Jordan Karlitz, MD

Clinical Professor, Medicine-Gastroenterology

FacultyPhoto
Medical School
  • MD, McGill University Faculty of Medicine (2000)
Undergraduate School
  • BA, University of California–Berkeley (CA)
Internship
  • New York Presbyterian Hospital (Columbia Campus) Program (2001)
Residency
  • New York Presbyterian Hospital (Columbia Campus) Program, Internal Medicine (2003)
Fellowships
  • Albert Einstein College of Medicine Program, Gastroenterology (2006)
Department
Medicine-Gastroenterology

Professional Titles

  • Gastroenterology/Hepatology Attending

Recognitions

  • Presidential Abstract Award, American College of Gastroenterology (2016)
    Pedigree Analysis Supports a Genotypic-phenotypic Correlation Between an AXIN2 Variant of Unknown Significance and Polyposis/Colorectal Cancer).
  • Governors' Award for Excellence in Clinical Research, American College of Gastroenterology (2014)
    Population-based Microsatellite Instability Testing in Young Colorectal Cancer Patients. Award given to the top 5 research submissions at the ACG annual meeting (selected by the ACG Educational Affairs Committee and Board of Governors)
  • DDW Poster of Distinction Award, American Gastroenterological Association (AGA) (2013)
    Colon cancer in the Acadian Parishes of Louisiana
  • American Gastroenterological Association, DDW, invited oral research presentation/plenary, AGA (2019)
    U.S. SEER Colorectal Cancer Incidence Rate Analysis in “High-Definition” One-Year Age Increments Supports Screening Prior to Age 50 and Reveals Geographic Disparities in Early-Onset Disease Development
  • American College of Gastroenterology Presidential Abstract/Poster Award, ACG (2021)
    Cost-Effectiveness of Outreach Strategies For Stool-Based Colorectal Cancer Screening in a Medicaid Population
  • American Journal of Gastroenterology (AJG), National Peer Reviewer of the Year, American College of Gastroenterology (2016)
    Ranked as the top scientific manuscript reviewer out of 600 reviewers nationwide for the AJG based on quality, volume and speed of reviews.
  • American College of Gastroenterology (ACG) Presidential Abstract/Poster Award, ACG (2023)
    Performance of Colon and Rectal Cancer Detection with a Multi-Cancer Early Detection (MCED) Blood Test
  • American College of Gastroenterology (ACG) Presidential Abstract/Poster Award, ACG (2023)
    Detection of Gastrointestinal Cancer in Individuals Without Clinical Suspicion of Cancer Using a Multi-Cancer Early Detection Blood Test in the PATHFINDER Study

Publications

  • Patel SG, Karlitz JJ, Yen T, Lieu CH, Boland CR. The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection. Lancet Gastroenterol Hepatol. 2022 Mar;7(3):262-274. PubMed PMID: 35090605
  • Patel SG, Karlitz JJ, Yen T, Lieu CH, Boland CR. Comparison of trends in early-onset colorectal cancer in North America and Europe - Authors' reply. Lancet Gastroenterol Hepatol. 2022 Jun;7(6):506. PubMed PMID: 35550052
  • Karlitz JJ, Fendrick AM, Bhatt J, Coronado GD, Jeyakumar S, Smith NJ, Plescia M, Brooks D, Limburg P, Lieberman D. Cost-Effectiveness of Outreach Strategies for Stool-Based Colorectal Cancer Screening in a Medicaid Population. Popul Health Manag. 2022 Jun;25(3):343-351. PubMed PMID: 34958279
  • Zhou M, Thompson TD, Lin HY, Chen VW, Karlitz JJ, Fontham ETH, Theall KP, Zhang L, Hsieh MC, Pollack LA, Wu XC. Impact of Relative Dose Intensity of FOLFOX Adjuvant Chemotherapy on Risk of Death Among Stage III Colon Cancer Patients. Clin Colorectal Cancer. 2022 Jun;21(2):e62-e75. PubMed PMID: 34756680
  • Yen T, Scolaro J, Montminy E, Karlitz JJ, Wani S, Patel SG. Spectrum of Advanced Colorectal Neoplasia and Anticipated Yield of Average-Risk Screening in Veterans Under Age 50. Clin Gastroenterol Hepatol. 2023 Mar;21(3):827-829.e3. PubMed PMID: 34800736
  • Stage-Stratified Incidence Rates of Colorectal Adenocarcinoma Among Patients Aged 46 to 49 in the United States. Montminy EM, Zhou M, Edelson JC, Karlitz JJ. JAMA Netw Open. 2024 Mar 4;7(3):e241848. doi: 10.1001/jamanetworkopen.2024.1848
  • A multi-cancer early detection blood test using machine learning detects early-stage cancers lacking USPSTF-recommended screening. Vittone J, Gill D, Goldsmith A, Klein EA, Karlitz JJ. NPJ Precis Oncol. 2024 Apr 17;8(1):91. doi: 10.1038/s41698-024-00568-z.
  • Montminy EM, Zhou M, Maniscalco L, Heda R, Kim MK, Patel SG, Wu XC, Itzkowitz SH, Karlitz JJ. Shifts in the Proportion of Distant Stage Early-Onset Colorectal Adenocarcinoma in the United States. Cancer Epidemiol Biomarkers Prev. 2022 Feb;31(2):334-341. PubMed PMID: 35082122
  • Fendrick AM, Fisher DA, Saoud L, Ozbay AB, Karlitz JJ, Limburg PJ. Impact of Patient Adherence to Stool-Based Colorectal Cancer Screening and Colonoscopy Following a Positive Test on Clinical Outcomes. Cancer Prev Res (Phila). 2021 Sep;14(9):845-850. PubMed PMID: 34021023
  • Karlitz JJ, Montminy EM, Itzkowitz SH. Adenocarcinomas, as Opposed to Carcinoids, Are Primarily Driving Increases in Early-Onset Colorectal Cancer Rates. Gastroenterology. 2021 Nov;161(5):1723-1724. PubMed PMID: 33753101
  • Shah ED, Amann ST, Karlitz JJ. Response to Tang, et al. Am J Gastroenterol. 2021 May 1;116(5):1087-1088. PubMed PMID: 33229984
  • Shah ED, Amann ST, Karlitz JJ. Response to Koulaouzidis, et al. Am J Gastroenterol. 2021 May 1;116(5):1089. PubMed PMID: 33229981
  • Adviento B, Conner M, Sarkisian A, Walano N, Andersson H, Karlitz J. Feasibility of Utilizing PREMM Score for Lynch Syndrome Identification in an Urban, Minority Patient Population. J Prim Care Community Health. 2021 Jan-Dec;12:21501327211020973. PubMed PMID: 34053368
  • Fisher DA, Karlitz JJ, Jeyakumar S, Smith N, Limburg P, Lieberman D, Fendrick AM. Real-world cost-effectiveness of stool-based colorectal cancer screening in a Medicare population. J Med Econ. 2021 Jan-Dec;24(1):654-664. PubMed PMID: 33902366
  • Montminy EM, Zhou M, Maniscalco L, Abualkhair W, Kim MK, Siegel RL, Wu XC, Itzkowitz SH, Karlitz JJ. Contributions of Adenocarcinoma and Carcinoid Tumors to Early-Onset Colorectal Cancer Incidence Rates in the United States. Ann Intern Med. 2021 Feb;174(2):157-166. PubMed PMID: 33315473
  • Parekh A, Hochheimer CJ, Espinoza JM, Karlitz JJ, Lewis CL, Wani S, Patel SG. Primary Care Provider Knowledge and Practice in Risk Assessment for Early Age Onset Colorectal Cancer: Opportunities for Improvement. J Cancer Prev. 2021 Dec 30;26(4):298-303. PubMed PMID: 35047456
  • Shah ED, Amann ST, Karlitz JJ. The Time Is Now: A Guide to Sustainable Telemedicine During COVID-19 and Beyond. Am J Gastroenterol. 2020 Sep;115(9):1371-1375. PubMed PMID: 32694293
  • Montminy EM, Jang A, Conner M, Karlitz JJ. Screening for Colorectal Cancer. Med Clin North Am. 2020 Nov;104(6):1023-1036. PubMed PMID: 33099448
  • Molmenti CL, Kolb JM, Karlitz JJ. Advanced Colorectal Polyps on Colonoscopy: A Trigger for Earlier Screening of Family Members. Am J Gastroenterol. 2020 Mar;115(3):311-314. PubMed PMID: 31977326
  • Abualkhair WH, Zhou M, Ochoa CO, Lacayo L, Murphy C, Wu XC, Karlitz JJ. Geographic and intra-racial disparities in early-onset colorectal cancer in the SEER 18 registries of the United States. Cancer Med. 2020 Dec;9(23):9150-9159. PubMed PMID: 33094553
  • Montminy EM, Karlitz JJ, Landreneau SW. Progress of colorectal cancer screening in United States: Past achievements and future challenges. Prev Med. 2019 Mar;120:78-84. PubMed PMID: 30579938
  • Dwyer AJ, Murphy CC, Boland CR, Garcia R, Hampel H, Limburg P, Lowery J, Zauber AG, Waring S, Worrall S, Perea J, Siegel R, Lee J, Molmenti C, Sears CL, Buckhaults P, Hayes R, Hussan H, de Miranda N, Palles C, Diaz L, Song M, Cercek A, Lieu CH, Patel SG, Karlitz JJ, Cao Y, Demb J, Blatchford P, Risendal B, Weltzien E, Wali A, Daschner P, Loomans-Kropp H, Flores R, Levell CL, Wehling K, Martin J, Pesmen C, Kuchar V, Soisson R, Davis A, Ahnen D. A Summary of the Fight Colorectal Cancer Working Meeting: Exploring Risk Factors and Etiology of Sporadic Early-Age Onset Colorectal Cancer. Gastroenterology. 2019 Aug;157(2):280-288. PubMed PMID: 31095950
  • Karlitz JJ, Oliphant AB, Greenwald DA, Pochapin MB. The American College of Gastroenterology and the 80% by 2018 Colorectal Cancer Initiative: A Multifaceted Approach to Maximize Screening Rates. Am J Gastroenterol. 2017 Sep;112(9):1360-1362. PubMed PMID: 28786408
  • Montminy EM, Landreneau SW, Karlitz JJ. First report of small cell lung cancer with PTHrP-induced hypercalcemic pancreatitis causing disconnected duct syndrome. World J Clin Oncol. 2017 Oct 10;8(5):420-424. PubMed PMID: 29067279
  • Charlton ME, Karlitz JJ, Schlichting JA, Chen VW, Lynch CF. Factors Associated With Guideline-recommended KRAS Testing in Colorectal Cancer Patients: A Population-based Study. Am J Clin Oncol. 2017 Oct;40(5):498-506. PubMed PMID: 25844824
  • Parsons HM, Chu Q, Karlitz JJ, Stevens JL, Harlan LC. Adoption of Sorafenib for the Treatment of Advanced-Stage Hepatocellular Carcinoma in Oncology Practices in the United States. Liver Cancer. 2017 Jun;6(3):216-226. PubMed PMID: 29234628
  • Charlton ME, Kahl AR, Greenbaum AA, Karlitz JJ, Lin C, Lynch CF, Chen VW. KRAS Testing, Tumor Location, and Survival in Patients With Stage IV Colorectal Cancer: SEER 2010-2013. J Natl Compr Canc Netw. 2017 Dec;15(12):1484-1493. PubMed PMID: 29223986
  • Noll A, Parekh PJ, Karlitz JJ. Diagnosis of Lynch syndrome before colorectal resection: does it matter?. Tech Coloproctol. 2016 Apr;20(4):203-5. PubMed PMID: 26894490
  • Rico A, Pollack LA, Thompson TD, Hsieh MC, Wu XC, Karlitz JJ, West DW, Rainey JM, Chen VW. KRAS testing and first-line treatment among patients diagnosed with metastatic colorectal cancer using population data from ten National Program of Cancer Registries in the United States. J Cancer Res Ther (Manch). 2016;5(2):7-13. PubMed PMID: 28626587
  • Karlitz JJ, Hsieh MC, Liu Y, Blanton C, Schmidt B, Jessup JM, Wu XC, Chen VW. Population-Based Lynch Syndrome Screening by Microsatellite Instability in Patients =50: Prevalence, Testing Determinants, and Result Availability Prior to Colon Surgery. Am J Gastroenterol. 2015 Jul;110(7):948-55. PubMed PMID: 25601013
  • Shaban A, Hymel B, Chavez-Keatts M, Karlitz JJ, Martin-Schild S. Recurrent posterior strokes in inflammatory bowel disease patients. Gastroenterol Res Pract. 2015;2015:672460. PubMed PMID: 25784930
  • Karlitz J, Provenzale D. Invited comment on Warrier et al: hereditary colorectal cancer screening and management practices by colorectal surgeons. Tech Coloproctol. 2014 Mar;18(3):313-4. PubMed PMID: 24127044
  • Chen VW, Hsieh MC, Charlton ME, Ruiz BA, Karlitz J, Altekruse SF, Ries LA, Jessup JM. Analysis of stage and clinical/prognostic factors for colon and rectal cancer from SEER registries: AJCC and collaborative stage data collection system. Cancer. 2014 Dec 1;120 Suppl 23(0 0):3793-806. PubMed PMID: 25412391
  • Karlitz JJ, Li ST, Holman RP, Rice MC. EBV-associated colitis mimicking IBD in an immunocompetent individual. Nat Rev Gastroenterol Hepatol. 2011 Jan;8(1):50-4. PubMed PMID: 21119609
  • Gupta MK, Karlitz JJ, Raines DL, Florman SS, Lopez FA. Clinical case of the month. Heterotopic pancreas. J La State Med Soc. 2010 Nov-Dec;162(6):310-3. PubMed PMID: 21294486
  • Feuerstadt P, Bunim AL, Garcia H, Karlitz JJ, Massoumi H, Thosani AJ, Pellecchia A, Wolkoff AW, Gaglio PJ, Reinus JF. Effectiveness of hepatitis C treatment with pegylated interferon and ribavirin in urban minority patients. Hepatology. 2010 Apr;51(4):1137-43. PubMed PMID: 20049907
  • Karlitz JJ. The effectiveness of colonoscopy in reducing mortality from colorectal cancer. Ann Intern Med. 2009 Jun 2;150(11):816; author reply 819-20. PubMed PMID: 19487719
  • Karlitz JJ, Tepler IA, Tanaka KE. Endometriosis with colonic wall invasion. Clin Gastroenterol Hepatol. 2007 Mar;5(3):A30. PubMed PMID: 16904947
  • Keller CE, Gamboa ET, Hays AP, Karlitz J, Lowe G, Green PH, Bhagat G. Fatal CNS vasculopathy in a patient with refractory celiac disease and lymph node cavitation. Virchows Arch. 2006 Feb;448(2):209-13. PubMed PMID: 16175383
  • Montminy EM, Zhou M, Long C, Wani S, Patel SG, Karlitz JJ. Impact of Carcinoid and Appendiceal Site Inclusion on Early Onset Colon Cancer Incidence Rate Analysis in the United States. Clin Gastroenterol Hepatol. 2022 Oct 21. [Epub ahead of print] PubMed PMID: 36273798
  • Montminy EM, Zhou M, Maniscalco L, Penrose H, Yen T, Patel SG, Wu XC, Karlitz JJ. Trends in the Incidence of Early-Onset Colorectal Adenocarcinoma Among Black and White US Residents Aged 40 to 49 Years, 2000-2017. JAMA Netw Open. 2021 Nov 1;4(11):e2130433. PubMed PMID: 34751760
  • Abualkhair WH, Zhou M, Ahnen D, Yu Q, Wu XC, Karlitz JJ. Trends in Incidence of Early-Onset Colorectal Cancer in the United States Among Those Approaching Screening Age. JAMA Netw Open. 2020 Jan 3;3(1):e1920407. PubMed PMID: 32003823
  • Karlitz JJ, Blanton C, Andrews P, Chen VW, Wu XC, Fontham E. Colorectal Cancer Incidence Rates in the Louisiana Acadian Parishes Demonstrated to be Among the Highest in the United States. Clin Transl Gastroenterol. 2014 Oct 2;5(10):e60. doi: 10.1038/ctg.2014.10. PMID: 25273154
  • Karlitz JJ, Sherrill MR, DiGiacomo DV, Hsieh MC, Schmidt B, Wu XC, Chen VW. Factors Associated With the Performance of Extended Colonic Resection vs. Segmental Resection in Early-Onset Colorectal Cancer: A Population-Based Study. Clin Transl Gastroenterol. 2016 Apr 14;7(4):e163. doi: 10.1038/ctg.2016.17. PMID: 27077958
  • Noll A, J Parekh P, Zhou M, Weber TK, Ahnen D, Wu XC, Karlitz JJ. Barriers to Lynch Syndrome Testing and Preoperative Result Availability in Early-onset Colorectal Cancer: A National Physician Survey Study. Clin Transl Gastroenterol. 2018 Sep 20;9(9):185. doi: 10.1038/s41424-018-0047-y. PMID: 30237431
  • Karlitz JJ, Phillips A, Sorrells KS, Rao S. Genetic Analysis of Archived Tumor Specimens for Hereditary Colorectal Cancer Syndromes in the Cajuns of Louisiana, a US Founder Population. Clin Transl Gastroenterol. 2021 Sep 21;12(9):e00392. doi: 10.14309/ctg.0000000000000392. PMID: 34545850
  • Wang CP, Lin JJ, Shah SC, Kim MK; Colorectal Cancer Screening Working Group (Montminy EM, Rustgi SD, Karlitz JJ, Itzkowitz SH). Geographic Variation in Colorectal Cancer Incidence Among Asian Americans: A Population-Based Analysis 2006-2016. Clin Gastroenterol Hepatol. 2023 Feb;21(2):543-545.e3. doi: 10.1016/j.cgh.2022.01.026. Epub 2022 Feb 3.

Practice Locations

Hospital Affiliation
  • University of Colorado Hospital
  • Veterans Affairs Medical Center

Specialty Information

Specialties
  • Gastroenterology, Board Certification (2006, 2016)

School of Medicine

CU Anschutz
Fitzsimons Building

13001 East 17th Place

Aurora, CO 80045

303.724.5375

School
General
Students