Mark Mikkelsen, MD, MSCE

Professor, Medicine-Pulmonary Sciences & Critical Care


FacultyPhoto
Medical School
  • MD, University of Virginia School of Medicine (2002)
Graduate School
  • MSCE, University of Pennsylvania (2008)
Undergraduate School
  • BA, Colgate University (NY) (1996)
Internship
  • Hospital of the University of Pennsylvania (2003)
Residency
  • Hospital of the University of Pennsylvania, Internal Medicine (2005)
Fellowships
  • Hospital of the University of Pennsylvania, Pulmonary Disease and Critical Care Medicine (2008)
Department
Medicine-Pulmonary Sciences & Critical Care

Professional Titles

  • Associate Chief Medical Officer, Critical Care

Recognitions

  • Healthcare Heroes During the Covid-19 Pandemic, South Jersey Biz (2020)

Publications

  • Oh S, Mikkelsen ME, O'Connor M, Bowles KH. Why Sepsis Survivors Need an ICD-10 Code for "Sepsis Aftercare". Chest. 2022 Nov;162(5):979-981. PubMed PMID: 36344131
  • Agarwal A, Chen JT, Coopersmith CM, Denson JL, Dickert NW, Ferrante LE, Gershengorn HB, Gosine AD, Hayward BJ, Kaur N, Khan A, Lamberton C, Landsittel D, Lyons PG, Mikkelsen ME, Nadig NR, Pietropaoli AP, Poole BR, Viglianti EM, Sevransky JE. SWEAT ICU-An Observational Study of Physician Workload and the Association of Physician Outcomes in Academic ICUs. Crit Care Explor. 2022 Oct;4(10):e0774. PubMed PMID: 36259061
  • Haines KJ, Leggett N, Hibbert E, Hall T, Boehm LM, Bakhru RN, Bastin AJ, Butcher BW, Eaton TL, Harris W, Hope AA, Jackson J, Johnson A, Kloos JA, Korzick KA, Mactavish P, Meyer J, Montgomery-Yates A, Quasim T, Slack A, Wade D, Still M, Netzer G, Hopkins RO, Mikkelsen ME, Iwashyna TJ, McPeake J, Sevin CM. Patient and Caregiver-Derived Health Service Improvements for Better Critical Care Recovery. Crit Care Med. 2022 Dec 1;50(12):1778-1787. PubMed PMID: 36205494
  • Zakrajsek JK, Min SJ, Ho PM, Kiser TH, Kannappan A, Sottile PD, Allen RR, Althoff MD, Reynolds PM, Moss M, Burnham EL, Mikkelsen ME, Vandivier RW. Extracorporeal Membrane Oxygenation for Refractory Asthma Exacerbations With Respiratory Failure. Chest. 2023 Jan;163(1):38-51. PubMed PMID: 36191634
  • McPeake J, Boehm L, Hibbert E, Hauschildt K, Bakhru R, Bastin A, Butcher B, Eaton T, Harris W, Hope A, Jackson J, Johnson A, Kloos J, Korzick K, McCartney J, Meyer J, Montgomery-Yates A, Quasim T, Slack A, Wade D, Still M, Netzer G, Hopkins RO, Mikkelsen ME, Iwashyna T, Haines K, Sevin C. Modification of social determinants of health by critical illness and consequences of that modification for recovery: an international qualitative study. BMJ Open. 2022 Sep 27;12(9):e060454. PubMed PMID: 36167379
  • Roberts KJ, Silvestri JA, Klaiman T, Gutsche JT, Jablonski J, Fuchs BD, Kerlin MP, Mikkelsen ME. Well-Being Among Respiratory Therapists in an Academic Medical Center During the COVID-19 Pandemic. Respir Care. 2022 Dec;67(12):1588-1596. PubMed PMID: 35922070
  • Chesley CF, Lane-Fall MB, Panchanadam V, Harhay MO, Wani AA, Mikkelsen ME, Fuchs BD. Racial Disparities in Occult Hypoxemia and Clinically Based Mitigation Strategies to Apply in Advance of Technological Advancements. Respir Care. 2022 Dec;67(12):1499-1507. PubMed PMID: 35679133
  • O'Connor M, Kennedy EE, Hirschman KB, Mikkelsen ME, Deb P, Ryvicker M, Hodgson NA, Barrón Y, Stawnychy MA, Garren PA, Bowles KH. Improving transitions and outcomes of sepsis survivors (I-TRANSFER): a type 1 hybrid protocol. BMC Palliat Care. 2022 Jun 2;21(1):98. PubMed PMID: 35655168
  • Maley JH, Sandsmark DK, Trainor A, Bass GD, Dabrowski CL, Magdamo BA, Durkin B, Hayes MM, Schwartzstein RM, Stevens JP, Kaplan LJ, Mikkelsen ME, Lane-Fall MB. Six-Month Impairment in Cognition, Mental Health, and Physical Function Following COVID-19-Associated Respiratory Failure. Crit Care Explor. 2022 Apr;4(4):e0673. PubMed PMID: 35372848
  • Kerlin MP, Silvestri JA, Klaiman T, Gutsche JT, Jablonski J, Mikkelsen ME. Critical Care Clinician Wellness during the COVID-19 Pandemic: A Longitudinal Analysis. Ann Am Thorac Soc. 2022 Feb;19(2):329-331. PubMed PMID: 34398722
  • Chesley CF, Harhay MO, Small DS, Hanish A, Prescott HC, Mikkelsen ME. Hospital Readmission and Post-Acute Care Use After Intensive Care Unit Admissions: New ICU Quality Metrics?. J Intensive Care Med. 2022 Feb;37(2):168-176. PubMed PMID: 32912034
  • Stephens RS, Mikkelsen ME. Changes in Cancer Therapy After ICU Admission: The Long Arm of Delirium. Crit Care Med. 2024 Jan 1;52(1):160-162. PubMed PMID: 38095526
  • Zakrajsek JK, Min SJ, Ho PM, Kiser TH, Kannappan A, Sottile PD, Allen RR, Althoff MD, Reynolds PM, Moss M, Burnham EL, Mikkelsen ME, Vandivier RW. Extracorporeal Membrane Oxygenation for Refractory Asthma Exacerbations With Respiratory Failure. Chest. 2023 Jan;163(1):38-51. PubMed PMID: 36191634
  • Fuher AN, Young H, Mikkelsen ME. The Harm of Inappropriate Central Line Blood Cultures in Clinical Practice. JAMA Intern Med. 2024 Oct 21. [Epub ahead of print] PubMed PMID: 39432314
  • Hippensteel JA, Aggarwal NR, Mikkelsen ME. A New Era in Critical Care Trials: Linking ICU Practice to Long-Term Outcomes. Am J Respir Crit Care Med. 2024 Apr 1;209(7):782-784. PubMed PMID: 38387023
  • Stephens RS, Mikkelsen ME. Changes in Cancer Therapy After ICU Admission: The Long Arm of Delirium. Crit Care Med. 2024 Jan 1;52(1):160-162. PubMed PMID: 38095526
  • Zakrajsek JK, Min SJ, Ho PM, Kiser TH, Kannappan A, Sottile PD, Allen RR, Althoff MD, Reynolds PM, Moss M, Burnham EL, Mikkelsen ME, Vandivier RW. Extracorporeal Membrane Oxygenation for Refractory Asthma Exacerbations With Respiratory Failure. Chest. 2023 Jan;163(1):38-51. PubMed PMID: 36191634

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Specialty Information

Specialties
  • Pulmonary Disease and Critical Care Medicine
  • Internal Medicine, Board Certification (2005)
  • Pulmonary Disease, Board Certification (2008)
  • Critical Care Medicine, Board Certification (2009)
Clinical Interests
Sepsis, ARDS, respiratory failure

Care Philosophy
Dr. Mikkelsen's philosophy for patient care is to ensure that exceptional, compassionate care is delivered to critically ill patients and their family members through outstanding, multi-disciplinary teamwork, the application of evidence-based care, and systematic study to optimize our performance.