Tim Garrington, MD

Professor, Pediatrics-Heme/Onc and Bone Marrow Transplantation

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Medical School
  • MD, University of Florida College of Medicine (1991)
Undergraduate School
  • BS, Furman University (SC) (1985)
Internship
  • University of North Carolina at Chapel Hill Program (1992)
Residency
  • University of North Carolina at Chapel Hill Program, Pediatrics (1994)
Fellowships
  • University of Colorado, Pediatric Hematology / Oncology (2000)
Languages
English
Department
Pediatrics-Heme/Onc and Bone Marrow Transplantation

Research Interests

My research interests include the development and assessment of methods to teach residents and fellows how to deliver bad news and development and assessment of a curriculum to teach primary care providers in rural Colorado how to manage patients in their practice who are cancer survivors.

Publications

  • Brown RD, Ambler SK, Li M, Sullivan TM, Henry LN, Crossno JT Jr, Long CS, Garrington TP, Stenmark KR. MAP kinase kinase kinase-2 (MEKK2) regulates hypertrophic remodeling of the right ventricle in hypoxia-induced pulmonary hypertension. Am J Physiol Heart Circ Physiol. 2013 Jan;304(2):H269-81. PubMed PMID: 23125215
  • May LT, Wang M, Albano E, Garrington T, Dishop M, Macy ME. Undifferentiated sarcoma of the liver: a single institution experience using a uniform treatment approach. J Pediatr Hematol Oncol. 2012 Apr;34(3):e114-6. PubMed PMID: 22217489
  • Moore C and Garrington T. Clofarabine use in refractory multifocal bone Langerhans cell histiocytosis: a case report. Annual Meeting of the Histiocyte Society, October, 2012, London, UK.
  • Simko SJ, Tran HD, Jones J, Bilgi M, Beaupin LK, Coulter D, Garrington T, McCavit TL, Moore C, Rivera-Ortegón F, Shaffer L, Stork L, Turcotte L, Welsh EC, Hicks MJ, McClain KL, Allen CE. Clofarabine salvage therapy in refractory multifocal histiocytic disorders, including Langerhans cell histiocytosis, juvenile xanthogranuloma and Rosai-Dorfman disease. Pediatr Blood Cancer. 2014 Mar;61(3):479-87. PubMed PMID: 24106153
  • Brown RD, Ambler SK, Li M, Sullivan TM, Henry LN, Crossno JT Jr, Long CS, Garrington TP, Stenmark KR. MAP kinase kinase kinase-2 (MEKK2) regulates hypertrophic remodeling of the right ventricle in hypoxia-induced pulmonary hypertension. Am J Physiol Heart Circ Physiol. 2013 Jan 15;304(2):H269-81. PubMed PMID: 23125215
  • Dovel K, Scandlyn J, Whistler J, Rush SZ, and Garrington TP. The role of support groups in the well-being of pediatric hematology-oncology fellows: Perceived benefits and needed components of support groups. Annual Meeting of ASPHO, Miami, FL, April, 2013.
  • Schneider KW, and Garrington T. Renal Rhabdoid Tumor in a Pediatric Patient with Polycystic Kidney Disease. American College of Medical Genetics Annual Clinical Genetics Meeting. Nashville, TN, March, 2014.
  • Smolik S, Liu A, Garrington TP, Madden, J. Establishing a Referral and Documentation Process Between An Outpatient Oncology Setting With Offsite Radiation Oncology. Association of Pediatric Hematology/Oncology Nurse’s 37th Annual Conference and Exhibit. Louisville, KY, September 2013.
  • Acker SN, Bruny JL, Garrington TP, Partrick DA. Minimally invasive surgical techniques are safe in the diagnosis and treatment of pediatric malignancies. Surg Endosc. 2014 Aug 27. [Epub ahead of print] PubMed PMID: 25159642
  • Simko SJ, Tran HD, Jones J, Bilgi M, Beaupin LK, Coulter D, Garrington T, McCavit TL, Moore C, Rivera-Ortegón F, Shaffer L, Stork L, Turcotte L, Welsh EC, Hicks MJ, McClain KL, Allen CE. Clofarabine salvage therapy in refractory multifocal histiocytic disorders, including Langerhans cell histiocytosis, juvenile xanthogranuloma and Rosai-Dorfman disease. Pediatr Blood Cancer. 2014 Mar;61(3):479-87. PubMed PMID: 24106153
  • Carrasco A Jr, Caldwell BT, Cost CR, Greffe BS, Garrington TP, Bruny JL, Black JO, Cost NG. Reliability of intraoperative frozen section for the diagnosis of renal tumors suspicious for malignancy in children and adolescents. Pediatr Blood Cancer. 2017 Jan 18. [Epub ahead of print] PubMed PMID: 28097784
  • Amini A, Waxweiler TV, Maroni PD, Kessler ER, Cost CR, Greffe BS, Garrington TP, Liu AK, Cost NG. Survival outcomes of adolescent and adult patients with non-seminomatous testicular germ-cell tumors: A population-based study. J Pediatr Urol. 2016 Dec;12(6):405.e1-405.e9. PubMed PMID: 27544905
  • Amini A, Murphy B, Cost CR, Garrington TP, Greffe BS, Liu AK. Cardiac Mortality in Children and Adolescents with Hodgkin's Lymphoma: A Surveillance, Epidemiology and End Results Analysis. J Adolesc Young Adult Oncol. 2016 Jun;5(2):181-6. PubMed PMID: 26959398
  • Deeney S, Stewart C, Treece AL, Black JO, Lovell MA, Garrington T, Karrer F, Bruny J. Diagnostic utility of core needle biopsy versus open wedge biopsy for pediatric intraabdominal solid tumors: Results of a prospective clinical study. J Pediatr Surg. 2017 Sep 4. [Epub ahead of print] PubMed PMID: 28943139
  • Stokes W, Amini A, Maroni PD, Kessler ER, Stokes C, Cost CR, Greffe BS, Garrington TP, Liu AK, Cost NG. Patterns of care and survival outcomes for adolescent and young adult patients with testicular seminoma in the United States: A National Cancer Database analysis. J Pediatr Urol. 2017 Aug;13(4):386.e1-386.e7. PubMed PMID: 28153774
  • Carrasco A Jr, Caldwell BT, Cost CR, Greffe BS, Garrington TP, Bruny JL, Black JO, Cost NG. Reliability of intraoperative frozen section for the diagnosis of renal tumors suspicious for malignancy in children and adolescents. Pediatr Blood Cancer. 2017 Aug;64(8). PubMed PMID: 28097784
  • Amini A, Waxweiler TV, Maroni PD, Kessler ER, Cost CR, Greffe BS, Garrington TP, Liu AK, Cost NG. Survival outcomes of adolescent and adult patients with non-seminomatous testicular germ-cell tumors: A population-based study. J Pediatr Urol. 2016 Dec;12(6):405.e1-405.e9. PubMed PMID: 27544905
  • Amini A, Murphy B, Cost CR, Garrington TP, Greffe BS, Liu AK. Cardiac Mortality in Children and Adolescents with Hodgkin's Lymphoma: A Surveillance, Epidemiology and End Results Analysis. J Adolesc Young Adult Oncol. 2016 Jun;5(2):181-6. PubMed PMID: 26959398
  • Moreira DC, Macy ME, Cost CR, Greffe BS, Garrington TP. Central Nervous System Involvement of Rhabdomyosarcoma: A Single Institution Experience. J Pediatr Hematol Oncol. 2018 Apr 17. [Epub ahead of print] PubMed PMID: 29668538
  • Stokes CL, Stokes WA, Kalapurakal JA, Paulino AC, Cost NG, Cost CR, Garrington TP, Greffe BS, Roach JP, Bruny JL, Liu AK. Timing of Radiation Therapy in Pediatric Wilms Tumor: A Report From the National Cancer Database. Int J Radiat Oncol Biol Phys. 2018 Jun 1;101(2):453-461. PubMed PMID: 29559286
  • Risendal B, Westfall JM, Zittleman L, Hodgson C, Garrington T, Sutter C, Jarrell L, LeBlanc W, Overholser L. Impact of Cancer Survivorship Care Training on Rural Primary Care Practice Teams: a Mixed Methods Approach. J Cancer Educ. 2020 Sep 25. [Epub ahead of print] PubMed PMID: 32974812
  • Nellan A, Bodlak A, Mirsky DM, Mulcahy Levy J, Garrington TP, Foreman NK, Gilani A, Hayashi M. ddPCR Analysis Reveals BRAF V600E Mutations Are Infrequent in Isolated Pituitary Langerhans Cell Histiocytosis Patients. J Neuropathol Exp Neurol. 2020 Sep 15. [Epub ahead of print] PubMed PMID: 32930721
  • Koo J, Garrington TP, Kerr K, Treece AL, Cost CR. Pediatric ovarian Sertoli-Leydig cell tumors with heterologous rhabdomyosarcoma elements: Clinical case series and review of the literature. Pediatr Blood Cancer. 2020 Jul 30;:e28621. [Epub ahead of print] PubMed PMID: 32729194
  • Locatelli F, Jordan MB, Allen C, Cesaro S, Rizzari C, Rao A, Degar B, Garrington TP, Sevilla J, Putti MC, Fagioli F, Ahlmann M, Dapena Diaz JL, Henry M, De Benedetti F, Grom A, Lapeyre G, Jacqmin P, Ballabio M, de Min C. Emapalumab in Children with Primary Hemophagocytic Lymphohistiocytosis. N Engl J Med. 2020 May 7;382(19):1811-1822. PubMed PMID: 32374962
  • Friend BD, Wolfe Schneider K, Garrington T, Truscott L, Martinez-Agosto JA, Venick RS, Tsai Chambers E, Weng P, Farmer DG, Chang VY, Federman N. Is polycystic kidney disease associated with malignancy in children?. Mol Genet Genomic Med. 2019 Jul;7(7):e00725. PubMed PMID: 31197971
  • Moreira DC, Macy ME, Cost CR, Greffe BS, Garrington TP. Central Nervous System Involvement of Rhabdomyosarcoma: A Single Institution Experience. J Pediatr Hematol Oncol. 2019 Mar;41(2):152-154. PubMed PMID: 29668538
  • Rodriguez KD, Schneider KW, Suttman A, Garrington T, Jellins T, Tholen K, Francom CR, Herrmann BW. Pediatric Head and Neck Tumors Associated with Li-Fraumeni Syndrome. Ann Otol Rhinol Laryngol. 2021 May 10;:34894211014786. [Epub ahead of print] PubMed PMID: 33971750
  • Bodlak A, Chang K, Channel J, Treece AL, Donaldson N, Cost CR, Garrington TP, Greffe B, Luna-Fineman S, Sopfe J, Loeb DM, Hayashi M. Circulating Plasma Tumor DNA Is Superior to Plasma Tumor RNA Detection in Ewing Sarcoma Patients: ptDNA and ptRNA in Ewing Sarcoma. J Mol Diagn. 2021 Jul;23(7):872-881. PubMed PMID: 33887462
  • Han DS, Chalmers DJ, Greffe B, Garrington T, Partrick D, Lovell M, Schneider KW, Cost NG. A Cystic Renal Mass in the Setting of a Pneumothorax: More Than Meets the Eye?. Urology. 2021 Aug;154:275-277. PubMed PMID: 33571543
  • Rodriguez KD, Schneider KW, Suttman A, Garrington T, Jellins T, Tholen K, Francom CR, Herrmann BW. Pediatric Head and Neck Tumors Associated with Li-Fraumeni Syndrome. Ann Otol Rhinol Laryngol. 2021 May 10;:34894211014786. [Epub ahead of print] PubMed PMID: 33971750
  • Bodlak A, Chang K, Channel J, Treece AL, Donaldson N, Cost CR, Garrington TP, Greffe B, Luna-Fineman S, Sopfe J, Loeb DM, Hayashi M. Circulating Plasma Tumor DNA Is Superior to Plasma Tumor RNA Detection in Ewing Sarcoma Patients: ptDNA and ptRNA in Ewing Sarcoma. J Mol Diagn. 2021 Jul;23(7):872-881. PubMed PMID: 33887462
  • Han DS, Chalmers DJ, Greffe B, Garrington T, Partrick D, Lovell M, Schneider KW, Cost NG. A Cystic Renal Mass in the Setting of a Pneumothorax: More Than Meets the Eye?. Urology. 2021 Aug;154:275-277. PubMed PMID: 33571543
  • Risendal B, Westfall JM, Zittleman L, Hodgson C, Garrington T, Sutter C, Jarrell L, LeBlanc W, Overholser L. Impact of Cancer Survivorship Care Training on Rural Primary Care Practice Teams: a Mixed Methods Approach. J Cancer Educ. 2020 Sep 25. [Epub ahead of print] PubMed PMID: 32974812
  • Risendal B, Westfall JM, Zittleman L, Hodgson C, Garrington T, Sutter C, Jarrell L, LeBlanc W, Overholser L. Impact of Cancer Survivorship Care Training on Rural Primary Care Practice Teams: a Mixed Methods Approach. J Cancer Educ. 2022 Feb;37(1):71-80. PubMed PMID: 32974812
  • Harding E, Cho S, Garrington T, Mandell E. A Neonate Presenting with Cholestasis and Thrombocytopenia. Neoreviews. 2023 Sep 1;24(9):e583-e586. PubMed PMID: 37653080
  • Nellan A, Bodlak A, Mirsky DM, Mulcahy Levy J, Garrington TP, Foreman NK, Gilani A, Hayashi M. ddPCR Analysis Reveals BRAF V600E Mutations Are Infrequent in Isolated Pituitary Langerhans Cell Histiocytosis Patients. J Neuropathol Exp Neurol. 2020 Dec 4;79(12):1313-1319. PubMed PMID: 32930721
  • Moody KM, Andersen C, Bradley J, Draper L, Garrington T, Gill J, Harrison D, Hayashi M, Heaton A, Holladay C, Lion A, Rajan A, Rozo B, Runco D, Salvador L, Ferguson V, Arnold R. In-person and virtual adaptation of an interprofessional palliative care communications skills training course for pediatric oncology clinicians. Res Sq. 2023 Aug 11. PubMed PMID: 37609163
  • Moreira DC, Metzger ML, Antillón-Klussmann F, González-Ramella O, Gao Y, Bazzeh F, Middlekauff J, Fox Irwin L, Gonzalez ML, Chantada G, Barr RD, Garrington T, Hastings C, Kutluk T, Saab R, Khan MS, Saha V, Rodríguez-Galindo C, Friedrich P. Development of EPAT: An assessment tool for pediatric hematology/oncology training programs. Cancer. 2023 Nov 1;129(21):3448-3456. PubMed PMID: 37417913
  • Dyess NF, Weikel BW, Barker JM, Garrington TP, Parker TA. Parental leave during pediatric fellowship training: A national survey. PLoS One. 2022;17(12):e0279447. PubMed PMID: 36548290
  • Koo J, Garrington TP, Kerr K, Treece AL, Cost CR. Pediatric ovarian Sertoli-Leydig cell tumors with heterologous rhabdomyosarcoma elements: Clinical case series and review of the literature. Pediatr Blood Cancer. 2020 Oct;67(10):e28621. PubMed PMID: 32729194
  • Risendal B, Westfall JM, Zittleman L, Hodgson C, Garrington T, Sutter C, Jarrell L, LeBlanc W, Overholser L. Impact of Cancer Survivorship Care Training on Rural Primary Care Practice Teams: a Mixed Methods Approach. J Cancer Educ. 2022 Feb;37(1):71-80. PubMed PMID: 32974812
  • Locatelli F, Jordan MB, Allen C, Cesaro S, Rizzari C, Rao A, Degar B, Garrington TP, Sevilla J, Putti MC, Fagioli F, Ahlmann M, Dapena Diaz JL, Henry M, De Benedetti F, Grom A, Lapeyre G, Jacqmin P, Ballabio M, de Min C. Emapalumab in Children with Primary Hemophagocytic Lymphohistiocytosis. N Engl J Med. 2020 May 7;382(19):1811-1822. PubMed PMID: 32374962
  • Tim Garrington, Chris McKinney, Nicole Kelp, Aimee Bernard, Vijaya Knight, Tai Lockspeiser, Rachael Tan, Katie Holloman, Helen MacFarlane, Rachelle Kelchin, David Ecker. Team-based learning (TBL): a highly interactive teaching strategy successfully used in the Plains medical school curriculum. Poster presentation for CUSOM Academy of Medical Education Symposium, April, 2023. Aurora, Colorado.
  • Slatnick LR, Cost C, Garrington T, Donaldson N, Macy ME. Central Nervous System Metastases in Pediatric Patients With Ewing Sarcoma. J Pediatr Hematol Oncol. 2024 Mar 1;46(2):e180-e183. PubMed PMID: 38316140
  • Goodspeed A, Bodlak A, Duffy AB, Nelson-Taylor S, Oike N, Porfilio T, Shirai R, Walker D, Treece A, Black J, Donaldson N, Cost C, Garrington T, Greffe B, Luna-Fineman S, Demedis J, Lake J, Danis E, Verneris M, Adams DL, Hayashi M. Characterization of transcriptional heterogeneity and novel therapeutic targets using single cell RNA-sequencing of primary and circulating Ewing sarcoma cells. bioRxiv. 2024 Jun 20. PubMed PMID: 38293103
  • Harding E, Cho S, Garrington T, Mandell E. A Neonate Presenting with Cholestasis and Thrombocytopenia. Neoreviews. 2023 Sep 1;24(9):e583-e586. PubMed PMID: 37653080
  • Moody KM, Andersen C, Bradley J, Draper L, Garrington T, Gill J, Harrison D, Hayashi M, Heaton A, Holladay C, Lion A, Rajan A, Rozo B, Runco D, Salvador L, Ferguson V, Arnold R. In-person and virtual adaptation of an interprofessional palliative care communications skills training course for pediatric oncology clinicians. Res Sq. 2023 Aug 11. PubMed PMID: 37609163
  • Moreira DC, Metzger ML, Antillón-Klussmann F, González-Ramella O, Gao Y, Bazzeh F, Middlekauff J, Fox Irwin L, Gonzalez ML, Chantada G, Barr RD, Garrington T, Hastings C, Kutluk T, Saab R, Khan MS, Saha V, Rodríguez-Galindo C, Friedrich P. Development of EPAT: An assessment tool for pediatric hematology/oncology training programs. Cancer. 2023 Nov 1;129(21):3448-3456. PubMed PMID: 37417913

Professional Memberships

  • American Society of Pediatric Hematology/Oncology (ASPHO), Member
  • Association of Pediatric Program Directors (APPD), Member
  • American Association for Cancer Education (AACE), Member
  • American Academy of Pediatrics (AAP), Fellow
  • Children’s Oncology Group (COG), Member

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado

Specialty Information

Specialties
  • Pediatrics, Board Certification (1994, 2014)
  • Pediatric Hematology / Oncology, Board Certification (2000, 2008)
Conditions & Treatments
  • Blood / Lymphatic System - Blood Disorders
  • Cancers
  • Cancers - Bone Cancer
  • Cancers - Sarcoma
  • Blood / Lymphatic System
Clinical Interests
I am the leader of our solid tumor team, so my clinical work focuses on the treatment of childhood solid tumors outside of the brain and spinal cord, such as neuroblastoma, Wilms tumor, pediatric sarcomas, and many other tumor types. I have a particular interest in histiocytic disorders and am a member of the Histiocyte Society. Outside of my clinical work, I am interested in medical education. I teach at the University of Colorado School of Medicine, and I am director of our Pediatric Hematology/Oncology Fellowship Program, training the next generation of pediatric hematologist/oncologists.

Care Philosophy
Solid tumors are rare in kids and every case is unique, so treatment has to be individualized and requires a team approach. We have a big, multidisciplinary team here to address the many aspects of cancer treatment. A key additional component to that team is the family. It is essential that the family understands what is going on and participates in the decision-making process so that the priorities and goals of the patient are always kept at the forefront. I went into pediatrics because I love the refreshing innocence and optimism of children, who have their full lives ahead of them. And, I want to do everything I can to make sure that they reach their full potential. Cancer can tragically cut short the lives of young people, cheating the world of all of the good things they would have accomplished. My goal is to do everything in my power to prevent that, through cutting edge clinical science coupled with compassionate, personalized care. A diagnosis of cancer in a child is a scary thing and is likely one of the hardest things that a parent will ever have to face. That is something I strive to remember every time a new patient walks into my office. My job is not only to treat the patient’s disease but to give the family hope and to make sure they know that they have a whole team of people here to support them through their journey.

Personal Interests
Outside of medicine, I like to garden, spend time with my family, and am an avid musician.


School of Medicine

CU Anschutz
Fitzsimons Building

13001 East 17th Place

Aurora, CO 80045

303.724.5375

School
General
Students