Iain Konigsberg, PhD
Research Instructor, Biomedical Informatics
Graduate School
- PhD, University of Colorado Health Sciences Center (2021)
Undergraduate School
- BS, Indiana University–Bloomington (IN) (2016)
Languages
EnglishDepartment
Biomedical InformaticsPublications
- Konigsberg IR, Yang IV. Differential Methylation of Chronic Obstructive Pulmonary Disease Lung Macrophage Genes Sheds Light on Disease Pathogenesis. Am J Respir Cell Mol Biol. 2022 Jun;66(6):589-590. PubMed PMID: 35377834
- Pan J, Li W, Ni J, Wu K, Konigsberg I, Rivera CE, Tincher C, Gregory C, Zhou X, Doak TG, Lee H, Wang Y, Gao X, Lynch M, Long H. Rates of Mutations and Transcript Errors in the Foodborne Pathogen Salmonella enterica subsp. enterica. Mol Biol Evol. 2022 Apr 10;39(4). PubMed PMID: 35446958
- Borie R, Cardwell J, Konigsberg IR, Moore CM, Zhang W, Sasse SK, Gally F, Dobrinskikh E, Walts A, Powers J, Brancato J, Rojas M, Wolters PJ, Brown KK, Blackwell TS, Nakanishi T, Richards JB, Gerber AN, Fingerlin TE, Sachs N, Pulit SL, Zappala Z, Schwartz DA, Yang IV. Colocalization of Gene Expression and DNA Methylation with Genetic Risk Variants Supports Functional Roles of MUC5B and DSP in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2022 Nov 15;206(10):1259-1270. PubMed PMID: 35816432
- Arnold CG, Konigsberg I, Adams JY, Sharma S, Aggarwal N, Hopkinson A, Vest A, Campbell M, Boorgula M, Yang I, Gignoux C, Barnes KC, Monte AA. Epigenetics may characterize asymptomatic COVID-19 infection. Hum Genomics. 2022 Jul 27;16(1):27. PubMed PMID: 35897116
- Konigsberg IR, Borie R, Walts AD, Cardwell J, Rojas M, Metzger F, Hauck SM, Fingerlin TE, Yang IV, Schwartz DA. Molecular Signatures of Idiopathic Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2021 Oct;65(4):430-441. PubMed PMID: 34038697
- Siebert JC, Stanislawski MA, Zaman A, Ostendorf DM, Konigsberg IR, Jambal P, Ir D, Bing K, Wayland L, Scorsone JJ, Lozupone CA, Görg C, Frank DN, Bessesen D, MacLean PS, Melanson EL, Catenacci VA, Borengasser SJ. Multiomic Predictors of Short-Term Weight Loss and Clinical Outcomes During a Behavioral-Based Weight Loss Intervention. Obesity (Silver Spring). 2021 May;29(5):859-869. PubMed PMID: 33811477
- Konigsberg IR, Maier LA, Yang IV. Epigenetics and sarcoidosis. Eur Respir Rev. 2021 Jun 30;30(160). PubMed PMID: 34168064
- Li L, Konigsberg IR, Bhargava M, Liu S, MacPhail K, Mayer A, Davidson EJ, Liao SY, Lei Z, Mroz PM, Fingerlin TE, Yang IV, Maier LA. Multiomic Signatures of Chronic Beryllium Disease Bronchoalveolar Lavage Cells Relate to T-Cell Function and Innate Immunity. Am J Respir Cell Mol Biol. 2022 Dec;67(6):632-640. PubMed PMID: 35972918
- Liao SY, Atif SM, Mould K, Konigsberg IR, Fu R, Davidson E, Li L, Fontenot AP, Maier LA, Yang IV. Single-cell RNA sequencing identifies macrophage transcriptional heterogeneities in granulomatous diseases. Eur Respir J. 2021 Jun;57(6). PubMed PMID: 33602861
- Vargas LB, Lange LA, Ferrier K, Aguet F, Ardlie K, Gabriel S, Gupta N, Smith JD, Blackwell TW, Ding J, Durda P, Tracy RP, Liu Y, Taylor KD, Craig Johnson W, Rich SS, Rotter JI, Lange EM, Konigsberg IR. Gene expression associations with body mass index in the Multi-Ethnic Study of Atherosclerosis. Int J Obes (Lond). 2022 Dec 3. [Epub ahead of print] PubMed PMID: 36463326
- Konigsberg IR, Barnes B, Campbell M, Davidson E, Zhen Y, Pallisard O, Boorgula MP, Cox C, Nandy D, Seal S, Crooks K, Sticca E, Harrison GF, Hopkinson A, Vest A, Arnold CG, Kahn MG, Kao DP, Peterson BR, Wicks SJ, Ghosh D, Horvath S, Zhou W, Mathias RA, Norman PJ, Porecha R, Yang IV, Gignoux CR, Monte AA, Taye A, Barnes KC. Host methylation predicts SARS-CoV-2 infection and clinical outcome. Commun Med (Lond). 2021;1(1):42. PubMed PMID: 35072167
- Furusawa H, Cardwell JH, Okamoto T, Walts AD, Konigsberg IR, Kurche JS, Bang TJ, Schwarz MI, Brown KK, Kropski JA, Rojas M, Cool CD, Lee JS, Wolters PJ, Yang IV, Schwartz DA. Chronic Hypersensitivity Pneumonitis, an Interstitial Lung Disease with Distinct Molecular Signatures. Am J Respir Crit Care Med. 2020 Nov 15;202(10):1430-1444. PubMed PMID: 32602730
- Konigsberg IR, Yang IV. It's in the (Epi)genetics: Effects of DNA Methylation on Gene Expression in Atopic Asthma?. Chest. 2020 Nov;158(5):1799-1801. PubMed PMID: 33160517
- Yang IV, Konigsberg I, MacPhail K, Li L, Davidson EJ, Mroz PM, Hamzeh N, Gillespie M, Silveira LJ, Fingerlin TE, Maier LA. DNA Methylation Changes in Lung Immune Cells Are Associated with Granulomatous Lung Disease. Am J Respir Cell Mol Biol. 2019 Jan;60(1):96-105. PubMed PMID: 30141971
- Vargas LB, Lange LA, Ferrier K, Aguet F, Ardlie K, Gabriel S, Gupta N, Smith JD, Blackwell TW, Ding J, Durda P, Tracy RP, Liu Y, Taylor KD, Craig Johnson W, Rich SS, Rotter JI, Lange EM, Konigsberg IR. Gene expression associations with body mass index in the Multi-Ethnic Study of Atherosclerosis. Int J Obes (Lond). 2023 Feb;47(2):109-116. PubMed PMID: 36463326
- Konigsberg IR, Lin NW, Liao SY, Liu C, MacPhail K, Mroz MM, Davidson E, Restrepo CI, Sharma S, Li L, Maier LA, Yang IV. Multi-Omic Signatures of Sarcoidosis and Progression in Bronchoalveolar Lavage Cells. bioRxiv. 2023 Jan 27. PubMed PMID: 36747844
- Hill AC, Guo C, Litkowski EM, Manichaikul AW, Yu B, Konigsberg IR, Gorbet BA, Lange LA, Pratte KA, Kechris KJ, DeCamp M, Coors M, Ortega VE, Rich SS, Rotter JI, Gerzsten RE, Clish CB, Curtis JL, Hu X, Obeidat ME, Morris M, Loureiro J, Ngo D, O'Neal WK, Meyers DA, Bleecker ER, Hobbs BD, Cho MH, Banaei-Kashani F, Bowler RP. Large scale proteomic studies create novel privacy considerations. Sci Rep. 2023 Jun 7;13(1):9254. PubMed PMID: 37286633
- Hill EB, Konigsberg IR, Ir D, Frank DN, Jambal P, Litkowski EM, Lange EM, Lange LA, Ostendorf DM, Scorsone JJ, Wayland L, Bing K, MacLean PS, Melanson EL, Bessesen DH, Catenacci VA, Stanislawski MA, Borengasser SJ. The Microbiome, Epigenome, and Diet in Adults with Obesity during Behavioral Weight Loss. Nutrients. 2023 Aug 16;15(16). PubMed PMID: 37630778
- Abulnoor BA, Attia MH, Konigsberg IR, Konigsberg LW. TestDimorph: An R package for analysis of interpopulation sexual dimorphism differences using summary statistics. Am J Biol Anthropol. 2023 Nov;182(3):487-498. PubMed PMID: 37694912
- Li X, Chen H, Selvaraj MS, Van Buren E, Zhou H, Wang Y, Sun R, McCaw ZR, Yu Z, Arnett DK, Bis JC, Blangero J, Boerwinkle E, Bowden DW, Brody JA, Cade BE, Carson AP, Carlson JC, Chami N, Chen YI, Curran JE, de Vries PS, Fornage M, Franceschini N, Freedman BI, Gu C, Heard-Costa NL, He J, Hou L, Hung YJ, Irvin MR, Kaplan RC, Kardia SLR, Kelly T, Konigsberg I, Kooperberg C, Kral BG, Li C, Loos RJF, Mahaney MC, Martin LW, Mathias RA, Minster RL, Mitchell BD, Montasser ME, Morrison AC, Palmer ND, Peyser PA, Psaty BM, Raffield LM, Redline S, Reiner AP, Rich SS, Sitlani CM, Smith JA, Taylor KD, Tiwari H, Vasan RS, Wang Z, Yanek LR, Yu B, Rice KM, Rotter JI, Peloso GM, Natarajan P, Li Z, Liu Z, Lin X. A statistical framework for powerful multi-trait rare variant analysis in large-scale whole-genome sequencing studies. bioRxiv. 2023 Nov 2. PubMed PMID: 37961350
- Liu W, Vu T, Konigsberg IR, Pratte KA, Zhuang Y, Kechris KJ. SmCCNet 2.0: an Upgraded R package for Multi-omics Network Inference. bioRxiv. 2023 Nov 21. PubMed PMID: 38045372
Professional Memberships
- American Society of Human Genetics, Member
- American Thoracic Society, Member
Public Speaking
Yes
I am comfortable and experienced speaking on topics related to: genetics & genetic disease, omics and multi-omic integration, genetics and omics of lung disease, considerations of use of population descriptors in genetic studies.
Yes
I am comfortable and experienced speaking on topics related to: genetics & genetic disease, omics and multi-omic integration, genetics and omics of lung disease, considerations of use of population descriptors in genetic studies.