Mark Mikkelsen, MD, MSCE

Professional Titles

• Associate Chief Medical Officer, Critical Care

Recognitions

• Healthcare Heroes During the Covid-19 Pandemic, South Jersey Biz (2020)

Publications

• Bowles KH, Stawnychy MA, O'Connor M, Mikkelsen ME, Hodgson N, Sang E, You SB, Pitcher K, Song J, Oh S, Newman B, Garren P, Weiss C, Hirschman KB. Context and determinants for implementing a sepsis survivor care transition intervention reported from five health systems and home health agencies. Front Med (Lausanne). 2025;12:1632083. PubMed PMID: 41404587
• Hauschildt KE, Thornton JD, Brown C, Hope AA, Jain S, Valley TS, Aslakson RA, Carlton EF, Iwashyna TJ, Mikkelsen M, Boen C, Dzeng E, Falvey J, George N, Hotchkin D, Khandelwal N, Khatri UG, McPeake J, Nadig NR, Oyesanya TO, Amiri I, Ashana DC. A Research Agenda to Mitigate Racial and Ethnic Disparities in U.S. Critical Care Medicine: An Official American Thoracic Society Research Statement. Am J Respir Crit Care Med. 2025 Dec;211(12):2268-2288. PubMed PMID: 41324349
• Flaws D, Stewart JD, Haines KJ, Fraser JF, McAuley DF, Patterson SE, Hodgson CL, Andersen SK, Bagshaw SM, Bourne RS, Connolly B, Cove M, Dhesi J, Duncan S, Gould D, Hartley P, Higgins L, Hough CL, Kwizera A, Leggett N, Ni Lochlainn M, Lone NI, MacTavish P, Manthorpe J, Mocellin D, Mikkelsen ME, Parekh D, Rosa RG, Rowan K, Summers C, Sutt AL, Taylor SP, Teixeira C, Tronstad O, Wilcox ME, Wilson E, Winearls J, McPeake J. Greater recovery after critical illness (GRACE): a call to action to create a new roadmap for critical illness research. Thorax. 2025 Dec 15;81(1):13-21. PubMed PMID: 41093567
• Mikkelsen ME, Robba C. Oxygenation and Organ Function: The Timeless Quest to Preserve Function and Avoid Toxicity. Am J Respir Crit Care Med. 2025 Oct 10. [Epub ahead of print] PubMed PMID: 41072402
• Devlin JW, Mikkelsen ME. Melatonin Use in the ICU: Mind the (Evidence) Gaps. Crit Care Med. 2025 Sep 1;53(9):e1821-e1823. PubMed PMID: 40891930
• Kerlin MP, Mikkelsen ME. The Legacy of COVID-19 on Critical Care-Is There an Upside?. JAMA Netw Open. 2025 Aug 1;8(8):e2527452. PubMed PMID: 40853665
• Grush KA, Svoboda E, Dunbar PJ, Kannappan A, Perrodin J, Root MZ, Mikkelsen ME. Dyspnea Among Mechanically Ventilated Patients: A Systematic Review. Crit Care Med. 2025 Jun 1;53(6):e1282-e1291. PubMed PMID: 40227090
• Fuher AN, Young H, Mikkelsen ME. Clarifying Appropriate Use of Central Line Blood Cultures-Reply. JAMA Intern Med. 2025 Jun 1;185(6):743. PubMed PMID: 40193089
• Fuher AN, Young H, Mikkelsen ME. The Harm of Inappropriate Central Line Blood Cultures in Clinical Practice. JAMA Intern Med. 2024 Dec 1;184(12):1470-1471. PubMed PMID: 39432314
• Hippensteel JA, Aggarwal NR, Mikkelsen ME. A New Era in Critical Care Trials: Linking ICU Practice to Long-Term Outcomes. Am J Respir Crit Care Med. 2024 Apr 1;209(7):782-784. PubMed PMID: 38387023
• Stephens RS, Mikkelsen ME. Changes in Cancer Therapy After ICU Admission: The Long Arm of Delirium. Crit Care Med. 2024 Jan 1;52(1):160-162. PubMed PMID: 38095526
• Stephens RS, Mikkelsen ME. Changes in Cancer Therapy After ICU Admission: The Long Arm of Delirium. Crit Care Med. 2024 Jan 1;52(1):160-162. PubMed PMID: 38095526
• Fuher AN, Young H, Mikkelsen ME. The Harm of Inappropriate Central Line Blood Cultures in Clinical Practice. JAMA Intern Med. 2024 Oct 21. [Epub ahead of print] PubMed PMID: 39432314
• Hippensteel JA, Aggarwal NR, Mikkelsen ME. A New Era in Critical Care Trials: Linking ICU Practice to Long-Term Outcomes. Am J Respir Crit Care Med. 2024 Apr 1;209(7):782-784. PubMed PMID: 38387023
• Stephens RS, Mikkelsen ME. Changes in Cancer Therapy After ICU Admission: The Long Arm of Delirium. Crit Care Med. 2024 Jan 1;52(1):160-162. PubMed PMID: 38095526
• Zakrajsek JK, Min SJ, Ho PM, Kiser TH, Kannappan A, Sottile PD, Allen RR, Althoff MD, Reynolds PM, Moss M, Burnham EL, Mikkelsen ME, Vandivier RW. Extracorporeal Membrane Oxygenation for Refractory Asthma Exacerbations With Respiratory Failure. Chest. 2023 Jan;163(1):38-51. PubMed PMID: 36191634
• Zakrajsek JK, Min SJ, Ho PM, Kiser TH, Kannappan A, Sottile PD, Allen RR, Althoff MD, Reynolds PM, Moss M, Burnham EL, Mikkelsen ME, Vandivier RW. Extracorporeal Membrane Oxygenation for Refractory Asthma Exacerbations With Respiratory Failure. Chest. 2023 Jan;163(1):38-51. PubMed PMID: 36191634
• Zakrajsek JK, Min SJ, Ho PM, Kiser TH, Kannappan A, Sottile PD, Allen RR, Althoff MD, Reynolds PM, Moss M, Burnham EL, Mikkelsen ME, Vandivier RW. Extracorporeal Membrane Oxygenation for Refractory Asthma Exacerbations With Respiratory Failure. Chest. 2023 Jan;163(1):38-51. PubMed PMID: 36191634
• McPeake J, Boehm L, Hibbert E, Hauschildt K, Bakhru R, Bastin A, Butcher B, Eaton T, Harris W, Hope A, Jackson J, Johnson A, Kloos J, Korzick K, McCartney J, Meyer J, Montgomery-Yates A, Quasim T, Slack A, Wade D, Still M, Netzer G, Hopkins RO, Mikkelsen ME, Iwashyna T, Haines K, Sevin C. Modification of social determinants of health by critical illness and consequences of that modification for recovery: an international qualitative study. BMJ Open. 2022 Sep 27;12(9):e060454. PubMed PMID: 36167379
• Roberts KJ, Silvestri JA, Klaiman T, Gutsche JT, Jablonski J, Fuchs BD, Kerlin MP, Mikkelsen ME. Well-Being Among Respiratory Therapists in an Academic Medical Center During the COVID-19 Pandemic. Respir Care. 2022 Dec;67(12):1588-1596. PubMed PMID: 35922070
• Chesley CF, Lane-Fall MB, Panchanadam V, Harhay MO, Wani AA, Mikkelsen ME, Fuchs BD. Racial Disparities in Occult Hypoxemia and Clinically Based Mitigation Strategies to Apply in Advance of Technological Advancements. Respir Care. 2022 Dec;67(12):1499-1507. PubMed PMID: 35679133
• O'Connor M, Kennedy EE, Hirschman KB, Mikkelsen ME, Deb P, Ryvicker M, Hodgson NA, Barrón Y, Stawnychy MA, Garren PA, Bowles KH. Improving transitions and outcomes of sepsis survivors (I-TRANSFER): a type 1 hybrid protocol. BMC Palliat Care. 2022 Jun 2;21(1):98. PubMed PMID: 35655168
• Maley JH, Sandsmark DK, Trainor A, Bass GD, Dabrowski CL, Magdamo BA, Durkin B, Hayes MM, Schwartzstein RM, Stevens JP, Kaplan LJ, Mikkelsen ME, Lane-Fall MB. Six-Month Impairment in Cognition, Mental Health, and Physical Function Following COVID-19-Associated Respiratory Failure. Crit Care Explor. 2022 Apr;4(4):e0673. PubMed PMID: 35372848
• Kerlin MP, Silvestri JA, Klaiman T, Gutsche JT, Jablonski J, Mikkelsen ME. Critical Care Clinician Wellness during the COVID-19 Pandemic: A Longitudinal Analysis. Ann Am Thorac Soc. 2022 Feb;19(2):329-331. PubMed PMID: 34398722
• Chesley CF, Harhay MO, Small DS, Hanish A, Prescott HC, Mikkelsen ME. Hospital Readmission and Post-Acute Care Use After Intensive Care Unit Admissions: New ICU Quality Metrics?. J Intensive Care Med. 2022 Feb;37(2):168-176. PubMed PMID: 32912034
• Oh S, Mikkelsen ME, O'Connor M, Bowles KH. Why Sepsis Survivors Need an ICD-10 Code for "Sepsis Aftercare". Chest. 2022 Nov;162(5):979-981. PubMed PMID: 36344131
• Agarwal A, Chen JT, Coopersmith CM, Denson JL, Dickert NW, Ferrante LE, Gershengorn HB, Gosine AD, Hayward BJ, Kaur N, Khan A, Lamberton C, Landsittel D, Lyons PG, Mikkelsen ME, Nadig NR, Pietropaoli AP, Poole BR, Viglianti EM, Sevransky JE. SWEAT ICU-An Observational Study of Physician Workload and the Association of Physician Outcomes in Academic ICUs. Crit Care Explor. 2022 Oct;4(10):e0774. PubMed PMID: 36259061
• Haines KJ, Leggett N, Hibbert E, Hall T, Boehm LM, Bakhru RN, Bastin AJ, Butcher BW, Eaton TL, Harris W, Hope AA, Jackson J, Johnson A, Kloos JA, Korzick KA, Mactavish P, Meyer J, Montgomery-Yates A, Quasim T, Slack A, Wade D, Still M, Netzer G, Hopkins RO, Mikkelsen ME, Iwashyna TJ, McPeake J, Sevin CM. Patient and Caregiver-Derived Health Service Improvements for Better Critical Care Recovery. Crit Care Med. 2022 Dec 1;50(12):1778-1787. PubMed PMID: 36205494

Practice Locations

Specialty Information

• Pulmonary Disease and Critical Care Medicine
• Internal Medicine, Board Certification (2005)
• Pulmonary Disease, Board Certification (2008)
• Critical Care Medicine, Board Certification (2009)