Jennifer Ginestra, MD

Professional Titles

• Assistant Professor, Department of Medicine
• Assistant Professor, Department of Biomedical Informatics
• Attending Physician, Division of Pulmonary Sciences & Critical Care Medicine

Research Interests

Publications

• Ginestra JC, Coz Yataco AO, Dugar SP, Dettmer MR. Hospital-Onset Sepsis Warrants Expanded Investigation and Consideration as a Unique Clinical Entity. Chest. 2024 Jun;165(6):1421-1430. PubMed PMID: 38246522
• Ginestra JC, Kohn R, Hubbard RA, Auriemma CL, Patel MS, Anesi GL, Kerlin MP, Weissman GE. Association of Time of Day with Delays in Antimicrobial Initiation among Ward Patients with Hospital-Onset Sepsis. Ann Am Thorac Soc. 2023 Sep;20(9):1299-1308. PubMed PMID: 37166187
• Mitchell OJL, Neefe S, Ginestra JC, Schweickert WD, Falk S, Weissman GE, Covin D, Shults J, Abella BS, Shashaty MGS. Association of Time to Rapid Response Team Activation With Patient Outcomes Using a Range of Physiologic Deterioration Thresholds. Crit Care Explor. 2022 Nov;4(11):e0786. PubMed PMID: 36349290
• Ginestra JC, Kohn R, Hubbard RA, Crane-Droesch A, Halpern SD, Kerlin MP, Weissman GE. Association of Unit Census with Delays in Antimicrobial Initiation among Ward Patients with Hospital-acquired Sepsis. Ann Am Thorac Soc. 2022 Sep;19(9):1525-1533. PubMed PMID: 35312462
• Mitchell OJL, Dewan M, Wolfe HA, Roberts KJ, Neefe S, Lighthall G, Sands NA, Weissman G, Ginestra J, Shashaty MGS, Schweickert WD, Abella BS. Defining Physiological Decompensation: An Expert Consensus and Retrospective Outcome Validation. Crit Care Explor. 2022 Apr;4(4):e0677. PubMed PMID: 35392439
• Ginestra JC, Mitchell OJL, Anesi GL, Christie JD. COVID-19 Critical Illness: A Data-Driven Review. Annu Rev Med. 2022 Jan 27;73:95-111. PubMed PMID: 34520220
• Mitchell OJL, Neefe S, Ginestra JC, Baston CM, Frazer MJ, Gudowski S, Min J, Ahmed NH, Pascual JL, Schweickert WD, Anderson BJ, Anesi GL, Falk SA, Shashaty MGS. Impact of COVID-19 on inpatient clinical emergencies: A single-center experience. Resusc Plus. 2021 Jun;6:100135. PubMed PMID: 33969324
• Shah PK, Ginestra JC, Ungar LH, Junker P, Rohrbach JI, Fishman NO, Weissman GE. A Simulated Prospective Evaluation of a Deep Learning Model for Real-Time Prediction of Clinical Deterioration Among Ward Patients. Crit Care Med. 2021 Aug 1;49(8):1312-1321. PubMed PMID: 33711001
• Ginestra JC, Giannini HM, Schweickert WD, Meadows L, Lynch MJ, Pavan K, Chivers CJ, Draugelis M, Donnelly PJ, Fuchs BD, Umscheid CA. Clinician Perception of a Machine Learning-Based Early Warning System Designed to Predict Severe Sepsis and Septic Shock. Crit Care Med. 2019 Nov;47(11):1477-1484. PubMed PMID: 31135500
• Giannini HM, Ginestra JC, Chivers C, Draugelis M, Hanish A, Schweickert WD, Fuchs BD, Meadows L, Lynch M, Donnelly PJ, Pavan K, Fishman NO, Hanson CW 3rd, Umscheid CA. A Machine Learning Algorithm to Predict Severe Sepsis and Septic Shock: Development, Implementation, and Impact on Clinical Practice. Crit Care Med. 2019 Nov;47(11):1485-1492. PubMed PMID: 31389839
• *Schneider ALC, *Ginestra JC, Kerlin MP, et al. The Complete Inpatient Record Using Comprehensive Electronic Data (CIRCE) project: A team-based approach to clinically validated, research-ready electronic health record data. Learn Health Sys. 2024;e10439. doi:10.1002/lrh2.10439 *co-first authors
• Ginestra JC, Atkins J, Mikkelsen M, Mitchell OJL, Gutsche J, Jablonski J, Panchanadam V, Junker P, Schweickert W, Anesi G, Anderson B, Pierce M, Fuchs BD, Wani AA. The I-READI Quality and Safety Framework: A Health System’s Response to Airway Complications in Mechanically Ventilated Patients with Covid-19. NEJM Catal Innov Care Deliv. 2020 Dec 16;2(1):10.1056/CAT.20.0305. doi: 10.1056/CAT.20.0305. PMCID: PMC7743892.

Professional Memberships

• American Thoracic Society, Member

Practice Locations

• University of Colorado Hospital

Specialty Information

• Critical Care Medicine, Board Certification (2022)
• Pulmonary Disease, Board Certification (2021)
• Internal Medicine, Board Certification (2018)
• Healthcare Improvement and Patient Safety, Certificate (2020)

• Critical Care
• Infections
• Lungs and Breathing