Ram Raj Prasad, PhD

Research Instructor, Medicine-Cvp-Pulmonary


FacultyPhoto
Graduate School
  • PhD, Jawaharlal Nehru University (2018)
Department
Medicine-Cvp-Pulmonary

Publications

  • Prasad RR, Kumar S, Zhang H, Li M, Hu CJ, Riddle S, McKeon BA, Frid MG, Hoetzenecker K, Crnkovic S, Kwapiszewska G, Tuder RM, Stenmark KR. An intracellular complement system drives metabolic and proinflammatory reprogramming of vascular fibroblasts in pulmonary hypertension. JCI Insight. 2025 Feb 13. [Epub ahead of print] PubMed PMID: 39946184
  • Prasad RR, Mishra N, Kant R, Fox JT, Shoemaker RH, Agarwal C, Raina K, Agarwal R. Effect of nonsteroidal anti-inflammatory drugs (aspirin and naproxen) on inflammation-associated proteomic profiles in mouse plasma and prostate during TMPRSS2-ERG (fusion)-driven prostate carcinogenesis. Mol Carcinog. 2024 Jun;63(6):1188-1204. PubMed PMID: 38506376
  • Kumar S, Mickael C, Kumar R, Prasad RR, Campbell NV, Zhang H, Li M, McKeon BA, Allen TE, Graham BB, Yu YA, Stenmark KR. Single cell transcriptomic analyses reveal diverse and dynamic changes of distinct populations of lung interstitial macrophages in hypoxia-induced pulmonary hypertension. Front Immunol. 2024;15:1372959. PubMed PMID: 38690277
  • Li M, McKeon BA, Gu S, Prasad RR, Zhang H, Kumar S, Riddle S, Irwin DC, Stenmark KR. Honokiol and Nicotinamide Adenine Dinucleotide Improve Exercise Endurance in Pulmonary Hypertensive Rats Through Increasing SIRT3 Function in Skeletal Muscle. Int J Mol Sci. 2024 Oct 29;25(21). PubMed PMID: 39519152
  • Raina K, Kandhari K, Kant R, Prasad RR, Mishra N, Maurya AK, Fox JT, Sei S, Shoemaker RH, Bosland MC, Maroni P, Agarwal C, Agarwal R. Differential Effect of Non-Steroidal Anti-Inflammatory Drugs Aspirin and Naproxen against TMPRSS2-ERG (Fusion)-Driven and Non-Fusion-Driven Prostate Cancer. Cancers (Basel). 2023 Oct 19;15(20). PubMed PMID: 37894421
  • Li M, Plecitá-Hlavatá L, Dobrinskikh E, McKeon BA, Gandjeva A, Riddle S, Laux A, Prasad RR, Kumar S, Tuder RM, Zhang H, Hu CJ, Stenmark KR. SIRT3 Is a Critical Regulator of Mitochondrial Function of Fibroblasts in Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2023 Nov;69(5):570-583. PubMed PMID: 37343939
  • Zhang H, Gerasimovskaya E, McCarthy MK, May NA, Prasad RR, Riddle S, McKeon BA, Kumar S, Li M, Hu CJ, Frid MG, Morrison TE, Stenmark KR. Local Complement Contributes to Pathogenic Activation of Lung Endothelial Cells in SARS-CoV-2 Infection. Am J Respir Cell Mol Biol. 2023 Aug;69(2):210-219. PubMed PMID: 37071849
  • Raina K, Kant R, Prasad RR, Kandhari K, Tomar M, Mishra N, Kumar R, Fox JT, Sei S, Shoemaker RH, Chen Y, Maroni P, Agarwal C, Agarwal R. Characterization of stage-specific tumor progression in TMPRSS2-ERG (fusion)-driven and non-fusion-driven prostate cancer in GEM models. Mol Carcinog. 2022 Jul;61(7):717-734. PubMed PMID: 35452553
  • Prasad RR, Raina K, Mishra N, Tomar MS, Kumar R, Palmer AE, Maroni P, Agarwal R. Stage-specific differential expression of zinc transporter SLC30A and SLC39A family proteins during prostate tumorigenesis. Mol Carcinog. 2022 May;61(5):454-471. PubMed PMID: 35049094
  • Prasad RR, Mishra DK, Kumar M, Yadava PK. Human telomerase reverse transcriptase promotes the epithelial to mesenchymal transition in lung cancer cells by enhancing c-MET upregulation. Heliyon. 2022 Jan;8(1):e08673. PubMed PMID: 35024489
  • Kumar M, Jaiswal RK, Prasad R, Yadav SS, Kumar A, Yadava PK, Singh RP. PARP-1 induces EMT in non-small cell lung carcinoma cells via modulating the transcription factors Smad4, p65 and ZEB1. Life Sci. 2021 Mar 15;269:118994. PubMed PMID: 33417952
  • Prasad RR, Paudel S, Raina K, Agarwal R. Silibinin and non-melanoma skin cancers. J Tradit Complement Med. 2020 May;10(3):236-244. PubMed PMID: 32670818
  • Mishra DK, Srivastava P, Sharma A, Prasad R, Bhuyan SK, Malage R, Kumar P, Yadava PK. Translationally controlled tumor protein (TCTP) is required for TGF-ß1 induced epithelial to mesenchymal transition and influences cytoskeletal reorganization. Biochim Biophys Acta Mol Cell Res. 2018 Jan;1865(1):67-75. PubMed PMID: 28958626
  • Kumar Bhuyan S, Bandyopadhyay P, Kumar P, Kumar Mishra D, Prasad R, Kumari A, Chandra Upadhyaya K, Varma A, Kumar Yadava P. Interaction of Piriformospora indica with Azotobacter chroococcum. Sci Rep. 2015 Sep 9;5:13911. PubMed PMID: 26350628