Felix Poppelaars, MD, PhD

Publications

• Poppelaars F, Daha MR. Granzyme K sets complement in motion. Kidney Int. 2026 Mar;109(3):423-426. PubMed PMID: 41101357
• Renner B, Laskowski J, Poppelaars F, Whelan R, Milliron K, Petr V, Blaine J, Ozekin Y, Ferreira VP, Pickering MC, Schmidt CQ, Hajjar K, Davidson A, Thurman JM. Annexin A2 interferes with complement regulation within the glomerulus. J Biol Chem. 2025 Oct;301(10):110657. PubMed PMID: 40889685
• Poppelaars F, Holers VM, Thurman JM. Friend or foe: assessing the value of animal models for facilitating clinical breakthroughs in complement research. J Clin Invest. 2025 Jun 16;135(12). PubMed PMID: 40519165
• Petr V, Tichanek F, Liu SL, Poppelaars F, Renner B, Laskowski J, Purohit S, Zhao M, Jalal D, Heeger PS, Thurman JM. Pretransplant natural antibody levels identify a subset of deceased donor kidney transplant recipients that benefit from infliximab induction. Am J Transplant. 2025 Oct;25(10):2173-2181. PubMed PMID: 40484132
• Poppelaars F, Faria B, Thurman JM. Alternative Complement Pathway, Iptacopan, and IgA Nephropathy. N Engl J Med. 2025 May 15;392(19):1975. PubMed PMID: 40367385
• van Rossum M, Veuskens BRJ, Brouwer MC, van Mierlo G, Lucientes-Continente L, Goicoechea de Jorge E, Uzonyi B, Matola AT, Józsi M, Müller G, Meter-Arkema AM, Poppelaars F, Pauly D, Pouw RB, Toonen EJM. Development and Characterization of Novel ELISAs for the Specific Quantification of the Factor H-Related Proteins 2, 3, 4, and 5. J Innate Immun. 2025;17(1):226-243. PubMed PMID: 40139166
• E de Carlo Forest T, Marin AI, Gill Z, Gnanaraj R, Patnaik JL, Poppelaars F, Lynch AM, Palestine AG, Mathias MT, Manoharan N, Frazer-Abel AA, Holers VM, Mandava N. Association between systemic complement levels and choroidal thickness in advanced non-neovascular age-related macular degeneration. Sci Rep. 2025 Dec 6;16(1):1442. PubMed PMID: 41353467
• Faria B, Gaya da Costa M, Meter-Arkema AH, Berger SP, Lima C, Pêgo C, van den Born J, Franssen CF, Daha MR, Pestana M, Seelen MA, Poppelaars F. Systemic and local complement activation in peritoneal dialysis patients via conceivably distinct pathways. Perit Dial Int. 2024 Jan;44(1):37-47. PubMed PMID: 37794761
• Faria B, Gaya da Costa M, Meter-Arkema AH, Berger SP, Lima C, Pêgo C, van den Born J, Franssen CF, Daha MR, Pestana M, Seelen MA, Poppelaars F. Systemic and local complement activation in peritoneal dialysis patients via conceivably distinct pathways. Perit Dial Int. 2024 Jan;44(1):37-47. PubMed PMID: 37794761
• Whelan R, Feemster A, Laskowski J, Renner B, Kulik L, Poppelaars F, Lee C, Holers VM, Thurman JM. Female but Not Male Mice Deficient in Soluble IgM Are Susceptible to Chemically Induced Glomerular Injury. J Immunol. 2023 Oct 15;211(8):1240-1248. PubMed PMID: 37682538
• Poppelaars F, Eskandari SK, Damman J, Seelen MA, Faria B, Gaya da Costa M. A non-muscle myosin heavy chain 9 genetic variant is associated with graft failure following kidney transplantation. Kidney Res Clin Pract. 2023 May;42(3):389-402. PubMed PMID: 37313613
• Renner B, Poppelaars F, Laskowski J, Serkova NJ, Kulik L, Holers VM, Thurman JM. Noninvasive Detection of iC3b/C3d Deposits in the Kidney Using a Novel Bioluminescent Imaging Probe. J Am Soc Nephrol. 2023 Jul 1;34(7):1151-1154. PubMed PMID: 36995143
• Giang J, van Doorn MBA, Diercks GFH, de Cordoba SR, van den Bosch TPP, Schreurs MWJ, Poppelaars F, Damman J. Successful pharmacological intervention at different levels of the complement system in an in vitro complement fixation model for bullous pemphigoid. Exp Dermatol. 2023 May;32(5):632-640. PubMed PMID: 36704908

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Specialty Information

Specialties

• Psychology