Steven Thorpe, MD, FACS

Professional Titles

• Chief, Musculoskeletal Oncology

Research Interests

Publications

• Priester JI, Simister SK, Sario M, Choi J, Pina D, Theriault R, Bateni C, Ghasemiesfe A, Carr-Ascher J, Monjazeb AM, Canter RJ, Randall RL, Thorpe SW. Scrutinizing the use of contrasted chest CTs in extremity sarcoma staging and surveillance. J Surg Oncol. 2024 Mar;129(3):523-530. PubMed PMID: 37997294
• Walker K, Simister SK, Carr-Ascher J, Monument MJ, Thorpe SW, Randall RL. Emerging innovations and advancements in the treatment of extremity and truncal soft tissue sarcomas. J Surg Oncol. 2024 Jan;129(1):97-111. PubMed PMID: 38010997
• Spierenburg G, Staals EL, Palmerini E, Randall RL, Thorpe SW, Wunder JS, Ferguson PC, Verspoor FGM, Houdek MT, Bernthal NM, Schreuder BHWB, Gelderblom H, van de Sande MAJ, van der Heijden L. Active surveillance of diffuse-type tenosynovial giant cell tumors: A retrospective, multicenter cohort study. Eur J Surg Oncol. 2024 Feb;50(2):107953. PubMed PMID: 38215550
• Griffin KH, Thorpe SW, Sebastian A, Hum NR, Coonan TP, Sagheb IS, Loots GG, Randall RL, Leach JK. Engineered bone marrow as a clinically relevant ex vivo model for primary bone cancer research and drug screening. Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2302101120. PubMed PMID: 37729195
• Randall RL, Theriault RV, Thorpe SW, Monument MJ. Emerging innovations and advancements in the field of musculoskeletal oncology. J Surg Oncol. 2023 Sep;128(3):415-417. PubMed PMID: 37537986
• Jawad MU, Theriault RV, Thorpe SW, Randall RL. Socioeconomic disparities in musculoskeletal oncology. J Surg Oncol. 2023 Sep;128(3):425-429. PubMed PMID: 37537984
• Perry LM, Cruz SM, Kleber KT, Judge SJ, Darrow MA, Jones LB, Basmaci UN, Joshi N, Settles ML, Durbin-Johnson BP, Gingrich AA, Monjazeb AM, Carr-Ascher J, Thorpe SW, Murphy WJ, Eisen JA, Canter RJ. Human soft tissue sarcomas harbor an intratumoral viral microbiome which is linked with natural killer cell infiltrate and prognosis. J Immunother Cancer. 2023 Jan;11(1). PubMed PMID: 36599469
• Jawad MU, Pollock BH, Wise BL, Zeitlinger LN, O' Donnell EF, Carr-Ascher JR, Cizik A, Ferrell B, Thorpe SW, Randall RL. Socioeconomic and insurance-related disparities in disease-specific survival among patients with metastatic bone disease. J Surg Oncol. 2023 Jan;127(1):159-173. PubMed PMID: 36121418
• Tanaka KS, Andaya VR, Thorpe SW, Gundle KR, Hayden JB, Duong YC, Avedian RS, Mohler DG, Morse LJ, Zimel MN, O'Donnell RJ, Fang A, Randall RL, Tran TH, New C, Wustrack RL. Survival and failure modes of the Compress® spindle and expandable distal femur endoprosthesis among pediatric patients: A multi-institutional study. J Surg Oncol. 2023 Jan;127(1):148-158. PubMed PMID: 36112398
• Jawad MU, Pollock BH, Zeitlinger LN, O'Donnell EF 3rd, Traven SA, Carr-Ascher JR, Alvarez E, Malogolowkin MH, Thorpe SW, Randall RL. Impact of local treatment modality on overall- and disease-specific survival for nonmetastatic pelvic and sacral Ewing sarcoma. J Surg Oncol. 2022 Sep;126(3):577-587. PubMed PMID: 35585834
• Jawad MU, Pollock BH, Alvarez E, Carr-Ascher JR, Randall RL, Thorpe SW. Correction to: Non-Private Health Insurance Predicts Advanced Stage at Presentation and Amputation in Lower Extremity High Grade Bone Sarcoma: A National Cancer Database Study. Ann Surg Oncol. 2022 Oct;29(11):7134. PubMed PMID: 35428962
• Jawad MU, Pollock BH, Randall RL, Thorpe SW. Letter to Editor Referring to the Editorial by Istl et al. 'Good Bone Structure: A Call for Stronger Design and Methodology in Disparity Studies in Orthopedic Oncology' Discussing the Published Article: 'Non-Private Health Insurance Predicts Advanced Stage at Presentation and Amputation in Lower-Extremity High-Grade Bone Sarcoma: A National Cancer Database Study'. Ann Surg Oncol. 2022 Nov;29(12):7351-7352. PubMed PMID: 35876922
• Jawad MU, Pollock BH, Wise BL, Zeitlinger LN, O' Donnell EF, Carr-Ascher JR, Cizik A, Ferrell B, Thorpe SW, Randall RL. Sex, racial/ethnic and socioeconomic disparities in patients with metastatic bone disease. J Surg Oncol. 2022 Mar;125(4):766-774. PubMed PMID: 34889456
• Jawad MU, Farhan S, Haffner MR, Le HV, Thorpe SW, Klineberg EO, Randall RL. Primary mobile vertebral column sarcomas: Prognostic factors vary by histologic subtypes. J Surg Oncol. 2021 Sep;124(4):635-645. PubMed PMID: 34091907
• Thai VL, Griffin KH, Thorpe SW, Randall RL, Leach JK. Tissue engineered platforms for studying primary and metastatic neoplasm behavior in bone. J Biomech. 2021 Jan 22;115:110189. PubMed PMID: 33385867
• Cruz SM, Basmaci UN, Bateni CP, Darrow MA, Judge SJ, Monjazeb AM, Thorpe SW, Humphries MD, Canter RJ. Surgical and oncologic outcomes following arterial resection and reconstruction for advanced solid tumors. J Surg Oncol. 2021 Dec;124(8):1251-1260. PubMed PMID: 34495553
• Jawad MU, Bayne CO, Farhan S, Haffner MR, Carr-Ascher J, Alvarez E, Thorpe SW, Randall RL. Prognostic factors, disparity, and equity variables impacting prognosis in bone sarcomas of the hand: SEER database review. J Surg Oncol. 2021 Dec;124(8):1515-1522. PubMed PMID: 34432316
• Jawad MU, Farhan SB, Haffner MR, Kreulen CD, Giza E, Thorpe SW, Randall RL. Malignant neoplasms originating from the bones of the foot: Predilection of hematological malignancies and sex-related and ethnic disparities in amputation. J Surg Oncol. 2021 Dec;124(8):1468-1476. PubMed PMID: 34351631
• Phan EN, Thorpe SW, Wong FS, Saiz AM, Taylor SL, Canter RJ, Lenchik L, Randall RL, Boutin RD. Opportunistic muscle measurements on staging chest CT for extremity and truncal soft tissue sarcoma are associated with survival. J Surg Oncol. 2020 Oct;122(5):869-876. PubMed PMID: 32613648
• Judge SJ, Darrow MA, Thorpe SW, Gingrich AA, O'Donnell EF, Bellini AR, Sturgill IR, Vick LV, Dunai C, Stoffel KM, Lyu Y, Chen S, Cho M, Rebhun RB, Monjazeb AM, Murphy WJ, Canter RJ. Analysis of tumor-infiltrating NK and T cells highlights IL-15 stimulation and TIGIT blockade as a combination immunotherapy strategy for soft tissue sarcomas. J Immunother Cancer. 2020 Nov;8(2). PubMed PMID: 33158916
• Gingrich AA, Marrufo AS, Liu Y, Li CS, Darrow MA, Monjazeb AM, Thorpe SW, Canter RJ. Radiotherapy is Associated With Improved Survival in Patients With Synovial Sarcoma Undergoing Surgery: A National Cancer Database Analysis. J Surg Res. 2020 Nov;255:378-387. PubMed PMID: 32599458
• Gingrich AA, Bateni SB, Monjazeb AM, Thorpe SW, Kirane AR, Bold RJ, Canter RJ. Extremity soft tissue sarcoma in the elderly: Are we overtreating or undertreating this potentially vulnerable patient population?. J Surg Oncol. 2019 Jun;119(8):1087-1098. PubMed PMID: 30977916
• Bateni SB, Gingrich AA, Jeon SY, Hoch JS, Thorpe SW, Kirane AR, Bold RJ, Canter RJ. Clinical Outcomes and Costs Following Unplanned Excisions of Soft Tissue Sarcomas in the Elderly. J Surg Res. 2019 Jul;239:125-135. PubMed PMID: 30825757
• Hinchcliff KM, Crockett J, Thorpe SW, Bayne CO. Using a kidney pump to perfuse a free filet flap for reconstruction after hemipelvectomy: A case report. Microsurgery. 2019 Feb;39(2):178-181. PubMed PMID: 29537102
• Yanagisawa M, Gingrich AA, Judge S, Li CS, Wang N, Thorpe SW, Kirane AR, Bold RJ, Monjazeb AM, Canter RJ. Serum C-reactive Protein and Neutrophil/Lymphocyte Ratio After Neoadjuvant Radiotherapy in Soft Tissue Sarcoma. Anticancer Res. 2018 Mar;38(3):1491-1497. PubMed PMID: 29491077
• Gingrich AA, Bateni SB, Monjazeb AM, Darrow MA, Thorpe SW, Kirane AR, Bold RJ, Canter RJ. Neoadjuvant Radiotherapy is Associated with R0 Resection and Improved Survival for Patients with Extremity Soft Tissue Sarcoma Undergoing Surgery: A National Cancer Database Analysis. Ann Surg Oncol. 2017 Oct;24(11):3252-3263. PubMed PMID: 28741123
• Bhale R, Ghosh P, Theriault R, Thorpe S, Loots G, Randall RL. The dynamic microenvironment associated with metastatic bone disease: Current concepts. J Surg Oncol. 2023 Sep;128(3):468-477. PubMed PMID: 37226887
• Singh A, Thorpe S, Keegan T, Maguire F, Malogolowkin M, Abrahão R, Spunt S, Carr-Asher J, Alvarez E. Localized Synovial Sarcoma: A Population-Based Analysis of Treatment Patterns and Survival. J Adolesc Young Adult Oncol. 2023 Oct;12(5):634-643. PubMed PMID: 37104039
• Zeitlinger L, Wilson M, Randall RL, Thorpe S. Surgical Duration Is Independently Associated with an Increased Risk of Surgical Site Infection and May Not Be Mitigated by Prolonged Antibiotics: A Secondary Analysis of the PARITY Trial of Infection After Lower-Extremity Endoprosthetic Reconstruction for Bone Tumors. J Bone Joint Surg Am. 2023 Jul 19;105(Suppl 1):79-86. PubMed PMID: 37466584
• Alvarez E, Spunt SL, Malogolowkin M, Li Q, Wun T, Brunson A, Thorpe S, Kreimer S, Keegan T. Treatment at Specialized Cancer Centers Is Associated with Improved Survival in Adolescent and Young Adults with Soft Tissue Sarcoma. J Adolesc Young Adult Oncol. 2022 Aug;11(4):370-378. PubMed PMID: 34910881
• Abrahão R, Keegan THM, Maguire FB, Li Q, Malogolowkin MH, Wong S, Thorpe SW, Carr-Asher JR, Midboe AM, Randall RL, Alvarez EM. Receipt of Guideline-Concordant Care Is Associated With Improved Survival in Patients With Osteosarcoma in California: A Population-Based Analysis. JCO Oncol Pract. 2024 Aug;20(8):1064-1074. PubMed PMID: 38381995
• Salerno KE, Alektiar KM, Baldini EH, Bedi M, Bishop AJ, Bradfield L, Chung P, DeLaney TF, Folpe A, Kane JM, Li XA, Petersen I, Powell J, Stolten M, Thorpe S, Trent JC, Voermans M, Guadagnolo BA. Radiation Therapy for Treatment of Soft Tissue Sarcoma in Adults: Executive Summary of an ASTRO Clinical Practice Guideline. Pract Radiat Oncol. 2021 Sep-Oct;11(5):339-351. PubMed PMID: 34326023
• Alvarez E, Malogolowkin M, Pollock BH, Li Q, Johnston E, Marina N, Wun T, Thorpe S, Keegan T. Impact of location of inpatient cancer care on patients with Ewing sarcoma and osteosarcoma-A population-based study. Pediatr Blood Cancer. 2021 Jul;68(7):e28998. PubMed PMID: 33720485
• Shah AC, Komperda KW, Mavanur AA, Thorpe SW, Weiss KR, Goodman MA. Overall survival and tumor recurrence after surgical resection for primary malignant chest wall tumors: a single-center, single-surgeon experience. J Orthop Surg (Hong Kong). 2019 May-Aug;27(2):2309499019838296. PubMed PMID: 30939982
• Thorpe SW, Tarkin IS. Deltoid compartment syndrome is a surgical emergency. J Shoulder Elbow Surg. 2010 Dec;19(8):e11-3. PubMed PMID: 20926313
• Thorpe SW, Hohl JB, Gilbert S, Tannoury CA, Lee JY. Aberrant right subclavian artery encountered during debridement of T2 osteomyelitis and associated phlegmon. Spine J. 2011 Feb;11(2):e6-10. PubMed PMID: 21296290
• Eubanks JD, Thorpe SW, Cheruvu VK, Braly BA, Kang JD. Does smoking influence fusion rates in posterior cervical arthrodesis with lateral mass instrumentation?. Clin Orthop Relat Res. 2011 Mar;469(3):696-701. PubMed PMID: 20859712
• Vlacich G, Diaz R, Thorpe SW, Murphy BA, Kirby W, Sinard RJ, Shakhtour B, Shyr Y, Murphy P, Netterville JL, Yarbrough WG, Cmelak AJ. Intensity-modulated radiation therapy with concurrent carboplatin and paclitaxel for locally advanced head and neck cancer: toxicities and efficacy. Oncologist. 2012;17(5):673-81. PubMed PMID: 22550060
• Thorpe SW, Weiss KR, Goodman MA, Heyl AE, McGough RL. Should Aggressive Surgical Local Control Be Attempted in All Patients with Metastatic or Pelvic Ewing's Sarcoma?. Sarcoma. 2012;2012:953602. PubMed PMID: 22550427
• Thorpe SW, Wukich DK. Tarsal coalitions in the adult population: does treatment differ from the adolescent?. Foot Ankle Clin. 2012 Jun;17(2):195-204. PubMed PMID: 22541520

Professional Memberships

• Connective Tissue Oncology Society, Member
• American Academy of Orthopaedic Surgeons, Fellow
• American College of Surgeons, Fellow
• Musculoskeletal Tumor Society, Member
• Society of Surgical Oncology, Fellow
• Children's Oncology Group, Member
• American Orthopedic Association, Fellow

Practice Locations

• University of Colorado Hospital
• Children's Hospital Colorado

• University of Colorado Cancer Center

Specialty Information

• Orthopedics, Board Certification (2014, 2023)

• Cancers - Sarcoma
• Cancers
• Cancers - Cancer Surgery
• Cancers - Bone Cancer
• Cancers - Pediatric Cancer