Josephine Harrington, MD

Publications

• Piccini JP, Patel MR, Steffel J, Ferdinand K, Van Gelder IC, Russo AM, Ma CS, Goodman SG, Oldgren J, Hammett C, Lopes RD, Akao M, De Caterina R, Kirchhof P, Gorog DA, Hemels M, Rienstra M, Jones WS, Harrington J, Lip GYH, Ellis SJ, Rockhold FW, Neumann C, Alexander JH, Viethen T, Hung J, Coppolecchia R, Mundl H, Caso V. Asundexian versus Apixaban in Patients with Atrial Fibrillation. N Engl J Med. 2025 Jan 2;392(1):23-32. PubMed PMID: 39225267
• Chang AJ, Liang Y, Girouard MP, Bhatt AS, Sandhu AT, Sauer AJ, Greene SJ, Harrington J, Go AS, Ambrosy AP. Changing the paradigm in heart failure: shifting from treatment to prevention. Heart Fail Rev. 2025 Jan;30(1):177-189. PubMed PMID: 39441333
• Nouhravesh N, Harrington J, Aberle LH, Green CL, Voss K, Holdsworth D, Misialek K, Slaugh BT, Wieand M, Yancy WS Jr, Pagidipati N, Mentz RJ. Effects of fortified eggs and time-restricted eating on cardiometabolic health: The prosperity trial. Am Heart J. 2025 Jan;279:27-39. PubMed PMID: 39414223
• Harrington J, McGuire DK, Inzucchi SE. Sodium-Glucose Cotransporter 2 Inhibitors and Glucagon-Like Peptide 1 Receptor Agonists: A One-Two Punch?. JACC Heart Fail. 2024 Nov;12(11):1827-1829. PubMed PMID: 39387772
• Haller PM, Jarolim P, Palazzolo MG, Bellavia A, Antman EM, Eikelboom J, Granger CB, Harrington J, Healey JS, Hijazi Z, Patel MR, Patel SM, Ruff CT, Wallentin L, Braunwald E, Giugliano RP, Morrow DA. Heart Failure Risk Assessment Using Biomarkers in Patients With Atrial Fibrillation: Analysis From COMBINE-AF. J Am Coll Cardiol. 2024 Oct 15;84(16):1528-1540. PubMed PMID: 39230543
• Harrington J, Kang YM, McGuire DK. Is This the Real Life? Real-World Evidence of Empagliflozin in Health Care Resource Utilization and Cost. Diabetes Care. 2024 Nov 1;47(11):1897-1899. PubMed PMID: 39432776
• Petrie MC, Udell JA, Anker SD, Harrington J, Jones WS, Mattheus M, Gasior T, van der Meer P, Amir O, Bahit MC, Bauersachs J, Bayes-Genis A, Chopra VK, Januzzi JL, Lopes RD, Ponikowski P, Rossello X, Schou M, Zieroth S, Brueckmann M, Sumin M, Bhatt DL, Hernandez AF, Butler J. Empagliflozin in acute myocardial infarction in patients with and without type 2 diabetes: A pre-specified analysis of the EMPACT-MI trial. Eur J Heart Fail. 2024 Dec 26. [Epub ahead of print] PubMed PMID: 39725521
• Harrington J, Leyva M, Rao VN, Oakes M, Osude N, Bosworth HB, Pagidipati NJ. Implementing guideline-directed medical therapy: Stakeholder-identified barriers and facilitators. Am Heart J. 2024 Nov 28;281:23-31. [Epub ahead of print] PubMed PMID: 39613172
• Reed SD, Harrington JL, Morin DP, Saba SF, Montgomery JA, Harrison RW, Frisch DR, Viethen T, Tamm M, Xiao J, Mundl H, Coppolecchia R, Yang JC, Wallace MJ, Gonzalez JM, Patel MR. Participant Engagement and Preference Study for Clinical Outcomes Associated With Atrial Fibrillation: The PEARL-AF Study. JACC Adv. 2024 Dec;3(12):101370. PubMed PMID: 39568653
• Halaseh R, Sauer AJ, Vardeny O, Canonico ME, Harrington J, Svetlichnaya J, Ambrosy AP. A fine addition: Finerenone in the evolving landscape of heart failure with preserved ejection fraction. Heart Fail Rev. 2024 Oct 30. [Epub ahead of print] PubMed PMID: 39476221
• Harrington J, Gale SE, Vest AR. Anti-Obesity Medications in Patients With Heart Failure: Current Evidence and Practical Guidance. Circ Heart Fail. 2024 Sep;17(9):e011518. PubMed PMID: 39087359
• Karpurapu A, Williams HA, DeBenedittis P, Baker CE, Ren S, Thomas MC, Beard AJ, Devlin GW, Harrington J, Parker LE, Smith AK, Mainsah B, Pla MM, Asokan A, Bowles DE, Iversen E, Collins L, Karra R. Deep Learning Resolves Myovascular Dynamics in the Failing Human Heart. JACC Basic Transl Sci. 2024 May;9(5):674-686. PubMed PMID: 38984052
• Harrington J. Anti-obesity medications in the management of heart failure with preserved ejection fraction: available evidence and next STEPS. Heart Fail Rev. 2024 Sep;29(5):939-944. PubMed PMID: 38965119
• Nouhravesh N, Garg J, Rockhold FW, De Pasquale CG, O'Meara E, Lewis GD, Butler J, Harrington J, Ezekowitz JA, Ponikowski P, Troughton RW, Wong YW, Blackman N, Numan S, Adamczyk R, Hernandez AF, Mentz RJ. Characterization of serum phosphate levels over time with intravenous ferric carboxymaltose versus placebo as treatment for heart failure with reduced ejection fraction and iron deficiency: An exploratory prospective substudy from HEART-FID. Eur J Heart Fail. 2024 Jun 19. [Epub ahead of print] PubMed PMID: 38896006
• Harrington J. STEP HFpEF DM: a sweet sequel. Heart Fail Rev. 2024 Sep;29(5):913-915. PubMed PMID: 38888653
• Medina CK, Barnes SG, Felker GM, Mentz RJ, Pagidipati NJ, Seymour KA, Schroder JN, Harrington J. Severe obesity among patients with left ventricular assist devices. Am Heart J. 2024 Aug;274:130-133. PubMed PMID: 38866442
• Harrington J, Hellkamp AS, Mahaffey KW, Breithardt G, Halperin JL, Hankey GJ, Becker RC, Nessel CC, Berkowitz SD, Fox KAA, Singer DE, Goodman SG, Patel MR, Piccini JP. Assessment of Days Alive Out of Hospital as a Possible End Point in Trials of Stroke Prevention for Atrial Fibrillation: A ROCKET AF Analysis. J Am Heart Assoc. 2024 Jun 4;13(11):e028951. PubMed PMID: 38780169
• Peters AE, Clare RM, Chiswell K, Harrington J, Kelsey A, Hernandez A, Felker GM, Mentz RJ, DeVore AD. Implications of trial eligibility in patients with heart failure with mildly reduced or preserved ejection fraction. ESC Heart Fail. 2024 Oct;11(5):2813-2824. PubMed PMID: 38757437
• Greene SJ, Chambers R, Lerman JB, Harrington J, deFilippi CR, Wendell DC, Kim HW, Green CL, Butler J, Felker GM. Sacubitril/valsartan and cardiovascular biomarkers among patients with recent COVID-19 infection: The PARACOR-19 randomized clinical trial. Eur J Heart Fail. 2024 Jun;26(6):1393-1398. PubMed PMID: 38733160
• Harrington J, Felker GM, Lingvay I, Pagidipati NJ, Pandey A, McGuire DK. Managing Obesity in Heart Failure: A Chance to Tip the Scales?. JACC Heart Fail. 2024 Jan;12(1):28-34. PubMed PMID: 37897462
• Harrington J, Rao VN, Leyva M, Oakes M, Mentz RJ, Bosworth HB, Pagidipati NJ. Improving Guideline-Directed Medical Therapy for Patients With Heart Failure With Reduced Ejection Fraction: A Review of Implementation Strategies. J Card Fail. 2024 Feb;30(2):376-390. PubMed PMID: 38142886
• Harrington J, Mentz RJ, Rockhold FW, Garg J, Butler J, De Pasquale CG, Ezekowitz JA, Lewis GD, O'Meara E, Ponikowski P, Troughton RW, Wong YW, Adamczyk R, Storie T, Blackman N, Hernandez AF. Hierarchical End Points in Prior Heart Failure Trials and the HEART-FID Trial. Circ Heart Fail. 2024 Feb;17(2):e010676. PubMed PMID: 38250799
• Harrington J, Felker GM, Januzzi JL, Lam CSP, Lingvay I, Pagidipati NJ, Sattar N, Van Spall HGC, Verma S, McGuire DK. Worth Their Weight? An Update on New and Emerging Pharmacologic Agents for Obesity and Their Potential Role for Persons with Cardiac Conditions. Curr Cardiol Rep. 2024 Mar;26(3):61-71. PubMed PMID: 38551786
• Sattar N, Butler J, Lee MMY, Harrington J, Sharma A, Zannad F, Filippatos G, Verma S, Januzzi JL, Ferreira JP, Pocock SJ, Pfarr E, Ofstad AP, Brueckmann M, Packer M, Anker SD. Body mass index and cardiorenal outcomes in the EMPEROR-Preserved trial: Principal findings and meta-analysis with the DELIVER trial. Eur J Heart Fail. 2024 Apr;26(4):900-909. PubMed PMID: 38558521
• Hernandez AF, Udell JA, Jones WS, Anker SD, Petrie MC, Harrington J, Mattheus M, Seide S, Zwiener I, Amir O, Bahit MC, Bauersachs J, Bayes-Genis A, Chen Y, Chopra VK, A Figtree G, Ge J, G Goodman S, Gotcheva N, Goto S, Gasior T, Jamal W, Januzzi JL, Jeong MH, Lopatin Y, Lopes RD, Merkely B, Parikh PB, Parkhomenko A, Ponikowski P, Rossello X, Schou M, Simic D, Steg PG, Szachniewicz J, van der Meer P, Vinereanu D, Zieroth S, Brueckmann M, Sumin M, Bhatt DL, Butler J. Effect of Empagliflozin on Heart Failure Outcomes After Acute Myocardial Infarction: Insights From the EMPACT-MI Trial. Circulation. 2024 May 21;149(21):1627-1638. PubMed PMID: 38581389
• Butler J, Jones WS, Udell JA, Anker SD, Petrie MC, Harrington J, Mattheus M, Zwiener I, Amir O, Bahit MC, Bauersachs J, Bayes-Genis A, Chen Y, Chopra VK, Figtree G, Ge J, Goodman SG, Gotcheva N, Goto S, Gasior T, Jamal W, Januzzi JL, Jeong MH, Lopatin Y, Lopes RD, Merkely B, Parikh PB, Parkhomenko A, Ponikowski P, Rossello X, Schou M, Simic D, Steg PG, Szachniewicz J, van der Meer P, Vinereanu D, Zieroth S, Brueckmann M, Sumin M, Bhatt DL, Hernandez AF. Empagliflozin after Acute Myocardial Infarction. N Engl J Med. 2024 Apr 25;390(16):1455-1466. PubMed PMID: 38587237
• Udell JA, Petrie MC, Jones WS, Anker SD, Harrington J, Mattheus M, Seide S, Amir O, Bahit MC, Bauersachs J, Bayes-Genis A, Chen Y, Chopra VK, Figtree G, Ge J, Goodman SG, Gotcheva N, Goto S, Gasior T, Jamal W, Januzzi JL, Jeong MH, Lopatin Y, Lopes RD, Merkely B, Martinez-Traba M, Parikh PB, Parkhomenko A, Ponikowski P, Rossello X, Schou M, Simic D, Steg PG, Szachniewicz J, van der Meer P, Vinereanu D, Zieroth S, Brueckmann M, Sumin M, Bhatt DL, Hernandez AF, Butler J. Left Ventricular Function, Congestion, and Effect of Empagliflozin on Heart Failure Risk After Myocardial Infarction. J Am Coll Cardiol. 2024 Jun 11;83(23):2233-2246. PubMed PMID: 38588929
• Harrington J, Sattar N, Felker GM, Januzzi JL, Lam CSP, Pagidipati NJ, Pandey A, Van Spall HGC, McGuire DK. Putting More Weight on Obesity Trials in Heart Failure. Curr Heart Fail Rep. 2024 Jun;21(3):194-202. PubMed PMID: 38619690
• Harrington J, McCrary AW, Nguyen M, Nyandiko W, Barker PCA, Koech M, Thielman NM, Muehlbauer MJ, Shah SH, Bloomfield GS. Proteomics discovery in children and young adults with HIV identifies fibrosis, inflammatory, and immune biomarkers associated with myocardial impairment. AIDS. 2024 Jun 1;38(7):1090-1093. PubMed PMID: 38691053

Practice Locations

UCHealth Heart & Vascular Center - Anschutz
12505 E. 16th Ave
Anschutz Inpatient Pavilion 2, 3rd floor
Aurora, CO 80045
720-848-5300

Specialty Information

Specialties

• Cardiology