Rui Zheng-Pywell, MD

Assistant Professor, Surgery-Surgical Oncology

Faculty Photo
Medical School
  • MD, Baylor College of Medicine (2017)
Internship
  • University of Alabama Medical Center (Birmingham) Program (2018)
Residency
  • University of Alabama Medical Center (Birmingham) Program, Chief Resident, Surgery (2024)
Fellowships
  • Wake Forest University School of Medicine Program, Complex General Surgical Oncology (2026)
Languages
English, Mandarin
Department
Surgery-Surgical Oncology

Professional Titles

  • Assistant Professor of Surgery

Publications

  • Zheng-Pywell R, Shen P. Role of Genetics in Gastric Malignancy: Screening, Prevention and Treatment. Surg Clin North Am. 2026 Aug;106(4):519-531. PubMed PMID: 42419310
  • Zheng-Pywell R, Lumia SJ, Felipe HC, Gironda DJ, Miller LD, Levine EA. Next-Generation Sequencing Identifies Key Targetable Mutations in the Treatment of Appendiceal Neoplasms. Ann Surg Oncol. 2026 Sep 29. [Epub ahead of print] PubMed PMID: 42809083
  • Zheng-Pywell R, Lumia SJ, Felipe HC, Gironda DJ, Miller LD, Levine EA. ASO Visual Abstract: Next-Generation Sequencing Identifies Key Targetable Mutations in the Treatment of Appendiceal Neoplasms. Ann Surg Oncol. 2026 May 8. [Epub ahead of print] PubMed PMID: 42104035
  • Gironda DJ, Erali RA, Forsythe SD, Pullikuth AK, Zheng-Pywell R, Cummins KA, Soker S, Gui X, Levine EA, Votanopoulos KI, Miller LD. The Genomic Topography of Appendiceal Cancers: Our Current Understanding, Clinical Perspectives, and Future Directions. Cancers (Basel). 2025 Oct 9;17(19). PubMed PMID: 41097802
  • Irfan A, McElroy KE, Zheng-Pywell R, Gillis A, Reddy S, Yates C, Chen H, Rose JB. NET guidelines for white patients may not fit Asian patients. Am J Surg. 2025 Feb;240:116116. PubMed PMID: 39642797
  • Gillis A, Zheng-Pywell R, McLeod C, Wang D, Ness JM, Guenter R, Whitt J, Prolla TA, Chen H, Gonzalez ML, Rose B, Lloyd RV, Jaskula-Sztul R, Lin D. Somatostatin Receptor Type 2 and Thyroid-Stimulating Hormone Receptor Expression in Oncocytic Thyroid Neoplasms: Implications for Prognosis and Treatment. Mod Pathol. 2023 Dec;36(12):100332. PubMed PMID: 37716507
  • Guenter R, Zheng-Pywell R, Herring B, Murphy M, Foote J, Benner K, Rose JB. Preclinical safety evaluation of continuous UV-A lighting in an operative setting. PLoS One. 2023;18(11):e0291083. PubMed PMID: 37976243
  • Wang, R., Lewis, M., Zheng-Pywell, R., Julson, J., Smithson, M., & Chen, H. (2022). Using the H-index as a factor in the promotion of surgical faculty. Heliyon, 8(4), e09319.
  • Zheng-Pywell R, Lopez-Aguiar A, Fields RC, Vickers S, Yates C, Dudeja V, Chen H, Reddy S, Maithel SK, Rose JB. Are We Undertreating Black Patients with Nonfunctional Pancreatic Neuroendocrine Tumors? Critical Analysis of Current Surveillance Guidelines by Race. J Am Coll Surg. 2022 Apr 1;234(4):599-606. PubMed PMID: 35380181
  • Zheng-Pywell R, Fang A, AlKashash A, Awad S, Reddy S, Vickers S, Heslin M, Dudeja V, Chen H, Rose JB. Prognostic Impact of Tumor Size on Pancreatic Neuroendocrine Tumor Recurrence May Have Racial Variance. Pancreas. 2021 Mar 1;50(3):347-352. PubMed PMID: 33835965
  • Zheng-Pywell, R., Cherian, A. J., Enman, M., Chen, H., & Abraham, D. (2020). Carcinoembryonic antigen should be concurrently checked with calcitonin to identify distant metastases in medullary thyroid cancer. International Journal of Endocrine Oncology, 7(1), IJE27.
  • Wang R, Zheng-Pywell R, Chen HA, Bibb JA, Chen H, Rose JB. Management of Gastrointestinal Neuroendocrine Tumors. Clin Med Insights Endocrinol Diabetes. 2019;12:1179551419884058. PubMed PMID: 31695546
  • Zheng-Pywell R, Reddy S. Ampullary Cancer. Surg Clin North Am. 2019 Apr;99(2):357-367. PubMed PMID: 30846039
  • Chebaro Y, Lorenz M, Fa A, Zheng R, Gustin M. Adaptation of Candida albicans to Reactive Sulfur Species. Genetics. 2017, May;206(1):151-162.
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Professional Memberships

  • Society of Surgical Oncology, Member
  • American College of Surgery, Associate Fellow

Practice Locations

UCHealth Surgical Clinic - Anschutz Medical Campus
1635 Aurora Ct
6th Floor
Aurora, CO 80045
720-848-2700

Center Affiliations

Specialty Information

Specialties
  • Complex General Surgical Oncology
  • Surgery, Board Certification (2025)
Clinical Interests
My practice focuses on the treatment of advanced GI malignancies with focus on peritoneal surface malignancies using cytoreduction and heated intraperitoneal chemotherapy (CRS/HIPEC). I am versed in the management of rare malignancies including appendiceal tumors and peritoneal mesothelioma.

Care Philosophy
I strive to be a resource and source of support for patients during their treatment journey. I believe in transparency and open communication when building a patient-physician relationship that allows for reliable and consistent care of the patient and their family througout the treatment process.