Jose Miranda, PhD, MS, BS

Professional Titles

• Research Instructor

Publications

• St Clair JR, Westacott MJ, Miranda J, Farnsworth NL, Kravets V, Schleicher WE, Dwulet JM, Levitt CH, Heintz A, Ludin NWF, Benninger RKP. Restoring connexin-36 function in diabetogenic environments precludes mouse and human islet dysfunction. J Physiol. 2023 Sep;601(18):4053-4072. PubMed PMID: 37578890
• Miranda JG, Schleicher WE, Wells KL, Ramirez DG, Landgrave SP, Benninger RKP. Dynamic changes in ß-cell [Ca(2+)] regulate NFAT activation, gene transcription, and islet gap junction communication. Mol Metab. 2022 Mar;57:101430. PubMed PMID: 34979329
• Kim YK, Walters JA, Moss ND, Wells KL, Sheridan R, Miranda JG, Benninger RKP, Pyle LL, O'Brien RM, Sussel L, Davidson HW. Zinc transporter 8 haploinsufficiency protects against beta cell dysfunction in type 1 diabetes by increasing mitochondrial respiration. Mol Metab. 2022 Dec;66:101632. PubMed PMID: 36347424
• Farnsworth NL, Piscopio RA, Schleicher WE, Ramirez DG, Miranda JG, Benninger RKP. Modulation of Gap Junction Coupling Within the Islet of Langerhans During the Development of Type 1 Diabetes. Front Physiol. 2022;13:913611. PubMed PMID: 35837011
• Corezola do Amaral ME, Kravets V, Dwulet JM, Farnsworth NL, Piscopio R, Schleicher WE, Miranda JG, Benninger RKP. Caloric restriction recovers impaired ß-cell-ß-cell gap junction coupling, calcium oscillation coordination, and insulin secretion in prediabetic mice. Am J Physiol Endocrinol Metab. 2020 Oct 1;319(4):E709-E720. PubMed PMID: 32830549
• Qin Y, Miranda JG, Stoddard CI, Dean KM, Galati DF, Palmer AE. Direct comparison of a genetically encoded sensor and small molecule indicator: implications for quantification of cytosolic Zn(2+). ACS Chem Biol. 2013 Nov 15;8(11):2366-71. PubMed PMID: 23992616
• Miranda JG, Weaver AL, Qin Y, Park JG, Stoddard CI, Lin MZ, Palmer AE. New alternately colored FRET sensors for simultaneous monitoring of Zn²? in multiple cellular locations. PLoS One. 2012;7(11):e49371. PubMed PMID: 23173058
• Dittmer PJ, Miranda JG, Gorski JA, Palmer AE. Genetically encoded sensors to elucidate spatial distribution of cellular zinc. J Biol Chem. 2009 Jun 12;284(24):16289-16297. PubMed PMID: 19363034
• Old WM, Shabb JB, Houel S, Wang H, Couts KL, Yen CY, Litman ES, Croy CH, Meyer-Arendt K, Miranda JG, Brown RA, Witze ES, Schweppe RE, Resing KA, Ahn NG. Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma. Mol Cell. 2009 Apr 10;34(1):115-31. PubMed PMID: 19362540

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