Swati Ghosh, PhD
Research Instructor, Pediatrics-Gastroenterology, Hepatology and Nutrition
Professional Titles
- Research Instructor
Publications
- Ghosh S, Devereaux MW, Orlicky DJ, Sokol RJ. Publisher Correction: Pharmacologic inhibition of HNF4a prevents parenteral nutrition associated cholestasis in mice. Sci Rep. 2023 Jul 19; 13(1):11673. PMID: 37468479.
- Ghosh S, Devereaux MW, Anderson AL, El Kasmi KC, Sokol RJ. Stat3 role in the protective effect of FXR Agonist in parenteral nutrition-associated cholestasis. Hepatol Commun. 2023 03 01; 7(3):e0056. PMID: 36848082.
- Swati Ghosh, Michael W Devereaux,Aimee L Anderson,David J Orlicky, Ronald J Sokol. STAT3 SIGNALING MEDIATES FXR AGONIST PROTECTION IN ACUTE CHOLANGIOPATHY MOUSE MODEL 2023 (Hepatology Supp)
- Swati Ghosh, Michael W Devereaux,Aimee L Anderson,David J Orlicky, Ronald J Sokol. FXR AGONIST INDUCED INTESTINAL FGF15/19 REGULATES FXR SIGNALING IN LIVER IN LITHOCHOLIC ACID DIET-INDUCED ACUTE CHOLANGIOPATHY MOUSE MODEL. 2023 (Hepatology Supp)
- Swati Ghosh, Michael W Devereaux,Karim C El Kasmi,, Ronald J Sokol. CELL-SPECIFIC EXPRESSION OF HIF1a ENABLES FXR AGONIST-MEDIATED PROTECTION FROM PARENTERAL NUTRITION ASSOCIATED CHOLESTASIS. 2023 (Hepatology Supp)
- Swati Ghosh, Michael W Devereaux,Karim C El Kasmi,, Ronald J Sokol. EXPRESSION OF HIF1a, AND ITS REGULATION BY H19, ENABLES FXR AGONIST-MEDIATED PROTECTION FROM PARENTERAL NUTRITION-ASSOCIATED CHOLESTASIS IN A CELL-SPECIFIC MANNER . 2023
- Ghosh S, Thakur MK. Overproduction of mouse estrogen receptor alpha-ligand binding domain decreases bacterial growth. Mol Biol Rep. 2008 Dec;35(4):589-94. PubMed PMID: 17786586
- Ghosh S, Thakur MK. Tissue-specific expression of receptor-interacting protein in aging mouse. Age (Dordr). 2008 Dec;30(4):237-43. PubMed PMID: 19424847
- Ghosh S, Thakur MK. Interaction of estrogen receptor-alpha ligand binding domain with nuclear proteins of aging mouse brain. J Neurosci Res. 2009 Aug 15;87(11):2591-600. PubMed PMID: 19326447
- Ghosh S, Devereaux MW, Liu C, Sokol RJ. LRH-1 agonist DLPC through STAT6 promotes macrophage polarization and prevents parenteral nutrition-associated cholestasis in mice. Hepatology. 2024,1;79(5):986-1004.
- Swati Ghosh, Michael Devereaux, Aimee Anderson, David Orlicky, Ronald Sokol, MECHANISM OF STAT3 ROLE IN THE PROTECTIVE EFFECTS OF FXR AGONIST IN CHRONIC MOUSE MODEL OF INFLAMMATORY CHOLANGIOPATHY (Hepatology Suppl),2024
- Swati Ghosh, Michael Devereaux, Karim el kasmi, Ronald Sokol.MACROPHAGE-SPECIFIC HIF1a INHIBITION ACTIVATES HEPATIC STAT6 AND PROTECTS FROM PARENTERAL NUTRITION- ASSOCIATED CHOLESTASIS.2024 Hepatology Supply
- Swati Ghosh, Michael Devereaux,Aimee Anderson, Colin Anderson, Angelo D'Alesandror, David Orlicky, Ronald Sokol,MECHANISM OF LAURIC ACID-MEDIATED HEPATOBILIARY PROTECTION DURING ACUTE INFLAMMATORY CHOLANGIOPATHY IN MICE,2024 Hepatology Supply.
- Thakur MK, Ghosh S. Interaction of estrogen receptor alpha transactivation domain with MTA1 decreases in old mouse brain. J Mol Neurosci. 2009 Mar;37(3):269-73. PubMed PMID: 18679832
- Swati Ghosh, Michael Devereaux, Aimee Anderson, David Orlicky, Ronald Sokol, PROTECTIVE EFFECT OF FXR AGONIST IS MEDIATED THROUGH STAT3 ACTIVATION IN A CHRONIC MOUSE MODEL OF INFLAMMATORY CHOLANGIOPATHY ASSOCIATED WITH ELEVATED ARACHIDONIC ACID LEVELS 2024
- Ghosh S, Thakur MK. Interaction of estrogen receptor-alpha transactivation domain with nuclear proteins of mouse brain: p68 RNA helicase shows age- and sex-specific change. J Neurosci Res. 2009 May 1;87(6):1323-8. PubMed PMID: 19025768
- Ghosh S, Thakur MK. Age-dependent decrease in the interaction of beta-tubulin with estrogen receptor alpha transactivation domain in mouse brain. Neurosci Lett. 2009 Oct 30;464(3):218-21. PubMed PMID: 19715742
- Thakur MK, Ghosh S. GST-tagged mouse estrogen receptor alpha-transactivation domain fusion protein is specifically degraded during its over-expression in E. coli and purification. Mol Biol Rep. 2010 Mar;37(3):1335-40. PubMed PMID: 19319663
- Freudenberg JM, Ghosh S, Lackford BL, Yellaboina S, Zheng X, Li R, Cuddapah S, Wade PA, Hu G, Jothi R. Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity. Nucleic Acids Res. 2012 Apr;40(8):3364-77. PubMed PMID: 22210859
- Cinghu S, Yellaboina S, Freudenberg JM, Ghosh S, Zheng X, Oldfield AJ, Lackford BL, Zaykin DV, Hu G, Jothi R. Integrative framework for identification of key cell identity genes uncovers determinants of ES cell identity and homeostasis. Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):E1581-90. PubMed PMID: 24711389
- Jo JR, Lee SE, An S, Nedumaran B, Ghosh S, Park KG, Kim YD. Gluconeogenic signals regulate hepcidin gene expression via a CRBN-KLF15 axis. BMB Rep. 2021 Apr;54(4):221-226. PubMed PMID: 33795032
- Ghosh S, Devereaux MW, Anderson AL, Gehrke S, Reisz JA, D'Alessandro A, Orlicky DJ, Lovell M, El Kasmi KC, Shearn CT, Sokol RJ. NF-?B Regulation of LRH-1 and ABCG5/8 Potentiates Phytosterol Role in the Pathogenesis of Parenteral Nutrition-Associated Cholestasis. Hepatology. 2021 Dec;74(6):3284-3300. PubMed PMID: 34310734
- El Kasmi KC, Ghosh S, Anderson AL, Devereaux MW, Balasubramaniyan N, D'Alessandro A, Orlicky DJ, Suchy FJ, Shearn CT, Sokol RJ. Pharmacologic activation of hepatic farnesoid X receptor prevents parenteral nutrition-associated cholestasis in mice. Hepatology. 2022 Feb;75(2):252-265. PubMed PMID: 34387888
- El Kasmi KC, Vue PM, Anderson AL, Devereaux MW, Ghosh S, Balasubramaniyan N, Fillon SA, Dahrenmoeller C, Allawzi A, Woods C, McKenna S, Wright CJ, Johnson L, D'Alessandro A, Reisz JA, Nozik-Grayck E, Suchy FJ, Sokol RJ. Macrophage-derived IL-1ß/NF-?B signaling mediates parenteral nutrition-associated cholestasis. Nat Commun. 2018 Apr 11;9(1):1393. PubMed PMID: 29643332
- Jo JR, An S, Ghosh S, Nedumaran B, Kim YD. Growth hormone promotes hepatic gluconeogenesis by enhancing BTG2-YY1 signaling pathway. Sci Rep. 2021 Sep 23;11(1):18999. PubMed PMID: 34556771
- Ghosh S, Devereaux MW, Liu C, Sokol RJ. LRH-1 agonist DLPC through STAT6 promotes macrophage polarization and prevents parenteral nutrition associated cholestasis in mice. Hepatology. 2023 Nov 17. [Epub ahead of print] PubMed PMID: 37976384
- Ghosh S, Devereaux MW, Liu C, Sokol RJ. LRH-1 agonist DLPC through STAT6 promotes macrophage polarization and prevents parenteral nutrition associated cholestasis in mice. Hepatology. 2023 Nov 17. [Epub ahead of print] PubMed PMID: 37976384