Benjamin Click, MD

Professional Titles

• Assistant Professor of Medicine

Research Interests

Publications

• Hollis RH, Smith N, Sapci I, Click B, Regueiro M, Hull TL, Lightner AL. Small Bowel Crohn's Disease Recurrence is Common After Total Proctocolectomy for Crohn's Colitis. Dis Colon Rectum. 2022 Mar 1;65(3):390-398. PubMed PMID: 34759246
• Anderson A, Cherfane C, Click B, Ramos-Rivers C, Koutroubakis IE, Hashash JG, Babichenko D, Tang G, Dunn M, Barrie A, Proksell S, Dueker J, Johnston E, Schwartz M, Binion DG. Monocytosis Is a Biomarker of Severity in Inflammatory Bowel Disease: Analysis of a 6-Year Prospective Natural History Registry. Inflamm Bowel Dis. 2022 Jan 5;28(1):70-78. PubMed PMID: 33693659
• Garg R, Mohammed A, Singh A, Regueiro M, Click B. Trends and Outcomes of Acute Diverticulitis in Inflammatory Bowel Disease: A Propensity-matched National Study. Inflamm Bowel Dis. 2022 Jan 5;28(1):48-53. PubMed PMID: 33528011
• Faisal MS, Burke CA, Liska D, Lightner AL, Leach B, O'Malley M, LaGuardia L, Click B, Achkar JP, Kalady M, Church JM, Mankaney G. Association of cancer with comorbid inflammatory conditions and treatment in patients with Lynch syndrome. World J Clin Oncol. 2022 Jan 24;13(1):49-61. PubMed PMID: 35116232
• Holubar SD, Gunter RL, Click BH, Achkar JP, Lightner AL, Lipman JM, Hull TL, Regueiro M, Rieder F, Steele SR. Mesenteric Excision and Exclusion for Ileocolic Crohn's Disease: Feasibility and Safety of an Innovative, Combined Surgical Approach With Extended Mesenteric Excision and Kono-S Anastomosis. Dis Colon Rectum. 2022 Jan 1;65(1):e5-e13. PubMed PMID: 34882636
• Lightner AL, Steele SR, McMichael JP, Jia X, Qazi T, Click BH, Church J. Pouch Function Over Time and With Advancing Age. Dis Colon Rectum. 2022 Feb 1;65(2):254-263. PubMed PMID: 34459447
• Click B, Merchea A, Colibaseanu DT, Regueiro M, Farraye FA, Stocchi L. Ileocolic Resection for Crohn Disease: The Influence of Different Surgical Techniques on Perioperative Outcomes, Recurrence Rates, and Endoscopic Surveillance. Inflamm Bowel Dis. 2022 Feb 1;28(2):289-298. PubMed PMID: 33988234
• Garg R, Mohan BP, Ponnada S, Regueiro M, Lightner AL, Click B. Postoperative outcomes after preoperative ustekinumab exposure in patients with Crohn's disease: a systematic review and meta-analysis. Ann Gastroenterol. 2021 Sep-Oct;34(5):691-698. PubMed PMID: 34475740
• El Ouali S, Baker ME, Lyu R, Fletcher JG, Bruining DH, Holubar SD, Click B, Qazi T, Cohen BL, Rieder F. Validation of stricture length, duration and obstructive symptoms as predictors for intervention in ileal stricturing Crohn's disease. United European Gastroenterol J. 2022 Nov;10(9):958-972. PubMed PMID: 36479841
• Johnson AM, Barsky M, Ahmed W, Zullow S, Galati J, Jairath V, Narula N, Peerani F, Click BH, Coburn ES, Dang TT, Gold S, Agrawal M, Garg R, Aggarwal M, Mohammad D, Halloran B, Kochhar GS, Todorowski H, Ud Din NM, Izanec J, Teeple A, Gasink C, Muser E, Ding Z, Swaminath A, Lakhani K, Hogan D, Datta S, Ungaro RC, Boland BS, Bohm M, Fischer M, Sagi S, Afzali A, Ullman T, Lawlor G, Baumgart DC, Chang S, Hudesman D, Lukin D, Scherl EJ, Colombel JF, Sands BE, Siegel CA, Regueiro M, Sandborn WJ, Bruining D, Kane S, Loftus EV Jr, Dulai PS. The Real-World Effectiveness and Safety of Ustekinumab in the Treatment of Crohn's Disease: Results From the SUCCESS Consortium. Am J Gastroenterol. 2022 Nov 23. [Epub ahead of print] PubMed PMID: 36191274
• Lightner AL, Vaidya P, McMichael J, Click B, Regueiro M, Steele SR, Hull TL. Anal Squamous Cell Carcinoma in Ulcerative Colitis: Can Pouches Withstand Traditional Treatment Protocols?. Dis Colon Rectum. 2021 Sep 1;64(9):1106-1111. PubMed PMID: 33951686
• Axelrad JE, Li T, Bachour SP, Nakamura TI, Shah R, Sachs MC, Chang S, Hudesman DP, Holubar SD, Lightner AL, Barnes EL, Cohen BL, Rieder F, Esen E, Remzi F, Regueiro M, Click B. Early Initiation of Antitumor Necrosis Factor Therapy Reduces Postoperative Recurrence of Crohn's Disease Following Ileocecal Resection. Inflamm Bowel Dis. 2022 Jul 29. [Epub ahead of print] PubMed PMID: 35905032
• Aggarwal M, Garg R, Parthasarthy G, Nowacki AS, Padival R, McCullough A, Qazi T, Click B, Rieder F, Cohen BL. Crohn's Disease Is Associated with Liver Fibrosis in Patients with Nonalcoholic Fatty Liver Disease. Dig Dis Sci. 2022 Jun 22. [Epub ahead of print] PubMed PMID: 35731428
• Sleiman J, Hitawala AA, Cohen B, Falloon K, Simonson M, Click B, Khanna U, Fernandez AP, Rieder F. Systematic Review: Sweet Syndrome Associated with Inflammatory Bowel Disease. J Crohns Colitis. 2021 Nov 8;15(11):1864-1876. PubMed PMID: 33891004
• Bachour SP, Shah RS, Rieder F, Qazi T, Achkar JP, Philpott J, Lashner B, Holubar SD, Lightner AL, Barnes EL, Axelrad J, Regueiro M, Click B, Cohen BL. Intra-abdominal septic complications after ileocolic resection increases risk for endoscopic and surgical postoperative Crohn's disease recurrence. J Crohns Colitis. 2022 Nov 23;16(11):1696-1705. PubMed PMID: 35705188
• Lightner AL, Sklow B, Click B, Regueiro M, McMichael JJ, Jia X, Vaidya P, Delaney CP, Cohen B, Wexner SD, Steele SR, Holubar SD. Venous Thromboembolism in Admitted Patients with Inflammatory Bowel Disease: An Enterprise-Wide Experience of 86,000 Hospital Encounters. Dis Colon Rectum. 2022 Mar 24. [Epub ahead of print] PubMed PMID: 35333791
• Bachour SP, Shah RS, Lyu R, Rieder F, Qazi T, Lashner B, Achkar JP, Philpott J, Barnes EL, Axelrad J, Holubar SD, Lightner AL, Regueiro M, Cohen BL, Click BH. Mild neoterminal ileal post-operative recurrence of Crohn's disease conveys higher risk for severe endoscopic disease progression than isolated anastomotic lesions. Aliment Pharmacol Ther. 2022 May;55(9):1139-1150. PubMed PMID: 35285534
• Click B, Barnes EL, Cohen BL, Sands BE, Hanson JS, Rubin DT, Dubinsky MC, Regueiro M, Gazis D, Crawford JM, Long MD. Objective disease activity assessment and therapeutic drug monitoring prior to biologic therapy changes in routine inflammatory bowel disease clinical practice: TARGET-IBD. BMC Gastroenterol. 2022 Feb 19;22(1):71. PubMed PMID: 35183108
• Bachour SP, Baker ME, Click B. Reply. Clin Gastroenterol Hepatol. 2022 Dec;20(12):2925-2926. PubMed PMID: 35149221
• Faisal MS, Burke CA, Liska D, Lightner AL, Leach B, O'Malley M, LaGuardia L, Click B, Achkar JP, Kalady M, Church JM, Mankaney G. Association of cancer with comorbid inflammatory conditions and treatment in patients with Lynch syndrome. World J Clin Oncol. 2022 Jan 24;13(1):49-61. PubMed PMID: 35116232
• Bachour SP, Shah RS, Lyu R, Nakamura T, Shen M, Li T, Dane B, Barnes EL, Rieder F, Cohen B, Qazi T, Lashner B, Achkar JP, Philpott J, Holubar SD, Lightner AL, Regueiro M, Axelrad J, Baker ME, Click B. Test Characteristics of Cross-sectional Imaging and Concordance With Endoscopy in Postoperative Crohn's Disease. Clin Gastroenterol Hepatol. 2022 Oct;20(10):2327-2336.e4. PubMed PMID: 34968729
• Shah RS, Bachour S, Jia X, Holubar SD, Hull TL, Achkar JP, Philpott J, Qazi T, Rieder F, Cohen BL, Regueiro MD, Lightner AL, Click BH. Hypoalbuminaemia, Not Biologic Exposure, Is Associated with Postoperative Complications in Crohn's Disease Patients Undergoing Ileocolic Resection. J Crohns Colitis. 2021 Jul 5;15(7):1142-1151. PubMed PMID: 33388775
• Holubar SD, Gunter RL, Click BH, Achkar JP, Lightner AL, Lipman JM, Hull TL, Regueiro M, Rieder F, Steele SR. Mesenteric Excision and Exclusion for Ileocolic Crohn's Disease: Feasibility and Safety of an Innovative, Combined Surgical Approach With Extended Mesenteric Excision and Kono-S Anastomosis. Dis Colon Rectum. 2022 Jan 1;65(1):e5-e13. PubMed PMID: 34882636
• Hollis RH, Smith N, Sapci I, Click B, Regueiro M, Hull TL, Lightner AL. Small Bowel Crohn's Disease Recurrence is Common After Total Proctocolectomy for Crohn's Colitis. Dis Colon Rectum. 2022 Mar 1;65(3):390-398. PubMed PMID: 34759246
• Shah RS, Click BH. Medical therapies for postoperative Crohn's disease. Therap Adv Gastroenterol. 2021;14:1756284821993581. PubMed PMID: 33643440
• Garg R, Mohan BP, Ponnada S, Singh A, Aminian A, Regueiro M, Click B. Safety and Efficacy of Bariatric Surgery in Inflammatory Bowel Disease Patients: a Systematic Review and Meta-analysis. Obes Surg. 2020 Oct;30(10):3872-3883. PubMed PMID: 32578179
• Click B, Lopez R, Arrigain S, Schold J, Regueiro M, Rizk M. Shifting Cost-drivers of Health Care Expenditures in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2020 Jul 17;26(8):1268-1275. PubMed PMID: 31671186
• Khoudari G, Mansoor E, Click B, Alkhayyat M, Saleh MA, Sinh P, Katz J, Cooper GS, Regueiro M. Rates of Intestinal Resection and Colectomy in Inflammatory Bowel Disease Patients After Initiation of Biologics: A Cohort Study. Clin Gastroenterol Hepatol. 2022 May;20(5):e974-e983. PubMed PMID: 33065311
• Beard JA, Click BH. The burden of cost in inflammatory bowel disease: a medical economic perspective. Curr Opin Gastroenterol. 2020 Jul;36(4):310-316. PubMed PMID: 32398566
• Franco DL, Click B. Proactive Versus Reactive Therapeutic Drug Monitoring of Infliximab in Crohn's Disease: Is the Juice Worth the Squeeze?. Inflamm Bowel Dis. 2020 Jan 1;26(1):112-113. PubMed PMID: 31184363
• Shah RS, Bachour S, Jia X, Holubar SD, Hull TL, Achkar JP, Philpott J, Qazi T, Rieder F, Cohen BL, Regueiro MD, Lightner AL, Click BH. Hypoalbuminaemia, Not Biologic Exposure, Is Associated with Postoperative Complications in Crohn's Disease Patients Undergoing Ileocolic Resection. J Crohns Colitis. 2021 Jul 5;15(7):1142-1151. PubMed PMID: 33388775
• Garg R, Mohammed A, Singh A, Regueiro M, Click B. Trends and Outcomes of Acute Diverticulitis in Inflammatory Bowel Disease: A Propensity-matched National Study. Inflamm Bowel Dis. 2022 Jan 5;28(1):48-53. PubMed PMID: 33528011
• Lightner AL, Click B, Yamamoto T, Spinelli A, Kotze P. Management of Isolated Anal Strictures in Crohn's Disease. Dis Colon Rectum. 2020 Dec;63(12):1639-1647. PubMed PMID: 33149025
• Shah RS, Click BH. Medical therapies for postoperative Crohn's disease. Therap Adv Gastroenterol. 2021;14:1756284821993581. PubMed PMID: 33643440
• El Ouali S, Click B, Holubar SD, Rieder F. Natural history, diagnosis and treatment approach to fibrostenosing Crohn's disease. United European Gastroenterol J. 2020 Apr;8(3):263-270. PubMed PMID: 32213020
• Anderson A, Cherfane C, Click B, Ramos-Rivers C, Koutroubakis IE, Hashash JG, Babichenko D, Tang G, Dunn M, Barrie A, Proksell S, Dueker J, Johnston E, Schwartz M, Binion DG. Monocytosis Is a Biomarker of Severity in Inflammatory Bowel Disease: Analysis of a 6-Year Prospective Natural History Registry. Inflamm Bowel Dis. 2022 Jan 5;28(1):70-78. PubMed PMID: 33693659
• Faisal MS, Burke CA, Achkar JP, Click B, O'Malley M, LaGuardia L, Milicia S, Leach B, Liska D, Church J, Kalady M, Mankaney G. Malignancy risk in individuals with familial adenomatous polyposis receiving biologics and immunomodulators. Fam Cancer. 2022 Apr;21(2):189-195. PubMed PMID: 33822277
• Sleiman J, Hitawala AA, Cohen B, Falloon K, Simonson M, Click B, Khanna U, Fernandez AP, Rieder F. Systematic Review: Sweet Syndrome Associated with Inflammatory Bowel Disease. J Crohns Colitis. 2021 Nov 8;15(11):1864-1876. PubMed PMID: 33891004
• Click B, Regueiro M. The Inflammatory Bowel Disease Medical Home: From Patients to Populations. Inflamm Bowel Dis. 2019 Nov 14;25(12):1881-1885. PubMed PMID: 30934057
• Lightner AL, Vaidya P, McMichael J, Click B, Regueiro M, Steele SR, Hull TL. Anal Squamous Cell Carcinoma in Ulcerative Colitis: Can Pouches Withstand Traditional Treatment Protocols?. Dis Colon Rectum. 2021 Sep 1;64(9):1106-1111. PubMed PMID: 33951686
• Ma C, Jairath V, Click B, Hirota SA, Lu C, Parker CE, Rieder F. Targeting anti-fibrotic pathways in Crohn's disease - The final frontier?. Best Pract Res Clin Gastroenterol. 2019 Feb - Apr;38-39:101603. PubMed PMID: 31327400
• Lightner AL, Regueiro M, Click B. Special Considerations for Colorectal Surgery in the Elderly IBD Patient. Curr Treat Options Gastroenterol. 2019 Dec;17(4):449-456. PubMed PMID: 31755072
• Click B, Merchea A, Colibaseanu DT, Regueiro M, Farraye FA, Stocchi L. Ileocolic Resection for Crohn Disease: The Influence of Different Surgical Techniques on Perioperative Outcomes, Recurrence Rates, and Endoscopic Surveillance. Inflamm Bowel Dis. 2022 Feb 1;28(2):289-298. PubMed PMID: 33988234
• Click B, Regueiro M. A Practical Guide to the Safety and Monitoring of New IBD Therapies. Inflamm Bowel Dis. 2019 Apr 11;25(5):831-842. PubMed PMID: 30312391
• Anderson A, Ferris LK, Click B, Ramos-Rivers C, Koutroubakis IE, Hashash JG, Dunn M, Barrie A, Schwartz M, Regueiro M, Binion DG. Low Rates of Dermatologic Care and Skin Cancer Screening Among Inflammatory Bowel Disease Patients. Dig Dis Sci. 2018 Oct;63(10):2729-2739. PubMed PMID: 29713987
• Garg R, Aggarwal M, Butler R, Achkar JP, Lashner B, Philpott J, Cohen B, Qazi T, Rieder F, Regueiro M, Click B. Real-World Effectiveness and Safety of Ustekinumab in Elderly Crohn's Disease Patients. Dig Dis Sci. 2022 Jul;67(7):3138-3147. PubMed PMID: 34160735
• Regueiro M, Click B, Anderson A, Shrank W, Kogan J, McAnallen S, Szigethy E. Reduced Unplanned Care and Disease Activity and Increased Quality of Life After Patient Enrollment in an Inflammatory Bowel Disease Medical Home. Clin Gastroenterol Hepatol. 2018 Nov;16(11):1777-1785. PubMed PMID: 29654918
• Click B, Pinsky PF, Hickey T, Doroudi M, Schoen RE. Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence. JAMA. 2018 May 15;319(19):2021-2031. PubMed PMID: 29800214
• Anderson A, Click B, Ramos-Rivers C, Koutroubakis IE, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A 3rd, Regueiro M, Binion DG. The Association Between Sustained Poor Quality of Life and Future Opioid Use in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2018 Jun 8;24(7):1380-1388. PubMed PMID: 29860492
• Gajendran M, Bauer AJ, Buchholz BM, Watson AR, Koutroubakis IE, Hashash JG, Ramos-Rivers C, Shah N, Lee KK, Cruz RJ, Regueiro M, Zuckerbraun B, Schwartz M, Swoger J, Barrie A, Harrison J, Hartman DJ, Salgado J, Rivers WM, Click B, Anderson AM, Umapathy C, Babichenko D, Dunn MA, Binion DG. Ileocecal Anastomosis Type Significantly Influences Long-Term Functional Status, Quality of Life, and Healthcare Utilization in Postoperative Crohn's Disease Patients Independent of Inflammation Recurrence. Am J Gastroenterol. 2018 Apr;113(4):576-583. PubMed PMID: 29610509
• Lightner AL, Steele SR, McMichael JP, Jia X, Qazi T, Click BH, Church J. Pouch Function Over Time and With Advancing Age. Dis Colon Rectum. 2022 Feb 1;65(2):254-263. PubMed PMID: 34459447
• Click B, Anderson AM, Ramos Rivers C, Koutroubakis IE, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A 3rd, Szigethy E, Regueiro M, Schoen RE, Binion DG. Telephone Encounters Predict Future High Financial Expenditures in Inflammatory Bowel Disease Patients: A 3-Year Prospective Observational Study. J Clin Gastroenterol. 2018 Apr;52(4):319-325. PubMed PMID: 28452828
• Garg R, Mohan BP, Ponnada S, Regueiro M, Lightner AL, Click B. Postoperative outcomes after preoperative ustekinumab exposure in patients with Crohn's disease: a systematic review and meta-analysis. Ann Gastroenterol. 2021 Sep-Oct;34(5):691-698. PubMed PMID: 34475740
• Click BH, Greer JB, Regueiro MD, Hartman DJ, Davis PL, Siegel CA, Herfarth HH, Rosh JR, Shah SA, Koltun WA, Binion DG, Baidoo L, Szigethy E. IBD LIVE Series-Case 7: The Brain-Gut Connection and the Importance of Integrated Care in IBD. Inflamm Bowel Dis. 2017 May;23(5):681-694. PubMed PMID: 28426450
• Bachour SP, Shah RS, Joseph A, Syed H, Ali AH, Rieder F, Barnes EL, Axelrad J, Holubar SD, Regueiro M, Cohen BL, Click BH. Change in Biologic Class Promotes Endoscopic Remission Following Endoscopic Postoperative Crohn's Disease Recurrence. J Clin Gastroenterol. 2023 Nov 27. [Epub ahead of print] PubMed PMID: 38019054
• Taylor AL, Kogan J, Meyers J, Lupe S, Click B, Cohen B, Szigethy E, Keefer L, Nikolajski C. Perceptions of and Experiences with the COVID-19 Pandemic Among Individuals with Inflammatory Bowel Disease. J Clin Psychol Med Settings. 2023 Nov 6. [Epub ahead of print] PubMed PMID: 37932518
• Click B, Binion DG, Anderson AM. Predicting Costs of Care for Patients With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2017 Mar;15(3):393-395. PubMed PMID: 27923719
• Shah RS, Bachour S, Joseph A, Xiao H, Lyu R, Syed H, Li T, Pothula S, Vinaithirthan V, Ali AH, Contreras S, Hu JH, Barnes EL, Axelrad JE, Holubar SD, Regueiro M, Cohen BL, Click BH. Real-World Surgical and Endoscopic Recurrence Based on Risk Profiles and Prophylaxis Utilization in Postoperative Crohn's Disease. Clin Gastroenterol Hepatol. 2023 Oct 23. [Epub ahead of print] PubMed PMID: 37879523
• Li T, Click B, Bachour S, Sachs M, Barnes EL, Cohen BL, Contreras S, Axelrad J. Suboptimal Guideline Adherence and Biomarker Underutilization in Monitoring of Post-operative Crohn's Disease. Dig Dis Sci. 2023 Sep;68(9):3596-3604. PubMed PMID: 37548896
• Garg R, Aggarwal M, Mohammed A, Achkar JP, Lashner B, Philpott J, Cohen B, Qazi T, Rieder F, Regueiro M, Click B. Real-world effectiveness and safety of ustekinumab and vedolizumab in elderly patients with Crohn's disease. Indian J Gastroenterol. 2023 Oct;42(5):718-723. PubMed PMID: 37523059
• Bhat S, Click B, Regueiro M. Safety and Monitoring of Inflammatory Bowel Disease Advanced Therapies. Inflamm Bowel Dis. 2023 Jul 14. [Epub ahead of print] PubMed PMID: 37450619
• Rao BB, Click BH, Koutroubakis IE, Ramos Rivers C, Regueiro M, Swoger J, Schwartz M, Hashash J, Barrie A, Dunn MA, Binion DG. The Cost of Crohn's Disease: Varied Health Care Expenditure Patterns Across Distinct Disease Trajectories. Inflamm Bowel Dis. 2017 Jan;23(1):107-115. PubMed PMID: 27930405
• Bachour SP, Khan MZ, Shah RS, Joseph A, Syed H, Ali AH, Rieder F, Holubar SD, Barnes EL, Axelrad J, Regueiro M, Cohen BL, Click BH. Anastomotic Configuration and Temporary Diverting Ileostomy Do Not Increase Risk of Anastomotic Stricture in Postoperative Crohn's Disease. Am J Gastroenterol. 2023 Dec 1;118(12):2212-2219. PubMed PMID: 37410924
• Sleiman J, Patel M, Khan MZ, Falloon K, Cohen B, Click B, Khanna U, Fernandez AP, Rieder F. Sweet Syndrome Associated with Active Inflammatory Bowel Disease: A Case Series of a Rare Extra-intestinal Manifestation. Dig Dis Sci. 2023 Sep;68(9):3562-3568. PubMed PMID: 37402983
• Powers JC, Cohen BL, Rieder F, Click BH, Lyu R, Westbrook K, Hull T, Holubar S, Regueiro MD, Qazi T. Preoperative Use of Multiple Advanced Therapies Is Not Associated With Endoscopic Inflammatory Pouch Diseases. Inflamm Bowel Dis. 2023 Apr 15. [Epub ahead of print] PubMed PMID: 37061838
• Johnson AM, Barsky M, Ahmed W, Zullow S, Galati J, Jairath V, Narula N, Peerani F, Click BH, Coburn ES, Dang TT, Gold S, Agrawal M, Garg R, Aggarwal M, Mohammad D, Halloran B, Kochhar GS, Todorowski H, Ud Din NM, Izanec J, Teeple A, Gasink C, Muser E, Ding Z, Swaminath A, Lakhani K, Hogan D, Datta S, Ungaro RC, Boland BS, Bohm M, Fischer M, Sagi S, Afzali A, Ullman T, Lawlor G, Baumgart DC, Chang S, Hudesman D, Lukin D, Scherl EJ, Colombel JF, Sands BE, Siegel CA, Regueiro M, Sandborn WJ, Bruining D, Kane S, Loftus EV Jr, Dulai PS. The Real-World Effectiveness and Safety of Ustekinumab in the Treatment of Crohn's Disease: Results From the SUCCESS Consortium. Am J Gastroenterol. 2023 Feb 1;118(2):317-328. PubMed PMID: 36191274
• Axelrad JE, Li T, Bachour SP, Nakamura TI, Shah R, Sachs MC, Chang S, Hudesman DP, Holubar SD, Lightner AL, Barnes EL, Cohen BL, Rieder F, Esen E, Remzi F, Regueiro M, Click B. Early Initiation of Antitumor Necrosis Factor Therapy Reduces Postoperative Recurrence of Crohn's Disease Following Ileocecal Resection. Inflamm Bowel Dis. 2023 Jun 1;29(6):888-897. PubMed PMID: 35905032
• Aggarwal M, Garg R, Parthasarthy G, Nowacki AS, Padival R, McCullough A, Qazi T, Click B, Rieder F, Cohen BL. Crohn's Disease Is Associated with Liver Fibrosis in Patients with Nonalcoholic Fatty Liver Disease. Dig Dis Sci. 2023 Mar;68(3):1006-1015. PubMed PMID: 35731428
• Click B, Anderson AM, Koutroubakis IE, Rivers CR, Babichenko D, Machicado JD, Hartman DJ, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A III, Wenzel SE, Regueiro M, Binion DG. Peripheral Eosinophilia in Patients With Inflammatory Bowel Disease Defines an Aggressive Disease Phenotype. Am J Gastroenterol. 2017 Dec;112(12):1849-1858. PubMed PMID: 29112200
• Anderson A, Click B, Ramos-Rivers C, Cheng D, Babichenko D, Koutroubakis IE, Hashash JG, Schwartz M, Swoger J, Barrie AM 3rd, Dunn MA, Regueiro M, Binion DG. Lasting Impact of Clostridium difficile Infection in Inflammatory Bowel Disease: A Propensity Score Matched Analysis. Inflamm Bowel Dis. 2017 Dec;23(12):2180-2188. PubMed PMID: 29084081
• Lightner AL, Sklow B, Click B, Regueiro M, McMichael JJ, Jia X, Vaidya P, Delaney CP, Cohen B, Wexner SD, Steele SR, Holubar SD. Venous Thromboembolism in Patients Admitted for IBD: An Enterprise-Wide Experience of 86,000 Hospital Encounters. Dis Colon Rectum. 2023 Mar 1;66(3):410-418. PubMed PMID: 35333791
• Regueiro M, Click B, Holder D, Shrank W, McAnallen S, Szigethy E. Constructing an Inflammatory Bowel Disease Patient-Centered Medical Home. Clin Gastroenterol Hepatol. 2017 Aug;15(8):1148-1153.e4. PubMed PMID: 28624253
• Koutroubakis IE, Ramos-Rivers C, Regueiro M, Koutroumpakis E, Click B, Schwartz M, Swoger J, Baidoo L, Hashash JG, Barrie A, Dunn MA, Binion DG. Five-Year Period Prevalence and Characteristics of Anemia in a Large US Inflammatory Bowel Disease Cohort. J Clin Gastroenterol. 2016 Sep;50(8):638-43. PubMed PMID: 26485103
• Bhattacharya A, Rao BB, Koutroubakis IE, Click B, Vargas EJ, Regueiro M, Schwartz M, Swoger JM, Babichenko D, Hartmann D, Rivers CR, Barrie A 3rd, Hashash JG, Dunn MA, Binion DG. Silent Crohn's Disease Predicts Increased Bowel Damage During Multiyear Follow-up: The Consequences of Under-reporting Active Inflammation. Inflamm Bowel Dis. 2016 Nov;22(11):2665-2671. PubMed PMID: 27753691
• Anderson AJ, Click B, Ramos-Rivers C, Babichenko D, Koutroubakis IE, Hartman DJ, Hashash JG, Schwartz M, Swoger J, Barrie AM 3rd, Dunn MA, Regueiro M, Binion DG. Development of an Inflammatory Bowel Disease Research Registry Derived from Observational Electronic Health Record Data for Comprehensive Clinical Phenotyping. Dig Dis Sci. 2016 Nov;61(11):3236-3245. PubMed PMID: 27619390
• Click B, Ramos Rivers C, Koutroubakis IE, Babichenko D, Anderson AM, Hashash JG, Dunn MA, Schwartz M, Swoger J, Baidoo L, Barrie A 3rd, Regueiro M, Binion DG. Demographic and Clinical Predictors of High Healthcare Use in Patients with Inflammatory Bowel Disease. Inflamm Bowel Dis. 2016 Jun;22(6):1442-9. PubMed PMID: 26950309
• Click B, Vargas EJ, Anderson AM, Proksell S, Koutroubakis IE, Ramos Rivers C, Hashash JG, Regueiro M, Watson A, Dunn MA, Schwartz M, Swoger J, Baidoo L, Barrie A 3rd, Binion DG. Silent Crohn's Disease: Asymptomatic Patients with Elevated C-reactive Protein Are at Risk for Subsequent Hospitalization. Inflamm Bowel Dis. 2015 Oct;21(10):2254-61. PubMed PMID: 26197446
• Koutroubakis IE, Ramos-Rivers C, Regueiro M, Koutroumpakis E, Click B, Schoen RE, Hashash JG, Schwartz M, Swoger J, Baidoo L, Barrie A, Dunn MA, Binion DG. Persistent or Recurrent Anemia Is Associated With Severe and Disabling Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2015 Oct;13(10):1760-6. PubMed PMID: 25862987
• Click B, Ketchum AM, Turner R, Whitcomb DC, Papachristou GI, Yadav D. The role of apheresis in hypertriglyceridemia-induced acute pancreatitis: A systematic review. Pancreatology. 2015 Jul-Aug;15(4):313-20. PubMed PMID: 25800175
• Aoto J, Click B. A Practical Approach to Subcutaneous Infliximab. Am J Gastroenterol. 2024 Nov 1;119(11):2151-2159. PubMed PMID: 39494918
• Koutroubakis IE, Ramos-Rivers C, Regueiro M, Koutroumpakis E, Click B, Schwartz M, Swoger J, Baidoo L, Hashash JG, Barrie A, Dunn MA, Binion DG. The Influence of Anti-tumor Necrosis Factor Agents on Hemoglobin Levels of Patients with Inflammatory Bowel Disease. Inflamm Bowel Dis. 2015 Jul;21(7):1587-93. PubMed PMID: 25933393
• Rao BB, Click B, Eid G, Codario RA. Management of Refractory Noninsulinoma Pancreatogenous Hypoglycemia Syndrome with Gastric Bypass Reversal: A Case Report and Review of the Literature. Case Rep Endocrinol. 2015;2015:384526. PubMed PMID: 26523235
• Click B, Cross RK, Regueiro M, Keefer L. The IBD Clinic of Tomorrow: Holistic, Patient-Centric, and Value-based Care. Clin Gastroenterol Hepatol. 2024 Jul 25. [Epub ahead of print] PubMed PMID: 39025251
• Click B, Holubar SD. Targeting the mesentery with surgery in ileocolic Crohn's disease: where do we stand?. Lancet Gastroenterol Hepatol. 2024 Sep;9(9):774-775. PubMed PMID: 39025099
• Shah RS, Hu JH, Bachour S, Joseph A, Syed H, Yang Q, Hajj Ali A, Li T, Contreras S, Pothula S, Vinaithirthan V, Regueiro M, Axelrad J, Barnes EL, Cohen BL, Click BH. Histologic Activity From Neoterminal Ileal Biopsies in Patients With Crohn's Disease in Endoscopic Remission is Associated With Postoperative Recurrence. Am J Gastroenterol. 2024 Jul 15. [Epub ahead of print] PubMed PMID: 39007494
• Joseph A, Bachour SP, Shah R, El Halabi J, Syed H, Lyu R, Cohen B, Rieder F, Achkar JP, Philpott J, Qazi T, Hull T, Lipman J, Wexner S, Holubar SD, Regueiro M, Click B. Postoperative Crohn's Disease Recurrence Risk and Optimal Biologic Timing After Temporary Diversion Following Ileocolic Resection. Inflamm Bowel Dis. 2024 Jun 6. [Epub ahead of print] PubMed PMID: 38842693
• Ahmad H, Click B, Morris HL, Crawford JM, Choi J, Long MD. Factors Predicting Loss of Remission in Crohn's Disease Patients in Endoscopic Remission in the Real World: Results From TARGET-IBD. J Clin Gastroenterol. 2024 May 22. [Epub ahead of print] PubMed PMID: 38829830
• Li T, Shah R, Click B, Cohen BL, Barnes E, Joseph A, Bachour S, Hu J, Contreras S, Li E, Axelrad J. American Gastroenterological Association-Proposed Fecal Calprotectin Cutoff of 50 ug/g is Associated With Endoscopic Recurrence in a Real-World Cohort of Patients With Crohn's Disease Post-ileocolic Resection. Crohns Colitis 360. 2024 Jan;6(1):otae016. PubMed PMID: 38525200
• Bachour SP, Click BH. Clinical Update on the Prevention and Management of Postoperative Crohn's Disease Recurrence. Curr Gastroenterol Rep. 2024 Feb;26(2):41-52. PubMed PMID: 38227128
• Bachour SP, Shah RS, Joseph A, Syed H, Ali AH, Rieder F, Barnes EL, Axelrad J, Holubar SD, Regueiro M, Cohen BL, Click BH. Change in Biologic Class Promotes Endoscopic Remission Following Endoscopic Postoperative Crohn's Disease Recurrence. J Clin Gastroenterol. 2024 Sep 1;58(8):810-817. PubMed PMID: 38019054
• Taylor AL, Kogan J, Meyers J, Lupe S, Click B, Cohen B, Szigethy E, Keefer L, Nikolajski C. Perceptions of and Experiences with the COVID-19 Pandemic Among Individuals with Inflammatory Bowel Disease. J Clin Psychol Med Settings. 2024 Jun;31(2):279-291. PubMed PMID: 37932518
• Shah RS, Bachour S, Joseph A, Xiao H, Lyu R, Syed H, Li T, Pothula S, Vinaithirthan V, Ali AH, Contreras S, Hu JH, Barnes EL, Axelrad JE, Holubar SD, Regueiro M, Cohen BL, Click BH. Real-World Surgical and Endoscopic Recurrence Based on Risk Profiles and Prophylaxis Utilization in Postoperative Crohn's Disease. Clin Gastroenterol Hepatol. 2024 Apr;22(4):847-857.e12. PubMed PMID: 37879523

Professional Memberships

• Crohn's Colitis Foundation, Professional Member
• American College of Gastroenterology, Member
• American Gastroenterological Association, Member
• European Crohn's and Colitis Organization, Member

Practice Locations

• University of Colorado Hospital

Specialty Information

• Gastroenterology, Board Certification (2018, 2018)
• Internal Medicine, Board Certification (2015, 2015)

• Digestive System - Inflammatory Bowel Disease (IBD): Crohn’s disease, ulcerative colitis, microscopic colitis
• Digestive System