Samuel Guzman, MD

Publications

• Characterization of Spastic Paraplegia in a Family with a Novel PSEN1 Mutation
• L Alksman, S Guzman, J Ringman. Data-driven comparison of neurodegeneration patterns between autosomal dominant and sporadic late-onset Alzheimer’s disease. Alzheimer’s Association International Conference. 2023.
• Samuel Guzman, John Ringman. In-vivo and post-mortem retinal and brain pathological findings in a homozygote for the A431E PSEN1 mutation. Alzheimer’s Association International Conference.
• Samuel Guzman, Saman Hazany. Spatial Transcriptomics on En Bloc Hippocampal Resections from Adult-Onset Drug Resistant Mesial Temporal Lobe Epilepsy Hippocampal Sclerosis. American Association of Neuropathology. 2023.
• Samuel Guzman, John Ringman. Neuropathology of the Jalisco A431E PSEN1 Mutation in Comparison to Other PSEN1 Mutations in Autosomal Dominant Alzheimer’s Disease. American Association of Neuropathology. 2023.
• B.K DeMasters, S. Guzman. D. Ormond. More unusual features in H3 K27M-mutant gliomas. Society of Neurooncology.
• D Ormond, S. Guzman, B.K. DeMasters. Infratentorial IDH-mutant astrocytomas require high index of suspicion for adequate diagnosis. Society of Neurooncology. 2023.
• Vassantachart A, Cao Y, Shen Z, Cheng K, Gribble M, Ye JC, Zada G, Hurth K, Mathew A, Guzman S, Yang W. A repository of grade 1 and 2 meningioma MRIs in a public dataset for radiomics reproducibility tests. Med Phys. 2023 Oct 10. doi: 10.1002/mp.16763. Epub ahead of print. PMID: 37815256.
• Guzman S, Kleinschmidt-DeMasters BK. Pathology of rheumatoid meningitis: A report of 5 cases highlighting the importance of clinical correlation. Ann Diagn Pathol. 2025 Feb;74:152412. PubMed PMID: 39608293
• Saternos H, Hamlett ED, Guzman S, Head E, Granholm AC, Ledreux A. Unique Pathology in the Locus Coeruleus of Individuals with Down Syndrome. J Alzheimers Dis. 2024;101(2):541-561. PubMed PMID: 39213062
• Colvett I, Gilmore A, Guzman S, Ledreux A, Quintero JE, Ginjupally DR, Gurwell JA, Slevin JT, Guduru Z, Gerhardt GA, van Horne CG, Granholm AC. Recipient Reaction and Composition of Autologous Sural Nerve Tissue Grafts into the Human Brain. J Clin Med. 2023 Sep 22;12(19):6121. doi: 10.3390/jcm12196121. PMID: 37834764; PMCID: PMC10573749.
• Ringman JM, Dorrani N, Fernández SG, Signer R, Martinez-Agosto J, Lee H, Douine ED, Qiao Y, Shi Y, D'Orazio L, Pawar S, Robbie L, Kashani AH, Singer M, Byers JT, Magaki S, Guzman S, Sagare A, Zlokovic B, Cederbaum S, Nelson S, Sheikh-Bahaei N, Chui HC, Chávez-Gutiérrez L, Vinters HV. Characterization of spastic paraplegia in a family with a novel PSEN1 mutation. Brain Commun. 2023 Feb 15;5(2):fcad030. doi: 10.1093/braincomms/fcad030. PMID: 36895955; PMCID: PMC9991506.
• Granholm AE, Englund E, Gilmore A, Head E, Yong WH, Perez SE, Guzman SJ, Hamlett ED, Mufson EJ. Neuropathological findings in Down syndrome, Alzheimer's disease and control patients with and without SARS-COV-2: preliminary findings. Acta Neuropathol. 2024 May 27;147(1):92. PubMed PMID: 38801558
• Aldecoa I, Barroeta I, Carroll SL, Fortea J, Gilmore A, Ginsberg SD, Guzman SJ, Hamlett ED, Head E, Perez SE, Potter H, Molina-Porcel L, Raha-Chowdhury R, Wisniewski T, Yong WH, Zaman S, Ghosh S, Mufson EJ, Granholm AC. Down Syndrome Biobank Consortium: A perspective. Alzheimers Dement. 2024 Mar;20(3):2262-2272. PubMed PMID: 38270275
• Vassantachart A, Cao Y, Shen Z, Cheng K, Gribble M, Ye JC, Zada G, Hurth K, Mathew A, Guzman S, Yang W. A repository of grade 1 and 2 meningioma MRIs in a public dataset for radiomics reproducibility tests. Med Phys. 2024 Mar;51(3):2334-2344. PubMed PMID: 37815256
• Iban Aldecoa1, Isabel Barroeta, Steven Carroll, Juan Fortea, Anah Gilmore, Stephen Ginsberg, Samuel Guzman, Eric D. Hamlett, Elizabeth Head, Elliott J. Mufson, Sylvia Perez, Huntington Potter, Laura Molina-Porcel, Ruma Raha-Chowdhury, Thomas Wisniewski, William H. Yong, Shahid Zaman, Ann-Charlotte Granholm, and the Down syndrome Biobank Consortium. The Down Syndrome Biobank Consortium: A perspective. Alzheimer’s and Dementia. Accepted manuscript
• Samuel Guzman, MD, Sarah Edminster, DO, Yonghua Zhuang, PhD, Schuyler Lee PhD, An Doan PhD, Bifeng Gao PhD, Nakul Shankar, MD, Ann-Charlotte Granholm, Phd/DDS, Gilsoon Park, PhD, Ho Sung Kim, PhD, Jitin Makkar, MD, Josh Byers, MD, Jonathan J. Russin, MD, Charles Liu, MD, Saman Hazany, MD. Spatial Transcriptomics, Histopathology, and Magnetic Resonance Subfield Segmentation of the Hippocampus of an Adult with Drug Resistant Epilepsy and Hippocampal Sclerosis. Submitted

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Specialty Information

Specialties

• Neuropathology