Stephen (Steve) Dreskin, MD, PhD
Clinical Professor, Medicine-Allergy/Clinical Immunology

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Medical School:
  • MD, Emory University School of Medicine (1977)
Graduate School :
  • PhD, Emory University (1976)
Undergraduate School:
  • BA, University of Pennsylvania (Philadelphia, PA) (1971)
  • University of California (Davis) Health System Program (1978)
  • University of California (Davis) Health System Program, Internal Medicine (1980)
  • National Institutes of Health Clinical Center Program, Allergy and Immunology (1985)
Languages: English
Department: Medicine-Allergy/Clinical Immunology

Professional Titles

  • Clinical Professor of Medicine and Immunology
  • Tenured Professor of Medicine, Allergy and Immunology, Retired
  • Interim Division Head, Allergy and Clinical Immunology

Recognition & Awards

  • Top Doctor in Denver 2012-2021, 5280 Magazine (2021)
    Voted a 5280 best doctor by my peers in response to the question, "Which physician would you trust to treat you and your family?"

Research Interests

The primary effort in my laboratory is to understand interactions between IgE and peanut allergens. In addition, we are working to understand cross-allergic reactivity between peanuts and tree nuts.


  • Clinical Professor of Medicine, Allergy and Immunology (2023)
    School of Medicine, Medicine


  • Canon N, Schein CH, Braun W, Negi SS, Chen X, Kulis MD, Kim EH, Pathy V, Pozzoli M, Liu W, Dreskin SC. Alanine Scanning of the Unstructured Region of Ara h 2 and of a Related Mimotope Reveals Critical Amino Acids for IgE Binding. Mol Nutr Food Res. 2023 Nov;67(22):e2300134. PubMed PMID: 37706599
  • Warmenhoven HJM, Hulsbos L, Dreskin SC, Akkerdaas JH, Versteeg SA, van Ree R. IgE cross-inhibition between Ara h 1 and Ara h 2 is explained by complex formation of both major peanut allergens. J Allergy Clin Immunol. 2023 Aug;152(2):436-444.e6. PubMed PMID: 37028524
  • Castenmiller C, Stigler M, Kirpas ME, Versteeg S, Akkerdaas JH, Pena-Castellanos G, Blokhuis BR, Dreskin SC, Auger L, Desgagnés R, Martel C, Mirande L, Morel B, Roberge J, Stordeur V, Tropper G, Vézina LP, Gomord V, de Jong EC, Redegeld F, Shreffler WG, Aglas L, van Ree R. Plant-based enveloped Ara h 2 bioparticles display exceptional hypo-allergenicity. Clin Exp Allergy. 2023 May;53(5):577-581. PubMed PMID: 36779573
  • Foo ACY, Nesbit JB, Gipson SAY, DeRose EF, Cheng H, Hurlburt BK, Kulis MD, Kim EH, Dreskin SC, Mustafa S, Maleki SJ, Mueller GA. Structure and IgE Cross-Reactivity among Cashew, Pistachio, Walnut, and Peanut Vicilin-Buried Peptides. J Agric Food Chem. 2023 Feb 15;71(6):2990-2998. PubMed PMID: 36728846
  • Hazebrouck S, Patil SU, Guillon B, Lahood N, Dreskin SC, Adel-Patient K, Bernard H. Immunodominant conformational and linear IgE epitopes lie in a single segment of Ara h 2. J Allergy Clin Immunol. 2022. Epub 2022/02/13. doi: 10.1016/j.jaci.2021.12.796. PubMed PMID: 35150723.
  • Hazebrouck S, Canon N, Dreskin SC. The Effector Function of Allergens. Front. Allergy. 2022;3:818732. Epub 2022/04/08. doi: 10.3389/falgy.2022.818732. PubMed PMID: 35386644; PMCID: PMC8974742
  • Zimmermann N, Abonia JP, Dreskin SC, Akin C, Bolton S, Happel CS, Geller M, Larenas-Linnemann D, Nanda A, Peterson K, Wasan A, Wechsler J, Zhang S, Bernstein JA. Developing a standardized approach for assessing mast cells and eosinophils on tissue biopsies: A Work Group Report of the AAAAI Allergic Skin Diseases Committee. J Allergy Clin Immunol. 2021 Oct;148(4):964-983. PubMed PMID: 34384610
  • Schein CH, Levine CB, McLellan SLF, Negi SS, Braun W, Dreskin SC, Anaya ES, Schmidt J. Synthetic proteins for COVID-19 diagnostics. Peptides. 2021 Sep;143:170583. PubMed PMID: 34087220
  • Dreskin SC, Koppelman SJ, Andorf S, Nadeau KC, Kalra A, Braun W, Negi SS, Chen X, Schein CH. The importance of the 2S albumins for allergenicity and cross-reactivity of peanuts, tree nuts, and sesame seeds. J Allergy Clin Immunol. 2021 Apr;147(4):1154-1163. PubMed PMID: 33217410
  • van der Kleij HPM, Warmenhoven HJM, van Ree R, Versteeg SA, Pieters RHH, Dreskin SC, Knulst AC, Hoffen EV, Opstelten DJE, Koppelman SJ, Smit JJ. Chemically modified peanut extract shows increased safety while maintaining immunogenicity. Allergy. 2018 Dec 2. [Epub ahead of print] PubMed PMID: 30506686
  • Dreskin SC. Dr. Henry N. Claman. Ann Allergy Asthma Immunol. 2018 Nov;121(5):519-522. PubMed PMID: 30170028
  • Stitt JM, Dzieciatkowska M, Edwards MG, Hansen K, Hedlund G, Dreskin SC. The basophil proteome in chronic spontaneous urticaria distinguishes responders to omalizumab from non-responders. Clin Exp Allergy. 2018 Jul;48(7):898-901. PubMed PMID: 29671921
  • Chen X, Dreskin SC. Application of phage peptide display technology for the study of food allergen epitopes. Mol Nutr Food Res. 2016 Dec 20. [Epub ahead of print] PubMed PMID: 27995755
  • Moutsoglou DM, Dreskin SC. Prolonged Treatment of Peanut-Allergic Mice with Bortezomib Significantly Reduces Serum Anti-Peanut IgE but Does Not Affect Allergic Symptoms. Int Arch Allergy Immunol. 2016;170(4):257-261. PubMed PMID: 27705966
  • Dreskin SC, Halsey NA, Kelso JM, Wood RA, Hummell DS, Edwards KM, Caubet JC, Engler RJ, Gold MS, Ponvert C, Demoly P, Sanchez-Borges M, Muraro A, Li JT, Rottem M, Rosenwasser LJ. International Consensus (ICON): allergic reactions to vaccines. World Allergy Organ J. 2016 Sep 16;9(1):32. PubMed PMID: 27679682
  • Chen X, Negi SS, Liao S, Gao V, Braun W, Dreskin SC. Conformational IgE epitopes of peanut allergens Ara h 2 and Ara h 6. Clin Exp Allergy. 2016 Aug;46(8):1120-8. PubMed PMID: 27238146
  • Moutsoglou DM, Dreskin SC. B cells establish, but do not maintain, long-lived murine anti-peanut IgE(a). Clin Exp Allergy. 2016 Apr;46(4):640-53. PubMed PMID: 27021119
  • Koid AE, Chapman MD, Hamilton RG, van Ree R, Versteeg SA, Dreskin SC, Koppelman SJ, Wünschmann S. Ara h 6 complements Ara h 2 as an important marker for IgE reactivity to peanut. J Agric Food Chem. 2014 Jan 8;62(1):206-13. PubMed PMID: 24328145
  • Mills K, Lay J, Wu W, Robinette C, Kesic MJ, Dreskin SC, Peden DB, Hernandez M. Vitamin E, ?-tocopherol, diminishes ex vivo basophil response to dust mite allergen. Allergy. 2014 Apr;69(4):541-4. PubMed PMID: 24697338
  • Bernard H, Guillon B, Drumare MF, Paty E, Dreskin SC, Wal JM, Adel-Patient K, Hazebrouck S. Allergenicity of peanut component Ara h 2: Contribution of conformational versus linear hydroxyproline-containing epitopes. J Allergy Clin Immunol. 2014 Dec 4. [Epub ahead of print] PubMed PMID: 25483599
  • Leiding JW, Beakes D, Dreskin SC, Grumach A, Hide M, Reshef A, Triggiani M, Kaliner MA. Case Title: 45 year-old male with recurrent angioedema: WAO international case-based discussions. World Allergy Organ J. 2014 Jan 22;7(1):2. PubMed PMID: 24450312
  • Zhuang Y, Dreskin SC. Redefining the major peanut allergens. Immunol Res. 2013 Mar;55(1-3):125-34. PubMed PMID: 22948807
  • Chen X, Wang Q, El-Mezayen R, Zhuang Y, Dreskin SC. Ara h 2 and Ara h 6 have similar allergenic activity and are substantially redundant. Int Arch Allergy Immunol. 2013;160(3):251-8. PubMed PMID: 23075924
  • Pahud BA, Williams SE, Dekker CL, Halsey N, Larussa P, Baxter RP, Klein NP, Marchant CD, Sparks RC, Jakob K, Aukes L, Swope S, Barnett E, Lewis P, Berger M, Dreskin SC, Donofrio PD, Sejvar JJ, Slade BA, Gidudu J, Vellozzi C, Edwards KM. Clinical assessment of serious adverse events in children receiving 2009 H1N1 vaccination. Pediatr Infect Dis J. 2013 Feb;32(2):163-8. PubMed PMID: 23334340
  • Go AC, Barber GR, Dreskin SC. Implementing standardized intravenous antibiotic desensitizations among hospital inpatients. Am J Health Syst Pharm. 2013 Mar 15;70(6):540-8. PubMed PMID: 23456408
  • Stitt JM, Dreskin SC. Urticaria and autoimmunity: where are we now?. Curr Allergy Asthma Rep. 2013 Oct;13(5):555-62. PubMed PMID: 23821106
  • Halsey NA, Griffioen M, Dreskin SC, Dekker CL, Wood R, Sharma D, Jones JF, LaRussa PS, Garner J, Berger M, Proveaux T, Vellozzi C, Hypersensitivity Working Group of the Clinical Immunization Safety Assessment Network, Broder K, Setse R, Pahud B, Hrncir D, Choi H, Sparks R, Williams SE, Engler RJ, Gidudu J, Baxter R, Klein N, Edwards K, Cano M, Kelso JM. Immediate hypersensitivity reactions following monovalent 2009 pandemic influenza A (H1N1) vaccines: reports to VAERS. Vaccine. 2013 Dec 9;31(51):6107-12. PubMed PMID: 24120547
  • Koid AE, Chapman MD, Hamilton RG, Van Ree R, Versteeg SA, Dreskin SC, Koppelman SJ, Wuenschmann S. Ara h 6 Complements Ara h 2 as an Important Marker for IgE Reactivity to Peanut. J Agric Food Chem. 2013 Dec 11. [Epub ahead of print] PubMed PMID: 24328145
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Professional Memberships

  • American Academy of Allergy, Asthma and Immunology (AAAI), Fellow
  • American College of Allergy and Immunology, Fellow

Practice Locations

Hospital Affiliation
  • University of Colorado Hospital

Specialty Information

  • Internal Medicine, Board Certification (1980)
  • Allergy and Immunology, Board Certification (1983)
  • Diagnostic Laboratory Immunology, Board Certification (1990)
Clinical Interests
I am an allergist / immunologist currently retired from clinical practice.

Personal Interests
Retired from clinical practice Currently conducting clinical research: 1. IgE-allergen interactions in peanut and tree nut allergy 2. Chronic idiopathic urticaria

Public Speaking
Research: 1. IgE-allergen interactions in peanut and tree nut allergy 2. Chronic idiopathic urticaria

General Information

Medical Schools:
  • MD, Emory University School of Medicine (1977)
Graduate Schools:
  • PhD, Emory University (1976)
Undergraduate Schools:
  • BA, University of Pennsylvania (Philadelphia, PA) (1971)
  • University of California (Davis) Health System Program (1978)
Residency Programs:
  • University of California (Davis) Health System Program, Internal Medicine (1980)
  • National Institutes of Health Clinical Center Program, Allergy and Immunology (1985)
Download CV
Languages: English
Department: Medicine-Allergy/Clinical Immunology
Contact Us
CU Anschutz
Fitzsimons Building

13001 East 17th Place
Campus Box C290
Aurora, CO 80045

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