John Janetzko, PhD

Assistant Professor, Biochemistry & Molecular Genetics

Publications

  • Karafin MS, Issaian AV, Bevers S, Reisz JA, Hay A, Keele GR, Dzieciatkowska M, Cendali FI, Haiman ZB, Key AM, Nemkov T, Stephenson D, Marsh E, Moore AL, Palha MS, Legenzov EA, Lamb DR, Deng X, Stone M, Hansen KC, Kleinman S, Norris PJ, Busch MP, Vallese F, Palsson BO, Spitalnik SL, Kao JPY, Roubinian NH, Janetzko J, Page GP, Eisenmesser EZ, Zimring JC, Buehler PW, D'Alessandro A. Genetic variation of human G6PD impacts Red Blood Cell transfusion efficacy. bioRxiv. 2025 Nov 22. PubMed PMID: 41332617
  • Janetzko J, Perry-Hauser NA. Emerging voices in G protein-coupled receptor biology. Mol Pharmacol. 2025 Nov;107(11):100083. PubMed PMID: 41167027
  • Deutsch J, Hilger D, Janetzko J, Schroeder CM, Chu S, Kobilka BK, Shivnaraine RV. Ligand-dependent G protein dynamics underlying opioid signaling efficacy. bioRxiv. 2025 Jul 5. PubMed PMID: 40631176
  • Palo MZ, Ha B, Lapointe CP, Alvarado C, Janetzko J, Carette JE, Puglisi JD, Puglisi EV. Conserved long-range interactions are required for stable folding of orthoflaviviral genomic RNA. Nucleic Acids Res. 2025 Jun 6;53(11). PubMed PMID: 40521663
  • Janetzko J, Deutsch J, Shi Y, Siepe DH, Masureel M, Liu W, Viner R, Inoue A, Chu S, Kobilka BK, Shivnaraine RV. Membrane phosphoinositides allosterically tune ß-arrestin dynamics to facilitate GPCR core engagement. bioRxiv. 2025 Jul 23. PubMed PMID: 40501946
  • Ives AN, Jooß K, Melani RD, Fellers RT, Janetzko J, Kelleher NL. Capillary Zone Electrophoresis-Mass Spectrometry of Intact G Protein-Coupled Receptors Enables Proteoform Profiling. Anal Chem. 2025 Apr 8;97(13):7307-7316. PubMed PMID: 40146057
  • R Sayana, J Xu, K Callon, J Deutsch, J Zou, J Janetzko… - ICML 2025 Generative AI and Biology (GenBio)
  • Pacheco J, Peña KA, Savransky S, Gidon A, Hammond GRV, Janetzko J, Vilardaga JP. Fast-diffusing receptor collisions with slow-diffusing peptide ligand assemble the ternary parathyroid hormone-GPCR-arrestin complex. Nat Commun. 2024 Dec 3;15(1):10499. PubMed PMID: 39627206
  • Potter SC, Gibbs BE, Hammel FA, Joiner CM, Paulo JA, Janetzko J, Levine ZG, Fei GQ, Haggarty SJ, Walker S. Dissecting OGT's TPR domain to identify determinants of cellular function. Proc Natl Acad Sci U S A. 2024 May 28;121(22):e2401729121. PubMed PMID: 38768345
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School of Medicine

CU Anschutz

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Aurora, CO 80045


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