Mitchell Hayes, MD

Professional Titles

• Assistant Professor of Urology

Research Interests

Publications

• Avasthi KK, Yim KH, Kim Y, Echevarria PMR, Darst LM, Abreu N, Zea KP, Hayes MT, Vosoughi A, Manley BJ, Wang L. Multiplex RT-PCR-Based Sequencing Assay to Detect Kidney Cancer-Specific Splice Variants in Tumor Tissues and Plasma Cell-Free RNAs. Mol Diagn Ther. 2026 Sep;30(5):821-832. PubMed PMID: 42410176
• Ward KR, Hayes M, Peres LC, Fridley BL, Eschrich S, Soupir AC. FastPCA: An R package for fast singular value decomposition. J Open Source Softw. 2026;11(119). PubMed PMID: 41937916
• Sandberg M, Vancavage R, Marie-Costa C, Ye E, Hayes M, Miller J, Ben David R, Patel K, Waggener K, Aljabi B, Byun S, García Marchiñena P, Mourao T, Peyton C, Mehrazin R, Spiess P, Zanotti R, Chang S, Zequi SC, Abreu D, Rodriguez A. A comparison of renal cell carcinoma with tumor thrombus across North America, Central/South America, and South Korea. Arch Ital Urol Androl. 2025 Jun 30;97(2):13820. PubMed PMID: 40491291
• Guske C, Immen N, Conant D, Laborde J, Linscott J, Hayes M, Jazayeri SB, Fazili A, Siegel E, Dessureault S, Sanchez J, Stefanou A, Manley B, Felder S. Short- and Intermediate-Term Morbidity Following Total Pelvic Exenteration in Colorectal Cancer. Cancer Control. 2025 Jan-Dec;32:10732748251316598. PubMed PMID: 39848249
• Sandberg M, Russell G, Feldman D, Hayes M, David RB, Miller J, Patel K, Aljabi B, Byun SS, Faba OR, Cannoletta D, Letowski T, Villoldo G, Marchinena PG, Mourao T, Ciancio G, Peyton CC, Zanotti R, Chang S, Spiess PE, Mehrazin R, Abreu D, Zequi SC, Rodriguez A. Impact of Systemic Therapy for Renal Cell Carcinoma With a Tumor Thrombus: Results From the Intercontinental Collaboration on Renal Cell Carcinoma Database. Clin Genitourin Cancer. 2025 Dec;23(6):102442. PubMed PMID: 41125506
• May AM, Kadomoto S, Williams C, Soupir AC, The S, McGue JJ, Robinson T, Shelley G, Hayes MT, Fridley BL, Balasi JA, Ramos Echevarria PM, Dhillon J, Nallandhighal S, Acharyya S, Chen L, Aldous J, Schurman N, Baladandayuthapani V, Frankel TL, Salami SS, Manley BJ, Mehra R, Udager AM, Keller ET. Spatial analysis reveals a novel inflammatory tumor transition state which promotes a macrophage-driven induction of sarcomatoid renal cell carcinoma. bioRxiv [Preprint]. 2025 Jun 14:2025.06.12.656421. doi: 10.1101/2025.06.12.656421. PMID: 40661608; PMCID: PMC12259133.
• Hayes MT, Laborde J, Soupir A, Berglund A, Teer TK, Sabitov K, Chakiryan NH, Peak TC, Nguyen J, Moran-Segura C, Saeed-Vafa D, Lopez-Blanco N, Molgora M, Ramos-Echevarria, Guske C, Balasi J, Dhillon J, Kim Y, Mule J, Fridley BL, Manley BJ. Spatial Clustering of Immunosuppressive Macrophages in Papillary Renal Cell Carcinoma. Kidney Cancer. 2025;9:24-34. doi:10.1177/24684562251358595
• Sandberg M, Namugosa M, Ritts R, Costa CM, Temple D, Hayes M, Whitman W, Ye E, Refugia J, Ben-David R, Alerasool P, Eilender B, Zanotti RR, Mourão TC, Kim JK, Marchiñena PG, Byun SS, Abreu D, Mehrazin R, Spiess P, de Cassio Zequi S, Rodriguez A. The role of preoperative immune cell metrics in renal cell carcinoma with a tumor thrombus. Urologia. 2024 Aug;91(3):477-485. PubMed PMID: 38661082
• Hayes M, Yu Y, Bassale S, Chakiryan N, Chen Y, Ye S, Garzotto M, Kopp R. Calibrated Regression Models Based on the Risk of Clinical Nodal Metastasis Should be Used as Decision Aids for Prostate Cancer Staging to Reduce Unnecessary Imaging. Clin Genitourin Cancer. 2022 Dec;20(6):e490-e497. PubMed PMID: 35649886
• Hayes M, Bassale S, Chakiryan N, Boileu L, Grassauer J, Wagner M, Foster B, Coakley F, Isharwal I, Amling CL, Liu JJ. Selecting patients for magnetic resonance imaging cognitive versus ultrasound fusion biopsy of the prostate: A within-patient comparison. BJUI Compass. 2022 June 5. https://doi.org/10.1002/bco2.172
• Jiang DD, Hayes M, Gillis KA, Korets R, Wagner AA, Hedges JC, Chakiryan NH. Misaligned Incentives in Benign Prostatic Enlargement Surgery: More Complex and Efficacious Procedures Are Earning Fewer Relative Value Units. J Endourol. 2021 Jun;35(6):835-839. PubMed PMID: 33222524
• Hayes M, Schlundt D, Bonnet K, Vogus TJ, Kripalani S, Froehler MT, Ward MJ. Tales from the Trips: A Qualitative Study of Timely Recognition, Treatment, and Transfer of Emergency Department Patients with Acute Ischemic Stroke. J Stroke Cerebrovasc Dis. 2019 May;28(5):1219-1228. PubMed PMID: 30745000
• Alvarado MD, Conolly J, Park C, Sakata T, Mohan AJ, Harrison BL, Hayes M, Esserman LJ, Ozanne EM. Patient preferences regarding intraoperative versus external beam radiotherapy following breast-conserving surgery. Breast Cancer Res Treat. 2014 Jan;143(1):135-40. PubMed PMID: 24292868
• Esserman L, Hayes M, Alvarado M. Haste makes waste, but lack of urgency is opportunity lost. Breast Cancer Res Treat. 2014 Aug;147(1):223-4. PubMed PMID: 25062705

Practice Locations

• University of Colorado Hospital

• University of Colorado Cancer Center

Specialty Information

• Urology
• Society of Urologic Oncology Fellowship, Specialized Training (2025)

• Cancers - Urologic Cancer
• Cancers
• Cancers - Bladder Cancer
• Cancers - Kidney Cancer
• Cancers - Testicular Cancer
• Histology
• Kidneys and Urinary System
• Failed Prior Surgery
• Surgery - Complex Abdominal/Open Surgery
• Surgery
• Surgery - Robotic Surgery
• Surgery - Urologic Surgery
• Radiology - Abdominal Imaging
• Radiology