Michael Rudy, PhD
Assistant Research Professor, Neurology
Graduate Schools
- MS, University of Rochester (2013)
- PhD, University of Rochester (2017)
Department
NeurologyPublications
- Leser JS, Frost JL, Wilson CJ, Rudy MJ, Clarke P, Tyler KL. VP1 is the primary determinant of neuropathogenesis in a mouse model of enterovirus D68 acute flaccid myelitis. J Virol. 2024 Jul 23;98(7):e0039724. PubMed PMID: 38869283
- Frost J, Rudy MJ, Leser JS, Tan H, Hu Y, Wang J, Clarke P, Tyler KL. Telaprevir Treatment Reduces Paralysis in a Mouse Model of Enterovirus D68 Acute Flaccid Myelitis. J Virol. 2023 May 31;97(5):e0015623. doi: 10.1128/jvi.00156-23. Epub 2023 May 8. PMID: 37154751; PMCID: PMC10231134.
- Rudy MJ, Salois G, Cubello J, Newell R, Mayer-Proschel M. Gestational iron deficiency affects the ratio between interneuron subtypes in the postnatal cerebral cortex in mice. Development. 2023 Oct 15;150(20). PubMed PMID: 36805633
- Lane TR, Fu J, Sherry B, Tarbet B, Hurst BL, Riabova O, Kazakova E, Egorova A, Clarke P, Leser JS, Frost J, Rudy M, Tyler KL, Klose T, Volobueva AS, Belyaevskaya SV, Zarubaev VV, Kuhn RJ, Makarov V, Ekins S. Efficacy of an isoxazole-3-carboxamide analog of pleconaril in mouse models of Enterovirus-D68 and Coxsackie B5. Antiviral Res. 2023 Aug;216:105654. PubMed PMID: 37327878
- Rudy MJ, Coughlan C, Hixon AM, Clarke P, Tyler KL. Density Analysis of Enterovirus D68 Shows Viral Particles Can Associate with Exosomes. Microbiol Spectr. 2022 Feb 23;10(1):e0245221. PubMed PMID: 35170992
- Rudy MJ, Frost J, Clarke P, Tyler KL. Neutralizing Antibody Given after Paralysis Onset Reduces the Severity of Paralysis Compared to Nonspecific Antibody-Treated Controls in a Mouse Model of EV-D68-Associated Acute Flaccid Myelitis. Antimicrob Agents Chemother. 2022 Aug 16;66(8):e0022722. PubMed PMID: 35894595
- Rudy MJ, Frost J, Clarke P, Tyler KL. Neutralizing Antibody Given after Paralysis Onset Reduces the Severity of Paralysis Compared to Nonspecific Antibody-Treated Controls in a Mouse Model of EV-D68-Associated Acute Flaccid Myelitis. Antimicrob Agents Chemother. 2022 Aug 16;66(8):e0022722. PubMed PMID: 35894595
- Rudy MJ, Coughlan C, Hixon AM, Clarke P, Tyler KL. Density Analysis of Enterovirus D68 Shows Viral Particles Can Associate with Exosomes. Microbiol Spectr. 2022 Feb 23;10(1):e0245221. PubMed PMID: 35170992
- Flores-Bellver M, Mighty J, Aparicio-Domingo S, Li KV, Shi C, Zhou J, Cobb H, McGrath P, Michelis G, Lenhart P, Bilousova G, Heissel S, Rudy MJ, Coughlan C, Goodspeed AE, Becerra SP, Redenti S, Canto-Soler MV. Extracellular vesicles released by human retinal pigment epithelium mediate increased polarised secretion of drusen proteins in response to AMD stressors. J Extracell Vesicles. 2021 Nov;10(13):e12165. PubMed PMID: 34750957
- Flores-Bellver M, Mighty J, Aparicio-Domingo S, Li KV, Shi C, Zhou J, Cobb H, McGrath P, Michelis G, Lenhart P, Bilousova G, Heissel S, Rudy MJ, Coughlan C, Goodspeed AE, Becerra SP, Redenti S, Canto-Soler MV. Extracellular vesicles released by human retinal pigment epithelium mediate increased polarised secretion of drusen proteins in response to AMD stressors. J Extracell Vesicles. 2021 Nov;10(13):e12165. PubMed PMID: 34750957
- Hixon AM, Frost J, Rudy MJ, Messacar K, Clarke P, Tyler KL. Understanding Enterovirus D68-Induced Neurologic Disease: A Basic Science Review. Viruses. 2019 Sep 4;11(9). PubMed PMID: 31487952
- Rudy M, Mayer-Proschel M. Iron Deficiency Affects Seizure Susceptibility in a Time- and Sex-Specific Manner. ASN Neuro. 2017 Nov-Dec;9(6):1759091417746521. PubMed PMID: 29243938
Public Speaking
Yes
I have spoken on a diverse array of scientific topics including 1) edible, medicinal, and poisonous plants; 2) viral, mycotic, and bacterial pathogens; 3) neurodevelopment and transcription factor modulators; 4) human anatomy and physiology; and 5) the skull morphology of snakes, lizards, birds, crocodilians, and theropod dinosaurs.
Yes
I have spoken on a diverse array of scientific topics including 1) edible, medicinal, and poisonous plants; 2) viral, mycotic, and bacterial pathogens; 3) neurodevelopment and transcription factor modulators; 4) human anatomy and physiology; and 5) the skull morphology of snakes, lizards, birds, crocodilians, and theropod dinosaurs.