Alfredo Ornelas Sanchez, PhD

Publications

• Ornelas A, Countess JA, Kim JY, Colgan SP. Modifying microbially derived short chain fatty acids to promote health. J Physiol. 2026 Jan;604(1):116-128. PubMed PMID: 40460326
• Ornelas A, Countess JA, Kim JY, Cohen RH, Gomez BD, Roer RL, Minhajuddin F, Yenugudhati Vijaya Sai K, Zhou L, Dunn JLM, Reigan P, Cartwright IM, Hall CHT, Bhagavatula G, Onyiah JC, Dowdell AS, Colgan SP. Metabolite mimicry identifies butyrate analogs with select protective functions in the intestinal mucosa. bioRxiv. 2026 Jan 8. PubMed PMID: 41542554
• Ornelas A, Welch N, Countess JA, Zhou L, Wang RX, Dowdell AS, Colgan SP. Mimicry of microbially-derived butyrate reveals templates for potent intestinal epithelial HIF stabilizers. Gut Microbes. 2023 Dec;15(2):2267706. PubMed PMID: 37822087
• Seymour BJ, Trent B, Allen BE, Berlinberg AJ, Tangchittsumran J, Jubair WK, Chriswell ME, Liu S, Ornelas A, Stahly A, Alexeev EE, Dowdell AS, Sneed SL, Fechtner S, Kofonow JM, Robertson CE, Dillon SM, Wilson CC, Anthony RM, Frank DN, Colgan SP, Kuhn KA. Microbiota-dependent indole production stimulates the development of collagen-induced arthritis in mice. J Clin Invest. 2023 Dec 19;134(4). PubMed PMID: 38113112