David Fleischer, MD
Professor, Pediatrics-Allergy/Immunology

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Medical School:
  • MD, Emory University School of Medicine (1997)
Undergraduate School:
  • BA, University of Pennsylvania (Philadelphia, PA) (1992)
Internship:
  • Johns Hopkins University School of Medicine Program (1998)
Residency:
  • Johns Hopkins University School of Medicine Program, Pediatrics (2000)
Fellowships:
  • Johns Hopkins University School of Medicine Program, Pediatric Allergy and Immunology (2005)
Languages: English
Department: Pediatrics-Allergy/Immunology

Professional Titles

  • Section Head, Allergy and Immunology
  • Director, Allergy and Immunology Center

Research Interests

My research focuses on food allergy, in particular peanut and tree nut allergies. I am interested in why certain patients with food allergies outgrow them more readily and sooner than others. I am an investigator in treatments for food allergy, including oral, sublingual, and epicutaneous immunotherapies.

Teaching

  • Professor of Pediatrics (2020)
    School of Medicine, Pediatrics

Publications

  • Venter C, Palumbo MP, Glueck DH, Sauder KA, Perng W, O'Mahony L, Pickett K, Greenhawt M, Fleischer DM, Dabelea D. Comparing the Diagnostic Accuracy of Measures of Maternal Diet During Pregnancy for Offspring Allergy Outcomes: The Healthy Start Study. J Allergy Clin Immunol Pract. 2023 Jan;11(1):255-263.e1. PubMed PMID: 36150675
  • Venter C, Shamir R, Fleischer DM. Early Introduction of Novel and Less-Studied Food Allergens in the Plant-Based Era: Considerations for US and EU Infant Formula Regulations. Nutrients. 2023 Oct 25;15(21). PubMed PMID: 37960183
  • Santos AF, Riggioni C, Agache I, Akdis CA, Akdis M, Alvarez-Perea A, Alvaro-Lozano M, Ballmer-Weber B, Barni S, Beyer K, Bindslev-Jensen C, Brough HA, Buyuktiryaki B, Chu D, Del Giacco S, Dunn-Galvin A, Eberlein B, Ebisawa M, Eigenmann P, Eiwegger T, Feeney M, Fernandez-Rivas M, Fisher HR, Fleischer DM, Giovannini M, Gray C, Hoffmann-Sommergruber K, Halken S, Hourihane JO, Jones CJ, Jutel M, Knol E, Konstantinou GN, Lack G, Lau S, Marques Mejias A, Marchisotto MJ, Meyer R, Mortz CG, Moya B, Muraro A, Nilsson C, Lopes de Oliveira LC, O'Mahony L, Papadopoulos NG, Perrett K, Peters RL, Podesta M, Poulsen LK, Roberts G, Sampson HA, Schwarze J, Smith P, Tham EH, Untersmayr E, Van Ree R, Venter C, Vickery BP, Vlieg-Boerstra B, Werfel T, Worm M, Du Toit G, Skypala I. EAACI guidelines on the diagnosis of IgE-mediated food allergy. Allergy. 2023 Dec;78(12):3057-3076. PubMed PMID: 37815205
  • Davis CM, Lange L, Beyer K, Fleischer DM, Ford L, Sussman G, Oriel RC, Pongracic JA, Shreffler W, Bee KJ, Campbell DE, Green TD, Lambert R, Peillon A, Bégin P. Efficacy and safety of peanut epicutaneous immunotherapy in patients with atopic comorbidities. J Allergy Clin Immunol Glob. 2023 Feb;2(1):69-75. PubMed PMID: 37780103
  • Chua GT, Greenhawt M, Shaker M, Soller L, Abrams EM, Cameron SB, Cook VE, Erdle SC, Fleischer DM, Mak R, Vander Leek TK, Chan ES. Real-world data are critical for the implementation of preschool food allergen immunotherapy. J Allergy Clin Immunol Pract. 2023 Aug;11(8):2624-2625. PubMed PMID: 37558366
  • Venter C, Smith PK, Fleischer DM. Food allergy prevention: Where are we in 2023?. Asia Pac Allergy. 2023 Mar;13(1):15-27. PubMed PMID: 37389093
  • Greenhawt M, Dribin TE, Abrams EM, Shaker M, Chu DK, Golden DBK, Akin C, Anagnostou A, ALMuhizi F, Alqurashi W, Arkwright P, Baldwin JL, Banerji A, Bégin P, Ben-Shoshan M, Bernstein J, Bingemann TA, Bindslev-Jensen C, Blumenthal K, Byrne A, Cahill J, Cameron S, Campbell D, Campbell R, Cavender M, Chan ES, Chinthrajah S, Comberiati P, Eastman JJ, Ellis AK, Fleischer DM, Fox A, Frischmeyer-Guerrerio PA, Gagnon R, Garvey LH, Grayson MH, Isabwe GAC, Hartog N, Hendron D, Horner CC, Hourihane JO, Iglesia E, Kan M, Kaplan B, Katelaris CH, Kim H, Kelso JM, Khan DA, Lang D, Ledford D, Levin M, Lieberman JA, Loh R, Mack DP, Mazer B, Mody K, Mosnaim G, Munblit D, Mustafa SS, Nanda A, Nathan R, Oppenheimer J, Otani IM, Park M, Pawankar R, Perrett KP, Peter J, Phillips EJ, Picard M, Pitlick M, Ramsey A, Rasmussen TH, Rathkopf MM, Reddy H, Robertson K, Rodriguez Del Rio P, Sample S, Sheshadri A, Sheik J, Sindher SB, Spergel JM, Stone CA, Stukus D, Tang MLK, Tracy JM, Turner PJ, Vander Leek TK, Wallace DV, Wang J, Wasserman S, Weldon D, Wolfson AR, Worm M, Yacoub MR. Updated guidance regarding the risk of allergic reactions to COVID-19 vaccines and recommended evaluation and management: A GRADE assessment and international consensus approach. J Allergy Clin Immunol. 2023 Aug;152(2):309-325. PubMed PMID: 37295474
  • Greenhawt M, Sindher SB, Wang J, O'Sullivan M, du Toit G, Kim EH, Albright D, Anvari S, Arends N, Arkwright PD, Bégin P, Blumchen K, Bourrier T, Brown-Whitehorn T, Cassell H, Chan ES, Ciaccio CE, Deschildre A, Divaret-Chauveau A, Dorris SL, Dorsey MJ, Eiwegger T, Erlewyn-Lajeunesse M, Fleischer DM, Ford LS, Garcia-Lloret M, Giovannini-Chami L, Hourihane JO, Jay N, Jones SM, Kerns LA, Kloepfer KM, Leonard S, Lezmi G, Lieberman JA, Lomas J, Makhija M, Parrish C, Peake J, Perrett KP, Petroni D, Pfützner W, Pongracic JA, Quinn P, Robison RG, Sanders G, Schneider L, Sharma HP, Trujillo J, Turner PJ, Tuttle K, Upton JE, Varshney P, Vickery BP, Vogelberg C, Wainstein B, Wood RA, Bee KJ, Campbell DE, Green TD, Rouissi R, Peillon A, Bahnson HT, Bois T, Sampson HA, Burks AW. Phase 3 Trial of Epicutaneous Immunotherapy in Toddlers with Peanut Allergy. N Engl J Med. 2023 May 11;388(19):1755-1766. PubMed PMID: 37163622
  • Bastin M, Carr WW, Davis CM, Fleischer DM, Lieberman JA, Mustafa SS, Helleputte T, Bois T, Campbell DE, Green TD, Greenhawt M. Immune response evolution in peanut epicutaneous immunotherapy for peanut-allergic children. Allergy. 2023 Sep;78(9):2467-2476. PubMed PMID: 36916639
  • Venter C, Palumbo MP, Glueck DH, Sauder KA, Perng W, O'Mahony L, Pickett K, Greenhawt M, Fleischer DM, Dabelea D. Comparing the Diagnostic Accuracy of Measures of Maternal Diet During Pregnancy for Offspring Allergy Outcomes: The Healthy Start Study. J Allergy Clin Immunol Pract. 2023 Jan;11(1):255-263.e1. PubMed PMID: 36150675
  • Chua GT, Greenhawt M, Shaker M, Soller L, Abrams EM, Cameron SB, Cook VE, Erdle SC, Fleischer DM, Mak R, Vander Leek TK, Chan ES. Reply to "Peanut allergy prevention: A mother's perspective". J Allergy Clin Immunol Pract. 2023 May;11(5):1574-1575. PubMed PMID: 37150549
  • Pongracic JA, Gagnon R, Sussman G, Siri D, Oriel RC, Brown-Whitehorn TF, Green TD, Campbell DE, Anvari S, Berger WE, Bird JA, Chan ES, Cheema A, Chinthrajah RS, Chong HJ, Dowling PJ, Fineman SM, Fleischer DM, Gonzalez-Reyes E, Kim EH, Lanser BJ, MacGinnitie A, Mehta H, Petroni D, Rupp N, Schneider LC, Scurlock AM, Sher LD, Shreffler WG, Sindher SB, Stillerman A, Wood R, Yang WH, Bois T, Sampson HA, Bégin P. Safety of Epicutaneous Immunotherapy in Peanut-Allergic Children: REALISE Randomized Clinical Trial Results. J Allergy Clin Immunol Pract. 2022 Jul;10(7):1864-1873.e10. PubMed PMID: 34848381
  • Venter C, Palumbo MP, Sauder KA, Glueck DH, O'Mahony L, Yang I, Davidson EJ, Brough HA, Holloway JW, Fleischer DM, Ben-Abdallah M, Dabelea D. Associations between child filaggrin mutations and maternal diet with the development of allergic diseases in children. Pediatr Allergy Immunol. 2022 Mar;33(3):e13753. PubMed PMID: 35338739
  • Lins de Holanda Coelho G, DunnGalvin A, Greenhawt M, Hourihane JO, Fleischer DM, Chen G, Shaker M, Campbell DE, Green TD, Bégin P. Psychometric parameters of food allergy quality of life during an allergen immunotherapy trial. Allergy. 2022 Sep;77(9):2770-2777. PubMed PMID: 35466405
  • Chua GT, Greenhawt M, Shaker M, Soller L, Abrams EM, Cameron SB, Cook VE, Erdle SC, Fleischer DM, Mak R, Vander Leek TK, Chan ES. The Case for Prompt Salvage Infant Peanut Oral Immunotherapy Following Failed Primary Prevention. J Allergy Clin Immunol Pract. 2022 Oct;10(10):2561-2569. PubMed PMID: 35752433
  • Meyer R, Vandenplas Y, Lozinsky AC, Vieira MC, Canani RB, Dupont C, Uysal P, Cavkaytar O, Knibb R, Fleischer DM, Nowak-Wegrzyn A, Venter C. Diagnosis and management of food allergy-associated gastroesophageal reflux disease in young children-EAACI position paper. Pediatr Allergy Immunol. 2022 Oct;33(10):e13856. PubMed PMID: 36282131
  • Bégin P, Bird JA, Spergel JM, Campbell DE, Green TD, Bee KJ, Lambert R, Sampson HA, Fleischer DM. Reduction in peanut reaction severity during oral challenge after 12 months of epicutaneous immunotherapy. Allergy. 2021 Sep 7. [Epub ahead of print] PubMed PMID: 34492123
  • Friedlander JA, Fleischer DM, Black JO, Levy M, Rothenberg ME, Smith C, Nguyen N, Pan Z, Furuta GT. Unsedated transnasal esophagoscopy with virtual reality distraction enables earlier monitoring of dietary therapy in eosinophilic esophagitis. J Allergy Clin Immunol Pract. 2021 Sep;9(9):3494-3496. PubMed PMID: 34224927
  • Greenhawt M, Abrams EM, Shaker M, Chu DK, Khan D, Akin C, Alqurashi W, Arkwright P, Baldwin JL, Ben-Shoshan M, Bernstein J, Bingemann T, Blumchen K, Byrne A, Bognanni A, Campbell D, Campbell R, Chagla Z, Chan ES, Chan J, Comberiati P, Dribin TE, Ellis AK, Fleischer DM, Fox A, Frischmeyer-Guerrerio PA, Gagnon R, Grayson MH, Horner CC, Hourihane J, Katelaris CH, Kim H, Kelso JM, Lang D, Ledford D, Levin M, Lieberman J, Loh R, Mack D, Mazer B, Mosnaim G, Munblit D, Mustafa SS, Nanda A, Oppenheimer J, Perrett KP, Ramsey A, Rank M, Robertson K, Sheikh J, Spergel JM, Stukus D, Tang MLK, Tracy JM, Turner PJ, Whalen-Browne A, Wallace D, Wang J, Waserman S, Witry JK, Worm M, Vander Leek TK, Golden DBK. The Risk of Allergic Reaction to SARS-CoV-2 Vaccines and Recommended Evaluation and Management: A Systematic Review, Meta-Analysis, GRADE Assessment, and International Consensus Approach. J Allergy Clin Immunol Pract. 2021 Oct;9(10):3546-3567. PubMed PMID: 34153517
  • Venter C, Palumbo MP, Glueck DH, Sauder KA, O'Mahony L, Fleischer DM, Ben-Abdallah M, Ringham BM, Dabelea D. The maternal diet index in pregnancy is associated with offspring allergic diseases: the Healthy Start study. Allergy. 2021 May 21. [Epub ahead of print] PubMed PMID: 34018205
  • Waserman S, Cruickshank H, Hildebrand KJ, Mack D, Bantock L, Bingemann T, Chu DK, Cuello-Garcia C, Ebisawa M, Fahmy D, Fleischer DM, Galloway L, Gartrell G, Greenhawt M, Hamilton N, Hourihane J, Langlois M, Loh R, Muraro A, Rosenfield L, Schoessler S, Tang MLK, Weitzner B, Wang J, Brozek JL. Prevention and management of allergic reactions to food in child care centers and schools: Practice guidelines. J Allergy Clin Immunol. 2021 May;147(5):1561-1578. PubMed PMID: 33965093
  • Venter C, Palumbo MP, Sauder KA, Glueck DH, Liu AH, Yang IV, Ben-Abdallah M, Fleischer DM, Dabelea D. Incidence and timing of offspring asthma, wheeze, allergic rhinitis, atopic dermatitis, and food allergy and association with maternal history of asthma and allergic rhinitis. World Allergy Organ J. 2021 Mar;14(3):100526. PubMed PMID: 33767802
  • Remington BC, Campbell DE, Green TD, Fleischer DM, Koppelman SJ. Post hoc analysis of epicutaneous immunotherapy for peanut allergy phase 3 results: Relevance for exposure through restaurant meals. Ann Allergy Asthma Immunol. 2021 Feb;126(2):208-209. PubMed PMID: 33259921
  • Fleischer DM, Chan ES, Venter C, Spergel JM, Abrams EM, Stukus D, Groetch M, Shaker M, Greenhawt M. A Consensus Approach to the Primary Prevention of Food Allergy Through Nutrition: Guidance from the American Academy of Allergy, Asthma, and Immunology; American College of Allergy, Asthma, and Immunology; and the Canadian Society for Allergy and Clinical Immunology. J Allergy Clin Immunol Pract. 2021 Jan;9(1):22-43.e4. PubMed PMID: 33250376
  • DunnGalvin A, Fleischer DM, Campbell DE, O'B Hourihane J, Green TD, Sampson HA, Greenhawt M. Improvements in Quality of Life in Children Following Epicutaneous Immunotherapy (EPIT) for Peanut Allergy in the PEPITES and PEOPLE Studies. J Allergy Clin Immunol Pract. 2021 Jan;9(1):216-224.e1. PubMed PMID: 32841748
  • Greiwe J, Oppenheimer J, Bird JA, Fleischer DM, Pongracic JA, Greenhawt M. AAAAI Work Group Report: Trends in Oral Food Challenge Practices Among Allergists in the United States. J Allergy Clin Immunol Pract. 2020 Nov - Dec;8(10):3348-3355. PubMed PMID: 33161964
  • DunnGalvin A, Fleischer DM, Campbell DE, O'B Hourihane J, Green TD, Sampson HA, Greenhawt M. Improvements in Quality of Life in Children Following Epicutaneous Immunotherapy (EPIT) for Peanut Allergy in the PEPITES and PEOPLE Studies. J Allergy Clin Immunol Pract. 2020 Aug 22. [Epub ahead of print] PubMed PMID: 32841748
  • Mack DP, Chan ES, Shaker M, Abrams EM, Wang J, Fleischer DM, Hanna MA, Greenhawt M. Novel Approaches to Food Allergy Management During COVID-19 Inspire Long-Term Change. J Allergy Clin Immunol Pract. 2020 Oct;8(9):2851-2857. PubMed PMID: 32721605
  • Greenhawt M, Shaker M, Stukus DR, Fleischer DM, Hourihane J, Tang MLK, Abrams EM, Wang J, Bingemann TA, Chan ES, Lieberman J, Sampson HA, Bock SA, Young MC, Waserman S, Mack DP. Managing Food Allergy in Schools During the COVID-19 Pandemic. J Allergy Clin Immunol Pract. 2020 Oct;8(9):2845-2850. PubMed PMID: 32711118
  • Fleischer DM, Shreffler WG, Campbell DE, Green TD, Anvari S, Assa'ad A, Bégin P, Beyer K, Bird JA, Brown-Whitehorn T, Byrne A, Chan ES, Cheema A, Chinthrajah S, Chong HJ, Davis CM, Ford LS, Gagnon R, Greenhawt M, Hourihane JO, Jones SM, Kim EH, Lange L, Lanser BJ, Leonard S, Mahler V, Maronna A, Nowak-Wegrzyn A, Oriel RC, O'Sullivan M, Petroni D, Pongracic JA, Prescott SL, Schneider LC, Smith P, Staab D, Sussman G, Wood R, Yang WH, Lambert R, Peillon A, Bois T, Sampson HA. Long-term, open-label extension study of the efficacy and safety of epicutaneous immunotherapy for peanut allergy in children: PEOPLE 3-year results. J Allergy Clin Immunol. 2020 Oct;146(4):863-874. PubMed PMID: 32659313
  • Fleischer DM, Chinthrajah S, Scurlock AM, Campbell DE, Green TD, Bee KJ, Peillon A, Ocheltree T, Sampson HA. An evaluation of factors influencing response to epicutaneous immunotherapy for peanut allergy in the PEPITES trial. Allergy Asthma Proc. 2020 Sep 1;41(5):326-335. PubMed PMID: 32539908
  • Venter C, Agostoni C, Arshad SH, Ben-Abdallah M, Du Toit G, Fleischer DM, Greenhawt M, Glueck DH, Groetch M, Lunjani N, Maslin K, Maiorella A, Meyer R, Antonella M, Netting MJ, Ibeabughichi Nwaru B, Palmer DJ, Palumbo MP, Roberts G, Roduit C, Smith P, Untersmayr E, Vanderlinden LA, O'Mahony L. Dietary factors during pregnancy and atopic outcomes in childhood: A systematic review from the European Academy of Allergy and Clinical Immunology. Pediatr Allergy Immunol. 2020 Jun 10. [Epub ahead of print] PubMed PMID: 32524677
  • Fleischer DM, Spergel JM, Kim EH, Campbell DE, Green TD, Bee KJ, Lambert R, Ocheltree T, Sampson HA. Evaluation of daily patch application duration for epicutaneous immunotherapy for peanut allergy. Allergy Asthma Proc. 2020 Jul 1;41(4):278-284. PubMed PMID: 32517847
  • Greenhawt M, Kim EH, Campbell DE, Green TD, Lambert R, Fleischer DM. Improvements in eliciting dose across baseline sensitivities following 12 months of epicutaneous immunotherapy (EPIT) in peanut-allergic children aged 4 to 11 years. J Allergy Clin Immunol Pract. 2020 Oct;8(9):3219-3221. PubMed PMID: 32502548
  • Searing DA, Dutmer CM, Fleischer DM, Shaker MS, Oppenheimer J, Grayson MH, Stukus D, Hartog N, Hsieh EWY, Rider NL, Vander Leek TK, Kim H, Chan ES, Mack D, Ellis AK, Abrams EM, Bansal P, Lang DM, Lieberman J, Golden DB, Wallace D, Portnoy J, Mosnaim G, Greenhawt M. A Phased Approach to Resuming Suspended Allergy/Immunology Clinical Services. J Allergy Clin Immunol Pract. 2020 Jul - Aug;8(7):2125-2134. PubMed PMID: 32450236
  • Greenhawt M, Shaker M, Winders T, Bukstein DA, Davis RS, Oppenheimer J, Fleischer DM, Kim E, Chan ES, Stukus DR, Matlock D. Development and acceptability of a shared decision-making tool for commercial peanut allergy therapies. Ann Allergy Asthma Immunol. 2020 Jul;125(1):90-96. PubMed PMID: 32057932
  • Venter C, Maslin K, Holloway JW, Silveira LJ, Fleischer DM, Dean T, Arshad SH. Different Measures of Diet Diversity During Infancy and the Association with Childhood Food Allergy in a UK Birth Cohort Study. J Allergy Clin Immunol Pract. 2020 Jun;8(6):2017-2026. PubMed PMID: 32004745
  • Meyer R, Chebar Lozinsky A, Fleischer DM, Vieira MC, Du Toit G, Vandenplas Y, Dupont C, Knibb R, Uysal P, Cavkaytar O, Nowak-Wegrzyn A, Shah N, Venter C. Diagnosis and management of Non-IgE gastrointestinal allergies in breastfed infants-An EAACI Position Paper. Allergy. 2020 Jan;75(1):14-32. PubMed PMID: 31199517
  • Vandenplas Y, Latiff AHA, Fleischer DM, Gutiérrez-Castrellón P, Miqdady MS, Smith PK, von Berg A, Greenhawt MJ. Partially hydrolyzed formula in non-exclusively breastfed infants: A systematic review and expert consensus. Nutrition. 2019 Jan;57:268-274. PubMed PMID: 30223233
  • Remington BC, Krone T, Kim EH, Bird JA, Green TD, Lack G, Fleischer DM, Koppelman SJ. Estimated risk reduction to packaged food reactions by epicutaneous immunotherapy (EPIT) for peanut allergy. Ann Allergy Asthma Immunol. 2019 Nov;123(5):488-493.e2. PubMed PMID: 31442495
  • Meyer R, Chebar Lozinsky A, Fleischer DM, Vieira MC, Du Toit G, Vandenplas Y, Dupont C, Knibb R, Uysal P, Cavkaytar O, Nowak-Wegrzyn A, Shah N, Venter C. Diagnosis and management of Non-IgE gastrointestinal allergies in breastfed infants-An EAACI Position Paper. Allergy. 2019 Jun 14. [Epub ahead of print] PubMed PMID: 31199517
  • Abrams EM, Soller L, Singer AG, Fleischer DM, Greenhawt M, Chan ES. Comparison of practice patterns among Canadian allergists before and after NIAID guideline recommendations. J Allergy Clin Immunol Pract. 2019 Nov - Dec;7(8):2901-2903.e3. PubMed PMID: 31100554
  • Obbagy JE, English LK, Wong YP, Butte NF, Dewey KG, Fleischer DM, Fox MK, Greer FR, Krebs NF, Scanlon KS, Stoody EE. Complementary feeding and food allergy, atopic dermatitis/eczema, asthma, and allergic rhinitis: a systematic review. Am J Clin Nutr. 2019 Mar 1;109(Supplement_7):890S-934S. PubMed PMID: 30982864
  • Fleischer DM, Greenhawt M, Sussman G, Bégin P, Nowak-Wegrzyn A, Petroni D, Beyer K, Brown-Whitehorn T, Hebert J, Hourihane JO, Campbell DE, Leonard S, Chinthrajah RS, Pongracic JA, Jones SM, Lange L, Chong H, Green TD, Wood R, Cheema A, Prescott SL, Smith P, Yang W, Chan ES, Byrne A, Assa'ad A, Bird JA, Kim EH, Schneider L, Davis CM, Lanser BJ, Lambert R, Shreffler W. Effect of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Ingestion Among Children With Peanut Allergy: The PEPITES Randomized Clinical Trial. JAMA. 2019 Mar 12;321(10):946-955. PubMed PMID: 30794314
  • Chan ES, Greenhawt MJ, Fleischer DM, Caubet JC. Managing Cross-Reactivity in Those with Peanut Allergy. J Allergy Clin Immunol Pract. 2019 Feb;7(2):381-386. PubMed PMID: 30472327
  • Vandenplas Y, Latiff AHA, Fleischer DM, Gutiérrez-Castrellón P, Miqdady MS, Smith PK, von Berg A, Greenhawt MJ. Partially hydrolyzed formula in non-exclusively breastfed infants: A systematic review and expert consensus. Nutrition. 2019 Jan;57:268-274. PubMed PMID: 30223233
  • Chan ES, Greenhawt MJ, Fleischer DM, Caubet JC. Managing Cross-Reactivity in Those with Peanut Allergy. J Allergy Clin Immunol Pract. 2018 Nov 22. [Epub ahead of print] PubMed PMID: 30472327
  • Vickery BP, Vereda A, Casale TB, Beyer K, du Toit G, Hourihane JO, Jones SM, Shreffler WG, Marcantonio A, Zawadzki R, Sher L, Carr WW, Fineman S, Greos L, Rachid R, Ibáñez MD, Tilles S, Assa’ad AH, Nilsson C, Rupp N, Welch MJ, Sussman G, Chinthrajah S, Blumchen K, Sher E, Spergel JM, Leickly FE, Zielen S, Wang J, Sanders GM, Wood RA, Cheema A, Bindslev-Jensen C, Leonard S, Kachru R, Johnston DT, Hampel FC Jr, Kim EH, Anagnostou A, Pongracic JA, Ben-Shoshan M, Sharma HP, Stillerman A, Windom HH, Yang WH, Muraro A, Zubeldia JM, Sharma V, Dorsey MJ, Chong HJ, Ohayon J, Bird JA, Carr TF, Siri D, Fernández-Rivas M, Jeong DK, Fleischer DM, Lieberman JA, Dubois AEJ, Tsoumani M, Ciaccio CE, Portnoy JM, Mansfield LE, Fritz SB, Lanser BJ, Matz J, Oude Elberink HNG, Varshney P, Dilly SG, Adelman DC, Burks AW. AR101 Oral Immunotherapy for Peanut Allergy. N Engl J Med. 2018 Nov 22;379(21):1991-2001. PubMed PMID: 30449234
  • Chehade M, Jones SM, Pesek RD, Burks AW, Vickery BP, Wood RA, Leung DYM, Furuta GT, Fleischer DM, Henning AK, Dawson P, Lindblad RW, Sicherer SH, Abonia JP, Sherrill JD, Sampson HA, Rothenberg ME. Phenotypic Characterization of Eosinophilic Esophagitis in a Large Multicenter Patient Population from the Consortium for Food Allergy Research. J Allergy Clin Immunol Pract. 2018 Sep - Oct;6(5):1534-1544.e5. PubMed PMID: 30075341
  • Bird JA, Fleischer DM, Groetch M, Nowak-Wegrzyn A, Sicherer S, Young MC. Additional oral food challenge considerations. J Allergy Clin Immunol. 2018 Jun;141(6):2322. PubMed PMID: 29692338
  • Shaker M, Stukus D, Chan ES, Fleischer DM, Spergel JM, Greenhawt M. "To screen or not to screen": Comparing the health and economic benefits of early peanut introduction strategies in five countries. Allergy. 2018 Aug;73(8):1707-1714. PubMed PMID: 29601091
  • Greenhawt M, Chan ES, Fleischer DM, Hicks A, Wilson R, Shaker M, Venter C, Stukus D. Caregiver and expecting caregiver support for early peanut introduction guidelines. Ann Allergy Asthma Immunol. 2018 Jun;120(6):620-625. PubMed PMID: 29524559
  • Shreffler WG, Baumert JL, Remington BC, Koppelman SJ, Dinakar C, Fleischer DM, Kim E, Tilles SA, Spergel JM. The importance of reducing risk in peanut allergy: Current and future therapies. Ann Allergy Asthma Immunol. 2018 Feb;120(2):124-127. PubMed PMID: 29289463
  • Vickery BP, Vereda A, Casale TB, Beyer K, du Toit G, Hourihane JO, Jones SM, Shreffler WG, Marcantonio A, Zawadzki R, Sher L, Carr WW, Fineman S, Greos L, Rachid R, Ibáñez MD, Tilles S, Assa’ad AH, Nilsson C, Rupp N, Welch MJ, Sussman G, Chinthrajah S, Blumchen K, Sher E, Spergel JM, Leickly FE, Zielen S, Wang J, Sanders GM, Wood RA, Cheema A, Bindslev-Jensen C, Leonard S, Kachru R, Johnston DT, Hampel FC Jr, Kim EH, Anagnostou A, Pongracic JA, Ben-Shoshan M, Sharma HP, Stillerman A, Windom HH, Yang WH, Muraro A, Zubeldia JM, Sharma V, Dorsey MJ, Chong HJ, Ohayon J, Bird JA, Carr TF, Siri D, Fernández-Rivas M, Jeong DK, Fleischer DM, Lieberman JA, Dubois AEJ, Tsoumani M, Ciaccio CE, Portnoy JM, Mansfield LE, Fritz SB, Lanser BJ, Matz J, Oude Elberink HNG, Varshney P, Dilly SG, Adelman DC, Burks AW. AR101 Oral Immunotherapy for Peanut Allergy. N Engl J Med. 2018 Nov 22;379(21):1991-2001. PubMed PMID: 30449234
  • Fleischer DM, Udkoff J, Borok J, Friedman A, Nicol N, Bienstock J, Lio P, Tollefson MM, Eichenfield LF. Atopic dermatitis: skin care and topical therapies. Semin Cutan Med Surg. 2017 Sep;36(3):104-110. PubMed PMID: 28895956
  • Eichenfield LF, Ahluwalia J, Davis DM, Fleischer DM, Waldman A, Spergel J. Curriculum United for Better Eczema Care: why, how, and what?. Semin Cutan Med Surg. 2017 Sep;36(3):93-94. PubMed PMID: 28895953
  • Dunn SE, Vicini JL, Glenn KC, Fleischer DM, Greenhawt MJ. The allergenicity of genetically modified foods from genetically engineered crops: A narrative and systematic review. Ann Allergy Asthma Immunol. 2017 Sep;119(3):214-222.e3. PubMed PMID: 28890018
  • Venter C, Brown T, Meyer R, Walsh J, Shah N, Nowak-Wegrzyn A, Chen TX, Fleischer DM, Heine RG, Levin M, Vieira MC, Fox AT. Better recognition, diagnosis and management of non-IgE-mediated cow's milk allergy in infancy: iMAP-an international interpretation of the MAP (Milk Allergy in Primary Care) guideline. Clin Transl Allergy. 2017;7:26. PubMed PMID: 28852472
  • Greenhawt MJ, Fleischer DM. Primary Prevention of Food Allergy. Curr Allergy Asthma Rep. 2017 Apr;17(4):26. PubMed PMID: 28421513
  • Abrams EM, Greenhawt M, Fleischer DM, Chan ES. Early Solid Food Introduction: Role in Food Allergy Prevention and Implications for Breastfeeding. J Pediatr. 2017 May;184:13-18. PubMed PMID: 28410085
  • Wang J, Fleischer DM. Should Peanut Be Banned in Schools?. J Allergy Clin Immunol Pract. 2017 Mar - Apr;5(2):290-294. PubMed PMID: 28283154
  • Fleischer DM. Life after LEAP: How to implement advice on introducing peanuts in early infancy. J Paediatr Child Health. 2017 Mar;53(S1):3-9. PubMed PMID: 28276109
  • Togias A, Cooper SF, Acebal ML, Assa'ad A, Baker JR Jr, Beck LA, Block J, Byrd-Bredbenner C, Chan ES, Eichenfield LF, Fleischer DM, Fuchs GJ 3rd, Furuta GT, Greenhawt MJ, Gupta RS, Habich M, Jones SM, Keaton K, Muraro A, Plaut M, Rosenwasser LJ, Rotrosen D, Sampson HA, Schneider LC, Sicherer SH, Sidbury R, Spergel J, Stukus DR, Venter C, Boyce JA. Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel. J Allergy Clin Immunol. 2017 Jan;139(1):29-44. PubMed PMID: 28065278
  • Bird JA, Groetch M, Allen KJ, Bock SA, Leonard S, Nowak-Wegrzyn AH, Sicherer S, Clark A, Fleischer DM, Venter C, Vickery B, Young MC. Conducting an Oral Food Challenge to Peanut in an Infant. J Allergy Clin Immunol Pract. 2017 Mar - Apr;5(2):301-311.e1. PubMed PMID: 27838326
  • Greenhawt M, Fleischer DM, Chan ES, Venter C, Stukus D, Gupta R, Spergel JM. LEAPing through the looking glass: secondary analysis of the effect of skin test size and age of introduction on peanut tolerance after early peanut introduction. Allergy. 2017 Aug;72(8):1254-1260. PubMed PMID: 27896827
  • Venter C, Fleischer DM. Diets for diagnosis and management of food allergy: The role of the dietitian in eosinophilic esophagitis in adults and children. Ann Allergy Asthma Immunol. 2016 Nov;117(5):468-471. PubMed PMID: 27592143
  • Fleischer DM, Venter C, Vandenplas Y. Hydrolyzed Formula for Every Infant?. Nestle Nutr Inst Workshop Ser. 2016;86:51-65. PubMed PMID: 27336594
  • Greenhawt M, Fleischer DM, Spergel JM. Is It Time for a Randomized Trial on Early Introduction of Milk?. J Allergy Clin Immunol Pract. 2016 May-Jun;4(3):489-90. PubMed PMID: 27157938
  • Greenhawt MJ, Fleischer DM, Atkins D, Chan ES. The Complexities of Early Peanut Introduction for the Practicing Allergist. J Allergy Clin Immunol Pract. 2016 Mar-Apr;4(2):221-5. PubMed PMID: 26968960
  • Jones SM, Burks AW, Keet C, Vickery BP, Scurlock AM, Wood RA, Liu AH, Sicherer SH, Henning AK, Lindblad RW, Dawson P, Berin C, Fleischer DM, Leung DY, Plaut M, Sampson HA. Long-term treatment with egg oral immunotherapy enhances sustained unresponsiveness that persists after cessation of therapy. J Allergy Clin Immunol. 2016 Apr;137(4):1117-27.e1-10. PubMed PMID: 26924470
  • Jones SM, Agbotounou WK, Fleischer DM, Burks AW, Pesek RD, Harris MW, Martin L, Thebault C, Ruban C, Benhamou PH. Safety of epicutaneous immunotherapy for the treatment of peanut allergy: A phase 1 study using the Viaskin patch. J Allergy Clin Immunol. 2016 Apr;137(4):1258-61.e1-10. PubMed PMID: 26920463
  • Sindher S, Fleischer DM, Spergel JM. Advances in the Treatment of Food Allergy: Sublingual and Epicutaneous Immunotherapy. Immunol Allergy Clin North Am. 2016 Feb;36(1):39-54. PubMed PMID: 26617226
  • Fleischer DM, Sampson HA. Reply. J Allergy Clin Immunol. 2016 Jan;137(1):335-6. PubMed PMID: 26589587
  • Fleischer DM, Sampson HA. Reply. J Allergy Clin Immunol. 2016 Jan;137(1):334. PubMed PMID: 26586039
  • Friedlander JA, DeBoer EM, Soden JS, Furuta GT, Menard-Katcher CD, Atkins D, Fleischer DM, Kramer RE, Deterding RR, Capocelli KE, Prager JD. Unsedated transnasal esophagoscopy for monitoring therapy in pediatric eosinophilic esophagitis. Gastrointest Endosc. 2016 Feb;83(2):299-306.e1. PubMed PMID: 26142551
  • Fleischer DM, Sampson HA. Reply. J Allergy Clin Immunol. 2015 Nov 14. [Epub ahead of print] PubMed PMID: 26589587
  • Fleischer DM, Sampson HA. Reply. J Allergy Clin Immunol. 2015 Nov 13. [Epub ahead of print] PubMed PMID: 26586039
  • Lanser BJ, Wright BL, Orgel KA, Vickery BP, Fleischer DM. Current Options for the Treatment of Food Allergy. Pediatr Clin North Am. 2015 Dec;62(6):1531-49. PubMed PMID: 26456449
  • Friedlander JA, DeBoer EM, Soden JS, Furuta GT, Menard-Katcher CD, Atkins D, Fleischer DM, Kramer RE, Deterding RR, Capocelli KE, Prager JD. Unsedated transnasal esophagoscopy for monitoring therapy in pediatric eosinophilic esophagitis. Gastrointest Endosc. 2015 Jul 2. [Epub ahead of print] PubMed PMID: 26142551
  • Fleischer DM, Sicherer S, Greenhawt M, Campbell D, Chan E, Muraro A, Halken S, Katz Y, Ebisawa M, Eichenfield L, Sampson H, Lack G, Du Toit G, Roberts G, Bahnson H, Feeney M, Hourihane J, Spergel J, Young M, As'aad A, Allen K, Prescott S, Kapur S, Saito H, Agache I, Akdis CA, Arshad H, Beyer K, Dubois A, Eigenmann P, Fernandez-Rivas M, Grimshaw K, Hoffman-Sommergruber K, Host A, Lau S, O'Mahony L, Mills C, Papadopoulos N, Venter C, Agmon-Levin N, Kessel A, Antaya R, Drolet B, Rosenwasser L. Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants. J Allergy Clin Immunol. 2015 Aug;136(2):258-61. PubMed PMID: 26100082
  • Greenhawt M, Chan ES, Fleischer DM. Peanut consumption in infants at risk for peanut allergy. N Engl J Med. 2015 May 28;372(22):2164-5. PubMed PMID: 26017832
  • Klinnert MD, McQuaid EL, Fedele DA, Faino A, Strand M, Robinson J, Atkins D, Fleischer DM, Hourihane JO, Cohen S, Fransen H. Children's Food Allergies: Development of the Food Allergy Management and Adaptation Scale. J Pediatr Psychol. 2015 Jul;40(6):572-80. PubMed PMID: 25797945
  • Burks AW, Wood RA, Jones SM, Sicherer SH, Fleischer DM, Scurlock AM, Vickery BP, Liu AH, Henning AK, Lindblad R, Dawson P, Plaut M, Sampson HA. Sublingual immunotherapy for peanut allergy: Long-term follow-up of a randomized multicenter trial. J Allergy Clin Immunol. 2015 May;135(5):1240-8.e1-3. PubMed PMID: 25656999
  • Chehade M, Aceves SS, Furuta GT, Fleischer DM. Food allergy and eosinophilic esophagitis: what do we do?. J Allergy Clin Immunol Pract. 2015 Jan-Feb;3(1):25-32. PubMed PMID: 25577614
  • Fleischer DM, Burks AW. Pitfalls in food allergy diagnosis: serum IgE testing. J Pediatr. 2015 Jan;166(1):8-10. PubMed PMID: 25449218
  • Fleischer DM, Sicherer S, Greenhawt M, Campbell D, Chan E, Muraro A, Halken S, Katz Y, Ebisawa M, Eichenfield L, Sampson H, Lack G, Du Toit G, Roberts G, Bahnson H, Feeney M, Hourihane J, Spergel J, Young M, As'aad A, Allen K, Prescott S, Kapur S, Saito H, Agache I, Akdis CA, Arshad H, Beyer K, Dubois A, Eigenmann P, Fernandez-Rivas M, Grimshaw K, Hoffman-Sommergruber K, Host A, Lau S, O'Mahony L, Mills C, Papadopoulos N, Venter C, Agmon-Levin N, Kessel A, Antaya R, Drolet B, Rosenwasser L. Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants. Ann Allergy Asthma Immunol. 2015 Aug;115(2):87-90. PubMed PMID: 26122934
  • Fleischer DM, Sicherer S, Greenhawt M, Campbell D, Chan E, Muraro A, Halken S, Katz Y, Ebisawa M, Eichenfield L, Sampson H, Lack G, Du Toit G, Roberts G, Bahnson H, Feeney M, Hourihane J, Spergel J, Young M, As'aad A, Allen K, Prescott S, Kapur S, Saito H, Agache I, Akdis CA, Arshad H, Beyer K, Dubois A, Eigenmann P, Fernandez-Rivas M, Grimshaw K, Hoffman-Sommergruber K, Host A, Lau S, O'Mahony L, Mills C, Papadopoulos N, Venter C, Agmon-Levin N, Kessel A, Antaya R, Drolet B, Rosenwasser L. Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants. Allergy. 2015 Oct;70(10):1193-5. PubMed PMID: 26148305
  • Fleischer DM, Sicherer S, Greenhawt M, Campbell D, Chan ES, Muraro A, Halken S, Katz Y, Ebisawa M, Eichenfield L, Sampson H. Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants. Allergy Asthma Clin Immunol. 2015;11(1):23. PubMed PMID: 26300927
  • Fleischer DM, Sicherer S, Greenhawt M, Campbell D, Chan ES, Muraro A, Halken S, Katz Y, Ebisawa M, Eichenfield L, Sampson H. Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants. World Allergy Organ J. 2015;8(1):27. PubMed PMID: 26312127
  • Fleischer DM, Sicherer S, Greenhawt M, Campbell D, Chan E, Muraro A, Halken S, Katz Y, Ebisawa M, Eichenfield L, Sampson H, Lack G, Du Toit G, Roberts G, Bahnson H, Feeney M, Hourihane J, Spergel J, Young M, As'aad A, Allen K, Prescott S, Kapur S, Saito H, Agache I, Akdis CA, Arshad H, Beyer K, Dubois A, Eigenmann P, Fernandez-Rivas M, Grimshaw K, Hoffman-Sommergruber K, Host A, Lau S, O'Mahony L, Mills C, Papadopoulos N, Venter C, Agmon-Levin N, Kessel A, Antaya R, Drolet B, Rosenwasser L. Consensus Communication on Early Peanut Introduction and the Prevention of Peanut Allergy in High-risk Infants. Pediatrics. 2015 Aug 31. [Epub ahead of print] PubMed PMID: 26324871
  • Fleischer DM, Sicherer S, Greenhawt M, Campbell D, Chan E, Muraro A, Halken S, Katz Y, Ebisawa M, Eichenfield L, Sampson H, Lack G, Du Toit G, Roberts G, Bahnson H, Feeney M, Hourihane J, Spergel J, Young M, As'aad A, Allen K, Prescott S, Kapur S, Saito H, Agache I, Akdis CA, Arshad H, Beyer K, Dubois A, Eigenmann P, Fernandez-Rivas M, Grimshaw K, Hoffman-Sommergruber K, Host A, Lau S, O'Mahony L, Mills C, Papadopoulos N, Venter C, Agmon-Levin N, Kessel A, Antaya R, Drolet B, Rosenwasser L. Consensus Communication on Early Peanut Introduction and Prevention of Peanut Allergy in High-Risk Infants. Pediatr Dermatol. 2015 Sep 10. [Epub ahead of print] PubMed PMID: 26354148
  • Fleischer DM, Sicherer S, Greenhawt M, Campbell D, Chan E, Muraro A, Halken S, Katz Y, Ebisawa M, Eichenfield L, Sampson H, Lack G, Du Toit G, Roberts G, Bahnson H, Feeney M, Hourihane J, Spergel J, Young M, As'aad A, Allen K, Prescott S, Kapur S, Saito H, Agache I, Akdis CA, Arshad H, Beyer K, Dubois A, Eigenmann P, Fernandez-Rivas M, Grimshaw K, Hoffman-Sommergruber K, Host A, Lau S, O'Mahony L, Mills C, Papadopoulos N, Venter C, Agmon-Levin N, Kessel A, Antaya R, Drolet B, Rosenwasser L. Consensus Communication on Early Peanut Introduction and the Prevention of Peanut Allergy in High-risk Infants. Pediatrics. 2015 Aug 31. [Epub ahead of print] PubMed PMID: 26324871
  • Kottyan LC, Davis BP, Sherrill JD, Liu K, Rochman M, Kaufman K, Weirauch MT, Vaughn S, Lazaro S, Rupert AM, Kohram M, Stucke EM, Kemme KA, Magnusen A, He H, Dexheimer P, Chehade M, Wood RA, Pesek RD, Vickery BP, Fleischer DM, Lindbad R, Sampson HA, Mukkada VA, Putnam PE, Abonia JP, Martin LJ, Harley JB, Rothenberg ME. Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease. Nat Genet. 2014 Aug;46(8):895-900. PubMed PMID: 25017104
  • Klinnert MD, Silveira L, Harris R, Moore W, Atkins D, Fleischer DM, Menard-Katcher C, Aceves S, Spergel JM, Franciosi JP, Furuta GT. Health-related quality of life over time in children with eosinophilic esophagitis and their families. J Pediatr Gastroenterol Nutr. 2014 Sep;59(3):308-16. PubMed PMID: 24897164
  • Sicherer SH, Wood RA, Vickery BP, Jones SM, Liu AH, Fleischer DM, Dawson P, Mayer L, Burks AW, Grishin A, Stablein D, Sampson HA. The natural history of egg allergy in an observational cohort. J Allergy Clin Immunol. 2014 Feb;133(2):492-9. PubMed PMID: 24636473
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Professional Memberships

  • AAAAI, Fellow
  • ACAAI, Fellow
  • EAACI, Member

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado

Specialty Information

Specialties
  • Pediatrics, Board Certification (2000, 2008)
  • Allergy and Immunology, Board Certification (2005, 2015)
Conditions & Treatments
  • Lungs and Breathing - Asthma
  • Immune System - Allergies
  • Immune System
  • Immune System - Eczema
  • Lungs and Breathing
Clinical Interests
My primary clinical interest is food allergy - from the time point of accurate diagnosis, usually at a young age, and the multidisciplinary care of the patient to include psychosocial and dietitian support, through the natural history and hopefully resolution of the allergy. I also believe in helping the patient and the family navigate the management of food allergy from the young age, through important transitions to self-care of school-age children, and then independent living with food allergy as adolescents and adults.

Care Philosophy
When caring for any patient with any medical problem, patient care should involve not just treating the condition, but how that condition affects the patient AND the family as a whole. Treating food-allergic patients requires us to do this, as food allergy affects all aspects of life and the entire family. We are fortunate that Children's Hospital Colorado provides us with the tools to take a multidisciplinary treatment approach to our patients and families, with a team of staff that includes psychosocial support, dietary management, and the most recent food allergy research. And now Children's Hospital Colorado has paired this multidisciplinary care with a state of the art Allergy and Immunology Center, featuring one of the largest food challenge and research units in the world.

Public Speaking
Yes
Food Allergy

General Information

Medical Schools:
  • MD, Emory University School of Medicine (1997)
Undergraduate Schools:
  • BA, University of Pennsylvania (Philadelphia, PA) (1992)
Internships:
  • Johns Hopkins University School of Medicine Program (1998)
Residency Programs:
  • Johns Hopkins University School of Medicine Program, Pediatrics (2000)
Fellowships:
  • Johns Hopkins University School of Medicine Program, Pediatric Allergy and Immunology (2005)
Download CV
Languages: English
Department: Pediatrics-Allergy/Immunology
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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