1. Jalan M*, Brambati A*, Shah H*, McDermott N*, Patel J, Zhu Y, Doymaz A, Wu J, Anderson KS, Gazzo A, Pareja F, Yamaguchi TN, Vougiouklakis T, Ahmed-Seghir S, Steinberg P, Neiman-Golden A, Azeroglu B, Gomez-Aguilar J, da Silva EM, Hussain S, Higginson D, Boutros PC, Riaz N, Reis-Filho JS, Powell SN, Sfeir A. RNA transcripts serve as a template for double-strand break repair in human cells. Nat Commun. 2025 May 10;16(1):4349. doi: 10.1038/s41467-025-59510-x. PMID: 40348775; PMCID: PMC12065846.
Brambati A, Sacco O, Porcella S, Heyza J, Kareh M, Schmidt JC, Sfeir A. RHINO directs MMEJ to repair DNA breaks in mitosis. Science. 2023 Aug 11;381(6658):653-660. PubMed PMID: 37440612
Chandramouly G, Zhao J, McDevitt S, Rusanov T, Hoang T, Borisonnik N, Treddinick T, Lopezcolorado FW, Kent T, Siddique LA, Mallon J, Huhn J, Shoda Z, Kashkina E, Brambati A, Stark JM, Chen XS, Pomerantz RT. Pol? reverse transcribes RNA and promotes RNA-templated DNA repair. Sci Adv. 2021 Jun;7(24). PubMed PMID: 34117057
Zardoni L, Nardini E, Brambati A, Lucca C, Choudhary R, Loperfido F, Sabbioneda S, Liberi G. Elongating RNA polymerase II and RNA:DNA hybrids hinder fork progression and gene expression at sites of head-on replication-transcription collisions. Nucleic Acids Res. 2021 Dec 16;49(22):12769-12784. PubMed PMID: 34878142
Rawal CC, Zardoni L, Di Terlizzi M, Galati E, Brambati A, Lazzaro F, Liberi G, Pellicioli A. Senataxin Ortholog Sen1 Limits DNA:RNA Hybrid Accumulation at DNA Double-Strand Breaks to Control End Resection and Repair Fidelity. Cell Rep. 2020 May 5;31(5):107603. PubMed PMID: 32375052
Brambati A, Barry RM, Sfeir A. DNA polymerase theta (Pol?) - an error-prone polymerase necessary for genome stability. Curr Opin Genet Dev. 2020 Feb;60:119-126. PubMed PMID: 32302896
Brambati A, Zardoni L, Nardini E, Pellicioli A, Liberi G. The dark side of RNA:DNA hybrids. Mutat Res Rev Mutat Res. 2020 Apr-Jun;784:108300. PubMed PMID: 32430097
Brambati A, Zardoni L, Achar YJ, Piccini D, Galanti L, Colosio A, Foiani M, Liberi G. Dormant origins and fork protection mechanisms rescue sister forks arrested by transcription. Nucleic Acids Res. 2018 Feb 16;46(3):1227-1239. PubMed PMID: 29059325
Alzu A, Bermejo R, Begnis M, Lucca C, Piccini D, Carotenuto W, Saponaro M, Brambati A, Cocito A, Foiani M, Liberi G. Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes. Cell. 2012 Nov 9;151(4):835-846. PubMed PMID: 23141540
