Andrea Sikora, PharmD

Professional Titles

• Associate Professor

Research Interests

My research centers upon the vision that all critically ill patients receive data-driven comprehensive medication management. In particular, I am interested in the development and implementation of artificial intelligence (AI) to improve clinical decision-making for medication management, including structuring medication data pipelines for interoperability, methods development for handling high-dimensional medication data, and implementation that connects AI-driven insights to clinicians at the bedside to improve patient-centered outcomes. I am also interested in how to improve the meaningfulness of scientific discovery through team science and mentorship network and am the author of two books on these topics, Pay It Forward: A Map to Mentorship in Medicine and InteGREAT: How to make great healthcare teams.

Publications

• Sikora A. Mapping the next steps for critical care pharmacists. Am J Health Syst Pharm. 2024 Sep 9;81(18):783-784. PubMed PMID: 38995094
• Alanazi AH, Almuntashiri S, Sikora A, Zhang D, Somanath PR. Secondary Analysis of Fluids and Catheters Treatment Trial (FACTT) data reveal poor clinical outcomes in acute respiratory distress syndrome patients with diabetes. Respir Med. 2024 Mar;223:107540. PubMed PMID: 38290602
• Anthony Hawkins W, Darley A, Malcom DR, Smith SE, Sikora A, Bland CM, Hixon LM, Flowers G, Branan TN. Design and implementation considerations of experiential interprofessional share days for a new practitioner. Am J Health Syst Pharm. 2024 Jan 1;81(1):e12-e17. PubMed PMID: 37772433
• Rafiei A, Ghiasi Rad M, Sikora A, Kamaleswaran R. Improving mixed-integer temporal modeling by generating synthetic data using conditional generative adversarial networks: A case study of fluid overload prediction in the intensive care unit. Comput Biol Med. 2024 Jan;168:107749. PubMed PMID: 38011778
• Smith SE, Sikora AN, Fulford M, Rogers KC. Long-Term Retention of Advanced Cardiovascular Life Support Knowledge and Confidence in Doctor of Pharmacy Students. Am J Pharm Educ. 2024 Jan;88(1):100609. PubMed PMID: 37866521
• Branan TN, Hawkins WA, Palmer R, Sikora A, Huntt K, Phillips BB, Clemmons AB, Bland CM, Smith SE. Translating Clinical Decision-Making Skills From a Critical Care Pharmacy Elective to the Required Curriculum. Am J Pharm Educ. 2024 Jan;88(1):100599. PubMed PMID: 37806556
• Chase AM, Forehand CC, Keats KR, Taylor AN, Jones TW, Sikora A. Evaluation of Critical Care Pharmacist Evening Services at an Academic Medical Center. Hosp Pharm. 2024 Apr;59(2):228-233. PubMed PMID: 38450349
• Forehand C, Keats K, Amerine LB, Sikora A. Rethinking justifications for critical care pharmacist positions: Translating bedside evidence to the C-suite. Am J Health Syst Pharm. 2023 Sep 7;80(18):1275-1279. PubMed PMID: 37254868
• Alexander PMA, Aslakson RA, Barreto EF, Lee JH, Meissen H, Morrow BM, Nazer L, Branson RD, Mayer KP, Napolitano N, Lane-Fall MB, Sikora A, John PR, Dellinger RP, Parker M, Argent A, Boateng A, Green TP, Kudchadkar SR, Maslove DM, Rech MA, Sorce LR, Tasker RC, Buchman TG, Checchia PA. The Reviewer Academy of the Society of Critical Care Medicine: Key Principles and Strategic Plan. Crit Care Med. 2023 Sep 1;51(9):1111-1123. PubMed PMID: 37341529
• Ha L, Sikora A. Clinician-Designed Dashboards. Hosp Pharm. 2023 Jun;58(3):225-226. PubMed PMID: 37216076
• Sikora A. Critical Care Pharmacists: A Focus on Horizons. Crit Care Clin. 2023 Jul;39(3):503-527. PubMed PMID: 37230553
• Almuntashiri S, Chase A, Sikora A, Zhang D. The Potential Synergistic Risk of Albuterol and Vasoactives in Acute Lung Injury Trials. Ann Pharmacother. 2023 Jul;57(7):757-761. PubMed PMID: 36189647
• Baker L, Logan LD, Brooks K, Sikora A. Responding to racism, discrimination, and microaggressions: A student-designed case-based learning program. Am J Health Syst Pharm. 2023 Jan 24;80(3):98-101. PubMed PMID: 36269036
• Chase AM, Azimi HA, Forehand CC, Keats K, Taylor A, Wu S, Blotske K, Sikora A. An Evaluation of the Relationship Between Medication Regimen Complexity as Measured by the MRC-ICU to Medication Errors in Critically Ill Patients. Hosp Pharm. 2023 Dec;58(6):569-574. PubMed PMID: 38560536
• Azimi H, Johnson L, Loudermilk C, Chase A, Forehand CC, Sikora A. Medication regimen complexity (MRC-ICU) for in-hospital mortality prediction in COVID-19 patients. Hosp Pharm. 2023 Dec;58(6):564-568. PubMed PMID: 38550708
• Chase AM, Wayne NB, Sikora A. Standardizing Lower Heparin Concentrations for Use in Anticoagulation of Percutaneous Left Ventricular Assist Device (pVAD) D5W Purge Solutions. J Pharm Pract. 2023 Aug;36(4):739-740. PubMed PMID: 35235757
• Sulejmani E, Sikora A, Hawkins WA. Teaching at the critically ill patient's bedside: Linking clinical practice to professional identity. Am J Health Syst Pharm. 2023 Apr 8;80(8):537-540. PubMed PMID: 36680793
• Kandaswamy S, Dawson TE, Moore WH, Howell K, Beus J, Adu O, Sikora A. Pharmacist Metrics in the Pediatric Intensive Care Unit: an Exploration of the Medication Regimen Complexity-Intensive Care Unit (MRC-ICU) Score. J Pediatr Pharmacol Ther. 2023;28(8):728-734. PubMed PMID: 38094672
• Almuntashiri S, Zhang D, Somanath PR, Sikora A. MMP3 in Severe COVID-19: A Biomarker or Therapeutic Target?. Infect Disord Drug Targets. 2023;23(1):e190622206159. PubMed PMID: 35726419
• Sikora A, Ayyala D, Rech MA, Blackwell SB, Campbell J, Caylor MM, Condeni MS, DePriest A, Dzierba AL, Flannery AH, Hamilton LA, Heavner MS, Horng M, Lam J, Liang E, Montero J, Murphy D, Plewa-Rusiecki AM, Sacco AJ, Sacha GL, Shah P, Smith MP, Smith Z, Radosevich JJ, Vilella AL. Impact of Pharmacists to Improve Patient Care in the Critically Ill: A Large Multicenter Analysis Using Meaningful Metrics With the Medication Regimen Complexity-ICU (MRC-ICU) Score. Crit Care Med. 2022 Sep 1;50(9):1318-1328. PubMed PMID: 35678204
• Almuntashiri S, Han Y, Youngblood HA, Chase A, Zhu Y, Wang X, Linder DF, Siddiqui B, Sikora A, Liu Y, Zhang D. Identification of circulating microvesicle-encapsulated miR-223 as a potential novel biomarker for ARDS. Physiol Rep. 2022 Nov;10(21):e15494. PubMed PMID: 36353917
• Sikora A, Martin GS. Critical Care Pharmacists: Improving Care by Increasing Access to Medication Expertise. Ann Am Thorac Soc. 2022 Nov;19(11):1796-1798. PubMed PMID: 35976863
• Smith SE, Murray B, Sikora A. Response to Haas et al. Am J Health Syst Pharm. 2022 Jun 23;79(13):1041-1042. PubMed PMID: 35230386
• Smith SE, Shelley R, Sikora A. Medication regimen complexity vs patient acuity for predicting critical care pharmacist interventions. Am J Health Syst Pharm. 2022 Apr 1;79(8):651-655. PubMed PMID: 34864850
• Murray B, Sikora A. Teaching the pursuit of sustainable excellence. Am J Health Syst Pharm. 2022 Aug 19;79(17):1406-1409. PubMed PMID: 35670475
• Jones S, Ly W, Murray B, Sikora A. Team science, layered learning, and mentorship networks: The trifecta for maximizing scholastic achievement for clinical pharmacists. Am J Health Syst Pharm. 2022 Dec 5;79(24):2271-2278. PubMed PMID: 36087297
• Sikora A, Murray B. Addressing Matters of Life and Death in the Pharmacy Curriculum. Am J Pharm Educ. 2022 Jun;86(5):8636. PubMed PMID: 34301571
• Carr JR, Hawkins WA, Newsome AS, Smith SE, Amber B C, Bland CM, Branan TN. Fluid Stewardship of Maintenance Intravenous Fluids. J Pharm Pract. 2022 Oct;35(5):769-782. PubMed PMID: 33827313
• Webb AJ, Rowe S, Newsome AS. A descriptive report of the rapid implementation of automated MRC-ICU calculations in the EMR of an academic medical center. Am J Health Syst Pharm. 2022 Jun 7;79(12):979-983. PubMed PMID: 35187576
• Hawkins WA, Kim JY, Smith SE, Sikora Newsome A, Hall RG. Effects of Propofol on Hemodynamic Profile in Adults Receiving Targeted Temperature Management. Hosp Pharm. 2022 Jun;57(3):329-335. PubMed PMID: 35615480
• Murray B, Newsome AS. Avoiding cost avoidance. Am J Health Syst Pharm. 2022 Jan 5;79(2):14-15. PubMed PMID: 34487144
• Taylor A, Jones T, Forehand CC, Smith SE, Dykes H, Newsome AS. Vasopressor Discontinuation Order in Septic Shock With Reduced Left Ventricular Function. J Pharm Pract. 2022 Dec;35(6):879-885. PubMed PMID: 33977793
• Olney WJ, Chase AM, Hannah SA, Smith SE, Newsome AS. Medication Regimen Complexity Score as an Indicator of Fluid Balance in Critically Ill Patients. J Pharm Pract. 2022 Aug;35(4):573-579. PubMed PMID: 33685269
• Forehand CC, Fitton K, Keats K, Chase A, Smith SE, Sikora Newsome A. Productivity Tracking: A Survey of Critical Care Pharmacist Practices and Satisfaction. Hosp Pharm. 2022 Apr;57(2):273-280. PubMed PMID: 35601725
• Gamble KC, Smith SE, Bland CM, Sikora Newsome A, Branan TN, Hawkins WA. Hidden Fluids in Plain Sight: Identifying Intravenous Medication Classes as Contributors to Intensive Care Unit Fluid Intake. Hosp Pharm. 2022 Apr;57(2):230-236. PubMed PMID: 35601708

Professional Memberships

• Society of Critical Care Medicine, Fellow
• American College of Clinical Pharmacy, Fellow