Kibrom Alula, PhD

Publications

• Alula KM, Delgado-Deida Y, Callahan R, Till A, Underwood L, Thompson WE, Souza RF, Dassopoulos T, Onyiah J, Venuprasad K, Theiss AL. Inner mitochondrial membrane protein Prohibitin 1 mediates Nix-induced, Parkin-independent mitophagy. Sci Rep. 2023 Jan 2;13(1):18. doi: 10.1038/s41598-022-26775-x. PMID: 36593241; PMCID: PMC9807637.
• Kibrom Alula Alexander Dowdell Joseph Lee Sean Colgan Arianne Theiss DOI:https://doi.org/10.1053/j.gastro.2023.03.120
• Alula KM, Theiss AL. Autophagy in Crohn's Disease: Converging on Dysfunctional Innate Immunity. Cells. 2023 Jul 4;12(13):1779. doi: 10.3390/cells12131779. PMID: 37443813; PMCID: PMC10341259.
• Amo-Aparicio J, Dominguez A, Atif SM, Dinarello A, Azam T, Alula KM, Piper M, Lieu CH, Lentz RW, Leal AD, Bagby SM, Messersmith WA, Karam SD, Dinarello CA, Pitts TM, Marchetti C. Pancreatic Ductal Adenocarcinoma Cells Regulate NLRP3 Activation to Generate a Tolerogenic Microenvironment. Cancer Res Commun. 2023 Sep 20;3(9):1899-1911. doi: 10.1158/2767-9764.CRC-23-0065. PMID: 37772994; PMCID: PMC10510589.
• Title: Regulation of Intestinal Regulatory T Cells via Stress Response Pathways Submitted to the "International Reviews of Immunology" journal.
• Presented in the "CCTSI Pediatric Research Poster Session" held on June 21, 2024 from 12-2pm at the Princeton/Yale Conference room.
• Collins CB, Nguyen TT, Leddy RS, Alula KM, Yeckes AR, Strassheim D, Aherne CM, Luck ME, Karoor V, Jedlicka P, Pierce A, de Zoeten EF. Heat shock factor 1 drives regulatory T cell induction to limit murine intestinal inflammation. Mucosal Immunol. 2023 Nov 7:S1933-0219(23)00086-7. doi: 10.1016/j.mucimm.2023.11.003. Epub ahead of print. PMID: 37944754.
• Alula, K.M., Dowdell, A.S., LeBere, B. et al. Interplay of gut microbiota and host epithelial mitochondrial dysfunction is necessary for the development of spontaneous intestinal inflammation in mice. Microbiome 11, 256 (2023). https://doi.org/10.1186/s40168-023-01686-9