Lynn Hassman, MD, PhD
Assistant Professor, Ophthalmology

Professional Titles

• Assistant Professor

Research Interests

Publications

• Paley MA, Baker BJ, Dunham SR, Linskey N, Cantoni C, Lee K, Hassman LM, Laurent J, Roberson EDO, Clifford DB, Yokoyama WM. The CSF in neurosarcoidosis contains consistent clonal expansion of CD8 T cells, but not CD4 T cells. J Neuroimmunol. 2022 Jun 15;367:577860. PubMed PMID: 35405431
• Yang X, Garner LI, Zvyagin IV, Paley MA, Komech EA, Jude KM, Zhao X, Fernandes RA, Hassman LM, Paley GL, Savvides CS, Brackenridge S, Quastel MN, Chudakov DM, Bowness P, Yokoyama WM, McMichael AJ, Gillespie GM, Garcia KC. Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature. 2022 Dec;612(7941):771-777. PubMed PMID: 36477533
• Hassman LM, Paley MA, Esaulova E, Paley GL, Ruzycki PA, Linskey N, Laurent J, Feigl-Lenzen L, Springer L, Montana CL, Hong K, Enright J, James H, Artyomov MN, Yokoyama WM. Clinicomolecular Identification of Conserved and Individualized Features of Granulomatous Uveitis. Ophthalmol Sci. 2021 Mar;1(1). PubMed PMID: 35937550
• Rosenbaum JT, Harrington CA, Searles RP, Fei SS, Zaki A, Arepalli S, Paley MA, Hassman LM, Vitale AT, Conrady CD, Keath P, Mitchell C, Watson L, Planck SR, Martin TM, Choi D. Identifying RNA Biomarkers and Molecular Pathways Involved in Multiple Subtypes of Uveitis. Am J Ophthalmol. 2021 Jun;226:226-234. PubMed PMID: 33503442
• Rosenbaum JT, Harrington CA, Searles RP, Fei SS, Zaki A, Arepalli S, Paley MA, Hassman LM, Vitale AT, Conrady CD, Keath P, Mitchell C, Watson L, Planck SR, Martin TM, Choi D. Revising the Diagnosis of Idiopathic Uveitis by Peripheral Blood Transcriptomics. Am J Ophthalmol. 2021 Feb;222:15-23. PubMed PMID: 32941857
• Hassman LM, Chung MM, Gonzalez M, Bessette AP. Herpetic Panophthalmitis: A Diagnostic Dilemma. Ocul Immunol Inflamm. 2020;28(1):116-118. PubMed PMID: 30444434
• Borah S, Nichols LA, Hassman LM, Kedes DH, Steitz JA. Tracking expression and subcellular localization of RNA and protein species using high-throughput single cell imaging flow cytometry. RNA. 2012 Aug;18(8):1573-9. PubMed PMID: 22745225
• Hassman LM, Ellison TJ, Kedes DH. KSHV infects a subset of human tonsillar B cells, driving proliferation and plasmablast differentiation. J Clin Invest. 2011 Feb;121(2):752-68. PubMed PMID: 21245574
• Fulkerson PC, Fischetti CA, Hassman LM, Nikolaidis NM, Rothenberg ME. Persistent effects induced by IL-13 in the lung. Am J Respir Cell Mol Biol. 2006 Sep;35(3):337-46. PubMed PMID: 16645178
• Fulkerson PC, Fischetti CA, McBride ML, Hassman LM, Hogan SP, Rothenberg ME. A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16418-23. PubMed PMID: 17060636
• Fulkerson PC, Zimmermann N, Hassman LM, Finkelman FD, Rothenberg ME. Pulmonary chemokine expression is coordinately regulated by STAT1, STAT6, and IFN-gamma. J Immunol. 2004 Dec 15;173(12):7565-74. PubMed PMID: 15585884
• • Sabapathypillai A, Miller TJ, Shakoor A, Palestine AG, Thorne JE, Goldstein DA, Gaudio PA, Goldberg N, Vitale A, Schlaen A, Thomas A, Merrill PT, Rajii V, Lin P, Oliver A, Moorthy RS, Chandra G, Carreno E, Smith WM, Van Stavern G, Hassman LM. Optic disc edema is an under-recognized feature of birdshot chorioretinitis. Journal of Neuro-ophthalmology
• Lin JB, Pepple, KL, Concepcion C, Korsunova Y, Paley MA, Paley GL, Laurent J, Apte AS, Hassman LM. Aqueous macrophages contribute to conserved CCL2 and CXCL10 gradients in uveitis. Ophthalmology science, in press
• Guess R, Harocopos G, Bednarski JJ, Hassman LM, Bigley TM. Pediatric Necrobiotic Xanthogranuloma as a Novel Phenotype of IKAROS Gain of Function. Journal of Clinical Immunology

Professional Memberships

• Association of Eye and Vision Research, Planning Committee Member
• American Uveitis Society, member, liason for FOCIS
• Federation of Clinical Immunuology Societies, member, liason for the American Uveitis Society
• American Academy of Ophthalmology, member