston H, West K, Anderson L, Rasheed JK, Moulton-Meissner H, Noble-Wang J, Limbago B, Dowell E, Hilden JM, Guh A, Pollack LA, Gould CV. Investigation of a cluster of Clostridium difficile infections in a pediatric oncology setting. Am J Infect Control. 2015 Oct 22. [Epub ahead of print] PubMed PMID: 26601705
• Midgley CM, Watson JT, Nix WA, Curns AT, Rogers SL, Brown BA, Conover C, Dominguez SR, Feikin DR, Gray S, Hassan F, Hoferka S, Jackson MA, Johnson D, Leshem E, Miller L, Nichols JB, Nyquist AC, Obringer E, Patel A, Patel M, Rha B, Schneider E, Schuster JE, Selvarangan R, Seward JF, Turabelidze G, Oberste MS, Pallansch MA, Gerber SI. Severe respiratory illness associated with a nationwide outbreak of enterovirus D68 in the USA (2014): a descriptive epidemiological investigation. Lancet Respir Med. 2015 Nov;3(11):879-87. PubMed PMID: 26482320
• Phadke D, Patel SS, Dominguez SR, Heizer H, Anderson MS, Glode MP, Jone PN. Tissue Doppler Imaging as a Predictor of Immunoglobulin Resistance in Kawasaki Disease. Pediatr Cardiol. 2015 Dec;36(8):1618-23. PubMed PMID: 25991572
• Greninger AL, Naccache SN, Messacar K, Clayton A, Yu G, Somasekar S, Federman S, Stryke D, Anderson C, Yagi S, Messenger S, Wadford D, Xia D, Watt JP, Van Haren K, Dominguez SR, Glaser C, Aldrovandi G, Chiu CY. A novel outbreak enterovirus D68 strain associated with acute flaccid myelitis cases in the USA (2012-14): a retrospective cohort study. Lancet Infect Dis. 2015 Jun;15(6):671-82. PubMed PMID: 25837569
• Maloney JA, Mirsky DM, Messacar K, Dominguez SR, Schreiner T, Stence NV. MRI findings in children with acute flaccid paralysis and cranial nerve dysfunction occurring during the 2014 enterovirus D68 outbreak. AJNR Am J Neuroradiol. 2015 Feb;36(2):245-50. PubMed PMID: 25414005
• Messacar K, Robinson CC, Bagdure D, Curtis DJ, Glodé MP, Dominguez SR. Rhino/enteroviruses in hospitalized children: A comparison to influenza viruses. J Clin Virol. 2013 Jan;56(1):41-5. PubMed PMID: 23078869
• Dominguez SR, Anderson MS. Advances in the treatment of Kawasaki disease. Curr Opin Pediatr. 2012 Dec 31. [Epub ahead of print] PubMed PMID: 23283289
• Eladawy M, Dominguez SR, Anderson MS, Glodé MP. Kawasaki Disease Presenting To the Pediatric Gastroenterologist: A Diagnostic Challenge. J Pediatr Gastroenterol Nutr. 2012 Oct 18. [Epub ahead of print] PubMed PMID: 23085893
• Dominguez SR, Sims GE, Wentworth DE, Halpin RA, Robinson CC, Town CD, Holmes KV. Genomic analysis of 16 Colorado human NL63 coronaviruses identifies a new genotype, high sequence diversity in the N-terminal domain of the spike gene and evidence of recombination. J Gen Virol. 2012 Nov;93(Pt 11):2387-98. PubMed PMID: 22837419
• Dominguez SR, Anderson MS, El-Adawy M, Glodé MP. Preventing coronary artery abnormalities: a need for earlier diagnosis and treatment of kawasaki disease. Pediatr Infect Dis J. 2012 Dec;31(12):1217-20. PubMed PMID: 22760536

Professional Memberships

• Christian Medical and Dental Association, Member
• American Academy of Pediatrics, Member
• Christian Community Health, Fellow
• Pediatric Infectious Disease Society, Member
• Infectious Disease Society of America, Member
• American Society of Microbiology, Member