Stuart Lind, MD

Publications

• Lind SE. “The bleeding time” in Platelets, 2nd edition, Michelson AD (editor) Academic Press, Amsterdam, 2006.
• 59. Prodan CI, Bottomley SS, Holland NR, Lind SE. Relapsing hypocupremic myelopathy requiring high dose oral copper replacement. Journal of Neurology, Neurosurgery & Psychiatry.77:1092-1093, 2006
• 60. Ding WQ, Liu B, Vaught JL, Palmiter RD, Lind SE. Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells. Molecular Cancer Therapeutics.5:1864-1872, 2006.
• 61. Prodan CI, Bottomley SS, Vincent AS, Cowan LD, Holland NR, Lind SE. Hypocupremia associated with prior vitamin B12 deficiency" Amer J. Hematology. In press.
• Prodan CI, Bottomley SS, Vincent AS, Cowan LD, Holland NR, Lind SE. Hypocupremia associated with prior vitamin B12 deficiency" Amer. J. Hematology. 82:288-290, 2007.
• Ding WQ, Lind SE. Phospholipid hydroperoxide glutathione peroxidase plays a role in protecting cancer cells from docosahexaenoic acid-induced cytotoxicity. Molecular Cancer Therapeutics. 6:1467-1474, 2007.
• Ding WQ, Yu H, Lind SE. Zinc-binding compounds induce cancer cell death via distinct modes of action. Cancer Letters 271: 251-259, 2008
• Yu H, Zhou Y, Lind SE, Ding WQ. Clioquinol targets zinc to lysosomes in human cancer cells. Biochem. J. 417:133-139, 2009.
• Alimova IN, Liu B, Fan Z, Edgerton SM, Dillon, Lind SE, Thor AD. Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro. Cell Cycle – in press
• Yu H, Zhou Y, Lind SE, Ding WQ. Clioquinol targets zinc to lysosomes in human cancer cells. Biochem. J. 417:133-139, 2009.
• Alimova IN, Liu B, Fan Z, Edgerton SM, Dillon, Lind SE, Thor AD. Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro. Cell Cycle 8:909-915, 2009.
• Prodan CI, Bottomley SS, Vincent AS, Cowan LD, Greenwood-Van Meerveld B, Holland NR, Lind SE. Copper deficiency after gastric surgery: a reason for caution. Am J Med Sci 337:256-258, 2009.
• Bolin L, Fan, Edgerton SM, Deng XS, Alimova IN, Lind SE, Thor AD. Metformin induces unique biological and molecular responses in triple negative breast cancer cells. Cell Cycle 8:2031-40, 2009.
• Lind SE, Park JS, Drexler JW. Pyrithione and 8-hydroxyquinolines transport lead across erythrocyte membranes. Translational Research 154:153-159, 2009.
• Ding WQ, Lind SE. Metal ionophores - an emerging class of anticancer drugs. IUBMB Life 61:1013-1018, 2009.
• Zhang X, Yu, H, Lou JR, Zheng J, Zhu H, Popescu NI, Lupu F, Lind SE, Ding WQ. MicroRNA-19 (miR-19) regulates tissue factor expression in breast cancer cells. J Biol Chem 286:1429-1435, 2011.
• Liu B, Fan Z, Edgerton SM, Yang X, Lind SE, Thor AD. Potent anti-proliferative effects of metformin on trastuzumab-resistant breast cancer cells via inhibition of erbB2/IGF-1 receptor interactions. Cell Cycle. 10:2959-2966, 2011.
• Jiang H, Taggart JE, Zhang X, Benbrook DM, Lind SE, Ding WQ. Nitroxoline (8-hydroxy-5-nitroquinoline) is more a potent anti-cancer agent than clioquinol (5-chloro-7-iodo-8-quinoline). Cancer Lett. 312:11-7, 2011.
• Deng X-S, Wang S, Deng A, Liu B, Edgerton SM, Lind SE, Wahdan-Alaswad R, Thor AD. Metformin targets Stat3 to inhibit cell growth and induce apoptosis in triple negative breast cancers. Cell Cycle 11:367-376,2012.
• Deng X-S, Wang S, Deng A, Liu B, Edgerton SM, Lind SE, Wahdan-Alaswad R, Thor AD. Metformin targets Stat3 to inhibit cell growth and induce apoptosis in triple negative breast cancers. Cell Cycle Cell Cycle. 11:367-376, 2012.
• Zheng J, Payne K, Taggart JE, Jiang H, Lind SE, Ding WQ. Trolox enhances curcumin's cytotoxicity through induction of oxidative stress. Cell Physiol Biochem. 29:353-360, 2012.
• Zhou J, Zhang S, Xue J, Avery J, Wu J, Lind SE, Ding WQ. Activation of peroxisome proliferator-activated receptor a (PPARa) suppresses hypoxia-inducible factor-1a (HIF-1a) signaling in cancer cells. J Biol Chem. 287:35161-35169, 2012.
• Wang S, Avery JE, Hannafon BN, Lind SE, Ding WQ. Zinc protoporphyrin suppresses cancer cell viability through a heme oxygenase-1-independent mechanism: the involvement of the Wnt/ß-catenin signaling pathway. Biochem Pharmacol. 2013 Jun 1;85(11):1611-8. PubMed PMID: 23523860
• Lind SE, Boyle ME, Fisher S, Ishimoto J, Trujillo TC, Kiser TH. Comparison of the aPTT with alternative tests for monitoring direct thrombin inhibitors in patient samples. Am J Clin Pathol. 2014 May;141(5):665-74. PubMed PMID: 24713737
• Wang S, Hannafon BN, Wolf RF, Zhou J, Avery JE, Wu J, Lind SE, Ding WQ. Characterization of docosahexaenoic acid (DHA)-induced heme oxygenase-1 (HO-1) expression in human cancer cells: the importance of enhanced BTB and CNC homology 1 (Bach1) degradation. J Nutr Biochem. 2014 May;25(5):515-25. PubMed PMID: 24613086
• Wang S, Hannafon BN, Lind SE, Ding WQ. Zinc Protoporphyrin Suppresses ß-Catenin Protein Expression in Human Cancer Cells: The Potential Involvement of Lysosome-Mediated Degradation. PLoS One. 2015;10(5):e0127413. PubMed PMID: 26000787
• Beyer J, Trujillo T, Fisher S, Ko A, Lind SE, Kiser TH. Evaluation of a Heparin-Calibrated Antifactor Xa Assay for Measuring the Anticoagulant Effect of Oral Direct Xa Inhibitors. Clin Appl Thromb Hemost. 2016 Jul;22(5):423-8. PubMed PMID: 26842561
• Vanderbilt CM, McFarland C, Lind SE. Evaluation of a Reflex Testing Algorithm for Suspected Heparin-Induced Thrombocytopenia. Am J Clin Pathol. 2017 Nov 2;148(5):390-397. PubMed PMID: 29059268
• McFarland CP, Lind SE. Thrombin Generation Biomarkers Decline With Parenteral Anticoagulation-An Overlooked Means of Anticoagulation Monitoring?. Clin Appl Thromb Hemost. 2018 Jul;24(5):708-717. PubMed PMID: 29439639
• Beyer JT, Lind SE, Fisher S, Trujillo TC, Wempe MF, Kiser TH. Evaluation of intravenous direct thrombin inhibitor monitoring tests: Correlation with plasma concentrations and clinical outcomes in hospitalized patients. J Thromb Thrombolysis. 2019 Sep 26. [Epub ahead of print] PubMed PMID: 31559512
• McFarland CP, Lind SE. Thrombin Generation Biomarkers Decline With Parenteral Anticoagulation-An Overlooked Means of Anticoagulation Monitoring?. Clin Appl Thromb Hemost. 2018 Jul;24(5):708-717. PubMed PMID: 29439639
• Beyer JT, Lind SE, Fisher S, Trujillo TC, Wempe MF, Kiser TH. Evaluation of intravenous direct thrombin inhibitor monitoring tests: Correlation with plasma concentrations and clinical outcomes in hospitalized patients. J Thromb Thrombolysis. 2020 Feb;49(2):259-267. PubMed PMID: 31559512
• Lind SE. Phosphatidylserine is an overlooked mediator of COVID-19 thromboinflammation. Heliyon. 2021 Jan;7(1):e06033. PubMed PMID: 33495740
• George G, Friedman KD, Curtis BR, Lind SE. Successful treatment of thrombotic thrombocytopenia with cerebral sinus venous thrombosis following Ad26.COV2.S vaccination. Am J Hematol. 2021 Aug 1;96(8):E301-E303. PubMed PMID: 33989437

Practice Locations

• University of Colorado Hospital

• University of Colorado Cancer Center

Specialty Information

• Internal Medicine, Board Certification (1979)
• Medical Oncology, Board Certification (1981)
• Hematology, Board Certification (1982, 2015)
• Blood Banking / Transfusion Medicine, Board Certification (2007)

• Blood / Lymphatic System
• Blood / Lymphatic System - Blood Disorders
• Cancers
• Cancers - Leukemia (Adult Chronic)
• Cancers - Lymphoma
• Cancers - Myeloma
• Blood / Lymphatic System - Bleeding Disorders
• Blood / Lymphatic System - Clotting Disorders