Jill Chang, MD

Professional Titles

• Assistant Professor

Recognitions

• Pediatric Physician Scientist Research Award (PPSRA) Program, Ann & Robert H. Lurie Children's Hospital of Chicago (2018)
• Neonatology Young Research Scholar, Founders' Board of Ann & Robert H. Lurie Children's Hospital of Chicago (2021)
• Young Investigator Coaching Program Recipient, Society of Pediatric Research (2018)

Research Interests

My research focuses on understanding and preventing neonatal brain injury that leads to movement disorders including cerebral palsy. To do this, my laboratory looks at changes that occur at the cellular level to find ways to rescue and promote healing of the brain. My research currently focuses on two common disorders seen in the NICU that put infants at risk for cerebral palsy: maternal pre-eclampsia resulting in infant intrauterine growth restriction and bronchopulmonary dysplasia. The ultimate goal of my work is the early detection and treatment of babies with brain injury to ensure the best neurodevelopmental outcomes.

Publications

• Brown AS, Wieben M, Murdock S, Chang J, Dizon MLV, St Pierre M, Chavez-Valdez R, Dorsky RI, Fung CM. Intrauterine Growth Restriction Causes Abnormal Embryonic Dentate Gyrus Neurogenesis in Mouse Offspring That Leads to Adult Learning and Memory Deficits. eNeuro. 2021 Sep-Oct;8(5). PubMed PMID: 34544755
• Chang J. 50 Years Ago in The Journal of Pediatrics: Central Nervous System Damage and Hypoglycemia. J Pediatr. 2018 Jun;197:220. PubMed PMID: 29801540
• Chang J, Dettman RW, Dizon MLV. Bone morphogenetic protein signaling: a promising target for white matter protection in perinatal brain injury. Neural Regen Res. 2018 Jul;13(7):1183-1184. PubMed PMID: 30028321
• Chang JL, Bashir M, Santiago C, Farrow K, Fung C, Brown AS, Dettman RW, Dizon MLV. Intrauterine Growth Restriction and Hyperoxia as a Cause of White Matter Injury. Dev Neurosci. 2018;40(4):344-357. PubMed PMID: 30428455
• Berken JA, Chang J. Neurologic consequences of neonatal necrotizing enterocolitis. Dev Neurosci. 2022 Jun 13. [Epub ahead of print] PubMed PMID: 35697005
• Mathias M, Chang J, Perez M, Saugstad O. Supplemental Oxygen in the Newborn: Historical Perspective and Current Trends. Antioxidants (Basel). 2021 Nov 25;10(12). PubMed PMID: 34942982
• Chang J, Mestan K. Placental Function in Intrauterine Growth Restriction. In R. Polin, S. Abman, D. Rowitch, W. Benitz (Eds.), Fetal and Neonatal Physiology (6th ed., pp 137-149). Elsevier
• Chang J, Lurie RH, Sharma A, Bashir M, Fung CM, Dettman RW, Dizon MLV. Intrauterine growth restriction followed by oxygen support uniquely interferes with genetic regulators of myelination. eNeuro. 2021 Jun 7. [Epub ahead of print] PubMed PMID: 34099489
• Berken JA, Chang J. Neurologic Consequences of Neonatal Necrotizing Enterocolitis. Dev Neurosci. 2022;44(4-5):295-308. PubMed PMID: 35697005

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation

• University of Colorado Hospital
• Children's Hospital Colorado

Center Affiliations

• Perinatal Research Center

Specialty Information

Specialties

• Neonatal-Perinatal Medicine, Board Certification
• Pediatrics, Board Certification