Sarkis Derderian, MD

Assistant Professor, Surgery-Peds Surgery


FacultyPhoto
Medical School
  • MD, Medical University of South Carolina College of Medicine (2010)
Undergraduate School
  • BA/BS, George Washington University (DC) (2005)
Residency
  • Emory University School of Medicine Program, Surgery
Fellowships
  • University of California (San Francisco) School of Medicine Program, Fetal Surgery (2012)
  • University of Colorado (Children's Hospital Colorado) Program, Surgical Critical Care (2018)
  • University of Colorado (Children's Hospital Colorado) Program, Bariatrics (2019)
  • University of Colorado (Children's Hospital Colorado) Program, Pediatric Surgery (2021)
Department
Surgery-Peds Surgery

Professional Titles

  • Assistant Professor of Surgery

Research Interests

The role of microRNAs in regulating the pathogenesis of fetal growth restriction

Publications

  • Bliss DP Jr, Strandness TB, Derderian SC, Kaizer AM, Partrick DA. Ultrasound-guided erector spinae plane block versus thoracic epidural analgesia: Postoperative pain management after Nuss repair for pectus excavatum. J Pediatr Surg. 2021 Oct 30. [Epub ahead of print] PubMed PMID: 34949445
  • In utero Gastric Perforation from Combined Duodenal and Esophageal Atresia without Consistent Polyhydramnios
  • Adolescent Blunt Solid Organ Injury: Differences in Management Strategies and Outcomes Between Pediatric and Adult Trauma Centers
  • Niemiec SM, Louiselle AE, Phillips R, Gien J, Zaretsky MV, Derderian SC, Liechty KW, Meyers ML. Third-trimester percentage predicted lung volume and percentage liver herniation as prognostic indicators in congenital diaphragmatic hernia. Pediatr Radiol. 2022 Oct 27. [Epub ahead of print] PubMed PMID: 36289070
  • Vaughn AE, Louiselle AE, Tong S, Niemiec SM, Ahmad S, Zaretsky M, Galan HL, Behrendt N, Wilkinson CC, O'Neill B, Handler M, Derderian SC, Mirsky DM, Liechty KW. Early outcomes of a myofascial repair technique for fetal myelomeningocele. J Pediatr Surg. 2022 Sep 26. [Epub ahead of print] PubMed PMID: 36289034
  • Louiselle AE, Niemiec SM, Derderian SC, SooHoo MM, Acker SN. The effect of single ventricle congenital heart disease on recurrence risk of pneumatosis intestinalis in neonates. Pediatr Surg Int. 2022 Oct;38(10):1399-1404. PubMed PMID: 35852591
  • Derderian SC, Meier M, Bensard DD, Partrick DA, Acker SN. Adolescent blunt solid organ injury: Differences in management strategies and outcomes between pediatric and adult trauma centers. Am J Surg. 2022 Jul;224(1 Pt A):13-17. PubMed PMID: 35232541
  • Smiley K, Partrick DA, Corkum KS, Derderian SC. Torsed ectopic intra-abdominal liver rest within an adolescent female. J Surg Case Rep. 2022 Feb;2022(2):rjac036. PubMed PMID: 35154641
  • Roach JP, Derderian SC, Ketzer J, Benge M, Kaizer A, Bischoff A. The pediatric surgery match from the applicant perspective. J Pediatr Surg. 2022 Nov;57(11):589-591. PubMed PMID: 35105454
  • Bliss DP Jr, Strandness TB, Derderian SC, Kaizer AM, Partrick DA. Ultrasound-guided erector spinae plane block versus thoracic epidural analgesia: Postoperative pain management after Nuss repair for pectus excavatum. J Pediatr Surg. 2022 Feb;57(2):207-212. PubMed PMID: 34949445
  • Vaughn AE, Lyttle BD, Tran W, Derderian SC, Liechty KW, Gien J. Surgical Necrotizing Enterocolitis - Can We Predict the Need for Gastrostomy Tube Placement?. J Surg Res. 2023 Nov 27;295:168-174. [Epub ahead of print] PubMed PMID: 38016270
  • Gallagher LT, Lyttle BD, Meyers ML, Gien J, Zaretsky MV, Galan HL, Behrendt N, Liechty KW, Derderian SC. Fetal lung volumes measured by MRI predict pulmonary morbidity among infants with giant omphaloceles. Prenat Diagn. 2023 Nov;43(12):1514-1519. PubMed PMID: 37807606
  • Gallagher LT, Wright CJ, Lehmann T, Khailova L, Zarate M, Lyttle BD, Liechty KW, Derderian SC. Angiogenic and Inflammatory microRNA Regulation in a Mouse Model of Fetal Growth Restriction. J Surg Res. 2023 Dec;292:234-238. PubMed PMID: 37657141
  • Jin ES, Malloy CR, Sharma G, Finn E, Fuller KNZ, Reyes YG, Lovell MA, Derderian SC, Schoen JA, Inge TH, Cree MG. Glycerol as a precursor for hepatic de novo glutathione synthesis in human liver. Redox Biol. 2023 Jul;63:102749. PubMed PMID: 37224695
  • Speck KE, Kulaylat AN, Baerg JE, Acker SN, Baird R, Beres AL, Chang H, Derderian SC, Englum B, Gonzalez KW, Kawaguchi A, Kelley-Quon L, Levene TL, Rentea RM, Rialon KL, Ricca R, Somme S, Wakeman D, Yousef Y, St Peter SD, Lucas DJ. Evaluation and Management of Primary Spontaneous Pneumothorax in Adolescents and Young Adults: A Systematic Review From the APSA Outcomes & Evidence-Based Practice Committee. J Pediatr Surg. 2023 Oct;58(10):1873-1885. PubMed PMID: 37130765
  • Gallagher LT, Lyttle BD, Dawson-Gore C, Vaughn AE, Breckenfelder C, Reynolds R, Zaretsky MV, Derderian SC. The Effect of Steroids on Prenatally Diagnosed Lung Lesions. J Pediatr Surg. 2023 Nov 13. [Epub ahead of print] PubMed PMID: 38042733
  • Rentea RM, Renaud E, Ricca R, Derderian C, Englum B, Kawaguchi A, Gonzalez K, Speck KE, Villalona G, Kulaylat A, Wakeman D, Yousef Y, Rialon K, Somme S, Lucas D, Levene T, Chang H, Baerg J, Acker S, Fisher J, Kelley-Quon LI, Baird R, Beres AL. Surgical Management of Ulcerative Colitis in Children and Adolescents: A Systematic Review from the APSA Outcomes and Evidence-Based Practice Committee. J Pediatr Surg. 2023 Oct;58(10):1861-1872. PubMed PMID: 36941170
  • Niemiec SM, Louiselle AE, Phillips R, Gien J, Zaretsky MV, Derderian SC, Liechty KW, Meyers ML. Third-trimester percentage predicted lung volume and percentage liver herniation as prognostic indicators in congenital diaphragmatic hernia. Pediatr Radiol. 2023 Mar;53(3):479-486. PubMed PMID: 36289070
  • Vaughn AE, Louiselle AE, Tong S, Niemiec SM, Ahmad S, Zaretsky M, Galan HL, Behrendt N, Wilkinson CC, O'Neill B, Handler M, Derderian SC, Mirsky DM, Liechty KW. Early outcomes of a myofascial repair technique for fetal myelomeningocele. J Pediatr Surg. 2023 Jan;58(1):20-26. PubMed PMID: 36289034
  • Gallagher LT, Lyttle B, KW Liechty, SC Derderian. The Effects of Steroids for Prenatally Diagnosed Congenital Pulmonary Airway Malformations. J Pediatr Surg
  • Reppucci M, Prendergast C, Flynn K, Scarbro S, Derderian SC, Diaz-Miron J. Trainee educational curriculum to standardize central venous catheter repair. BMC Med Educ. 2023 Dec 19;23(1):978. PubMed PMID: 38115058
  • Vazquez N, Lee C, Valenzuela I, Phan TP, Derderian C, Chávez M, Mooney NA, Demeter J, Aziz-Zanjani MO, Cusco I, Codina M, Martínez-Gil N, Valverde D, Solarat C, Buel AL, Thauvin-Robinet C, Steichen E, Filges I, Joset P, De Geyter J, Vaidyanathan K, Gardner T, Toriyama M, Marcotte EM, Roberson EC, Jackson PK, Reiter JF, Tizzano EF, Wallingford JB. The human ciliopathy protein RSG1 links the CPLANE complex to transition zone architecture. bioRxiv. 2024 Sep 26. PubMed PMID: 39386566
  • Kulaylat AN, Lucas DJ, Chang HL, Derderian SC, Beres AL, Ham PB 3rd, Huerta CT, Sulkowski JP, Wakeman D, Englum BR, Gulack BC, Acker SN, Gonzalez KW, Levene TL, Christison-Lagay E, Mansfield SA, Yousef Y, Pennell CP, Russell KW, Rentea RM, Tashiro J, Diesen DL, Alemayehu H, Ricca R, Kelley-Quon L, Rialon KL. Evaluation and Management of Biliary Dyskinesia in Children and Adolescents: A Systematic Review From the APSA Outcomes and Evidence-Based Committee. J Pediatr Surg. 2024 Aug 14;:161678. [Epub ahead of print] PubMed PMID: 39227244
  • Lyttle BD, Derderian SC, Neuberger I, Behrendt NJ, Pickett-Nairne K, Francom CR, Liechty KW, Meyers ML. Comparison of best landmarks for calculating fetal jaw measurements by ultrasound and MRI in micrognathia. Pediatr Radiol. 2024 Aug 24. [Epub ahead of print] PubMed PMID: 39179930
  • Smith CA, Rialon KL, Kawaguchi A, Dellinger MB, Goldin AB, Acker S, Kulaylat AN, Chang H, Russell K, Wakeman D, Derderian SC, Englum BR, Polites SF, Lucas DJ, Ricca R, Levene TL, Sulkowski JP, Kelley-Quon LI, Tashiro J, Christison-Lagay ER, Mansfield SA, Beres AL, Huerta CT, Ben Ham P 3rd, Yousef Y, Rentea RM. Classification and Surgical Management of Anorectal Malformations: A Systematic Review and Evidence-based Guideline From the APSA Outcomes and Evidence-based Practice Committee. J Pediatr Surg. 2024 Oct;59(10):161598. PubMed PMID: 38997855
  • Slidell MB, McAteer J, Miniati D, Sømme S, Wakeman D, Rialon K, Lucas D, Beres A, Chang H, Englum B, Kawaguchi A, Gonzalez K, Speck E, Villalona G, Kulaylat A, Rentea R, Yousef Y, Darderian S, Acker S, St Peter S, Kelley-Quon L, Baird R, Baerg J. Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations (A Systematic Review From the American Pediatric Surgical Association Outcomes & Evidence Based Practice Committee). J Pediatr Surg. 2024 Aug;59(8):1408-1417. PubMed PMID: 38796391
  • Gallagher LT, Bardill J, Sucharov CC, Wright CJ, Karimpour-Fard A, Zarate M, Breckenfelder C, Liechty KW, Derderian SC. Dysregulation of miRNA-mRNA expression in fetal growth restriction in a caloric restricted mouse model. Sci Rep. 2024 Mar 7;14(1):5579. PubMed PMID: 38448721
  • Vaughn AE, Lyttle BD, Louiselle AE, Cooper E, Niemiec SM, Phillips R, Hilton SA, Kinsella JP, Gien J, Derderian SC, Liechty KW. Muscle Flap Technique Safe for On-ECMO Congenital Diaphragmatic Hernia Repair. J Pediatr Surg. 2024 May;59(5):962-968. PubMed PMID: 38160185
  • Gallagher LT, Lyttle BD, Dawson-Gore C, Vaughn AE, Breckenfelder C, Reynolds R, Zaretsky MV, Derderian SC. The Effect of Steroids on Prenatally Diagnosed Lung Lesions. J Pediatr Surg. 2024 May;59(5):969-974. PubMed PMID: 38042733
  • Vaughn AE, Lyttle BD, Tran W, Derderian SC, Liechty KW, Gien J. Surgical Necrotizing Enterocolitis - Can We Predict the Need for Gastrostomy Tube Placement?. J Surg Res. 2024 Mar;295:168-174. PubMed PMID: 38016270
  • Breckenfelder C, Dawson-Gore CC, Galambos C, Corkum KS, Partrick D, Derderian SC. Congenital Pulmonary Airway Malformation Associated with Papillary Adenocarcinoma. Ann Thorac Surg Short Reports (In press).

Practice Locations

Children's Hospital Colorado - Colorado Fetal Care Center
13123 E 16th Ave, B735
Aurora, CO 80045
720-777-4463

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234

Hospital Affiliation
  • Children's Hospital Colorado
  • University of Colorado Hospital

Center Affiliations

Specialty Information

Specialties
  • Pediatric Surgery, Board Certification
  • General Surgery, Board Certification (0001)
  • Surgical Critical Care, Board Certification (0001)
  • Pediatric Surgery, Board Certification (0001)
  • Fetal Surgery, Specialized Training (0001)
Conditions & Treatments
  • Pregnancy and Reproduction - Maternal and Fetal Health
  • Pregnancy and Reproduction
  • Pregnancy and Reproduction - Prenatal Care
  • Surgery - Complex Abdominal/Open Surgery
  • Surgery
  • Surgery - Fetal
  • Surgery - Laparoscopic Surgery
  • Surgery - Minimally Invasive Thoracic Surgery
Clinical Interests
Fetal anomalies, fetal myelomeningocele (MMC), congenital diaphragmatic hernia (CDH), congenital pulmonary airway malformation (CPAM), giant omphalocele, sacrococcygeal teratoma

Care Philosophy
My care philosophy is to offer the absolute best care I can for a family. I work closely with multiple sub-specialist to assure that we provide the very best outcome for our patients.