Daniel Kramer, MD

Professional Titles

• Assistant Professor

Research Interests

His research areas are focused on the interpretation of neural signals and the communication between brain areas, particularly to produce movement and somatosensation. He spent a dedicated research year under an NIH grant at CalTech, working on brain computer interface, where the human brain interfaces directly with machines to restore motor and sensory function to paralyzed individuals, and went on to continue this type of work at Stanford. He is currently collaborating to develop a brain computer interface program at CU.

Publications

• Kern DS, Kramer DR. Neurohistological findings in deep brain stimulation: Current knowledge and gaps. Parkinsonism Relat Disord. 2025 Jan 22;:107297. [Epub ahead of print] PubMed PMID: 39870555
• Baker SK, Radcliffe EM, Kramer DR, Ojemann S, Case M, Zarns C, Holt-Becker A, Raike RS, Baumgartner AJ, Kern DS, Thompson JA. Comparison of beta peak detection algorithms for data-driven deep brain stimulation programming strategies in Parkinson's disease. NPJ Parkinsons Dis. 2024 Aug 9;10(1):150. PubMed PMID: 39122725
• Ryan MV, Satzer D, Ojemann SG, Kramer DR, Thompson JA. Neurophysiologic Characteristics of the Anterior Nucleus of the Thalamus during Deep Brain Stimulation Surgery for Epilepsy. Stereotact Funct Neurosurg. 2024;102(5):293-307. PubMed PMID: 39008968
• Bayman E, Chee K, Mendlen M, Denman DJ, Tien RN, Ojemann S, Kramer DR, Thompson JA. Subthalamic nucleus synchronization between beta band local field potential and single-unit activity in Parkinson's disease. Physiol Rep. 2024 May;12(9):e16001. PubMed PMID: 38697943
• Chee K, Hirt L, Mendlen M, Machnik J, Razmara A, Bayman E, Thompson JA, Kramer DR. Brain Shift during Staged Deep Brain Stimulation for Movement Disorders. Stereotact Funct Neurosurg. 2024;102(2):83-92. PubMed PMID: 38286119
• Lamorie-Foote K, Kramer DR, Sundaram S, Cavaleri J, Gilbert ZD, Tang AM, Bashford L, Liu CY, Kellis S, Lee B. Primary somatosensory cortex organization for engineering artificial somatosensation. Neurosci Res. 2024 Jul;204:1-13. PubMed PMID: 38278220
• Lewis S, Radcliffe E, Ojemann S, Kramer DR, Hirt L, Case M, Holt-Becker AB, Raike R, Kern DS, Thompson JA. Pilot Study to Investigate the Use of In-Clinic Sensing to Identify Optimal Stimulation Parameters for Deep Brain Stimulation Therapy in Parkinson's Disease. Neuromodulation. 2024 Apr;27(3):509-519. PubMed PMID: 36797194
• Chee K, Hirt L, Mendlen M, Machnik J, Razmara A, Bayman E, Thompson JA, Kramer DR. Brain Shift during Staged Deep Brain Stimulation for Movement Disorders. Stereotact Funct Neurosurg. 2024 Jan 29;:1-10. [Epub ahead of print] PubMed PMID: 38286119
• Lamorie-Foote K, Kramer DR, Sundaram S, Cavaleri J, Gilbert ZD, Tang AM, Bashford L, Liu CY, Kellis S, Lee B. Primary somatosensory cortex organization for engineering artificial somatosensation. Neurosci Res. 2024 Jan 24. [Epub ahead of print] PubMed PMID: 38278220
• Thompson JA, Hirt L, David-Gerecht P, Fasano A, Kramer DR, Ojemann SG, Kern DS. Comparison of Monopolar Review to Fixed Parameter Fractionation in Deep Brain Stimulation. Mov Disord Clin Pract. 2023 Jun;10(6):987-991. PubMed PMID: 37332654
• Radcliffe EM, Baumgartner AJ, Kern DS, Al Borno M, Ojemann S, Kramer DR, Thompson JA. Oscillatory beta dynamics inform biomarker-driven treatment optimization for Parkinson's disease. J Neurophysiol. 2023 Jun 1;129(6):1492-1504. PubMed PMID: 37198135
• Chee K, Razmara A, Geller AS, Harris WB, Restrepo D, Thompson JA, Kramer DR. Corrigendum: The role of the piriform cortex in temporal lobe epilepsy: A current literature review. Front Neurol. 2023;14:1148230. PubMed PMID: 36908616
• Lewis S, Radcliffe E, Ojemann S, Kramer DR, Hirt L, Case M, Holt-Becker AB, Raike R, Kern DS, Thompson JA. Pilot Study to Investigate the Use of In-Clinic Sensing to Identify Optimal Stimulation Parameters for Deep Brain Stimulation Therapy in Parkinson's Disease. Neuromodulation. 2023 Feb 14. [Epub ahead of print] PubMed PMID: 36797194
• Tekriwal A, Baker S, Christensen E, Petersen-Jones H, Tien RN, Ojemann SG, Kern DS, Kramer DR, Felsen G, Thompson JA. Quantifying neuro-motor correlations during awake deep brain stimulation surgery using markerless tracking. Sci Rep. 2022 Oct 27;12(1):18120. PubMed PMID: 36302865
• Baker S, Tekriwal A, Felsen G, Christensen E, Hirt L, Ojemann SG, Kramer DR, Kern DS, Thompson JA. Automatic extraction of upper-limb kinematic activity using deep learning-based markerless tracking during deep brain stimulation implantation for Parkinson's disease: A proof of concept study. PLoS One. 2022;17(10):e0275490. PubMed PMID: 36264986
• Kern D, Korsmo M, Baumgartner AJ, Kramer D, Ojemann S, Case M, Holt-Becker AB, Raike R, Thompson JA. Methylphenidate effects on a clinically informative oscillatory signal within the subthalamic nucleus in Parkinson's disease during deep brain stimulation programming. Brain Stimul. 2022 May-Jun;15(3):747-749. PubMed PMID: 35526817
• Hirt L, Kern DS, Ojemann S, Grassia F, Kramer D, Thompson JA. Use of Three-Dimensional Printed Brain Models During Deep Brain Stimulation Surgery Consultation for Patient Health Literacy: A Randomized Controlled Investigation. World Neurosurg. 2022 Jun;162:e526-e533. PubMed PMID: 35306197
• Razmara A, Idlett-Ali S, Chee K, Shrestha K, Bayman E, Thompson J, Jameson L, Ojemann S, Kramer D. Transient cardiac asystole during vagus nerve stimulator implantation: A case report. Surg Neurol Int. 2022;13:131. PubMed PMID: 35509543
• Chee K, Razmara A, Geller AS, Harris WB, Restrepo D, Thompson JA, Kramer DR. The role of the piriform cortex in temporal lobe epilepsy: A current literature review. Front Neurol. 2022;13:1042887. PubMed PMID: 36479052
• Tien RN, Tekriwal A, Calame DJ, Platt JP, Baker S, Seeberger LC, Kern DS, Person AL, Ojemann SG, Thompson JA, Kramer DR. Deep learning based markerless motion tracking as a clinical tool for movement disorders: Utility, feasibility and early experience. Frontiers in Signal Processing. 2022 Sept 29. Vol 2

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

UCHealth Neurosurgery - Anschutz Medical Campus
1635 Aurora Court
Anschutz Outpatient Pavilion, 4th Fl
Aurora, CO 80045
720-848-2080

Hospital Affiliation

• University of Colorado Hospital
• UCHealth Highlands Ranch Hospital

Specialty Information

Specialties

• Neurological Surgery

Conditions & Treatments

• Brain and Nervous System - Deep Brain Stimulation
• Brain and Nervous System
• Brain and Nervous System - Epilepsy
• Brain and Nervous System - General Neurosurgery
• Brain and Nervous System - Movement Disorders
• Brain and Nervous System - Parkinson's Disease
• Brain and Nervous System - Trigeminal Neuralgia
• Brain and Nervous System - Brain Tumors
• Brain and Nervous System - Hydrocephalus
• Brain and Nervous System - Traumatic and Acquired Brain Injuries