Todd Wine, MD

Research Interests

My research interests are resource utilization in pediatric otolaryngology, pediatric dysphagia, aerodigestive disorders, Otitis media, pediatric OSA, assessing quality through decision management.

Publications

• Minor J, Wine TM. Mummified leiomyoma of the midline anterior neck. Accepted for publication June 2010. ENT Journal.
• Bowles D, Reddy K, Wine T, Raben D, Chen C, Jimeno A. Locoregional recurrence of an HPV-positive squamous cell carcinoma of the head and neck. Cancer, 2011.
• Hoyte FL, Patel OP, Wine T, Katial RK. Progressive Dyspnea and Supraglottic Stenosis: A Rare Case of Cicatricial Pemphigoid. Poster Presentation. Aspen Allergy Conference, July 27-31.
• Wine TM, Dedhia K, Chi DH. Congenital Nasal Pyriform Aperture Stenosis: Is There a Role for Nasal Dilation?. JAMA Otolaryngol Head Neck Surg. 2014 Mar 6. [Epub ahead of print] PubMed PMID: 24604163
• Wine TM, Simons JP, Mehta DK. Comparison of 2 techniques of tracheocutaneous fistula closure: analysis of outcomes and health care use. JAMA Otolaryngol Head Neck Surg. 2014 Mar 1;140(3):237-42. PubMed PMID: 24481224
• Kent DT, Kitsko DJ, Wine T, Chi DH. Frequency-specific hearing outcomes in pediatric type I tympanoplasty. JAMA Otolaryngol Head Neck Surg. 2014 Feb;140(2):106-11. PubMed PMID: 24357104
• Minor J, Rizeq M, Wine T. Mummified leiomyoma of the midline anterior neck: Case report and literature review. Ear Nose Throat J. 2013 Aug;92(8):E9. PubMed PMID: 23975502
• Wine TM, Duvvuri U, Maurer SH, Mehta DK. Pediatric transoral robotic surgery for oropharyngeal malignancy: a case report. Int J Pediatr Otorhinolaryngol. 2013 Jul;77(7):1222-6. PubMed PMID: 23680523
• Wine TM, Colman KL, Mehta DK, Maguire RC, Morell VO, Simons JP. Aortopexy for innominate artery tracheal compression in children. Otolaryngol Head Neck Surg. 2013 Jul;149(1):151-5. PubMed PMID: 23528271
• Wine TM, Dedhia K, Chi DH. Congenital nasal pyriform aperture stenosis: is there a role for nasal dilation?. JAMA Otolaryngol Head Neck Surg. 2014 Apr;140(4):352-6. PubMed PMID: 24604163
• Wine TM, Simons JP, Mehta DK. Comparison of 2 techniques of tracheocutaneous fistula closure: analysis of outcomes and health care use. JAMA Otolaryngol Head Neck Surg. 2014 Mar;140(3):237-42. PubMed PMID: 24481224
• Kent DT, Kitsko DJ, Wine T, Chi DH. Frequency-specific hearing outcomes in pediatric type I tympanoplasty. JAMA Otolaryngol Head Neck Surg. 2014 Feb;140(2):106-11. PubMed PMID: 24357104
• Kopelovich JC, Wine TM, Rutter MJ, Mitchell MB, Prager JD. Secondary Reverse Slide Tracheoplasty for Airway Rescue. Ann Thorac Surg. 2016 Mar;101(3):1205-7. PubMed PMID: 26897214
• Wine T, Yellon R. Lesions of the Oral Cavity. Ballenger's Otorhinolaryngology, August 2016
• Choanal Atresia and Pyriform Aperture Stenosis. Decision Making in Otolaryngology, Ed. Alper.
• Santos-Cortez RLP, Chiong CM, Frank DN, Ryan AF, Giese APJ, Bootpetch Roberts T, Daly KA, Steritz MJ, Szeremeta W, Pedro M, Pine H, Yarza TKL, Scholes MA, Llanes EGDV, Yousaf S, Friedman N, Tantoco MLC, Wine TM, Labra PJ, Benoit J, Ruiz AG, de la Cruz RAR, Greenlee C, Yousaf A, Cardwell J, Nonato RMA, Ray D, Ong KMC, So E, Robertson CE, Dinwiddie J, Lagrana-Villagracia SM, Gubbels SP, Shaikh RS, Cass SP, Einarsdottir E, Lee NR, Schwartz DA, Gloria-Cruz TLI, Bamshad MJ, Yang IV, Kere J, Abes GT, Prager JD, Riazuddin S, Chan AL, Yoon PJ, Nickerson DA, Cutiongco-de la Paz EM, Streubel SO, Reyes-Quintos MRT, Jenkins HA, Mattila P, Chan KH, Mohlke KL, Leal SM, Hafrén L, Chonmaitree T, Sale MM, Ahmed ZM. FUT2 Variants Confer Susceptibility to Familial Otitis Media. Am J Hum Genet. 2018 Nov 1;103(5):679-690. PubMed PMID: 30401457
• DeBoer EM, Kinder S, Duggar A, Prager JD, Soden J, Deterding RR, Ruiz AG, Jensen EL, Weinman J, Wine T, Fortunato JE, Friedlander JA. Evaluating the yield of gastrointestinal testing in pediatric patients in aerodigestive clinic. Pediatr Pulmonol. 2018 Nov;53(11):1517-1524. PubMed PMID: 30288952
• Masaracchia MM, Polaner DM, Prager JD, DeBoer EM, Dewberry LC, Somme S, Wine T, Janosy NR. Pediatric tracheomalacia and the perioperative anesthetic management of thoracoscopic posterior tracheopexy. Paediatr Anaesth. 2018 Sep;28(9):768-773. PubMed PMID: 29962064
• Wagenaar AE, Mirsky DM, Stence NV, Wine TM, Chan KH. Infection of the spheno-occipital synchondrosis: A morbid complication following adenoidectomy. Int J Pediatr Otorhinolaryngol. 2018 Aug;111:59-62. PubMed PMID: 29958615
• Goldstein NA, Friedman NR, Nardone HC, Aljasser A, Tobey ABJ, Don D, Baroody FM, Lam DJ, Goudy S, Ishman SL, Arganbright JM, Baldassari C, Schreinemakers JBS, Wine TM, Ruszkay NJ, Alammar A, Shaffer AD, Koempel JA, Weedon J. The generalizability of the clinical assessment score-15 for pediatric sleep-disordered breathing. Laryngoscope. 2019 Nov 29. [Epub ahead of print] PubMed PMID: 31782808
• Wisniewski BL, Jensen EL, Prager JD, Wine TM, Baker CD. Pediatric tracheocutaneous fistula closure following tracheostomy decannulation. Int J Pediatr Otorhinolaryngol. 2019 Oct;125:122-127. PubMed PMID: 31299421
• Dewberry L, Wine T, Prager J, Masaracchia M, Janosy N, Polaner D, DeBoer E, Somme S. Thoracoscopic Posterior Tracheopexy Is a Feasible and Effective Treatment for Tracheomalacia. J Laparoendosc Adv Surg Tech A. 2019 Oct;29(10):1228-1231. PubMed PMID: 31219396
• Larson ED, Magno JPM, Steritz MJ, Llanes EGDV, Cardwell J, Pedro M, Roberts TB, Einarsdottir E, Rosanes RAQ, Greenlee C, Santos RAP, Yousaf A, Streubel SO, Santos ATR, Ruiz AG, Lagrana-Villagracia SM, Ray D, Yarza TKL, Scholes MA, Anderson CB, Acharya A, Gubbels SP, Bamshad MJ, Cass SP, Lee NR, Shaikh RS, Nickerson DA, Mohlke KL, Prager JD, Cruz TLG, Yoon PJ, Abes GT, Schwartz DA, Chan AL, Wine TM, Cutiongco-de la Paz EM, Friedman N, Kechris K, Kere J, Leal SM, Yang IV, Patel JA, Tantoco MLC, Riazuddin S, Chan KH, Mattila PS, Reyes-Quintos MRT, Ahmed ZM, Jenkins HA, Chonmaitree T, Hafrén L, Chiong CM, Santos-Cortez RLP. A2ML1 and otitis media: novel variants, differential expression, and relevant pathways. Hum Mutat. 2019 Aug;40(8):1156-1171. PubMed PMID: 31009165
• Ruiz AG, Bhatt JM, DeBoer EM, Friedlander J, Janosy N, Peterson MB, Wine T, Deterding R, Prager JD. Demonstrating the benefits of a multidisciplinary aerodigestive program. Laryngoscope. 2019 Mar 27. [Epub ahead of print] PubMed PMID: 30919460
• Poore TS, Weinman JP, Handley E, Wine T, Helland S, Corbett B, Antoniolli N, Somme S, Friedlander J, Prager JD, DeBoer EM. Vascular and pulmonary comorbidities in children with congenital EA/TEF. Pediatr Pulmonol. 2020 Dec 10. [Epub ahead of print] PubMed PMID: 33300304
• Doody J, Alkhateeb A, Balakrishnan K, Bedwell J, Carter J, Choi SS, Cheng AT, Daniel SJ, Dahl J, De Alarcon A, Fayoux P, Hart CK, Hartnick C, Jonas N, Kuo M, Mills N, Muntz H, Nicollas R, Pransky S, Nuss R, Propst EJ, Rahbar R, Rossi ME, Rutter MJ, Sandu K, Sidell DR, Sittel C, Smith RJH, Soma M, Spratley J, Thierry B, Thompson D, Watters K, Wine T, Wyatt M, Zalzal G, Zdanski CJ, Zur KB, Russell J. International Pediatric Otolaryngology Group (IPOG) consensus recommendations: Management of suprastomal collapse in the pediatric population. Int J Pediatr Otorhinolaryngol. 2020 Dec;139:110427. PubMed PMID: 33120101
• Bootpetch TC, Hafrén L, Elling CL, Baschal EE, Manichaikul AW, Pine HS, Szeremeta W, Scholes MA, Cass SP, Larson ED, Chan KH, Ishaq R, Prager JD, Shaikh RS, Gubbels SP, Yousaf A, Wine TM, Bamshad MJ, Yoon PJ, Jenkins HA, Nickerson DA, Streubel SO, Friedman NR, Frank DN, Einarsdottir E, Kere J, Riazuddin S, Daly KA, Leal SM, Ryan AF, Mattila PS, Ahmed ZM, Sale MM, Chonmaitree T, Santos-Cortez RLP. Multi-omic studies on missense PLG variants in families with otitis media. Sci Rep. 2020 Sep 14;10(1):15035. PubMed PMID: 32929111
• Tashjian M, Ruiz A, Dinwiddie J, Greenlee C, Wine T. Cost of closure: Comparing success and spending of fat graft myringoplasties with and without hyaluronic acid. Int J Pediatr Otorhinolaryngol. 2020 Aug;135:110104. PubMed PMID: 32502911
• Francom CR, Javia LR, Wolter NE, Lee GS, Wine T, Morrissey T, Papsin BC, Peyton JM, Matava CT, Volk MS, Prager JD, Propst EJ. Pediatric laryngoscopy and bronchoscopy during the COVID-19 pandemic: A four-center collaborative protocol to improve safety with perioperative management strategies and creation of a surgical tent with disposable drapes. Int J Pediatr Otorhinolaryngol. 2020 Jul;134:110059. PubMed PMID: 32339971
• Heslop G, Sowa L, Helland S, Corbett B, Wine TM, Somme S, Prager JD. The risks of polytetrafluoroethylene pledget use in tracheopexy. Int J Pediatr Otorhinolaryngol. 2021 Oct;149:110859. PubMed PMID: 34340005
• Hirsch SD, Elling CL, Bootpetch TC, Scholes MA, Hafrén L, Streubel SO, Pine HS, Wine TM, Szeremeta W, Prager JD, Einarsdottir E, Yousaf A, Baschal EE, Rehman S, Bamshad MJ, Nickerson DA, Riazuddin S, Leal SM, Ahmed ZM, Yoon PJ, Kere J, Chan KH, Mattila PS, Friedman NR, Chonmaitree T, Frank DN, Ryan AF, Santos-Cortez RLP. The role of CDHR3 in susceptibility to otitis media. J Mol Med (Berl). 2021 Nov;99(11):1571-1583. PubMed PMID: 34322716
• Goldstein NA, Friedman NR, Nardone HC, Aljasser A, Tobey ABJ, Don D, Baroody FM, Lam DJ, Goudy S, Ishman SL, Arganbright JM, Baldassari C, Schreinemakers JBS, Wine TM, Ruszkay NJ, Alammar A, Shaffer AD, Koempel JA, Weedon J. The Generalizability of the Clinical Assessment Score-15 for Pediatric Sleep-Disordered Breathing. Laryngoscope. 2020 Sep;130(9):2256-2262. PubMed PMID: 31782808
• Vielkind M, Wolter-Warmerdam K, Jackson A, Maybee J, Brown M, Friedlander J, Friedman N, Hickey F, Prager J, Wine T, DeBoer E. Airway obstruction and inflammation on combined bronchoscopy in children with Down syndrome. Pediatr Pulmonol. 2021 Sep;56(9):2932-2939. PubMed PMID: 34245494
• Wine TM, Prager JD, Mirsky DM. Congenital Nasal Pyriform Aperture Stenosis: Evidence of Premature Fusion of the Midline Palatal Suture. AJNR Am J Neuroradiol. 2021 Jun;42(6):1163-1166. PubMed PMID: 33766830
• Ruiz AG, Bhatt JM, DeBoer EM, Friedlander J, Janosy N, Peterson MB, Wine T, Deterding R, Prager JD. Demonstrating the benefits of a multidisciplinary aerodigestive program. Laryngoscope. 2020 Feb;130(2):521-525. PubMed PMID: 30919460
• Poore TS, Weinman JP, Handley E, Wine T, Helland S, Corbett B, Antoniolli N, Somme S, Friedlander J, Prager JD, DeBoer EM. Vascular and pulmonary comorbidities in children with congenital EA/TEF. Pediatr Pulmonol. 2021 Feb;56(2):571-577. PubMed PMID: 33300304
• Doody J, Alkhateeb A, Balakrishnan K, Bedwell J, Carter J, Choi SS, Cheng AT, Daniel SJ, Dahl J, De Alarcon A, Fayoux P, Hart CK, Hartnick C, Jonas N, Kuo M, Mills N, Muntz H, Nicollas R, Pransky S, Nuss R, Propst EJ, Rahbar R, Rossi ME, Rutter MJ, Sandu K, Sidell DR, Sittel C, Smith RJH, Soma M, Spratley J, Thierry B, Thompson D, Watters K, Wine T, Wyatt M, Zalzal G, Zdanski CJ, Zur KB, Russell J. International Pediatric Otolaryngology Group (IPOG) consensus recommendations: Management of suprastomal collapse in the pediatric population. Int J Pediatr Otorhinolaryngol. 2020 Dec;139:110427. PubMed PMID: 33120101
• Bootpetch TC, Hafrén L, Elling CL, Baschal EE, Manichaikul AW, Pine HS, Szeremeta W, Scholes MA, Cass SP, Larson ED, Chan KH, Ishaq R, Prager JD, Shaikh RS, Gubbels SP, Yousaf A, Wine TM, Bamshad MJ, Yoon PJ, Jenkins HA, Nickerson DA, Streubel SO, Friedman NR, Frank DN, Einarsdottir E, Kere J, Riazuddin S, Daly KA, Leal SM, Ryan AF, Mattila PS, Ahmed ZM, Sale MM, Chonmaitree T, Santos-Cortez RLP. Multi-omic studies on missense PLG variants in families with otitis media. Sci Rep. 2020 Sep 14;10(1):15035. PubMed PMID: 32929111
• Tashjian M, Ruiz A, Dinwiddie J, Greenlee C, Wine T. Cost of closure: Comparing success and spending of fat graft myringoplasties with and without hyaluronic acid. Int J Pediatr Otorhinolaryngol. 2020 Aug;135:110104. PubMed PMID: 32502911
• Francom CR, Javia LR, Wolter NE, Lee GS, Wine T, Morrissey T, Papsin BC, Peyton JM, Matava CT, Volk MS, Prager JD, Propst EJ. Pediatric laryngoscopy and bronchoscopy during the COVID-19 pandemic: A four-center collaborative protocol to improve safety with perioperative management strategies and creation of a surgical tent with disposable drapes. Int J Pediatr Otorhinolaryngol. 2020 Jul;134:110059. PubMed PMID: 32339971
• Goldstein NA, Friedman NR, Nardone HC, Aljasser A, Tobey ABJ, Don D, Baroody FM, Lam DJ, Goudy S, Ishman SL, Arganbright JM, Baldassari C, Schreinemakers JBS, Wine TM, Ruszkay NJ, Alammar A, Shaffer AD, Koempel JA, Weedon J. The Generalizability of the Clinical Assessment Score-15 for Pediatric Sleep-Disordered Breathing. Laryngoscope. 2020 Sep;130(9):2256-2262. PubMed PMID: 31782808
• Ruiz AG, Bhatt JM, DeBoer EM, Friedlander J, Janosy N, Peterson MB, Wine T, Deterding R, Prager JD. Demonstrating the benefits of a multidisciplinary aerodigestive program. Laryngoscope. 2020 Feb;130(2):521-525. PubMed PMID: 30919460
• 1. Gropler MC, Wine T, Prager JD. Treatment Options in Airway Obstruction in Congenital heart Disease: Stents and Splints. Curr Treat Options Peds 7, 129-137 (2021). https://doi.org/10.1007/s40746-021-00223-w.
• Enzer KG, Wine TM, Gien J, Somme S, Prager JD, Baker CD. Posterior tracheopexy for preterm infants with severe bronchopulmonary dysplasia and severe tracheobronchomalacia: A case series. Pediatr Pulmonol. 2022 Sep;57(9):2279-2281. PubMed PMID: 35666077
• Elling CL, Scholes MA, Streubel SO, Larson ED, Wine TM, Bootpetch TC, Yoon PJ, Kofonow JM, Gubbels SP, Cass SP, Robertson CE, Jenkins HA, Prager JD, Frank DN, Chan KH, Friedman NR, Ryan AF, Santos-Cortez RLP. The FUT2 Variant c.461G>A (p.Trp154*) Is Associated With Differentially Expressed Genes and Nasopharyngeal Microbiota Shifts in Patients With Otitis Media. Front Cell Infect Microbiol. 2021;11:798246. PubMed PMID: 35096646
• Heslop G, Sowa L, Helland S, Corbett B, Wine TM, Somme S, Prager JD. The risks of polytetrafluoroethylene pledget use in tracheopexy. Int J Pediatr Otorhinolaryngol. 2021 Oct;149:110859. PubMed PMID: 34340005
• Hirsch SD, Elling CL, Bootpetch TC, Scholes MA, Hafrén L, Streubel SO, Pine HS, Wine TM, Szeremeta W, Prager JD, Einarsdottir E, Yousaf A, Baschal EE, Rehman S, Bamshad MJ, Nickerson DA, Riazuddin S, Leal SM, Ahmed ZM, Yoon PJ, Kere J, Chan KH, Mattila PS, Friedman NR, Chonmaitree T, Frank DN, Ryan AF, Santos-Cortez RLP. The role of CDHR3 in susceptibility to otitis media. J Mol Med (Berl). 2021 Nov;99(11):1571-1583. PubMed PMID: 34322716
• Vielkind M, Wolter-Warmerdam K, Jackson A, Maybee J, Brown M, Friedlander J, Friedman N, Hickey F, Prager J, Wine T, DeBoer E. Airway obstruction and inflammation on combined bronchoscopy in children with Down syndrome. Pediatr Pulmonol. 2021 Sep;56(9):2932-2939. PubMed PMID: 34245494
• Wine TM, Prager JD, Mirsky DM. Congenital Nasal Pyriform Aperture Stenosis: Evidence of Premature Fusion of the Midline Palatal Suture. AJNR Am J Neuroradiol. 2021 Jun;42(6):1163-1166. PubMed PMID: 33766830
• Poore TS, Weinman JP, Handley E, Wine T, Helland S, Corbett B, Antoniolli N, Somme S, Friedlander J, Prager JD, DeBoer EM. Vascular and pulmonary comorbidities in children with congenital EA/TEF. Pediatr Pulmonol. 2021 Feb;56(2):571-577. PubMed PMID: 33300304
• Sowa LE, Stillwell PC, Houin PR, Nguyen N, Prager JD, Wine T, Teynor NJ, Meier M, Hanson RB, Francom C, Gitomer SA. Prophylactic inhaled corticosteroids for the management of recurrent croup. Int J Pediatr Otorhinolaryngol. 2023 Jul;170:111600. PubMed PMID: 37201337
• Janosy NR, DeBoer EM, Prager JD, Vogeli J, Wine T, Beacham AO. Social support moderates the relationship between burnout and job satisfaction in aerodigestive team members. Int J Pediatr Otorhinolaryngol. 2023 Jul;170:111602. PubMed PMID: 37224738
• Lee AJ, Prager JD, Mandler TN, Chatterjee D, Wine TM, Janosy NR. Anesthesia for laryngotracheal reconstruction in children: A narrative review. Paediatr Anaesth. 2023 Nov;33(11):883-893. PubMed PMID: 37408495
• Elling CL, Goff SH, Hirsch SD, Tholen K, Kofonow JM, Curtis D, Robertson CE, Prager JD, Yoon PJ, Wine TM, Chan KH, Scholes MA, Friedman NR, Frank DN, Herrmann BW, Santos-Cortez RLP. Otitis Media in Children with Down Syndrome Is Associated with Shifts in the Nasopharyngeal and Middle Ear Microbiotas. Genet Test Mol Biomarkers. 2023 Jul;27(7):221-228. PubMed PMID: 37522794
• Dedhia K, Maltenfort M, Briddell J, Horn D, Li C, Pattisapu P, Preciado D, Pritchett CV, Wine T, Forrest CB. Temporal Trends in and Patient Characteristics Associated with Surgery for Otitis Media. Laryngoscope. 2024 Dec 5. [Epub ahead of print] PubMed PMID: 39633242
• Santos-Cortez RLP, Gomez HZ, Elling CL, Mayher L, Diala OR, Gardner C, Willford K, Zamora VC, Agyepong A, Lee NK, Green KK, Darr OA, Wine TM, Francom CR, Larson ED, Gitomer SA, Schell AE, Frank DN, Friedman NR, Herrmann BW. APOBR Is Downregulated in EBV Tonsils of Children with Obstructive Sleep-Disordered Breathing. Genes (Basel). 2024 Oct 14;15(10). PubMed PMID: 39457448
• Dedhia K, Maltenfort M, Elden L, Horn D, Magnusen B, Pattisapu P, Pritchett CV, Wine T, Utidjian L, Forrest CB. Multi-institutional Assessment of Otitis Media Epidemiology Using Real-world Data. Int J Pediatr Otorhinolaryngol. 2024 Apr;179:111921. PubMed PMID: 38582054
• Elling CL, Goff SH, Hirsch SD, Tholen K, Kofonow JM, Curtis D, Robertson CE, Prager JD, Yoon PJ, Wine TM, Chan KH, Scholes MA, Friedman NR, Frank DN, Herrmann BW, Santos-Cortez RLP. Otitis Media in Children with Down Syndrome Is Associated with Shifts in the Nasopharyngeal and Middle Ear Microbiotas. Genet Test Mol Biomarkers. 2023 Jul;27(7):221-228. PubMed PMID: 37522794
• Lee AJ, Prager JD, Mandler TN, Chatterjee D, Wine TM, Janosy NR. Anesthesia for laryngotracheal reconstruction in children: A narrative review. Paediatr Anaesth. 2023 Nov;33(11):883-893. PubMed PMID: 37408495
• Janosy NR, DeBoer EM, Prager JD, Vogeli J, Wine T, Beacham AO. Social support moderates the relationship between burnout and job satisfaction in aerodigestive team members. Int J Pediatr Otorhinolaryngol. 2023 Jul;170:111602. PubMed PMID: 37224738
• Sowa LE, Stillwell PC, Houin PR, Nguyen N, Prager JD, Wine T, Teynor NJ, Meier M, Hanson RB, Francom C, Gitomer SA. Prophylactic inhaled corticosteroids for the management of recurrent croup. Int J Pediatr Otorhinolaryngol. 2023 Jul;170:111600. PubMed PMID: 37201337

Professional Memberships

• American Academy of Otolaryngology, Member

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation

• University of Colorado Hospital

Specialty Information

Specialties

• Otolaryngology - Head & Neck Surgery, Board Certification (2008)

Conditions & Treatments

• Ear, Nose, and Throat (ENT)
• Ear, Nose, and Throat (ENT) - Hearing Loss