Mario Enrico Canonico, PhD

Assistant Research Professor, Medicine-Cardiology

Faculty Photo
Department
Medicine-Cardiology

Publications

  • Forzano I, Florimonte D, Narciso V, Canonico ME, Castiello DS, Manzi L, Cristiano S, Spinelli A, Vallone DM, D'Alconzo D, Semplice F, Paolillo R, Giugliano G, Cesaro A, Gragnano F, Calabrò P, Esposito G, Gargiulo G. Optimal Medical Therapy Targeting Lipids and Inflammation for Secondary Prevention in Patients Undergoing Percutaneous Coronary Intervention. J Clin Med. 2025 Nov 24;14(23). PubMed PMID: 41375637
  • Skowronski J, Hosseini K, Bruno J, Sakata Y, Nodari S, Keramida K, Cedarbaum ER, Canonico ME, Palazzuoli A, Kato E. Dapagliflozin in acute heart failure: lessons from the DAPA ACT HF-TIMI 68 trial. Heart Fail Rev. 2025 Dec 8;31(1):10. PubMed PMID: 41354894
  • Piccolo R, Laino A, Vitale AP, Canonico ME, Avvedimento M, Simonetti F, Paolillo R, Piaz FD, Charlier B, Spinelli A, Cristiano S, Serafino LD, Cirillo P, Gargiulo G, Franzone A, Filippelli A, Conti V, Esposito G. Sex differences among elderly ACS patients undergoing percutaneous coronary intervention receiving Ticagrelor 60 mg vs. 90 mg. J Thromb Thrombolysis. 2025 Nov 16. [Epub ahead of print] PubMed PMID: 41243071
  • Canonico ME, Kavousi M. Fatal Coronary Atherosclerosis in the Young: Rethinking Systemic Disease Paradigms?. Eur J Prev Cardiol. 2025 Nov 10. [Epub ahead of print] PubMed PMID: 41212871
  • Aboyans V, Canonico ME, Chastaingt L, Anand SS, Brodmann M, Couffinhal T, Criqui MH, Debus ES, Mazzolai L, McDermott MM, Bonaca MP. Peripheral artery disease. Nat Rev Dis Primers. 2025 Sep 18;11(1):68. PubMed PMID: 40968271
  • Basile C, Merolla A, Mancusi C, De Luca C, Fucile I, Canonico ME, Giugliano G, Orso F, Morisco C, Esposito G. Effect of Incretin-Based Therapies on Blood Pressure: A Systematic Review and Meta-Analysis. Eur J Prev Cardiol. 2025 Sep 3. [Epub ahead of print] PubMed PMID: 40899050
  • Harrington JL, Canonico ME, El Rafei A, Solomon SD, Teerlink JR, Vaduganathan M, Zieroth SR, Bonaca MP, Sauer AJ. Nonsteroidal and Steroidal Mineralocorticoid Antagonists: Rationale, Evidence, and Unanswered Questions. JACC Heart Fail. 2025 Oct;13(10):102637. PubMed PMID: 40886449
  • Basile C, Samsky MD, El Rafei A, Harrington J, Ambrosy AP, Maggioni AP, Bonaca MP, Canonico ME. Mobile integrated health for heart failure: insights from the MIGHTy-Heart trial. Heart Fail Rev. 2025 Dec;30(6):1371-1375. PubMed PMID: 40853421
  • Canonico ME, Hsia J, Chiu ST, Tseng PK, Mudd JO, Remick JD, Patel B, Chuang YH, Gluckman TJ, Bonaca MP. Temporal shift in prevalence of heart failure diagnoses and comorbidities within 2 US integrated health systems. Am J Manag Care. 2025 Aug 1;31(8):e238-e240. PubMed PMID: 40829099
  • Canonico ME, Hsia J, Masoudi FA, Bosworth HB, Greene S, Batch BC, Hamilton N, de Araujo TB, Jackson M, Broussard M, Gooden Z, Guthrie NL, Hansell B, Matteliano-Madu L, Mosesso K, Berman MA, Bonaca MP. Digital Therapeutic Based Randomized Investigation to Improve Glycemic Control in Patients With Type 2 Diabetes and Residual Hyperglycemia on Stable Medical Therapy: Rationale, Design, and Baseline Characteristics of the BRIGHT Trial. J Am Heart Assoc. 2025 Aug 5;14(15):e038737. PubMed PMID: 40673521
  • Muscoli S, Cimmino G, Canonico ME, Cesaro A, De Rosa G, De Rosa S, Coronelli MM, Natale F, Perrone MA, Sticchi A, Sorrentino S, Sucato V, Renda G, Paolillo S, Indolfi C, Calabrò P, Perrone Filardi P, Cirillo P. Comprehensive insights into peripheral artery disease: an overview from the working groups of pathogenesis of atherosclerosis and thrombosis of the Italian Society of Cardiology. J Cardiovasc Med (Hagerstown). 2025 Jul 1;26(7):325-338. PubMed PMID: 40590724
  • Rafei AE, Harrington JA, Tavares CAM, Guimarães PO, Ambrosy AP, Bonaca MP, Sauer AJ, Vardeny O, Canonico ME. Heart failure with preserved ejection fraction therapeutics: in search of the pillars. Heart Fail Rev. 2025 Sep;30(5):1005-1014. PubMed PMID: 40399553
  • Gargiulo G, Cirillo P, Sperandeo L, Castiello DS, Manzi L, Forzano I, Florimonte D, Simonetti F, Canonico ME, Avvedimento M, Paolillo R, Spinelli A, Buongiorno F, Serafino LD, Spaccarotella CAM, Franzone A, Piccolo R, Stabile E, Valgimigli M, Esposito G. Pharmacodynamic effects of cangrelor in patients with acute or chronic coronary syndrome undergoing percutaneous coronary intervention: the POMPEII Registry. EuroIntervention. 2025 May 16;21(10):560-570. PubMed PMID: 40375762
  • Biegus J, Ponikowska B, Canonico ME, Damman K, Palazzuoli A, Ambrosy AP. Bumetanide nasal spray: a novel approach to enhancing diuretic response and advancing ambulatory heart failure care?. Heart Fail Rev. 2025 Sep;30(5):1123-1126. PubMed PMID: 40360832
  • Hogan SE, Canonico ME, King RW, Low Wang CC, Nehler MR, Parr J, Rogers RK, Lu W, Albanese J, Barnathan ES, Spyropoulos AC, Douketis JD, Bonaca MP, Capell WH. Preserving Trial Endpoint Specificity and Cause of Death Attribution in Cardiovascular Trials: Insights From MARINER. JACC Adv. 2025 Jun;4(6 Pt 1):101763. PubMed PMID: 40359642
  • Canonico ME, Hess CN, Naveh S, Rogers RK, Nehler MR, Hogan SE, Hsia JA, Berkowitz SD, Bonaca MP. Prescription of aspirin plus low-dose rivaroxaban in patients with peripheral artery disease after lower-extremity revascularization. Vasc Med. 2025 Jun;30(3):318-320. PubMed PMID: 40305186
  • Gupta P, Bast JA, Razavi AC, Canonico ME, Shahzad A, Naeem M, Bonaca MP, Sperling LS, Quintana RA. Hypertension in atherosclerotic cardiovascular disease: insights into epidemiology, management strategies, and outcomes. Curr Opin Cardiol. 2025 Jul 1;40(4):206-212. PubMed PMID: 40305167
  • Castiello DS, Buongiorno F, Manzi L, Narciso V, Forzano I, Florimonte D, Sperandeo L, Canonico ME, Avvedimento M, Paolillo R, Spinelli A, Cristiano S, Simonetti F, Semplice F, D'Alconzo D, Vallone DM, Giugliano G, Sciahbasi A, Cirillo P, Gragnano F, Calabrò P, Esposito G, Gargiulo G. Procedural and Antithrombotic Therapy Optimization in Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention: A Narrative Review. J Cardiovasc Dev Dis. 2025 Apr 8;12(4). PubMed PMID: 40278201
  • Canonico ME, Avvedimento M, Piccolo R, Hess CN, Bardi L, Ilardi F, Giugliano G, Franzone A, Gargiulo G, Berkowitz SD, Cannon CP, Esposito G, Bonaca MP. Long-term Antithrombotic Therapy in Patients With Chronic Coronary Syndrome: An Updated Review of Current Evidence. Clin Ther. 2025 Jul;47(7):511-518. PubMed PMID: 40229176
  • Basile C, Rodolico D, Villaschi A, Canonico ME, Fucile I, Giugliano G, Mancusi C, Morisco C, Esposito G. Time-to-first clinical benefit in heart failure with preserved ejection fraction: a reconstructed time-to-event meta-analysis of randomized controlled trials. Eur J Prev Cardiol. 2025 Aug 25;32(11):1018-1020. PubMed PMID: 40200554
  • Manzi L, Buongiorno F, Narciso V, Florimonte D, Forzano I, Castiello DS, Sperandeo L, Paolillo R, Verde N, Spinelli A, Cristiano S, Avvedimento M, Canonico ME, Bardi L, Giugliano G, Gargiulo G. Acute Heart Failure and Non-Ischemic Cardiomyopathies: A Comprehensive Review and Critical Appraisal. Diagnostics (Basel). 2025 Feb 23;15(5). PubMed PMID: 40075788
  • Canonico ME, Bauersachs R, Bonaca MP. Reply: Where the Definition of Fragility Came From and Where It Will Go. J Am Coll Cardiol. 2025 Jan 28;85(3):e45-e46. PubMed PMID: 39843038
  • Canonico ME, Ambrosy AP, Samsky MD. Lessons learned and future perspectives from the PRO-HF trial. Heart Fail Rev. 2025 May;30(3):525-527. PubMed PMID: 39794682
  • Halaseh R, Sauer AJ, Vardeny O, Canonico ME, Harrington J, Svetlichnaya J, Ambrosy AP. A fine addition: Finerenone in the evolving landscape of heart failure with preserved ejection fraction. Heart Fail Rev. 2025 Mar;30(2):287-291. PubMed PMID: 39476221
  • Gluckman TJ, Chiu ST, Rider D, Tseng PK, Mudd JO, Remick JD, Granowitz C, Carroll A, Sikirica S, Canonico ME, Hsia J, Bonaca MP. Relationship Between Left Ventricular Ejection Fraction and ICD-10 Codes Among Patients Hospitalized With Heart Failure. Clin Cardiol. 2024 Dec;47(12):e70055. PubMed PMID: 39686565
  • Halaseh R, Sauer AJ, Vardeny O, Canonico ME, Harrington J, Svetlichnaya J, Ambrosy AP. A fine addition: Finerenone in the evolving landscape of heart failure with preserved ejection fraction. Heart Fail Rev. 2024 Oct 30. [Epub ahead of print] PubMed PMID: 39476221
  • Canonico ME, Hess CN, Secemsky EA, Bonaca MP. Antithrombotic Therapy in Patients Undergoing Peripheral Artery Interventions. Interv Cardiol Clin. 2024 Oct;13(4):553-559. PubMed PMID: 39245554
  • Canonico ME, Low Wang CC, Hsia J, Debus ES, Nehler MR, Patel MR, Anand SS, Ycas J, Capell WH, Muehlhofer E, Haskell LP, Berkowitz SD, Bauersachs R, Bonaca MP. Low-Dose Rivaroxaban Plus Aspirin in Fragile Patients After Lower Extremity Revascularization. J Am Coll Cardiol. 2024 Aug 27;84(9):801-811. PubMed PMID: 39168566
  • Canonico ME, Verde N, Avvedimento M, Leone A, Cutillo M, Simonetti F, Esposito S, Bardi L, Giugliano G, Stabile E, Piccolo R, Esposito G. Safety and Efficacy of Combined Coronary and Peripheral Percutaneous Revascularization: A Proof-of-Concept Study. J Clin Med. 2024 Aug 2;13(15). PubMed PMID: 39124782
  • Nardi E, Santoro C, Prastaro M, Canonico ME, Paolillo S, Gargiulo G, Gargiulo P, Parlati ALM, Basile C, Bardi L, Giuliano M, Esposito G. Crosslink between atrial fibrillation and cancer: a therapeutic conundrum. Cardiooncology. 2024 Aug 7;10(1):48. PubMed PMID: 39113118
  • Piccolo R, Simonetti F, Avvedimento M, Cutillo M, Canonico ME, Conti V, Gargiulo G, Paolillo R, Dal Piaz F, Filippelli A, Charlier B, Spinelli A, Cristiano S, Cirillo P, Di Serafino L, Franzone A, Esposito G. Ticagrelor 60 vs. 90 mg in elderly ACS patients undergoing PCI: a randomized, crossover trial. Eur Heart J Cardiovasc Pharmacother. 2024 Nov 6;10(7):578-587. PubMed PMID: 39025785
  • Morrison JT, Canonico ME, Anand SS, Patel MR, Debus ES, Nehler MR, Hess CN, Hsia J, Capell WH, Muehlhofer E, Haskell LP, Berkowitz SD, Bauersachs RM, Bonaca MP. Low-Dose Rivaroxaban Plus Aspirin in Patients With Peripheral Artery Disease Undergoing Lower Extremity Revascularization With and Without Concomitant Coronary Artery Disease: Insights From VOYAGER PAD. Circulation. 2024 May 7;149(19):1536-1539. PubMed PMID: 38709838
  • Canonico ME, Hess CN, Rogers RK, Bonaca MP. Medical Therapy for Peripheral Artery Disease. Curr Cardiol Rep. 2024 Jun;26(6):651-659. PubMed PMID: 38696099
  • Gupta P, Canonico ME, Faaborg-Andersen C, Prabhu N, Kondapalli L, Quintana RA. Updates in the management of cancer therapy-related hypertension. Curr Opin Cardiol. 2024 Jul 1;39(4):235-243. PubMed PMID: 38391284
View All (34 Total) View Less

School of Medicine

CU Anschutz

Fitzsimons Building

13001 East 17th Place

Campus Box C290

Aurora, CO 80045


303.724.5375