Jonathan Irish, PhD

Publications

• Froese JT, Balsamo JA, Reisman BJ, Barone SM, Irish JM, Bachmann BO. Multiplexed activity metabolomics for isolation of filipin macrolides from a hypogean actinomycete. J Antibiot (Tokyo). 2024 Dec 6. [Epub ahead of print] PubMed PMID: 39643649
• Syrimi E, Khan N, Murray P, Willcox C, Haigh T, Willcox B, Masand N, Bowen C, Dimakou DB, Zuo J, Barone SM, Irish JM, Kearns P, Taylor GS. Defects in NK cell immunity of pediatric cancer patients revealed by deep immune profiling. iScience. 2024 Sep 20;27(9):110837. PubMed PMID: 39310750
• Voss K, Bartkowiak T, Sewell AE, Chi C, Landis MD, Schaefer S, Pua HH, Connelly JA, Irish JM, Rathmell JC, Kaviany S. Peripheral T Cell Development and Immunophenotyping of Twins with Heterozygous FOXN1 Mutations. Immunohorizons. 2024 Jul 1;8(7):492-499. PubMed PMID: 39008056
• Thirman HL, Hayes MJ, Brown LE, Porco JA Jr, Irish JM. Single Cell Profiling Distinguishes Leukemia-Selective Chemotypes. bioRxiv. 2024 May 3. PubMed PMID: 38826485
• Tentori CA, Zhao LP, Tinterri B, Strange KE, Zoldan K, Dimopoulos K, Feng X, Riva E, Lim B, Simoni Y, Murthy V, Hayes MJ, Poloni A, Padron E, Cardoso BA, Cross M, Winter S, Santaolalla A, Patel BA, Groarke EM, Wiseman DH, Jones K, Jamieson L, Manogaran C, Daver N, Gallur L, Ingram W, Ferrell PB, Sockel K, Dulphy N, Chapuis N, Kubasch AS, Olsnes AM, Kulasekararaj A, De Lavellade H, Kern W, Van Hemelrijck M, Bonnet D, Westers TM, Freeman S, Oelschlaegel U, Valcarcel D, Raddi MG, Grønbæk K, Fontenay M, Loghavi S, Santini V, Almeida AM, Irish JM, Sallman DA, Young NS, van de Loosdrecht AA, Adès L, Della Porta MG, Cargo C, Platzbecker U, Kordasti S. Immune-monitoring of myelodysplastic neoplasms: Recommendations from the i4MDS consortium. Hemasphere. 2024 May;8(5):e64. PubMed PMID: 38756352
• Cross CE, Mayeda C, Medina S, Hayes MJ, Kaviany S, Connelly JA, Rathmell JC, Weaver KD, Thompson RC, Chambless LB, Ihrie RA, Irish JM. Velociraptor: Cross-Platform Quantitative Search Using Hallmark Cell Features. bioRxiv. 2024 May 4. PubMed PMID: 38746337
• Canderan G, Muehling LM, Kadl A, Ladd S, Bonham C, Cross CE, Lima SM, Yin X, Sturek JM, Wilson JM, Keshavarz B, Bryant N, Murphy DD, Cheon IS, McNamara CA, Sun J, Utz PJ, Dolatshahi S, Irish JM, Woodfolk JA. Distinct Type 1 Immune Networks Underlie the Severity of Restrictive Lung Disease after COVID-19. bioRxiv. 2024 Apr 4. PubMed PMID: 38617217
• Medina S, Brockman AA, Cross CE, Hayes MJ, Mobley BC, Mistry AM, Chotai S, Weaver KD, Thompson RC, Chambless LB, Ihrie RA, Irish JM. IL-8 Instructs Macrophage Identity in Lateral Ventricle Contacting Glioblastoma. bioRxiv. 2024 Mar 30. PubMed PMID: 38585888
• von Lersner AK, Fernandes F, Ozawa PMM, Jackson M, Masureel M, Ho H, Lima SM, Vagner T, Sung BH, Wehbe M, Franze K, Pua H, Wilson JT, Irish JM, Weaver AM, Di Vizio D, Zijlstra A. Multiparametric Single-Vesicle Flow Cytometry Resolves Extracellular Vesicle Heterogeneity and Reveals Selective Regulation of Biogenesis and Cargo Distribution. ACS Nano. 2024 Apr 16;18(15):10464-10484. PubMed PMID: 38578701
• Bewersdorf JP, Shallis RM, Sharon E, Park S, Ramaswamy R, Roe CE, Irish JM, Caldwell A, Wei W, Yacoub A, Madanat YF, Zeidner JF, Altman JK, Odenike O, Yerrabothala S, Kovacsovics T, Podoltsev NA, Halene S, Little RF, Piekarz R, Gore SD, Kim TK, Zeidan AM. A multicenter phase Ib trial of the histone deacetylase inhibitor entinostat in combination with pembrolizumab in patients with myelodysplastic syndromes/neoplasms or acute myeloid leukemia refractory to hypomethylating agents. Ann Hematol. 2024 Jan;103(1):105-116. PubMed PMID: 38036712
• Norlander AE, Abney M, Cephus JY, Roe CE, Irish JM, Shelburne NJ, Newcomb DC, Hemnes AR, Peebles RS Jr. Reply to Yasuma et al. Am J Respir Crit Care Med. 2023 Dec 1;208(11):1249-1250. PubMed PMID: 37774400
• Senosain MF, Zou Y, Patel K, Zhao S, Coullomb A, Rowe DJ, Lehman JM, Irish JM, Maldonado F, Kammer MN, Pancaldi V, Lopez CF. Integrated Multi-omics Analysis of Early Lung Adenocarcinoma Links Tumor Biological Features with Predicted Indolence or Aggressiveness. Cancer Res Commun. 2023 Jul;3(7):1350-1365. PubMed PMID: 37501683
• Norlander AE, Abney M, Cephus JY, Roe CE, Irish JM, Shelburne NJ, Newcomb DC, Hemnes AR, Peebles RS Jr. Prostaglandin I(2) Therapy Promotes Regulatory T Cell Generation in Patients with Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2023 Sep 15;208(6):737-739. PubMed PMID: 37413696
• Bartkowiak T, Lima SM, Hayes MJ, Mistry AM, Brockman AA, Sinnaeve J, Leelatian N, Roe CE, Mobley BC, Chotai S, Weaver KD, Thompson RC, Chambless LB, Ihrie RA, Irish JM. An immunosuppressed microenvironment distinguishes lateral ventricle-contacting glioblastomas. JCI Insight. 2023 Jun 22;8(12). PubMed PMID: 37192001
• Alexander MR, Dale BL, Smart CD, Elijovich F, Wogsland CE, Lima SM, Irish JM, Madhur MS. Immune Profiling Reveals Decreases in Circulating Regulatory and Exhausted T Cells in Human Hypertension. JACC Basic Transl Sci. 2023 Mar;8(3):319-336. PubMed PMID: 37034287
• Geben LC, Brockman AA, Chalkley MBL, Sweet SR, Gallagher JE, Scheuing AL, Simerly RB, Ess KC, Irish JM, Ihrie RA. Dephosphorylation of 4EBP1/2 Induces Prenatal Neural Stem Cell Quiescence. bioRxiv. 2023 Feb 15. PubMed PMID: 36824760
• Brockman AA, Khurana R, Bartkowiak T, Thomas PL, Sivagnanam S, Betts CB, Coussens LM, Lovly CM, Irish JM, Ihrie RA. Alignment, segmentation and neighborhood analysis in cyclic immunohistochemistry data using CASSATT. Cytometry B Clin Cytom. 2023 Sep;104(5):344-355. PubMed PMID: 36748312
• Medina S, Ihrie RA, Irish JM. Learning cell identity in immunology, neuroscience, and cancer. Semin Immunopathol. 2023 Jan;45(1):3-16. PubMed PMID: 36534139