Andreas Brieke, MD

Professional Titles

• Medical Director: Mechanical Circulatory Support Program
• Director: Advanced Heart Failure and Transplant Fellowship
• Professor of Clinical Practice

Recognitions

• Faculty of the Year, Cardiology Fellows University of Colorado (2008)
• Best Doctor: Advanced Heart Failure and Transplant, 5280 Magazine (2018)
• Best Doctor: Advanced Heart Failure and Transplant, 5280 Magazine (2017)
• Best Doctor: Advanced Heart Failure and Transplant, 5280 Magazine (2023)

Publications

• Andreas Brieke, Joseph Cleveland, Jr, JoAnn Lindenfeld: Mechanical Support in Acute and Chronic Heart Failure Current Cardiology Reports
• Page RL, Ruscin JM, Bainbridge JL, Brieke A.: Restless legs syndrome induced by escitalopram: case report and review of the literature. Pharmacotherapy. 2008 Feb;28(2):271-80.
• Lowes BD, Zolty R, Shakar SF, Brieke A, Gray N, Reed M, Calalb M, Minobe W, Lindenfeld J, Wolfel EE, Geraci M, Bristow MR, Cleveland J Jr.: Assist devices fail to reverse patterns of fetal gene expression despite beta-blockers. J Heart Lung Transplant 2007 Nov;26(11):1170-6.
• Cleveland JC Jr, Grover FL, Fullerton DA, Campbell DN, Mitchell MB, Lindenfeld J, Wolfel EE, Lowes BD, Shakar SF, Brieke A, Cannon A, Robertson AD: Left ventricular assist device as bridge to transplantation does not adversely affect one-year heart transplantation survival J Thorac Cardiovasc Surg. 2008 Sep;136(3):774
• Brieke A, Krishnamani R, Rocha MJ, Li W, Patten RD, Konstam MA, Patel AR, Udelson JE, Denofrio D: Influence of donor cocaine use on outcome after cardiac transplantation: analysis of the United Network for Organ Sharing Thoracic Registry. J Heart Lung Transplant. 2008 Dec;27(12):1350-2
• Chronic kidney disease in Cardiac Transplantation Andreas Brieke MD, Brian D. Lowes MD, Simon F. Shakar MD
• Eric Young, Ronald Zolty, Andreas Brieke, Christopher Stees, Debra Ferguson, Wayne Minobe, Simon Shakar, Michael Bristow, Brian Lowes: Down-Regulation of Connexin43 in Heart Failure is reversed by beta-Blocker Therapy. Journal of Cardiac Failure, Vol 14, No 6S 2008
• Andreas Brieke, Simon F. Shakar, Ronald Zolty, Wayne Minobe, Michael Bristow, Brian D. Lowes: Molecular Remodeling on Beta-Blocker Therapy in the Failing Human Heart, ISHLT Paris, April 2009
• Amrut V. Ambardekar MD, Brian Lowes MD, Andreas Brieke MD: Ectopy Sucks: Overdrive pacing suppresses ectopy and minimizes left ventricular assist device suction events: submitted to Circulation Imaging
• Christopher S. Stees, Eric Young, Andreas Brieke, Simon Shakar, Ronald Zolty, Doug Borg, Robert Quaife, Mara A. Kelly, Wayne Minobe, Debra Ferguson, Edward M. Gilbert*, Michael Bristow, and Brian D. Lowes: Molecular Remodeling in Wide QRS Heart Failure: Differences in Myocardial Gene Expression vs. Patients with Narrow: submitted to JACC
• Overdrive pacing suppresses ectopy and minimizes left ventricular assist device suction events. Ambardekar AV, Lowes B, Cleveland JC Jr, Brieke A. Circ Heart Fail. 2009 Sep;2(5):516-7. No abstract available. PMID: 19808384 [PubMed - indexed for MEDLINE]
• Implantable Cardioverter-Defibrillator Events in Patients with Left Ventricular Assist Devices Amrut V. Ambardekara, William H. Sauera, Andreas Briekea, Christopher M. Lowerya and Larry A. Allena Journal of Cardiac Failure Volume 15, Issue 6, Supplement 1, August 2009, Pages S47-S48 Abstracts From the 13th Annual Scientific Meeting Heart Failure Society of America September 13-16, 2009
• Effect of Left Ventricular Assist Device Placement on Preexisting Implantable Cardioverter-defibrillator Leads In Press Corrected Proof , Available online 11 January 2010 Amrut V. Ambardekar, Christopher M. Lowery, Larry A. Allen, Anne P. Cannon, Joseph C. Cleveland, Joann Lindenfeld, Andreas Brieke, William H. Sauer Journal of Cardiac Failure
• Successful Treatment of Sarcoid Related Ventricular Tachycardia Storm with Immunosuppression and Catheter Ablation Stees, Christopher S.,Sauer, William H., Bargas, Royce,Brieke, Andreas, Weinberger, Howard, Khoo, Michelle S. C. Journal of Cardiac Failure Volume 15, Issue 6, Supplement 1, August 2009, Pages S58-S59
• Molecular Predictors of
  -Blocker Response Eric Young, Christopher S Stees, Andreas Brieke, Simon Shakar, Ronald ZoltyUniv of Colorado Denver, Aurora, CO;, Albert Einstein College of Medicine, New York, NY; Douglas Borg, Robert Quaife, Mara Kelly, Wayne A Minobe, Univ of Colorado Denver, Aurora, CO; Edward M Gilbert, Univ of Utah, Salt Lake City, UT; Michael R Bristow, Brian D Lowes; Univ of Colorado Denver, Aurora, CO BCVS Conference 2009 Abstracts
• Ambardekar AV, Cannon AP, Cleveland JC Jr, Brieke A, Lindenfeld J. Driving with a driveline: a survey of current practice patterns for allowing a patient supported with a left ventricular assist device to drive. J Heart Lung Transplant. 2011 Oct;30(10):1204-5.
• Page RL 2nd, Luna M, Brieke A, Lindenfeld J Low dose Gabapentin for intractable hiccups in heart transplant recipient Progress in Transplantation 2011; 21(4):340-43
• Renin-Angiotensin System (RAS) Blockade Reduces Proteinuria in Heart Transplant Recipients: An Observational, Longitudinal Analysis Courtney Shakowski, PharmD1; Robert Lee Page II, PharmD, MSPH1,2,3; Simon Shakar, MD4, Eugene E. Wolfel, MD4, Andreas Brieke, MD4, JoAnn Lindenfeld, MD4 Accepted at ISHLT 2013
• Impact of SLCO1B1 genotype on the drug-drug interaction between cyclosporine and pravastatin: a proof-of-concept study Christina L. Aquilante, Pharm.D., Robert L. Page, Pharm.D., MSPH, Andreas Brieke, M.D., Charles W. Hopley, M.D., Uwe Christians, M.D., Ph.D., Keith L. Hoffman, B.S., Björn Schniedewind Accepted at ISHLT 2013
• Approaches to Patient Decision Making and Preparation for Destination Therapy Left Ventricular Assist Device: A Nationwide Sampling of Mechanical Circulatory Support Coordinators Authors: Colleen K. McIlvennan, DNP, Mahav Narayan, Anne Cannon, BSN, William Bradley, RN, Carolyn Nowels, MSPH, Andreas Brieke, MD, Joseph C. Cleveland, MD, Daniel D. Matlock, MD, MPH, Larry A. Allen, MD, MHS Accepted at Quality of Care and Outcomes Research in Cardiovascular Disease and Stroke 2013 Scientific Sessions
• McIlvennan CK, Page RL 2nd, Ambardekar AV, Brieke A, Lindenfeld J. Activated partial thromboplastin time overestimates anti-coagulation in left ventricular assist device patients. J Heart Lung Transplant. 2014 Dec;33(12):1312-4. PubMed PMID: 25443872
• McIlvennan CK, Allen LA, Nowels C, Brieke A, Cleveland JC, Matlock DD. Decision making for destination therapy left ventricular assist devices: "there was no choice" versus "I thought about it an awful lot". Circ Cardiovasc Qual Outcomes. 2014 May;7(3):374-80. PubMed PMID: 24823949
• Borne RT, Babu A, Levi M, Brieke A, Quaife RA. Tropheryma whipplei Endocarditis: A Two-patient Case Series. Am J Med. 2015 Dec;128(12):1364-6. PubMed PMID: 26239095
• Patel AC, Dodson RB, Cornwell WK 3rd, Hunter KS, Cleveland JC Jr, Brieke A, Lindenfeld J, Ambardekar AV. Dynamic Changes in Aortic Vascular Stiffness in Patients Bridged to Transplant With Continuous-Flow Left Ventricular Assist Devices. JACC Heart Fail. 2017 Mar 4. [Epub ahead of print] PubMed PMID: 28285118
• Maltais S, Kilic A, Nathan S, Keebler M, Emani S, Ransom J, Katz JN, Sheridan B, Brieke A, Egnaczyk G, Entwistle JW 3rd, Adamson R, Stulak J, Uriel N, O'Connell JB, Farrar DJ, Sundareswaran KS, Gregoric I. PREVENtion of HeartMate II Pump Thrombosis Through Clinical Management: The PREVENT multi-center study. J Heart Lung Transplant. 2017 Jan;36(1):1-12. PubMed PMID: 27865732
• McIlvennan CK, Babu AN, Brieke A, Ambardekar AV. Concomitant surgical cryoablation for refractory ventricular tachycardia and left ventricular assist device placement: a dual remedy but a recipe for thrombosis?. J Cardiothorac Surg. 2016 Apr 11;11(1):53. PubMed PMID: 27067868
• Patel AC, Dodson RB, Cornwell WK 3rd, Hunter KS, Cleveland JC Jr, Brieke A, Lindenfeld J, Ambardekar AV. Dynamic Changes in Aortic Vascular Stiffness in Patients Bridged to Transplant With Continuous-Flow Left Ventricular Assist Devices. JACC Heart Fail. 2017 Jun;5(6):449-459. PubMed PMID: 28285118
• Flint K, Brieke A, Wiktor D, Carroll J. Percutaneous edge-to-edge mitral valve repair may rescue select patients in cardiogenic shock: Findings from a single center case series. Catheter Cardiovasc Interv. 2019 Jan 24. [Epub ahead of print] PubMed PMID: 30677212
• Stone GW, Lindenfeld J, Abraham WT, Kar S, Lim DS, Mishell JM, Whisenant B, Grayburn PA, Rinaldi M, Kapadia SR, Rajagopal V, Sarembock IJ, Brieke A, Marx SO, Cohen DJ, Weissman NJ, Mack MJ. Transcatheter Mitral-Valve Repair in Patients with Heart Failure. N Engl J Med. 2018 Dec 13;379(24):2307-2318. PubMed PMID: 30280640
• Mehra MR, Goldstein DJ, Uriel N, Cleveland JC Jr, Yuzefpolskaya M, Salerno C, Walsh MN, Milano CA, Patel CB, Ewald GA, Itoh A, Dean D, Krishnamoorthy A, Cotts WG, Tatooles AJ, Jorde UP, Bruckner BA, Estep JD, Jeevanandam V, Sayer G, Horstmanshof D, Long JW, Gulati S, Skipper ER, O'Connell JB, Heatley G, Sood P, Naka Y. Two-Year Outcomes with a Magnetically Levitated Cardiac Pump in Heart Failure. N Engl J Med. 2018 Apr 12;378(15):1386-1395. PubMed PMID: 29526139
• Maltais S, Kilic A, Nathan S, Keebler M, Emani S, Ransom J, Katz JN, Sheridan B, Brieke A, Egnaczyk G, Entwistle JW 3rd, Adamson R, Stulak J, Uriel N, O'Connell JB, Farrar DJ, Sundareswaran KS, Gregoric I. PREVENtion of HeartMate II Pump Thrombosis Through Clinical Management: The PREVENT multi-center study. J Heart Lung Transplant. 2017 Jan;36(1):1-12. PubMed PMID: 27865732
• Purohit SN, Lee PJ, Strobel AL, Desai AA, Marsala MT, Bull TM, Brieke A, Vargas D, Kay JD, Altman NL. Unusual Case of Acquired Hypoxemia Following Left Ventricular Assist Device Implantation. Circ Heart Fail. 2020 Jan;13(1):e006394. PubMed PMID: 31896269
• Baron SJ, Wang K, Arnold SV, Magnuson EA, Whisenant B, Brieke A, Rinaldi M, Asgar AW, Lindenfeld J, Abraham WT, Mack MJ, Stone GW, Cohen DJ. Cost-Effectiveness of Transcatheter Mitral Valve Repair Versus Medical Therapy in Patients With Heart Failure and Secondary Mitral Regurgitation: Results From the COAPT Trial. Circulation. 2019 Dec 3;140(23):1881-1891. PubMed PMID: 31564137
• Flint KM, Brieke A, Cornwell WK 3rd, Pierce C, Cleveland JC, Pal JD. HeartMate II System Controller Failure Presenting as Driveline Fault With Repeated Pump Stoppages. Circ Heart Fail. 2019 Jul;12(7):e005738. PubMed PMID: 31213070
• Flint K, Brieke A, Wiktor D, Carroll J. Percutaneous edge-to-edge mitral valve repair may rescue select patients in cardiogenic shock: Findings from a single center case series. Catheter Cardiovasc Interv. 2019 Aug 1;94(2):E82-E87. PubMed PMID: 30677212
• Mack MJ, Lindenfeld J, Abraham WT, Kar S, Lim DS, Mishell JM, Whisenant BK, Grayburn PA, Rinaldi MJ, Kapadia SR, Rajagopal V, Sarembock IJ, Brieke A, Rogers JH, Marx SO, Cohen DJ, Weissman NJ, Stone GW. 3-Year Outcomes of Transcatheter Mitral Valve Repair in Patients With Heart Failure. J Am Coll Cardiol. 2021 Mar 2;77(8):1029-1040. PubMed PMID: 33632476
• Lerakis S, Kini AS, Asch FM, Kar S, Lim DS, Mishell JM, Whisenant B, Grayburn PA, Weissman NJ, Rinaldi MJ, Sharma SK, Kapadia SR, Rajagopal V, Sarembock IJ, Brieke A, Tang GHL, Li D, Crowley A, Lindenfeld J, Abraham WT, Mack MJ, Stone GW. Outcomes of Transcatheter Mitral Valve Repair for Secondary Mitral Regurgitation by Severity of Left Ventricular Dysfunction. EuroIntervention. 2021 Feb 16. [Epub ahead of print] PubMed PMID: 33589408
• Kosmidou I, Lindenfeld J, Abraham WT, Rinaldi MJ, Kapadia SR, Rajagopal V, Sarembock IJ, Brieke A, Gaba P, Rogers JH, Shahim B, Redfors B, Zhang Z, Mack MJ, Stone GW. Sex-Specific Outcomes of Transcatheter Mitral-Valve Repair and Medical Therapy for Mitral Regurgitation in Heart Failure. JACC Heart Fail. 2021 Sep;9(9):674-683. PubMed PMID: 34391744
• Cowger JA, Estep JD, Rinde-Hoffman DA, Givertz MM, Anderson AS, Jacoby D, Chen L, Brieke A, Mahr C, Hall S, Ewald GA, Dirckx N, Baker AT, Pinney SP. Variability in Blood Pressure Assessment in Patients Supported with the HeartMate 3TM. ASAIO J. 2022 Mar 1;68(3):374-383. PubMed PMID: 34172641
• Mack MJ, Lindenfeld J, Abraham WT, Kar S, Lim DS, Mishell JM, Whisenant BK, Grayburn PA, Rinaldi MJ, Kapadia SR, Rajagopal V, Sarembock IJ, Brieke A, Rogers JH, Marx SO, Cohen DJ, Weissman NJ, Stone GW. 3-Year Outcomes of Transcatheter Mitral Valve Repair in Patients With Heart Failure. J Am Coll Cardiol. 2021 Mar 2;77(8):1029-1040. PubMed PMID: 33632476
• Lerakis S, Kini AS, Asch FM, Kar S, Lim DS, Mishell JM, Whisenant B, Grayburn PA, Weissman NJ, Rinaldi MJ, Sharma SK, Kapadia SR, Rajagopal V, Sarembock IJ, Brieke A, Tang GHL, Li D, Crowley A, Lindenfeld J, Abraham WT, Mack MJ, Stone GW. Outcomes of transcatheter mitral valve repair for secondary mitral regurgitation by severity of left ventricular dysfunction. EuroIntervention. 2021 Jul 20;17(4):e335-e342. PubMed PMID: 33589408
• Cowger JA, Estep JD, Rinde-Hoffman DA, Givertz MM, Anderson AS, Jacoby D, Chen L, Brieke A, Mahr C, Hall S, Ewald GA, Dirckx N, Baker AT, Pinney SP. Variability in Blood Pressure Assessment in Patients Supported with the HeartMate 3TM. ASAIO J. 2022 Mar 1;68(3):374-383. PubMed PMID: 34172641
• Pal JD, Cleveland J, Reece BT, Byrd J, Pierce CN, Brieke A, Cornwell WK 3rd. Cardiac Emergencies in Patients with Left Ventricular Assist Devices. Heart Fail Clin. 2020 Jul;16(3):295-303. PubMed PMID: 32503753
• Purohit SN, Lee PJ, Strobel AL, Desai AA, Marsala MT, Bull TM, Brieke A, Vargas D, Kay JD, Altman NL. Unusual Case of Acquired Hypoxemia Following Left Ventricular Assist Device Implantation. Circ Heart Fail. 2020 Jan;13(1):e006394. PubMed PMID: 31896269
• Kim G, Sayer G, Ransom J, Keebler M, Katz J, Kilic A, Lindenfeld J, Egnaczyk G, Shah P, Brieke A, Walenga J, Crandall D, Farrar DJ, Sundareswaran K, Uriel N. Association of Angiopoetin-2 and TNF-a With Bleeding During Left Ventricular Assist Device Support: Analysis From the PREVENT Biorepository. ASAIO J. 2023 Aug 1;69(8):742-748. PubMed PMID: 37134003
• Stone GW, Abraham WT, Lindenfeld J, Kar S, Grayburn PA, Lim DS, Mishell JM, Whisenant B, Rinaldi M, Kapadia SR, Rajagopal V, Sarembock IJ, Brieke A, Marx SO, Cohen DJ, Asch FM, Mack MJ. Five-Year Follow-up after Transcatheter Repair of Secondary Mitral Regurgitation. N Engl J Med. 2023 Jun 1;388(22):2037-2048. PubMed PMID: 36876756
• Jeske W, Ransom J, Katz JN, Kilic A, Lindenfeld J, Egnaczyk G, Shah P, Brieke A, Uriel N, Crandall D, Farrar DJ, Walenga JM. Enhanced Thrombin Formation in Patients With Ventricular Assist Devices Experiencing Bleeding: Insights From the Multicenter PREVENT Study. ASAIO J. 2023 Mar 1;69(3):278-283. PubMed PMID: 36731068

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

UCHealth Heart & Vascular Center - Anschutz
12505 E. 16th Ave
Anschutz Inpatient Pavilion 2, 3rd floor
Aurora, CO 80045
720-848-5300

UCHealth Heart Failure Program - Anschutz
12505 E. 16th Ave
Anschutz Inpatient Pavilion 2, 3rd floor
Aurora, CO 80045
720-848-5300

Hospital Affiliation

• University of Colorado Hospital

Center Affiliations

• Colorado Clinical & Translational Sciences Institute (CCTSI)

Specialty Information

Specialties

• Internal Medicine (2002)
• Advanced Heart Failure and Transplant Cardiology, Board Certification (2010)
• Cardiology, Board Certification (2006, 2016)
• Mechanical Circulatory Support, Certificate (0001)

Conditions & Treatments

• Heart and Circulation - Cardiomyopathy
• Heart and Circulation - Heart Failure
• Heart and Circulation - Heart Diseases
• Heart and Circulation
• Heart and Circulation - Heart Valve Diseases
• Surgery - Heart Transplant Surgery
• Surgery